dimethyl sulfoxide has been researched along with Malignant Melanoma in 36 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of B16-F10 melanoma cells with dimethylsulfoxide (DMSO) or butyric acid (BA) inhibits cell growth and delays tumor appearance in syngeneic mice." | 7.67 | Growth inhibition of murine melanoma by butyric acid and dimethylsulfoxide. ( Aloni, D; Beery, E; Malik, H; Nordenberg, J; Novogrodsky, A; Stenzel, KH; Wasserman, L, 1986) |
| "Using a panel of pharmacological inhibitors (BAY 43-9006, PD98059, U0126, wortmannin, LY294002) we inhibited the MAPK and AKT signalling pathways at different levels and evaluated the effects on growth, survival and invasion of melanoma cells in monolayer and organotypic skin culture." | 3.74 | Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment. ( Busch, S; Garbe, C; Herlyn, M; Kulms, D; Lasithiotakis, K; Maczey, E; Meier, F; Schittek, B, 2007) |
| " Treatment of human melanoma cells with recombinant fibroblast interferon (IFN-beta) and the protein kinase C activator mezerein (MEZ) results in an irreversible loss in growth potential, suppression of tumorigenic properties and induction of terminal cell differentiation." | 3.71 | Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties. ( Alexandre, D; Chada, S; Chen, Y; Christiansen, KA; Fisher, PB; Goldstein, NI; Gopalkrishnan, RV; Huang, EY; Huberman, E; Jiang, H; Kang, D; Lebedeva, IV; Leszczyniecka, M; Lin, JJ; Madireddi, MT; Mei, MX; Mhashilkar, AB; Pestka, S; Sivo, F; Su, Z; Vozhilla, N, 2001) |
| "Sodium butyrate (butyrate), 5-azacytidine (5Aza-C), dimethyl sulfoxide (DMSO), and dimethyl formamide (DMF) were applied to a human melanoma cell line for the purpose of inducing pigmentation and terminal differentiation." | 3.68 | In vitro phenotypic alteration of human melanoma cells induced by differentiating agents: heterogeneous effects on cellular growth and morphology, enzymatic activity, and antigenic expression. ( Parsons, PG; Takahashi, H, 1990) |
| "Treatment of B16-F10 melanoma cells with dimethylsulfoxide (DMSO) or butyric acid (BA) inhibits cell growth and delays tumor appearance in syngeneic mice." | 3.67 | Growth inhibition of murine melanoma by butyric acid and dimethylsulfoxide. ( Aloni, D; Beery, E; Malik, H; Nordenberg, J; Novogrodsky, A; Stenzel, KH; Wasserman, L, 1986) |
| "Melanoma is responsible for more than half of the deaths related to skin cancer in the last few decades." | 1.91 | Detection of melanin influence on skin samples based on Raman spectroscopy and optical coherence tomography dual-modal approach. ( Kukk, AF; Roth, B; Wu, D, 2023) |
| "Following trametinib treatment of melanoma cells, viability was reduced in both cutaneous (MEL888 26%, P < 0." | 1.91 | Direct early growth response-1 knockdown decreases melanoma viability independent of mitogen-activated extracellular signal-related kinase inhibition. ( Andrews-Pfannkoch, CM; Dalvin, LA; Erickson, SA; Fautsch, MP; Marmorstein, AD; Miley, DR; Pulido, JS; Vile, RG, 2023) |
| "Melanoma is a highly metastatic and lethal form of skin cancer." | 1.40 | BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling. ( Cook, M; Girotti, MR; Gore, M; Hayes, A; Larkin, J; Lorigan, P; Marais, R; Niculescu-Duvaz, D; Pedersen, M; Sanchez-Laorden, B; Saturno, G; Springer, C; Turajlic, S; Viros, A; Zambon, A, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (36.11) | 18.7374 |
| 1990's | 5 (13.89) | 18.2507 |
| 2000's | 7 (19.44) | 29.6817 |
| 2010's | 8 (22.22) | 24.3611 |
| 2020's | 3 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sulaiman, AAA | 1 |
| Sobeai, HMA | 1 |
| Aldawood, E | 1 |
| Abogosh, A | 1 |
| Alhazzani, K | 1 |
| Alotaibi, MR | 1 |
| Ahmad, S | 1 |
| Alhoshani, A | 1 |
| Isab, AA | 1 |
| Wu, D | 1 |
| Kukk, AF | 1 |
| Roth, B | 1 |
| Miley, DR | 1 |
| Andrews-Pfannkoch, CM | 1 |
| Pulido, JS | 1 |
| Erickson, SA | 1 |
| Vile, RG | 1 |
| Fautsch, MP | 1 |
| Marmorstein, AD | 1 |
| Dalvin, LA | 1 |
| Vilgelm, AE | 1 |
| Saleh, N | 1 |
| Shattuck-Brandt, R | 1 |
| Riemenschneider, K | 1 |
| Slesur, L | 1 |
| Chen, SC | 1 |
| Johnson, CA | 1 |
| Yang, J | 1 |
| Blevins, A | 1 |
| Yan, C | 1 |
| Johnson, DB | 1 |
| Al-Rohil, RN | 1 |
| Halilovic, E | 1 |
| Kauffmann, RM | 1 |
| Kelley, M | 1 |
| Ayers, GD | 1 |
| Richmond, A | 1 |
| Ferk, P | 1 |
| Dariš, B | 1 |
| Tapia, IJ | 1 |
| Aris, M | 1 |
| Arriaga, JM | 1 |
| Blanco, PA | 1 |
| Mazzobre, F | 1 |
| Vega, J | 1 |
| Mordoh, J | 1 |
| Barrio, MM | 1 |
| Sanchez-Laorden, B | 1 |
| Viros, A | 1 |
| Girotti, MR | 1 |
| Pedersen, M | 1 |
| Saturno, G | 1 |
| Zambon, A | 1 |
| Niculescu-Duvaz, D | 1 |
| Turajlic, S | 1 |
| Hayes, A | 1 |
| Gore, M | 1 |
| Larkin, J | 1 |
| Lorigan, P | 1 |
| Cook, M | 1 |
| Springer, C | 1 |
| Marais, R | 1 |
| Singh, A | 2 |
| Sand, JM | 1 |
| Bauer, SJ | 1 |
| Hafeez, BB | 1 |
| Meske, L | 1 |
| Verma, AK | 1 |
| Tay, KH | 1 |
| Liu, X | 1 |
| Chi, M | 1 |
| Jin, L | 1 |
| Jiang, CC | 1 |
| Guo, ST | 1 |
| Verrills, NM | 1 |
| Tseng, HY | 1 |
| Zhang, XD | 1 |
| Caron, JM | 2 |
| Elisia, I | 1 |
| Nakamura, H | 1 |
| Lam, V | 1 |
| Hofs, E | 1 |
| Cederberg, R | 1 |
| Cait, J | 1 |
| Hughes, MR | 1 |
| Lee, L | 1 |
| Jia, W | 1 |
| Adomat, HH | 1 |
| Guns, ES | 1 |
| McNagny, KM | 1 |
| Samudio, I | 1 |
| Krystal, G | 1 |
| Casolaro, M | 1 |
| Cini, R | 1 |
| Del Bello, B | 1 |
| Ferrali, M | 1 |
| Maellaro, E | 1 |
| Munshi, A | 1 |
| Kurland, JF | 1 |
| Nishikawa, T | 1 |
| Chiao, PJ | 1 |
| Andreeff, M | 1 |
| Meyn, RE | 1 |
| Brindell, M | 1 |
| Kuliś, E | 1 |
| Elmroth, SK | 1 |
| Urbańska, K | 1 |
| Stochel, G | 1 |
| Meier, F | 1 |
| Busch, S | 1 |
| Lasithiotakis, K | 1 |
| Kulms, D | 1 |
| Garbe, C | 1 |
| Maczey, E | 1 |
| Herlyn, M | 1 |
| Schittek, B | 1 |
| Oppermann, M | 1 |
| Fechner, H | 1 |
| Eberle, J | 1 |
| Luchs, A | 1 |
| Sumida, DH | 1 |
| Visconti, MA | 1 |
| Castrucci, AM | 1 |
| Manna, A | 1 |
| Talevi, N | 1 |
| Manna, M | 1 |
| Porcellini, A | 1 |
| Lucarelli, G | 1 |
| Borovanský, J | 2 |
| Riley, PA | 1 |
| Tveit, KM | 1 |
| Fodstad, O | 1 |
| Johannessen, JV | 1 |
| Olsnes, S | 1 |
| Sturm, RA | 2 |
| O'Sullivan, BJ | 1 |
| Thomson, JA | 1 |
| Jamshidi, N | 1 |
| Pedley, J | 1 |
| Parsons, PG | 3 |
| Lopes, NM | 1 |
| Miller, HP | 1 |
| Young, ND | 1 |
| Bhuyan, BK | 1 |
| Huang, EY | 1 |
| Madireddi, MT | 1 |
| Gopalkrishnan, RV | 1 |
| Leszczyniecka, M | 1 |
| Su, Z | 1 |
| Lebedeva, IV | 1 |
| Kang, D | 1 |
| Jiang, H | 1 |
| Lin, JJ | 1 |
| Alexandre, D | 1 |
| Chen, Y | 1 |
| Vozhilla, N | 1 |
| Mei, MX | 1 |
| Christiansen, KA | 1 |
| Sivo, F | 1 |
| Goldstein, NI | 1 |
| Mhashilkar, AB | 1 |
| Chada, S | 1 |
| Huberman, E | 2 |
| Pestka, S | 1 |
| Fisher, PB | 2 |
| Heckman, C | 1 |
| Langenbach, R | 1 |
| Scherbel, VG | 1 |
| Weidemann, G | 1 |
| Takahashi, H | 2 |
| Bisshop, F | 1 |
| Tarasiuk, A | 1 |
| Grant, S | 1 |
| Nordenberg, J | 1 |
| Wasserman, L | 1 |
| Beery, E | 1 |
| Aloni, D | 1 |
| Malik, H | 1 |
| Stenzel, KH | 1 |
| Novogrodsky, A | 1 |
| Pályi, I | 1 |
| Yan, YS | 1 |
| Stanley, WS | 1 |
| Trimpe, KL | 1 |
| Zwilling, BS | 1 |
| Levine, N | 1 |
| Siracký, J | 1 |
| Blasko, M | 1 |
| Wood, DC | 1 |
| Varela, VL | 1 |
1 review available for dimethyl sulfoxide and Malignant Melanoma
| Article | Year |
|---|---|
Effects of interferon on differentiation of normal and tumor cells.
Topics: Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Dimethyl Sulfoxide; Hematopoiesis; H | 1985 |
35 other studies available for dimethyl sulfoxide and Malignant Melanoma
| Article | Year |
|---|---|
In vitro and in vivo antitumor studies of potential anticancer agents of platinum(II) complexes of dicyclopentadiene and dithiocarbamates§.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cisplatin; Coordination Complexes; Dime | 2022 |
Detection of melanin influence on skin samples based on Raman spectroscopy and optical coherence tomography dual-modal approach.
Topics: Dimethyl Sulfoxide; Humans; Melanins; Melanoma; Skin Neoplasms; Spectrum Analysis, Raman; Tomography | 2023 |
Direct early growth response-1 knockdown decreases melanoma viability independent of mitogen-activated extracellular signal-related kinase inhibition.
Topics: Cell Line, Tumor; Dimethyl Sulfoxide; Extracellular Signal-Regulated MAP Kinases; Humans; Melanoma; | 2023 |
MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21.
Topics: Analysis of Variance; Animals; Blotting, Western; Cell Cycle; Cell Survival; Cyclin-Dependent Kinase | 2019 |
The influence of dimethyl sulfoxide (DMSO) on metabolic activity and morphology of melanoma cell line WM-266-4.
Topics: Cell Line, Tumor; Cell Survival; Dimethyl Sulfoxide; Humans; Melanoma; Microscopy, Phase-Contrast | 2018 |
Development of a novel methodology for cryopreservation of melanoma cells applied to CSF470 therapeutic vaccine.
Topics: Cancer Vaccines; Cell Line, Tumor; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Free | 2013 |
BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling.
Topics: Animals; Blotting, Western; Cell Shape; Dimethyl Sulfoxide; Drug Resistance, Neoplasm; Enzyme-Linked | 2014 |
Topically applied Hsp90 inhibitor 17AAG inhibits UVR-induced cutaneous squamous cell carcinomas.
Topics: Acetone; Animals; Benzoquinones; Dimethyl Sulfoxide; Epidermis; HSP90 Heat-Shock Proteins; Humans; I | 2015 |
Involvement of vacuolar H(+)-ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720.
Topics: Adenosine Triphosphate; Autophagy; Cell Death; Cell Line, Tumor; Cell Membrane; Dimethyl Sulfoxide; | 2015 |
Methyl Sulfone Blocked Multiple Hypoxia- and Non-Hypoxia-Induced Metastatic Targets in Breast Cancer Cells and Melanoma Cells.
Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Child, Preschool; Dimethyl Sulfoxide; Female; Humans; Iron; | 2015 |
DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis.
Topics: Animals; Arthritis; Blood Cells; Cell Differentiation; Cell Line, Tumor; Cell Survival; Chemokines; | 2016 |
Cisplatin/hydrogel complex in cancer therapy.
Topics: Acrylamides; Antineoplastic Agents; Cisplatin; Delayed-Action Preparations; Dimethyl Sulfoxide; Drug | 2009 |
Inhibition of constitutively activated nuclear factor-kappaB radiosensitizes human melanoma cells.
Topics: Benzamides; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Line, T | 2004 |
Light-induced anticancer activity of [RuCl2(DMSO)4] complexes.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dimethyl Sul | 2005 |
Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment.
Topics: Androstadienes; Apoptosis; Benzenesulfonates; Blotting, Western; Cell Line, Tumor; Cell Proliferatio | 2007 |
Dimethyl sulfoxide enhances doxycycline-dependent protein expression in Tet-On cells.
Topics: Apoptosis; Biotechnology; Cell Line, Tumor; Dimethyl Sulfoxide; DNA Fragmentation; Doxycycline; Esch | 2007 |
Biological effects of insulin on murine melanoma cells and fish erythrophoroma cells: a comparative study.
Topics: Animals; Autoradiography; Blotting, Western; Cell Differentiation; Cell Division; Cell Line, Tumor; | 2008 |
[The use of autologous bone marrow transplants in malignant hemopathies and solid tumors].
Topics: Bone Marrow Transplantation; Carcinoma; Colony-Forming Units Assay; Dimethyl Sulfoxide; Freezing; Hu | 1981 |
The effect of divalent cations on Cloudman melanoma cells.
Topics: Animals; Cadmium; Cations, Divalent; Cell Count; Cell Division; Cell Line; Copper; Dimethyl Sulfoxid | 1983 |
A human melanoma cell line established from xenograft in athymic mice.
Topics: Animals; Cell Division; Cell Line; Dimethyl Sulfoxide; Humans; Isoenzymes; Karyotyping; Melanins; Me | 1980 |
Expression studies of pigmentation and POU-domain genes in human melanoma cells.
Topics: Acetamides; Base Sequence; Binding Sites; Dimethyl Sulfoxide; DNA; DNA-Binding Proteins; Gene Expres | 1994 |
Assessment of microtubule stabilizers by semiautomated in vitro microtubule protein polymerization and mitotic block assays.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Assay; Cattle; Cells, Cultured; Di | 1997 |
Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.
Topics: Antigens, Neoplasm; Apoptosis; Base Sequence; Carcinoma; Cell Differentiation; Cell Division; Chromo | 2001 |
Stimulation of differentiated functions in human melanoma cells by tumor-promoting agents and dimethyl sulfoxide.
Topics: Cell Differentiation; Cell Division; Cells, Cultured; Dimethyl Sulfoxide; Dose-Response Relationship | 1979 |
[New method for intranodular administration of 2,4-dinitro-1-chlorobenzene].
Topics: Adjuvants, Pharmaceutic; Dimethyl Sulfoxide; Dinitrochlorobenzene; Immunotherapy; Injections; Melano | 1975 |
In vitro phenotypic alteration of human melanoma cells induced by differentiating agents: heterogeneous effects on cellular growth and morphology, enzymatic activity, and antigenic expression.
Topics: Antigens, Neoplasm; Azacitidine; Butyrates; Butyric Acid; Cell Cycle; Cell Differentiation; Cell Div | 1990 |
A melanoma octamer binding protein is responsive to differentiating agents.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Line, Transformed; Dimethyl Sulfoxide; Dithiothr | 1991 |
Sensitivity of human melanoma cells in vitro to retinoic acid incorporated in liposomes.
Topics: Cell Division; Dimethyl Sulfoxide; Drug Carriers; Humans; Liposomes; Melanoma; Tretinoin; Tumor Cell | 1991 |
Growth inhibition of murine melanoma by butyric acid and dimethylsulfoxide.
Topics: Animals; Butyrates; Butyric Acid; Cell Division; Cell Line; Cell Survival; Dimethyl Sulfoxide; Melan | 1986 |
Heterogeneity of the response to inducers of differentiation and to cytostatics of tumor cell populations.
Topics: Antineoplastic Agents; Cell Differentiation; Cisplatin; Cytarabine; Dacarbazine; Dimethyl Sulfoxide; | 1988 |
Effect of differentiating agents on nucleolar organizer region activity in human melanoma cells.
Topics: Animals; Cell Differentiation; Dimethyl Sulfoxide; Humans; Karyotyping; Melanoma; Mice; Mice, Nude; | 1988 |
Modulation of B16 melanoma antigen expression by lymphokines and dimethyl sulfoxide.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Cell Line; Dimethyl Sulfoxid | 1986 |
Effects of topical retinoic acid on intracutaneously implanted S91 melanoma in mice.
Topics: Administration, Topical; Animals; Carbon Radioisotopes; Dimethyl Sulfoxide; Dose-Response Relationsh | 1985 |
Stimulation of differentiation in human melanoma cells by dimethyl sulphoxide (DMSO).
Topics: Cell Cycle; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Melanins; Melanoma | 1985 |
Hematoxylin-DMSO mixture as an anti-tumor agent in mice.
Topics: Animals; Antineoplastic Agents; Benzopyrans; Carcinoma; Dimethyl Sulfoxide; Drug Stability; Leukemia | 1972 |