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dimethyl sulfoxide and Myasthenia Gravis

dimethyl sulfoxide has been researched along with Myasthenia Gravis in 5 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

Research Excerpts

ExcerptRelevanceReference
"The effects of dimethyl sulfoxide (DMSO) on the humoral immune responses to acetylcholine receptors (AChR) were studied in rats with experimental autoimmune myasthenia gravis."3.67Effects of dimethyl sulfoxide on humoral immune responses to acetylcholine receptors in the rat. ( Drachman, DB; Pestronk, A; Sims, C; Teoh, R, 1985)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Odierna, GL1
Phillips, WD1
Pestronk, A3
Drachman, DB3
Ashwood-Smith, MJ1
Teoh, R1
Sims, C1

Other Studies

5 other studies available for dimethyl sulfoxide and Myasthenia Gravis

ArticleYear
The Safety Factor for Neuromuscular Transmission: Effects of Dimethylsulphoxide, Cannabinoids and Synaptic Homeostasis.
    Journal of neuromuscular diseases, 2021, Volume: 8, Issue:5

    Topics: Action Potentials; Animals; Cannabinoids; Diaphragm; Dimethyl Sulfoxide; Homeostasis; Mice; Motor En

2021
Therapeutic strategies in experimental autoimmune myasthenia gravis.
    Annals of the New York Academy of Sciences, 1981, Volume: 377

    Topics: Animals; Antibodies; Autoimmune Diseases; Cyclophosphamide; Dimethyl Sulfoxide; Female; Myasthenia G

1981
DMSO and immunity.
    Nature, 1981, Apr-02, Volume: 290, Issue:5805

    Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Immunity; Mya

1981
Dimethyl sulphoxide reduces anti-receptor antibody titres in experimental myasthenia gravis.
    Nature, 1980, Dec-25, Volume: 288, Issue:5792

    Topics: Animals; Autoantibodies; Dimethyl Sulfoxide; Disease Models, Animal; Female; Myasthenia Gravis; Rats

1980
Effects of dimethyl sulfoxide on humoral immune responses to acetylcholine receptors in the rat.
    Clinical immunology and immunopathology, 1985, Volume: 37, Issue:2

    Topics: Animals; Antibody Formation; Autoimmune Diseases; Dimethyl Sulfoxide; Female; Immunization; Immuniza

1985