dimethyl sulfoxide has been researched along with Multiple Sclerosis in 5 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Myelin basic protein peptide 83-99 (MBP83-99) is the most immunodominant epitope playing a significant role in the multiple sclerosis (MS), an autoimmune disease of the central nervous system." | 7.76 | NMR structural elucidation of myelin basic protein epitope 83-99 implicated in multiple sclerosis. ( Deraos, G; Matsoukas, J; Spyranti, Z; Spyroulias, GA; Tselios, T, 2010) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Myelin basic protein peptide 83-99 (MBP83-99) is the most immunodominant epitope playing a significant role in the multiple sclerosis (MS), an autoimmune disease of the central nervous system." | 3.76 | NMR structural elucidation of myelin basic protein epitope 83-99 implicated in multiple sclerosis. ( Deraos, G; Matsoukas, J; Spyranti, Z; Spyroulias, GA; Tselios, T, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spyranti, Z | 1 |
| Tselios, T | 1 |
| Deraos, G | 1 |
| Matsoukas, J | 1 |
| Spyroulias, GA | 1 |
| Zingerman, LIa | 1 |
| Svistov, AS | 1 |
| Golovkin, VI | 1 |
| Zavirushchev, SP | 1 |
| Deber, CM | 1 |
| Hughes, DW | 1 |
| Fraser, PE | 1 |
| Pawagi, AB | 1 |
| Moscarello, MA | 1 |
1 review available for dimethyl sulfoxide and Multiple Sclerosis
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
1 trial available for dimethyl sulfoxide and Multiple Sclerosis
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
4 other studies available for dimethyl sulfoxide and Multiple Sclerosis
| Article | Year |
|---|---|
NMR structural elucidation of myelin basic protein epitope 83-99 implicated in multiple sclerosis.
Topics: Algorithms; Amino Acid Motifs; Amino Acid Sequence; Dimethyl Sulfoxide; Humans; Hydrogen Bonding; Im | 2010 |
[Dimexide (dimethylsulfoxide) in the treatment of multiple sclerosis].
Topics: Adrenal Cortex Hormones; Adult; Biological Products; Dimethyl Sulfoxide; Drug Combinations; Drug The | 1984 |
[A case of the successful dimethyl sulfoxide therapy of multiple sclerosis with trophic lesions and a cystostoma].
Topics: Adult; Chronic Disease; Combined Modality Therapy; Cystostomy; Dimethyl Sulfoxide; Disease Progressi | 1996 |
Binding of human normal and multiple sclerosis-derived myelin basic protein to phospholipid vesicles: effects on membrane head group and bilayer regions.
Topics: Chemical Phenomena; Chemistry; Dimethyl Sulfoxide; Humans; Lipid Bilayers; Magnetic Resonance Spectr | 1986 |