Page last updated: 2024-10-18

dimethyl sulfoxide and Necrosis

dimethyl sulfoxide has been researched along with Necrosis in 61 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"To study whether formulation influences biodistribution, necrosis avidity and tumoricidal effects of the radioiodinated hypericin, a necrosis avid agent for a dual-targeting anticancer radiotherapy."7.80Radioiodinated hypericin: its biodistribution, necrosis avidity and therapeutic efficacy are influenced by formulation. ( Alpizar, YA; Bauwens, M; Chen, F; Cona, MM; de Witte, P; Feng, Y; Li, J; Ni, Y; Oyen, R; Sun, Z; Talavera, K; Verbruggen, A; Zhang, J, 2014)
"We induced acute skeletal muscle necrosis in rats using bupivacaine hydrochloride and found that both 2,5- and 2,3-dihydroxybenzoic acid significantly increased in skeletal muscle."7.71Bupivacaine hydrochloride induces muscle fiber necrosis and hydroxyl radical formation-dimethyl sulphoxide reduces hydroxyl radical formation. ( Iguchi, H; Kinoshita, M; Nomoto, N; Sugimoto, H; Wakata, N, 2001)
"Experiments with two models of intestinal ischemia were performed in order to examine the protective effect of dimethyl sulfoxide (DMSO)."7.66The protective effect of dimethyl sulfoxide in experimental ischemia of the intestine. ( Bernheim, J; Kedar, I; Ravid, M; Van-Dyk, D, 1983)
" We have used a rat skin model to study the protection afforded by dimethyl sulfoxide and alpha-tocopherol (vitamin E) against Adriamycin-induced skin necrosis."7.66Protection against adriamycin-induced skin necrosis in the rat by dimethyl sulfoxide and alpha-tocopherol. ( Appel, PL; Powis, G; Scott, M; Svingen, BA, 1981)
"Necrosis was evident in the DXR-treated group and some slides showed necrosis involving the fascia."5.36Melatonin ameliorates doxorubicin-induced skin necrosis in rats. ( Citak, EC; Karslioglu, Y; Kesik, V; Kismet, E; Koseoglu, V; Kurt, B; Tunc, T, 2010)
" Human osteosarcoma MG63 cells were encapsulated in sodium alginate fiber constructs with wetspinning method and exposed to different formulations of cryopreservation media, containing dimethyl sulfoxide (DMSO), glycerol, and trehalose."3.88Effect of Cryopreservation on Cell-Laden Hydrogels: Comparison of Different Cryoprotectants. ( Bonani, W; Cagol, N; Maniglio, D; Migliaresi, C; Motta, A, 2018)
"Hypericin (Hy) has shown great promise as a necrosis-avid agent in cancer imaging and therapy."3.81Evaluation of hypericin: effect of aggregation on targeting biodistribution. ( Gao, M; Huang, D; Ji, Y; Jiang, C; Li, Y; Liu, W; Liu, X; Ni, Y; Sun, Z; Yao, N; Yin, Z; Zhang, J, 2015)
"This study investigated the effects of hyperbaric oxygen therapy (HBOT) and dimethyl sulfoxide (DMSO) in tissue necrosis, genotoxicity, and cell apoptosis."3.81Morphological study of rat skin flaps treated with subcutaneous dimethyl sulfoxide combined with hyperbaric oxygen therapy. ( Almeida, KG; Araújo, FH; Dourado, DM; Fernandes, WS; Filho, EA; Oliveira, RJ; Souza, AS, 2015)
"To study whether formulation influences biodistribution, necrosis avidity and tumoricidal effects of the radioiodinated hypericin, a necrosis avid agent for a dual-targeting anticancer radiotherapy."3.80Radioiodinated hypericin: its biodistribution, necrosis avidity and therapeutic efficacy are influenced by formulation. ( Alpizar, YA; Bauwens, M; Chen, F; Cona, MM; de Witte, P; Feng, Y; Li, J; Ni, Y; Oyen, R; Sun, Z; Talavera, K; Verbruggen, A; Zhang, J, 2014)
"We induced acute skeletal muscle necrosis in rats using bupivacaine hydrochloride and found that both 2,5- and 2,3-dihydroxybenzoic acid significantly increased in skeletal muscle."3.71Bupivacaine hydrochloride induces muscle fiber necrosis and hydroxyl radical formation-dimethyl sulphoxide reduces hydroxyl radical formation. ( Iguchi, H; Kinoshita, M; Nomoto, N; Sugimoto, H; Wakata, N, 2001)
"The role of oxygen-derived free radicals in the pathogenesis of acute pancreatitis was studied by evaluating the effects of catalase, allopurinol, and dimethylsulfoxide on diet-induced acute hemorrhagic pancreatic necrosis in mice."3.67Role of oxygen-derived free radicals in diet-induced hemorrhagic pancreatitis in mice. ( Powers, RE; Rutledge, PL; Saluja, AK; Steer, ML, 1987)
"Experiments with two models of intestinal ischemia were performed in order to examine the protective effect of dimethyl sulfoxide (DMSO)."3.66The protective effect of dimethyl sulfoxide in experimental ischemia of the intestine. ( Bernheim, J; Kedar, I; Ravid, M; Van-Dyk, D, 1983)
" We have used a rat skin model to study the protection afforded by dimethyl sulfoxide and alpha-tocopherol (vitamin E) against Adriamycin-induced skin necrosis."3.66Protection against adriamycin-induced skin necrosis in the rat by dimethyl sulfoxide and alpha-tocopherol. ( Appel, PL; Powis, G; Scott, M; Svingen, BA, 1981)
"The toxic effects of onyx, its solvent dimethyl sulphoxide (DMSO), and n-butyl 2-cyanoacrylate (NBCA) were evaluated after infusion into the subaracnoid space of a rabbit model."1.36Evaluation of the toxicity of onyx compared with n-butyl 2-cyanoacrylate in the subarachnoid space of a rabbit model: an experimental research. ( Atilla, P; Bakar, B; Hazer, BD; Kilic, K; Muftuoglu, SF; Oruckaptan, HH; Saatci, I, 2010)
"Necrosis was evident in the DXR-treated group and some slides showed necrosis involving the fascia."1.36Melatonin ameliorates doxorubicin-induced skin necrosis in rats. ( Citak, EC; Karslioglu, Y; Kesik, V; Kismet, E; Koseoglu, V; Kurt, B; Tunc, T, 2010)
"The chloroform-treated rats also developed renal tubular necrosis with large increases in plasma creatinine and urea nitrogen, which were completely ameliorated by DMSO."1.30Late dimethyl sulfoxide administration provides a protective action against chemically induced injury in both the liver and the kidney. ( Gandolfi, AJ; Lind, RC, 1997)
"Dimethyl sulfoxide (DMSO) is a well-tolerated, safe drug that is a powerful scavenger of the hydroxyl free radical."1.29Dimethyl sulfoxide increases the survival of primarily ischemic island skin flaps. ( Angel, MF; Carpenter, RJ; Morgan, RF, 1994)
"Dimethyl sulfoxide (DMSO) has been shown to reverse the effects of cerebral ischemia in the primate model."1.27The effect of hyaluronidase and dimethyl sulfoxide (DMSO) on experimental skin flap survival. ( Dinner, MI; Dowden, RV; Grossman, JA; McGonagle, BA, 1983)
"Endometrial fibrosis is a major cause of infertility in broodmares."1.27Histopathologic effects of dimethyl sulfoxide on equine endometrium. ( Frazer, GS; Rossol, TJ; Threlfall, WR; Weisbrode, SE, 1988)

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199027 (44.26)18.7374
1990's6 (9.84)18.2507
2000's10 (16.39)29.6817
2010's15 (24.59)24.3611
2020's3 (4.92)2.80

Authors

AuthorsStudies
Luginbuhl, AJ1
Hobelmann, K1
Rodin, J1
Shukla, S1
Rodeck, U1
Linnenbach, A1
Parra-Marquez, ML1
Peralta-Enriquez, A1
Peña, VG1
Charles-Lozoya, S1
Chow-Shi-Yée, M1
Grondin, M1
Ouellet, F1
Averill-Bates, DA1
Cagol, N1
Bonani, W1
Maniglio, D1
Migliaresi, C1
Motta, A1
Alalawi, WA1
Almajed, E1
Pielesz, A1
Gawłowski, A1
Biniaś, D1
Bobiński, R1
Kawecki, M1
Sama, E1
Waksmańska, W1
Cona, MM1
Alpizar, YA1
Li, J1
Bauwens, M1
Feng, Y1
Sun, Z2
Zhang, J2
Chen, F1
Talavera, K1
de Witte, P1
Verbruggen, A1
Oyen, R1
Ni, Y2
Lu, J1
He, L1
Behrends, C1
Araki, M1
Araki, K1
Jun Wang, Q1
Catanzaro, JM1
Friedman, SL1
Zong, WX1
Fiel, MI1
Li, M1
Yue, Z1
Jiang, X1
Perez-Torres, CJ1
Thotala, D1
Engelbach, JA1
Yuan, L1
Cates, J1
Gao, F1
Drzymala, RE1
Rich, KM1
Schmidt, RE1
Ackerman, JJ1
Hallahan, DE1
Garbow, JR1
Liu, X1
Jiang, C1
Li, Y1
Liu, W1
Yao, N1
Gao, M1
Ji, Y1
Huang, D1
Yin, Z1
Hebling, J1
Bianchi, L1
Basso, FG1
Scheffel, DL1
Soares, DG1
Carrilho, MR1
Pashley, DH1
Tjäderhane, L1
de Souza Costa, CA1
Kesik, V2
Yuksel, R1
Yigit, N1
Saldir, M1
Karabacak, E1
Erdem, G1
Babacan, O1
Gulgun, M1
Korkmazer, N1
Bayrak, Z1
Almeida, KG1
Oliveira, RJ1
Dourado, DM1
Filho, EA1
Fernandes, WS1
Souza, AS1
Araújo, FH1
Natarajan, SK1
Born, D1
Ghodke, B1
Britz, GW1
Sekhar, LN1
Bakar, B1
Oruckaptan, HH1
Hazer, BD1
Saatci, I1
Atilla, P1
Kilic, K1
Muftuoglu, SF1
Thirumala, S1
Gimble, JM1
Devireddy, RV1
Kurt, B1
Tunc, T1
Karslioglu, Y1
Citak, EC1
Kismet, E1
Koseoglu, V1
Langer, SW1
Trávníček, Z1
Matiková-Mal'arová, M1
Novotná, R1
Vančo, J1
Stěpánková, K1
Suchý, P1
Abrahamsen, JF1
Bakken, AM1
Bruserud, Ø1
Schrijvers, DL1
Pawa, S1
Ali, S1
Taylor, J1
Babbs, CF1
Alzghoul, MB1
Olsen, A1
Latour, M1
Pond, AL1
Hannon, K1
Guidarelli, A1
Fiorani, M1
Tommasini, I1
Cerioni, L1
Cantoni, O1
Kishioka, T1
Iida, C2
Fujii, K2
Nagae, R1
Onishi, Y1
Ichi, I2
Kojo, S2
Koga, E1
Washino, Y1
Leite, MT1
Gomes, HC1
Percário, S1
Russo, CRA1
Ferreira, LM1
El-Hage, AN1
Herman, EH1
Ferrans, VJ1
Schiefer, HB1
Hancock, DS1
Ravid, M1
Van-Dyk, D1
Bernheim, J1
Kedar, I1
Grossman, JA1
McGonagle, BA1
Dowden, RV1
Dinner, MI1
Nobbs, P1
Barr, RD1
Svingen, BA1
Powis, G1
Appel, PL1
Scott, M1
Aliab'eva, AP1
Bertelli, G1
Gozza, A1
Forno, GB1
Vidili, MG1
Silvestro, S1
Venturini, M1
Del Mastro, L1
Garrone, O1
Rosso, R1
Dini, D1
Carpenter, RJ1
Angel, MF1
Morgan, RF1
Bour, ES1
Ward, LK1
Cornman, GA1
Isom, HC1
Lind, RC1
Gandolfi, AJ1
Wakata, N1
Sugimoto, H1
Iguchi, H1
Nomoto, N1
Kinoshita, M1
Peutherer, JF1
Smith, IW1
Robertson, DH1
Petro, JA1
Graham, WP1
Miller, SH1
Overholt, T1
Fallon, T1
Lebredo, L1
Barrie, R1
Woltering, EA1
Birgin, SKh1
Afanas'ev, AN1
El'kin, GI1
Rustemova, GR1
Malamud, MIa1
Osipova, VV1
Rutledge, PL1
Saluja, AK1
Powers, RE1
Steer, ML1
Frazer, GS1
Rossol, TJ1
Threlfall, WR1
Weisbrode, SE1
Jeffery, EH1
Haschek, WM1
Delbosc, B1
Prost, F1
Montard, M1
Görög, P1
Kovács, IB1
Amlacher, E1
Danz, M1
Urban, H1
Stiller, KJ1
McFarlane, RM1
Laird, JJ1
Lamon, R1
Finlayson, AJ1
Johnson, R1
Myers, MB1
Cherry, G1
Arturson, G1
Khanna, NN1
Peterson, JE1
Samuel, A1
Jago, MV1
Dao, TL1
King, C1
Tominaga, T1
Leon, AS2
White, FC1
Bloor, CM2
Saviano, MA1
Creasey, NH1
Allenby, AC1
Schock, C1
Ward, JR1
Miller, ML1
Marcus, S1
Pitt, B1
Boyles, S1
Lewis, GP1
Westcott, B1
Somogyi, A1
Kovacs, K1
Benville, PE1
Smith, CE1
Shanks, WE1

Reviews

1 review available for dimethyl sulfoxide and Necrosis

ArticleYear
Extravasation: a dreaded complication of chemotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14 Suppl 3

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Dimethyl Sulfoxide; Doxorubicin; Extravasa

2003

Trials

1 trial available for dimethyl sulfoxide and Necrosis

ArticleYear
Topical dimethylsulfoxide for the prevention of soft tissue injury after extravasation of vesicant cytotoxic drugs: a prospective clinical study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:11

    Topics: Administration, Topical; Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Connective T

1995

Other Studies

59 other studies available for dimethyl sulfoxide and Necrosis

ArticleYear
Synthetic Triterpenoid RTA-408: Limits Radiation Damage to Normal Tissue.
    The Laryngoscope, 2022, Volume: 132, Issue:6

    Topics: Animals; Dimethyl Sulfoxide; Humans; Necrosis; Prospective Studies; Rats; Rats, Sprague-Dawley; Trit

2022
Protective effect of nitroglycerin ointment and dimethyl sulfoxide on necrosis of skin flaps in rats.
    Cirugia y cirujanos, 2023, Volume: 91, Issue:5

    Topics: Animals; Dimethyl Sulfoxide; Male; Necrosis; Nitroglycerin; Ointments; Petrolatum; Rats; Rats, Wista

2023
Control of stress-induced apoptosis by freezing tolerance-associated wheat proteins during cryopreservation of rat hepatocytes.
    Cell stress & chaperones, 2020, Volume: 25, Issue:6

    Topics: Adaptation, Physiological; Animals; Apoptosis; Caspases; Cryopreservation; Cryoprotective Agents; Cy

2020
Effect of Cryopreservation on Cell-Laden Hydrogels: Comparison of Different Cryoprotectants.
    Tissue engineering. Part C, Methods, 2018, Volume: 24, Issue:1

    Topics: Alginates; Apoptosis; Bone Neoplasms; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; G

2018
Unilateral Hard Palate Necrosis After Ascending Palatine Artery Embolization.
    The Journal of craniofacial surgery, 2018, Volume: 29, Issue:5

    Topics: Aneurysm, False; Arteries; Debridement; Dimethyl Sulfoxide; Embolization, Therapeutic; Epistaxis; Hu

2018
A Histologic Perspective on Electrical and Thermal Burn-Injured Human Skin.
    Advances in skin & wound care, 2019, Volume: 32, Issue:5

    Topics: Adult; Antioxidants; Biomarkers; Biopsy; Burns, Electric; Case-Control Studies; Dimethyl Sulfoxide;

2019
Radioiodinated hypericin: its biodistribution, necrosis avidity and therapeutic efficacy are influenced by formulation.
    Pharmaceutical research, 2014, Volume: 31, Issue:2

    Topics: Animals; Anthracenes; Antineoplastic Agents; Chemistry, Pharmaceutical; Dimethyl Sulfoxide; Iodine R

2014
NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity.
    Nature communications, 2014, May-22, Volume: 5

    Topics: Animals; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Proteins; Beclin-1; Blotting, W

2014
A GSK-3β inhibitor protects against radiation necrosis in mouse brain.
    International journal of radiation oncology, biology, physics, 2014, Jul-15, Volume: 89, Issue:4

    Topics: Aminophenols; Analysis of Variance; Animals; Brain; Colony-Forming Units Assay; Dimethyl Sulfoxide;

2014
Evaluation of hypericin: effect of aggregation on targeting biodistribution.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:1

    Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Autoradiography; Dimethyl Sulfoxide; Drug C

2015
Cytotoxicity of dimethyl sulfoxide (DMSO) in direct contact with odontoblast-like cells.
    Dental materials : official publication of the Academy of Dental Materials, 2015, Volume: 31, Issue:4

    Topics: Cell Adhesion; Cell Death; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; Flow Cytometry; Free

2015
Ozone Ameliorates Doxorubicine-Induced Skin Necrosis - results from an animal model.
    The international journal of lower extremity wounds, 2016, Volume: 15, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Biopsy; Dimethyl Sulfoxide; Disease Models, Anim

2016
Morphological study of rat skin flaps treated with subcutaneous dimethyl sulfoxide combined with hyperbaric oxygen therapy.
    Genetics and molecular research : GMR, 2015, Dec-28, Volume: 14, Issue:4

    Topics: Animals; Apoptosis; Cell Survival; Dimethyl Sulfoxide; DNA Damage; Humans; Hyperbaric Oxygenation; M

2015
Histopathological changes in brain arteriovenous malformations after embolization using Onyx or N-butyl cyanoacrylate. Laboratory investigation.
    Journal of neurosurgery, 2009, Volume: 111, Issue:1

    Topics: Brain Infarction; Cerebral Hemorrhage; Dimethyl Sulfoxide; Embolization, Therapeutic; Enbucrilate; G

2009
Evaluation of the toxicity of onyx compared with n-butyl 2-cyanoacrylate in the subarachnoid space of a rabbit model: an experimental research.
    Neuroradiology, 2010, Volume: 52, Issue:2

    Topics: Animals; Brain; Brain Edema; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enbucrilate; Lipi

2010
Evaluation of methylcellulose and dimethyl sulfoxide as the cryoprotectants in a serum-free freezing media for cryopreservation of adipose-derived adult stem cells.
    Stem cells and development, 2010, Volume: 19, Issue:4

    Topics: Adipocytes, White; Adult Stem Cells; Apoptosis; Cell Differentiation; Cell Separation; Cell Survival

2010
Melatonin ameliorates doxorubicin-induced skin necrosis in rats.
    Annals of plastic surgery, 2010, Volume: 65, Issue:2

    Topics: Animals; Dimethyl Sulfoxide; Doxorubicin; Glutathione Peroxidase; Male; Malondialdehyde; Melatonin;

2010
RE: Kesik et al: melatonin ameliorates doxorubicin-induced skin necrosis in rats.
    Annals of plastic surgery, 2010, Volume: 65, Issue:5

    Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Doxorubicin; Melatonin; Necrosis; Rats; Sensiti

2010
In vitro and in vivo biological activity screening of Ru(III) complexes involving 6-benzylaminopurine derivatives with higher pro-apoptotic activity than NAMI-A.
    Journal of inorganic biochemistry, 2011, Volume: 105, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzyl Compounds; Cell Line, Tumor; Coordination Complexe

2011
Cryopreserving human peripheral blood progenitor cells with 5-percent rather than 10-percent DMSO results in less apoptosis and necrosis in CD34+ cells.
    Transfusion, 2002, Volume: 42, Issue:12

    Topics: Antigens, CD34; Apoptosis; Blood Preservation; Cell Survival; Cryopreservation; Dimethyl Sulfoxide;

2002
Liver necrosis and fulminant hepatic failure in rats: protection by oxyanionic form of tungsten.
    Biochimica et biophysica acta, 2004, Apr-05, Volume: 1688, Issue:3

    Topics: Acetaminophen; Alkaline Phosphatase; Allopurinol; Animals; Bromobenzenes; Carbon Tetrachloride Poiso

2004
Optimization of ectopic gene expression in skeletal muscle through DNA transfer by electroporation.
    BMC biotechnology, 2004, May-18, Volume: 4

    Topics: Animals; beta-Galactosidase; Dimethyl Sulfoxide; Electroporation; Gene Expression; Injections, Intra

2004
Reduced mitochondrial formation of H(2)O(2) is responsible for resistance of dimethyl sulfoxide differentiated U937 cells to peroxynitrite.
    The international journal of biochemistry & cell biology, 2006, Volume: 38, Issue:1

    Topics: Calcium Signaling; Cell Differentiation; Dimethyl Sulfoxide; Humans; Hydrogen Peroxide; Mitochondria

2006
Effect of dimethyl sulphoxide on oxidative stress, activation of mitogen activated protein kinase and necrosis caused by thioacetamide in the rat liver.
    European journal of pharmacology, 2007, Jun-14, Volume: 564, Issue:1-3

    Topics: Animals; Ascorbic Acid; Aspartate Aminotransferases; Blotting, Western; Dimethyl Sulfoxide; Extracel

2007
Inhibitory effect of dimethyl sulfoxide (DMSO) on necrosis and oxidative stress caused by D-galactosamine in the rat liver.
    Journal of nutritional science and vitaminology, 2007, Volume: 53, Issue:2

    Topics: Alanine Transaminase; Analysis of Variance; Animals; Ascorbic Acid; Aspartate Aminotransferases; Blo

2007
Dimethyl sulfoxide as a block to the deleterious effect of nicotine in a random skin flap in the rat.
    Plastic and reconstructive surgery, 2007, Volume: 120, Issue:7

    Topics: Animals; Antioxidants; Dermatologic Surgical Procedures; Dimethyl Sulfoxide; Drug Evaluation, Precli

2007
Examination of the protective effect of ICRF-187 and dimethyl sulfoxide against acetaminophen-induced hepatotoxicity in Syrian golden hamsters.
    Toxicology, 1983, Volume: 28, Issue:4

    Topics: Acetaminophen; Alanine Transaminase; Animals; Blood Proteins; Chemical and Drug Induced Liver Injury

1983
Systemic effects of topical application of T-2 toxin in mice.
    Toxicology and applied pharmacology, 1984, Volume: 76, Issue:3

    Topics: Animals; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Duodenum; Male; Mice; Mitosis; Necros

1984
The protective effect of dimethyl sulfoxide in experimental ischemia of the intestine.
    Annals of the New York Academy of Sciences, 1983, Volume: 411

    Topics: Animals; Dimethyl Sulfoxide; Intestinal Mucosa; Intestine, Small; Ischemia; Male; Necrosis; Rats

1983
The effect of hyaluronidase and dimethyl sulfoxide (DMSO) on experimental skin flap survival.
    Annals of plastic surgery, 1983, Volume: 11, Issue:3

    Topics: Animals; Dimethyl Sulfoxide; Female; Graft Survival; Hyaluronoglucosaminidase; Necrosis; Rats; Skin;

1983
Soft-tissue injury caused by antineoplastic drugs is inhibited by topical dimethyl sulphoxide and alpha tocopherol.
    British journal of cancer, 1983, Volume: 48, Issue:6

    Topics: Administration, Topical; Animals; Connective Tissue Diseases; Dimethyl Sulfoxide; Doxorubicin; Drug

1983
Protection against adriamycin-induced skin necrosis in the rat by dimethyl sulfoxide and alpha-tocopherol.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Administration, Topical; Animals; Dimethyl Sulfoxide; Doxorubicin; Infusions, Parenteral; Male; Necr

1981
[Prevention of tissue necrosis with dimethylsulfoxide (DMSO)].
    Terapevticheskii arkhiv, 1980, Volume: 52, Issue:1

    Topics: Adult; Dimethyl Sulfoxide; Female; Humans; Necrosis; Skin

1980
Dimethyl sulfoxide increases the survival of primarily ischemic island skin flaps.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1994, Volume: 110, Issue:2

    Topics: Animals; Dimethyl Sulfoxide; Female; Free Radical Scavengers; Hydroxyl Radical; Injections, Intraper

1994
Tumor necrosis factor-alpha-induced apoptosis in hepatocytes in long-term culture.
    The American journal of pathology, 1996, Volume: 148, Issue:2

    Topics: Animals; Apoptosis; Cell Culture Techniques; Culture Media; Dimethyl Sulfoxide; DNA; Electrophoresis

1996
Late dimethyl sulfoxide administration provides a protective action against chemically induced injury in both the liver and the kidney.
    Toxicology and applied pharmacology, 1997, Volume: 142, Issue:1

    Topics: Administration, Inhalation; Administration, Oral; Alanine Transaminase; Allyl Compounds; Animals; Bi

1997
Bupivacaine hydrochloride induces muscle fiber necrosis and hydroxyl radical formation-dimethyl sulphoxide reduces hydroxyl radical formation.
    Neurochemical research, 2001, Volume: 26, Issue:7

    Topics: Anesthetics, Local; Animals; Bupivacaine; Dimethyl Sulfoxide; Free Radical Scavengers; Hydroxyl Radi

2001
Necrotising balanitis due to a generalised primary infection with herpes simplex virus type 2.
    The British journal of venereal diseases, 1979, Volume: 55, Issue:1

    Topics: Adult; Balanitis; Dimethyl Sulfoxide; Drug Combinations; Herpes Simplex; Humans; Idoxuridine; Male;

1979
Experimental and clinical studies of ulcers induced with adriamycin.
    Surgical forum, 1979, Volume: 30

    Topics: Animals; Dimethyl Sulfoxide; Doxorubicin; Fluoresceins; Humans; Injections; Necrosis; Rabbits; Ulcer

1979
DMSO protects against adriamycin-induced tissue necrosis.
    The Journal of surgical research, 1992, Volume: 53, Issue:1

    Topics: Animals; Dimethyl Sulfoxide; Doxorubicin; Male; Necrosis; Rats; Rats, Sprague-Dawley; Skin; Skin Ulc

1992
[Treatment of suppurative-necrotic complications of diabetes mellitus].
    Vestnik khirurgii imeni I. I. Grekova, 1991, Volume: 146, Issue:3

    Topics: Adult; Aged; Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; F

1991
Role of oxygen-derived free radicals in diet-induced hemorrhagic pancreatitis in mice.
    Gastroenterology, 1987, Volume: 93, Issue:1

    Topics: Acute Disease; Allopurinol; Amylases; Animals; Catalase; Choline Deficiency; Diet; Dimethyl Sulfoxid

1987
Histopathologic effects of dimethyl sulfoxide on equine endometrium.
    American journal of veterinary research, 1988, Volume: 49, Issue:10

    Topics: Animals; Dimethyl Sulfoxide; Edema; Endometrium; Epithelium; Female; Fibrosis; Horses; Inflammation;

1988
Protection by dimethylsulfoxide against acetaminophen-induced hepatic, but not respiratory toxicity in the mouse.
    Toxicology and applied pharmacology, 1988, Volume: 93, Issue:3

    Topics: Acetaminophen; Animals; Carbon Tetrachloride; Dimethyl Sulfoxide; Female; Free Radicals; Glutathione

1988
[Scanning electron microscopy of the cryopreserved corneal endothelium: a critical study in man and animals].
    Bulletin des societes d'ophtalmologie de France, 1985, Volume: 85, Issue:5

    Topics: Animals; Cornea; Dimethyl Sulfoxide; Endothelium; Freezing; Humans; Microscopy, Electron, Scanning;

1985
Effect of dimethyl sulfoxide (DMSO) on various experimental cutaneous reactions.
    Pharmacology, 1969, Volume: 2, Issue:5

    Topics: Animals; Arsenicals; Calcinosis; Dermatitis, Contact; Dihydrotachysterol; Dimethyl Sulfoxide; Dinitr

1969
Dimethyl sulphoxide as a solvent in carcinogen application with regard to the proliferative activity of the adrenal cortex.
    Experimentelle Pathologie, 1974, Volume: 9, Issue:5-6

    Topics: Adrenal Cortex; Adrenal Glands; Animals; Carcinogens; Cell Division; Dimethyl Sulfoxide; Male; Mitos

1974
Evaluation of dextran and DMSO to prevent necrosis in experimental pedicle flaps.
    Plastic and reconstructive surgery, 1968, Volume: 41, Issue:1

    Topics: Animals; Dextrans; Dimethyl Sulfoxide; Necrosis; Rats; Skin Transplantation; Surgery, Plastic; Trans

1968
Enhancement of survival in devascularized pediclexs by the use of phenoxybenzamine.
    Plastic and reconstructive surgery, 1968, Volume: 41, Issue:3

    Topics: Angiography; Animals; Collateral Circulation; Coloring Agents; Dimethyl Sulfoxide; Fluoresceins; Inj

1968
The effects of hyperbaric oxygen, dimethyl sulfoxide and Complamin on the survival of experimental skin flaps.
    Scandinavian journal of plastic and reconstructive surgery, 1970, Volume: 4, Issue:1

    Topics: Animals; Dimethyl Sulfoxide; Hyperbaric Oxygenation; Male; Necrosis; Nicotinic Acids; Rats; Regional

1970
Pathological effects of dehydroheliotridine, a metabolite of heliotridine-based pyrrolizidine alkaloids, in the young rat.
    The Journal of pathology, 1972, Volume: 107, Issue:3

    Topics: Alopecia; Animals; Atrophy; Bone Marrow; Chemical and Drug Induced Liver Injury; Dimethyl Sulfoxide;

1972
Isolation, identification, and biological study of compounds derived from 3-methylcholanthrene by irradiation in dimethyl sulfoxide.
    Cancer research, 1971, Volume: 31, Issue:10

    Topics: Adrenal Gland Diseases; Adrenal Glands; Animals; Benz(a)Anthracenes; Biotransformation; Dimethyl Sul

1971
Reduced myocardial fibrosis after dimethylsulfoxide (DMSO) treatment of isoproterenol-induced myocardial necrosis in rats.
    The American journal of the medical sciences, 1971, Volume: 261, Issue:1

    Topics: Animals; Dimethyl Sulfoxide; Heart Diseases; Hexosamines; Hydroxyproline; Ischemia; Isoproterenol; M

1971
Mechanism of action of accelerants. The effect of cutaneously-applied penetration accelerants on the skin circulation of the rat.
    The British journal of dermatology, 1971, Volume: 85, Issue:4

    Topics: Amines; Animals; Capillary Permeability; Cold Temperature; Dimethyl Sulfoxide; Ear; Epinephrine; Fur

1971
The effect of dimethyl sulfoxide on the local Shwartzman phenomenon.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Dimethyl Sulfoxide; Hemorrhage; Lipopolys

1967
The effects of dimethylsulfoxide (DMSO) on the healing of experimental myocardial necrosis.
    American heart journal, 1970, Volume: 79, Issue:3

    Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Isoproterenol; Male; Myocardial Infarction; Myo

1970
Intracellular enzymes in local lymph after chemical injury.
    British journal of pharmacology, 1970, Volume: 38, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cats; Croton Oil; Dimethyl Sulfoxide; L-

1970
Dimethyl sulfoxide, a convenient solvent of 7,12-dimethylbenz(a)anthracene for intravenous injection.
    Cancer research, 1970, Volume: 30, Issue:7

    Topics: Adenocarcinoma; Adrenal Gland Diseases; Animals; Benz(a)Anthracenes; Dimethyl Sulfoxide; Drug Stabil

1970
Some toxic effects of dimethyl sulfoxide in salmon and trout.
    Toxicology and applied pharmacology, 1968, Volume: 12, Issue:2

    Topics: Animals; Blood Cells; Dimethyl Sulfoxide; Drug Tolerance; Edema; Gills; Hematocrit; Injections, Intr

1968