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dimethyl sulfoxide and Myocardial Ischemia

dimethyl sulfoxide has been researched along with Myocardial Ischemia in 8 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with minoxidil significantly enhanced the recovery of myocardial contraction during reperfusion after ischemia."1.31Effects of minoxidil on ischemia-induced mechanical and metabolic dysfunction in dog myocardium. ( Ichihara, K; Ichinosawa, K; Kaneta, S; Kano, S; Satoh, K; Yamamoto, A, 2002)
"Nifedipine was applied in a concentration (EC50) known to reduce the contractile force by one-half of its basal value."1.29Cardioprotection by nifedipine in isolated working hearts: a comparative study on three different types of experimental ischemia. ( Mathy, MJ; Pfaffendorf, M; Pijl, AJ; van Zwieten, PA, 1993)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Preininger, MK1
Singh, M1
Xu, C1
Chin, SP1
Poey, AC1
Wong, CY1
Chang, SK1
Teh, W1
Mohr, TJ1
Cheong, SK1
Yamamoto, A1
Satoh, K2
Ichinosawa, K1
Kaneta, S2
Kano, S1
Ichihara, K2
Kosugi, T1
Aoki, Y1
Takagaki, H1
Kang, YJ1
Li, Y1
Sun, X2
Pijl, AJ1
Pfaffendorf, M1
Mathy, MJ1
van Zwieten, PA1
Rohs, TJ1
Kilgore, KS1
Georges, AJ1
Bolling, SF1
Criniti, A1
Picard, S1
Monti, F1
Dawodu, AA1
Ruvolo, G1
Puddu, PE1
Campa, PP1

Reviews

1 review available for dimethyl sulfoxide and Myocardial Ischemia

ArticleYear
Cryopreservation of Human Pluripotent Stem Cell-Derived Cardiomyocytes: Strategies, Challenges, and Future Directions.
    Advances in experimental medicine and biology, 2016, Volume: 951

    Topics: Animals; Cell Differentiation; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Disease

2016

Other Studies

7 other studies available for dimethyl sulfoxide and Myocardial Ischemia

ArticleYear
Cryopreserved mesenchymal stromal cell treatment is safe and feasible for severe dilated ischemic cardiomyopathy.
    Cytotherapy, 2010, Volume: 12, Issue:1

    Topics: Aged; Cardiomyopathy, Dilated; Cell Culture Techniques; Cells, Cultured; Cicatrix; Combined Modality

2010
Effects of minoxidil on ischemia-induced mechanical and metabolic dysfunction in dog myocardium.
    Japanese journal of pharmacology, 2002, Volume: 90, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Dimethyl Sulfoxide; Dogs; Female; Injectio

2002
Effects of radical scavengers, TA248 and TA276, on stunned myocardium in dogs: involvement of K ATP channels.
    Japanese journal of pharmacology, 2002, Volume: 90, Issue:2

    Topics: Adenosine Triphosphate; Animals; Benzopyrans; Dimethyl Sulfoxide; Dogs; Female; Free Radical Scaveng

2002
Antiapoptotic effect and inhibition of ischemia/reperfusion-induced myocardial injury in metallothionein-overexpressing transgenic mice.
    The American journal of pathology, 2003, Volume: 163, Issue:4

    Topics: Animals; Apoptosis; Caspase 3; Caspases; Cytochrome c Group; Dimethyl Sulfoxide; Enzyme Activation;

2003
Cardioprotection by nifedipine in isolated working hearts: a comparative study on three different types of experimental ischemia.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:1

    Topics: Animals; Cardiac Output; Coronary Circulation; Dimethyl Sulfoxide; Electric Stimulation; Heart; Male

1993
Postischemic function and protein kinase C signal transduction.
    The Annals of thoracic surgery, 1998, Volume: 65, Issue:6

    Topics: Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Bicarbonates; Calcium Chloride; Cardioplegi

1998
Cicletanine prevents the excitation-conduction blocks induced by terfenadine in ischemic myocardium.
    European journal of pharmacology, 1999, Oct-15, Volume: 382, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Dimethyl Sulfoxide; Drug Interactions; Epoprostenol; Female; Guinea

1999