Page last updated: 2024-10-18

dimethyl sulfoxide and Methemoglobinemia

dimethyl sulfoxide has been researched along with Methemoglobinemia in 3 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" Carbon monoxide-oximetry may falsely identify sulfhemoglobin as methemoglobin; sulfhemoglobinemia should be considered in cases of methemoglobinemia refractory to methylene blue therapy."3.70Sulfhemoglobinemia after dermal application of DMSO. ( Burgess, JL; Hamner, AP; Robertson, WO, 1998)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burgess, JL1
Hamner, AP1
Robertson, WO1
DiStefano, V1
Klahn, JJ1
Lamb, TW1

Other Studies

3 other studies available for dimethyl sulfoxide and Methemoglobinemia

ArticleYear
Sulfhemoglobinemia after dermal application of DMSO.
    Veterinary and human toxicology, 1998, Volume: 40, Issue:2

    Topics: Administration, Topical; Adult; Anti-Infective Agents, Urinary; Anti-Inflammatory Agents; Carbon Mon

1998
Observations on the pharmacology and hemolytic activity of dimethyl sulfoxide.
    Toxicology and applied pharmacology, 1965, Volume: 7, Issue:5

    Topics: Animals; Atropine; Blood Chemical Analysis; Blood Pressure; Cats; Chromatography, Gas; Dimethyl Sulf

1965
Tissue gas tensions during methemoglobinemia.
    Journal of applied physiology, 1966, Volume: 21, Issue:3

    Topics: Animals; Blood Viscosity; Carbon Dioxide; Dimethyl Sulfoxide; Methemoglobinemia; Oxygen; Partial Pre

1966