dimethyl sulfoxide has been researched along with Malaria in 6 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mefloquine (Mef), a poorly soluble and highly bitter drug, has been used for malaria prophylaxis and treatment." | 3.85 | Development of a Rapidly Dissolvable Oral Pediatric Formulation for Mefloquine Using Liposomes. ( Chen, WC; Diako, C; Li, SD; Ross, CF; Tang, WH; Tang, WL, 2017) |
| "Thionine O was a partial (hyperbolic) uncompetitive inhibitor with Ki and alpha values of 0." | 1.30 | Inhibitors of glutathione reductase as potential antimalarial drugs. Kinetic cooperativity and effect of dimethyl sulphoxide on inhibition kinetics. ( Dascombe, MJ; Douglas, KT; Lüönd, RM; McKie, JH; Vale, J, 1998) |
| " The impressive antimalarial activity of Taxol, at a dosage that has been tolerated in humans, establishes its potential utility for treatment of severe, drug-resistant human malaria." | 1.29 | Taxol arrests the development of blood-stage Plasmodium falciparum in vitro and Plasmodium chabaudi adami in malaria-infected mice. ( Farley, PJ; Long, CA; Pouvelle, B; Taraschi, TF, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, WL | 1 |
| Tang, WH | 1 |
| Chen, WC | 1 |
| Diako, C | 1 |
| Ross, CF | 1 |
| Li, SD | 1 |
| Özbılgın, A | 1 |
| Östan, İ | 1 |
| Tabak, T | 1 |
| Aşar, K | 1 |
| COLLINS, WE | 1 |
| JEFFERY, GM | 1 |
| Nakornchai, S | 1 |
| Satarug, S | 1 |
| Potiwan, C | 1 |
| Yuthavong, Y | 1 |
| Pouvelle, B | 1 |
| Farley, PJ | 1 |
| Long, CA | 1 |
| Taraschi, TF | 1 |
| Lüönd, RM | 1 |
| McKie, JH | 1 |
| Douglas, KT | 1 |
| Dascombe, MJ | 1 |
| Vale, J | 1 |
6 other studies available for dimethyl sulfoxide and Malaria
| Article | Year |
|---|---|
Development of a Rapidly Dissolvable Oral Pediatric Formulation for Mefloquine Using Liposomes.
Topics: Administration, Oral; Animals; Dimethyl Sulfoxide; Drug Delivery Systems; Female; Liposomes; Malaria | 2017 |
[Cryopreservation of plasmodia with malaria models and establishment of a cryobank].
Topics: Animals; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Disease Models, Animal; Erythr | 2010 |
The use of dimethyl sulfoxide in the low-temperature frozen preservation of experimental malarias.
Topics: Cold Temperature; Dimethyl Sulfoxide; Freezing; Malaria; Plasmodium; Preservation, Biological; Sulfu | 1963 |
Enhanced fusion capacity of malaria (Plasmodium berghei)-infected mouse red cells.
Topics: Animals; Calcium; Cell Fusion; Dimethyl Sulfoxide; Erythrocyte Membrane; Erythrocytes; In Vitro Tech | 1980 |
Taxol arrests the development of blood-stage Plasmodium falciparum in vitro and Plasmodium chabaudi adami in malaria-infected mice.
Topics: Animals; Dimethyl Sulfoxide; Erythrocytes; Humans; Malaria; Male; Mice; Mice, Inbred BALB C; Paclita | 1994 |
Inhibitors of glutathione reductase as potential antimalarial drugs. Kinetic cooperativity and effect of dimethyl sulphoxide on inhibition kinetics.
Topics: Animals; Antimalarials; Dimethyl Sulfoxide; Glutathione Reductase; Malaria; Mice; Oxazines; Phenazin | 1998 |