dimethyl sulfoxide has been researched along with Lung Neoplasms in 68 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether thalidomide inhibits the growth of primary and pulmonary metastatic canine osteosarcoma in mice after xenotransplantation." | 7.72 | Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice. ( Baldwin, JM; Detrisac, CJ; Farese, JP; Fox, LE; Roberts, SL; Van Gilder, JM, 2004) |
| "The effects of Na[trans-RuCl4(DMSO)Im] (NAMI), Na[trans-RuCl4(TMSO) Ind] (TIND) and Na[trans-RuCl4(TMSO)Iq] TEQU) were tested in vitro on TLX5 lymphoma cells in comparison to cisplatin by means of the sulforhodamine-B test SRB) for protein content determination, by acridine orange and propidium iodide staining and by means of the bromodeoxyuridine test, for cell cycle modifications." | 7.70 | Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry. ( Bergamo, A; Capozzi, I; Clerici, K; Cocchietto, M; Salerno, G; Sava, G, 1998) |
| "Dimethyl sulfoxide (DMSO) has previously been shown to increase the surface expression of H-2K and H-2D antigens on cultured line 1 carcinoma cells." | 7.67 | Enhanced immune recognition of H-2 antigen-deficient murine lung carcinoma cells following treatment with dimethyl sulfoxide. ( Bahler, DW; Lord, EM, 1985) |
| " We found that polar compounds and butyric acid, which are known to alter the expressions of normally silent genes, enhanced the lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells." | 4.77 | Modification of the metastatic potential of tumor cells by drugs. ( Takenaga, K, 1986) |
| "Imidazolium-trans-dimethylsulfoxideimidazoletetrachlororuthenate (NAMI-A) is a ruthenium compound effective on solid tumor metastases." | 3.72 | Primary tumor, lung and kidney retention and antimetastasis effect of NAMI-A following different routes of administration. ( Cocchietto, M; Sava, G; Sorc, A; Zorzet, S, 2003) |
| "To determine whether thalidomide inhibits the growth of primary and pulmonary metastatic canine osteosarcoma in mice after xenotransplantation." | 3.72 | Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice. ( Baldwin, JM; Detrisac, CJ; Farese, JP; Fox, LE; Roberts, SL; Van Gilder, JM, 2004) |
| "The effects of Na[trans-RuCl4(DMSO)Im] (NAMI), Na[trans-RuCl4(TMSO) Ind] (TIND) and Na[trans-RuCl4(TMSO)Iq] TEQU) were tested in vitro on TLX5 lymphoma cells in comparison to cisplatin by means of the sulforhodamine-B test SRB) for protein content determination, by acridine orange and propidium iodide staining and by means of the bromodeoxyuridine test, for cell cycle modifications." | 3.70 | Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry. ( Bergamo, A; Capozzi, I; Clerici, K; Cocchietto, M; Salerno, G; Sava, G, 1998) |
| "A low concentration of differentiation inducers such as dimethylsulphoxide (DMSO), sodium butyrate, hexamethylene bisacetamide and sodium phenylacetate greatly enhanced the antiproliferative effect in vitro and in vivo of interferon alpha (IFN-alpha) to several human lung adenocarcinoma cells." | 3.69 | Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents. ( Goto, I; Honma, Y; Yamamoto-Yamaguchi, Y, 1996) |
| "Dimethyl sulfoxide (DMSO) has previously been shown to increase the surface expression of H-2K and H-2D antigens on cultured line 1 carcinoma cells." | 3.67 | Enhanced immune recognition of H-2 antigen-deficient murine lung carcinoma cells following treatment with dimethyl sulfoxide. ( Bahler, DW; Lord, EM, 1985) |
| "Lung cancer is the second most common cancer in both men and women and thus a leading cause of cancer-related deaths worldwide." | 2.53 | Current State of Metal-Based Drugs for the Efficient Therapy of Lung Cancers and Lung Metastases. ( Biersack, B; Schobert, R, 2016) |
| "Dimethyl sulfoxide (DMSO) is an amphipathic molecule that displays a diversity of antitumor activities." | 1.38 | Dimethyl sulfoxide promotes the multiple functions of the tumor suppressor HLJ1 through activator protein-1 activation in NSCLC cells. ( Chen, JJ; Hsu, YL; Lai, YH; Lin, SY; Liu, YJ; Wang, CC, 2012) |
| "Incident lung (n = 665) and colorectal cancers (n = 428) were obtained from the Surveillance, Epidemiology, and End Results cancer registry." | 1.35 | Associations of herbal and specialty supplements with lung and colorectal cancer risk in the VITamins and Lifestyle study. ( Galanko, JA; Littman, A; Satia, JA; Slatore, CG; White, E, 2009) |
| " The SCLC cell lines, NCI-H69, NCI-H146 and NCI-H209, showed a dose-response (tested between 0." | 1.31 | Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571. ( Griffin, JD; Healy, ME; Johnson, BE; Lin, J; Maulik, G; Salgia, R; Sattler, M; Stiles, CD; Verma, S; Wang, WL, 2000) |
| " These data indicated that NAMI-A is well absorbed after oral administration although there is no connection between lung concentration and the antimetastatic activity." | 1.30 | Comparison of the effects of the antimetastatic compound ImH[trans-RuCl4(DMSO)Im] (NAMI-A) on the arthritic rat and on MCa mammary carcinoma in mice. ( Alessio, E; Capozzi, I; Clerici, K; Cocchietto, M; Gagliardi, R; Marrella, M; Mestroni, G; Milanino, R; Sava, G, 1998) |
| " Cisplatin reduced body weight gain and spleen weight during treatment and was much more toxic than NAMI-A on liver sinusoids, kidney tubules, and lung epithelium." | 1.30 | In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin. ( Alessio, E; Bergamo, A; Furlani, A; Gagliardi, R; Mestroni, G; Sava, G; Scarcia, V, 1999) |
| " Liver tumors (nodular hyperplasia) appeared only in FA-treated males but no dose-response relationship was evident." | 1.29 | Induction of lung and liver tumors by fluoranthene in a preweanling CD-1 mouse bioassay. ( Busby, WF; Wang, JS, 1993) |
| "The line 1 lung carcinoma is a spontaneous murine tumor deficient in class I antigen expression." | 1.28 | Alteration of the metastatic potential of line 1 lung carcinoma cells: opposite effects of class I antigen induction by interferons versus DMSO or gene transfection. ( Blieden, TM; Cerosaletti, KM; Frelinger, JG; Harwell, LW; Lord, EM; Welsh, KM, 1990) |
| "Dimethyl sulfoxide-treated P-29 cells were trapped in the lung more than untreated cells and were cleared from the lungs more slowly than untreated cells." | 1.27 | Enhanced metastatic potential of cloned low-metastatic Lewis lung carcinoma cells treated in vitro with dimethyl sulfoxide. ( Takenaga, K, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (27.94) | 18.7374 |
| 1990's | 22 (32.35) | 18.2507 |
| 2000's | 13 (19.12) | 29.6817 |
| 2010's | 12 (17.65) | 24.3611 |
| 2020's | 2 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, P | 1 |
| Ni, C | 1 |
| Teng, P | 1 |
| Malviya, N | 1 |
| Sonkar, C | 1 |
| Ganguly, R | 1 |
| Bhattacherjee, D | 1 |
| Bhabak, KP | 1 |
| Mukhopadhyay, S | 1 |
| Kim, DH | 1 |
| Sp, N | 1 |
| Kang, DY | 1 |
| Jo, ES | 1 |
| Rugamba, A | 1 |
| Jang, KJ | 1 |
| Yang, YM | 1 |
| Ji, KX | 1 |
| Cui, F | 1 |
| Qu, D | 1 |
| Sun, RY | 1 |
| Sun, P | 1 |
| Chen, FY | 1 |
| Wang, SL | 1 |
| Sun, HS | 1 |
| Ponnapakkam, T | 1 |
| Saulsberry, T | 1 |
| Hill, T | 1 |
| Hill-Odom, M | 1 |
| Goyal, N | 1 |
| Anbalagan, M | 1 |
| Liu, J | 1 |
| Foroozesh, M | 1 |
| Hammoudeh, SM | 1 |
| Hammoudeh, AM | 1 |
| Hamoudi, R | 1 |
| Bailey, TL | 1 |
| Stubbs, C | 1 |
| Murray, K | 1 |
| Tomás, RMF | 1 |
| Otten, L | 1 |
| Gibson, MI | 1 |
| Obradovic, J | 2 |
| Jurisic, V | 2 |
| Tosic, N | 2 |
| Mrdjanovic, J | 1 |
| Perin, B | 1 |
| Pavlovic, S | 2 |
| Djordjevic, N | 2 |
| Bergamo, A | 10 |
| Riedel, T | 1 |
| Dyson, PJ | 2 |
| Sava, G | 20 |
| Leijen, S | 1 |
| Burgers, SA | 1 |
| Baas, P | 1 |
| Pluim, D | 1 |
| Tibben, M | 1 |
| van Werkhoven, E | 1 |
| Alessio, E | 13 |
| Beijnen, JH | 1 |
| Schellens, JH | 1 |
| Biersack, B | 1 |
| Schobert, R | 1 |
| Kurimoto, R | 1 |
| Iwasawa, S | 1 |
| Ebata, T | 1 |
| Ishiwata, T | 1 |
| Sekine, I | 1 |
| Tada, Y | 1 |
| Tatsumi, K | 1 |
| Koide, S | 1 |
| Iwama, A | 1 |
| Takiguchi, Y | 1 |
| Kulić, M | 1 |
| Satia, JA | 1 |
| Littman, A | 1 |
| Slatore, CG | 1 |
| Galanko, JA | 1 |
| White, E | 1 |
| Wang, CC | 1 |
| Lin, SY | 1 |
| Lai, YH | 1 |
| Liu, YJ | 1 |
| Hsu, YL | 1 |
| Chen, JJ | 1 |
| Gava, B | 4 |
| Mestroni, G | 11 |
| Serli, B | 3 |
| Cocchietto, M | 12 |
| Zorzet, S | 7 |
| Turrin, C | 2 |
| Vita, F | 1 |
| Soranzo, M | 1 |
| Zabucchi, G | 1 |
| DiGiovine, S | 1 |
| Pezzoni, G | 1 |
| Sartor, L | 1 |
| Garbisa, S | 2 |
| Sorc, A | 1 |
| Stocco, G | 1 |
| Casarsa, C | 2 |
| Pacor, S | 4 |
| Bacac, M | 1 |
| Vadori, M | 1 |
| Castellarin, A | 1 |
| Farese, JP | 1 |
| Fox, LE | 1 |
| Detrisac, CJ | 1 |
| Van Gilder, JM | 1 |
| Roberts, SL | 1 |
| Baldwin, JM | 1 |
| Zhang, B | 1 |
| Senator, D | 1 |
| Wilson, CJ | 1 |
| Ng, SC | 1 |
| Spessotto, P | 1 |
| Yokota, H | 1 |
| Guo, J | 1 |
| Matoba, M | 1 |
| Higashi, K | 1 |
| Tonami, H | 1 |
| Nagao, Y | 1 |
| Khalaila, I | 1 |
| Bussy, F | 1 |
| Takenaga, K | 5 |
| Fuks, JZ | 1 |
| Egorin, MJ | 1 |
| Aisner, J | 1 |
| Ostrow, SS | 1 |
| Klein, ME | 1 |
| Bachur, NR | 1 |
| Colvin, M | 1 |
| Wiernik, PH | 1 |
| Sarkisian, IuKh | 1 |
| Kir'ianov, IIu | 1 |
| Zhakova, LA | 1 |
| Silaeva, VA | 1 |
| Il'in, VI | 1 |
| Gagliardi, R | 5 |
| Wang, JS | 1 |
| Busby, WF | 1 |
| Sarriá, B | 1 |
| Naline, E | 1 |
| Cortijo, J | 1 |
| Moreau, J | 1 |
| Cerdá, JM | 1 |
| Morcillo, EJ | 1 |
| Advenier, C | 1 |
| Goto, I | 1 |
| Yamamoto-Yamaguchi, Y | 1 |
| Honma, Y | 1 |
| Capozzi, I | 6 |
| Masiero, L | 1 |
| Onisto, M | 1 |
| Nakae, T | 1 |
| Horai, T | 1 |
| Imamura, F | 1 |
| Akedo, H | 1 |
| Higashino, K | 1 |
| Clerici, K | 4 |
| Marrella, M | 1 |
| Milanino, R | 1 |
| Mastronarde, JG | 1 |
| Monick, MM | 1 |
| Mukaida, N | 1 |
| Matsushima, K | 1 |
| Hunninghake, GW | 1 |
| Gagliardi, G | 1 |
| Salerno, G | 1 |
| Scarcia, V | 2 |
| Furlani, A | 2 |
| Perbellini, A | 1 |
| Driscoll, B | 1 |
| Buckley, S | 1 |
| Barsky, L | 1 |
| Weinberg, K | 1 |
| Anderson, KD | 1 |
| Warburton, D | 1 |
| Wang, WL | 1 |
| Healy, ME | 1 |
| Sattler, M | 1 |
| Verma, S | 1 |
| Lin, J | 1 |
| Maulik, G | 1 |
| Stiles, CD | 1 |
| Griffin, JD | 1 |
| Johnson, BE | 1 |
| Salgia, R | 1 |
| Iengo, E | 1 |
| Tralka, TS | 1 |
| Rabson, AS | 1 |
| Giaccone, G | 1 |
| Broers, J | 1 |
| Jensen, S | 1 |
| Fridman, RI | 1 |
| Linnoila, R | 1 |
| Gazdar, AF | 1 |
| Davaris, P | 1 |
| Fytiza, R | 1 |
| Androulakakis, P | 1 |
| Papacharalampous, N | 1 |
| Cerosaletti, KM | 3 |
| Blieden, TM | 2 |
| Harwell, LW | 1 |
| Welsh, KM | 1 |
| Frelinger, JG | 4 |
| Lord, EM | 6 |
| Woodward, JG | 1 |
| McAdam, AJ | 1 |
| Bhide, SV | 1 |
| Ammigan, N | 1 |
| Nair, UJ | 1 |
| Lalitha, VS | 1 |
| Bahler, DW | 3 |
| Ranney, DF | 1 |
| Munker, M | 1 |
| Munker, R | 1 |
| Saxton, RE | 1 |
| Koeffler, HP | 1 |
| Nakamura, Y | 1 |
| Sakiyama, S | 1 |
| Roth, JA | 1 |
| Ames, RS | 1 |
| Fry, K | 1 |
| Lee, HM | 1 |
| Scannon, PJ | 1 |
| Lazenby, CM | 1 |
| Gescher, A | 1 |
| Dale, IL | 1 |
| Young, MR | 1 |
| Duffie, GP | 1 |
| Newby, M | 1 |
| Stoner, GD | 1 |
| Conran, PB | 1 |
| Greisiger, EA | 1 |
| Stober, J | 1 |
| Morgan, M | 1 |
| Pereira, MA | 1 |
| Sander, J | 1 |
| Bürkle, G | 1 |
| Bürkle, V | 1 |
| Gargus, JL | 1 |
| Paynter, OE | 1 |
| Reese, WH | 1 |
2 reviews available for dimethyl sulfoxide and Lung Neoplasms
| Article | Year |
|---|---|
Current State of Metal-Based Drugs for the Efficient Therapy of Lung Cancers and Lung Metastases.
Topics: Cisplatin; Dimethyl Sulfoxide; Ferrous Compounds; Humans; Lung Neoplasms; Metallocenes; Metalloporph | 2016 |
Modification of the metastatic potential of tumor cells by drugs.
Topics: Animals; Azacitidine; Butyrates; Butyric Acid; Carcinoma; Cell Division; Cell Line; Cells, Cultured; | 1986 |
1 trial available for dimethyl sulfoxide and Lung Neoplasms
| Article | Year |
|---|---|
Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycy | 2015 |
65 other studies available for dimethyl sulfoxide and Lung Neoplasms
| Article | Year |
|---|---|
Effects of artesunate on the malignant biological behaviors of non-small cell lung cancer in human and its mechanism.
Topics: A549 Cells; Apoptosis; Artesunate; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; | 2022 |
Novel Approach to Generate a Self-Deliverable Ru(II)-Based Anticancer Agent in the Self-Reacting Confined Gel Space.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Proliferation; Coordination Complexes; Dimethyl S | 2019 |
Effect of Methylsulfonylmethane on Proliferation and Apoptosis of A549 Lung Cancer Cells Through G
Topics: A549 Cells; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; | 2020 |
MiR-378 promotes the cell proliferation of non-small cell lung cancer by inhibiting FOXG1.
Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dimethyl Sulfoxide | 2018 |
Inhibition of breast tumor growth in mice after treatment with ceramide analog 315.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Ceramides; Dimethyl Sulfoxide; F | 2018 |
High-throughput quantification of the effect of DMSO on the viability of lung and breast cancer cells using an easy-to-use spectrophotometric trypan blue-based assay.
Topics: A549 Cells; Breast Neoplasms; Cell Survival; Dimethyl Sulfoxide; Humans; Lung Neoplasms; Spectrophot | 2019 |
Synthetically Scalable Poly(ampholyte) Which Dramatically Enhances Cellular Cryopreservation.
Topics: Cell Membrane; Cell Survival; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Humans; L | 2019 |
Optimization of PCR conditions for amplification of GC-Rich EGFR promoter sequence.
Topics: Base Composition; Dimethyl Sulfoxide; DNA; Genes, erbB-1; Genotyping Techniques; Humans; Lung Neopla | 2013 |
Preclinical combination therapy of the investigational drug NAMI-A(+) with doxorubicin for mammary cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Dimethyl Sulfoxide; Doxorubi | 2015 |
Drug resistance originating from a TGF-β/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; B7-H1 Antigen; Cell Line, Tumor; Cell | 2016 |
Effects of DMSO, glycerol, betaine and their combinations in detecting single nucleotide polymorphisms of epidermal growth factor receptor (EGFR) gene promoter sequence in non-small-cell lung cancer (NSCLC) patients.
Topics: Adult; Aged; Betaine; Carcinoma, Non-Small-Cell Lung; Dimethyl Sulfoxide; DNA, Neoplasm; Electrophor | 2016 |
Associations of herbal and specialty supplements with lung and colorectal cancer risk in the VITamins and Lifestyle study.
Topics: Aged; Chondroitin; Colorectal Neoplasms; Dietary Supplements; Dimethyl Sulfoxide; Female; Fish Oils; | 2009 |
Dimethyl sulfoxide promotes the multiple functions of the tumor suppressor HLJ1 through activator protein-1 activation in NSCLC cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell | 2012 |
Ruthenium-based NAMI-A type complexes with in vivo selective metastasis reduction and in vitro invasion inhibition unrelated to cell cytotoxicity.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Dimethyl Sulfoxide; G2 Phase; Humans; Lung Ne | 2002 |
Dual Action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cell Adhesion; Cell Division; | 2003 |
Primary tumor, lung and kidney retention and antimetastasis effect of NAMI-A following different routes of administration.
Topics: Administration, Inhalation; Administration, Oral; Aerosols; Animals; Antineoplastic Agents; Carcinom | 2003 |
Reduction of in vivo lung metastases by dinuclear ruthenium complexes is coupled to inhibition of in vitro tumour invasion.
Topics: Animals; Cell Line, Tumor; Collagen; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Comb | 2004 |
Intratumoral NAMI-A treatment triggers metastasis reduction, which correlates to CD44 regulation and tumor infiltrating lymphocyte recruitment.
Topics: Animals; Dimethyl Sulfoxide; Female; Hyaluronan Receptors; Injections, Intralesional; Lung Neoplasms | 2004 |
Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice.
Topics: Angiogenesis Inhibitors; Animals; Dimethyl Sulfoxide; Dog Diseases; Dogs; Dose-Response Relationship | 2004 |
Development of a high-throughput robotic fluorescence-based assay for HsEg5 inhibitor screening.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Cell Line, Tumor; Colorime | 2005 |
Inhibition of B16 melanoma metastases with the ruthenium complex imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate and down-regulation of tumor cell invasion.
Topics: Animals; Antineoplastic Agents; Cell Adhesion Molecules; Cell Cycle; Cell Line, Tumor; Dimethyl Sulf | 2006 |
In-vitro 1H-MRS of excised rabbit lung: evaluation of preservation method of the lung using 10% DMSO solution.
Topics: Animals; Choline; Creatine; Dimethyl Sulfoxide; Lactic Acid; Lung; Lung Neoplasms; Magnetic Resonanc | 2005 |
The role of cisplatin and NAMI-A plasma-protein interactions in relation to combination therapy.
Topics: alpha-Macroglobulins; Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cisplatin; Di | 2006 |
Enhancement of lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells by treatment with highly polar compounds.
Topics: Animals; Carcinoma; Cathepsins; Cell Adhesion; Cycloheximide; Dimethyl Sulfoxide; Lung Neoplasms; Mi | 1984 |
Enhanced metastatic potential of cloned low-metastatic Lewis lung carcinoma cells treated in vitro with dimethyl sulfoxide.
Topics: Animals; Cell Adhesion; Cell Aggregation; Cell Line; Clone Cells; Dimethyl Sulfoxide; Hydrolases; Ki | 1984 |
Cyclophosphamide and dimethylsulfoxide in the treatment of squamous carcinoma of the lung. Therapeutic efficacy, toxicity, and pharmacokinetics.
Topics: Adult; Aged; Alkylating Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Dimethyl Sulfoxide; Drug | 1981 |
[Dimexide in the overall treatment of radiation pneumonitis in lung cancer patients].
Topics: Aged; Dimethyl Sulfoxide; Drug Evaluation; Humans; Lung Neoplasms; Middle Aged; Pneumonia; Radiation | 1980 |
Antimetastatic action and toxicity on healthy tissues of Na[trans-RuCl4(DMSO)Im] in the mouse.
Topics: Animals; Body Weight; Dimethyl Sulfoxide; DNA, Neoplasm; Drug Administration Schedule; Kidney; Liver | 1994 |
Induction of lung and liver tumors by fluoranthene in a preweanling CD-1 mouse bioassay.
Topics: Animals; Animals, Newborn; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Female; Fluorenes; | 1993 |
Functional, biochemical and morphological studies on human bronchi after cryopreservation.
Topics: Acetylcholine; Adult; Aged; Bronchi; Cryopreservation; Dimethyl Sulfoxide; Female; Humans; In Vitro | 1995 |
Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents.
Topics: Acetamides; Adenocarcinoma; Alkaline Phosphatase; Animals; Antineoplastic Agents; Biomarkers; Butyra | 1996 |
Down-regulation of tumour gelatinase/inhibitor balance and preservation of tumour endothelium by an anti-metastatic ruthenium complex.
Topics: Acridine Orange; Animals; Antineoplastic Agents; Collagenases; Coloring Agents; Dimethyl Sulfoxide; | 1996 |
Treatment of residual metastases with Na[trans-RuCl4 (DMSO)lm] and ruthenium uptake by tumor cells.
Topics: Animals; Antineoplastic Agents; Carcinoma; Dimethyl Sulfoxide; Lung Neoplasms; Mammary Neoplasms, Ex | 1996 |
Expression of cathepsin B in small cell lung carcinoma cells in relation to in vitro invasiveness.
Topics: Carcinoma, Small Cell; Cathepsin B; Cell Aggregation; Cell Division; Cell Line; Cells, Cultured; Dim | 1998 |
Comparison of the effects of the antimetastatic compound ImH[trans-RuCl4(DMSO)Im] (NAMI-A) on the arthritic rat and on MCa mammary carcinoma in mice.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis; Dimethyl Sulfoxide; Female; Lun | 1998 |
Activator protein-1 is the preferred transcription factor for cooperative interaction with nuclear factor-kappaB in respiratory syncytial virus-induced interleukin-8 gene expression in airway epithelium.
Topics: Acetylcysteine; Antioxidants; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Cyclic N | 1998 |
Pharmacological control of lung metastases of solid tumours by a novel ruthenium complex.
Topics: Animals; Antineoplastic Agents; Carcinoma; Dimethyl Sulfoxide; Female; Flow Cytometry; Lung Neoplasm | 1998 |
Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle; Cell Survival; Cisplatin; Dimethyl Su | 1998 |
In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Survival; Cisplatin; Dimethyl Sulfoxide; DNA, Neopl | 1999 |
Reduction of lung metastasis by ImH[trans-RuCl4(DMSO)Im]: mechanism of the selective action investigated on mouse tumors.
Topics: Animals; Antineoplastic Agents; Body Weight; Carcinoma, Lewis Lung; Cell Cycle; Dimethyl Sulfoxide; | 1999 |
Abrogation of cyclin D1 expression predisposes lung cancer cells to serum deprivation-induced apoptosis.
Topics: Antioxidants; Apoptosis; Ascorbic Acid; Culture Media, Serum-Free; Cyclin D1; Dimethyl Sulfoxide; DN | 1999 |
Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571.
Topics: Animals; Antineoplastic Agents; Benzamides; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; C | 2000 |
Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A.
Topics: Animals; Antineoplastic Agents; Cell Division; Dimethyl Sulfoxide; Female; Lung Neoplasms; Mammary N | 2002 |
Cilia formation in cultures of human lung cancer cells treated with dimethyl sulfoxide.
Topics: Cells, Cultured; Cilia; Dimethyl Sulfoxide; Lung Neoplasms | 1976 |
Increased expression of differentiation markers can accompany laminin-induced attachment of small cell lung cancer cells.
Topics: Acetamides; Actins; Bucladesine; Carcinoma, Small Cell; Cell Adhesion; Cell Differentiation; Cell Di | 1992 |
Carcinogenesis associated with dimethyl sulfoxide.
Topics: Adenocarcinoma; Animals; Carcinoma, Transitional Cell; Dimethyl Sulfoxide; Lung Neoplasms; Rats; Rat | 1992 |
Na[trans-RuCl4(DMSO)Im], a metal complex of ruthenium with antimetastatic properties.
Topics: Animals; Antineoplastic Agents; Cisplatin; Dimethyl Sulfoxide; Drug Administration Schedule; Female; | 1992 |
Effects of the Ru(III) complexes [mer-RuCl3(DMSO)2Im]degrees and Na[trans-RuCl4(DMSO)Im] on solid mouse tumors.
Topics: Animals; Carcinoma; Cisplatin; Dimethyl Sulfoxide; Dosage Forms; Drug Administration Schedule; Drug | 1992 |
Alteration of the metastatic potential of line 1 lung carcinoma cells: opposite effects of class I antigen induction by interferons versus DMSO or gene transfection.
Topics: Animals; Carcinoma; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Histocompatibility Antigens Class | 1990 |
Two regions of the H-2 Dd promoter are responsive to dimethylsulfoxide in line 1 cells by a mechanism distinct from IFN-gamma.
Topics: Animals; Base Sequence; Chloramphenicol O-Acetyltransferase; Dimethyl Sulfoxide; H-2 Antigens; Histo | 1992 |
Mechanism of cytolytic T lymphocyte killing of a low class I-expressing tumor.
Topics: Animals; Carcinoma; Clone Cells; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; H-2 Antigens; Histoc | 1991 |
Carcinogenicity studies of tobacco extract in vitamin A-deficient Sprague-Dawley rats.
Topics: Adenoma; Animals; Body Weight; Carcinogenicity Tests; Dimethyl Sulfoxide; Liver; Lung; Lung Neoplasm | 1991 |
Molecular analysis of deficient class I H-2 antigen expression by mouse lung carcinoma cells.
Topics: Animals; beta 2-Microglobulin; Carcinoma; Cell Line; Dimethyl Sulfoxide; Genes, MHC Class I; H-2 Ant | 1988 |
Dimethyl sulfoxide induces expression of H-2 antigens on mouse lung carcinoma cells.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Antigens, Neoplasm; Antigens, Surface; Cell Survival; | 1985 |
Drug targeting to the lungs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Adhesion; Dimethyl Sulfoxide; Doxorubicin; F | 1986 |
Effects of 8-bromoadenosine 3':5'-cyclic monophosphate on proteolytic enzymes, adhesiveness and lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cathepsin B; Cell Adhesion; Cell Line; Clone Cells; Cyclic A | 1986 |
Effect of recombinant monokines, lymphokines, and other agents on clonal proliferation of human lung cancer cell lines.
Topics: Calcitriol; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Di | 1987 |
Differential expression of a tropomyosin isoform in low- and high-metastatic Lewis lung carcinoma cells.
Topics: Animals; Butyrates; Butyric Acid; Cell Division; Dimethyl Sulfoxide; Electrophoresis, Polyacrylamide | 1988 |
Mediation of reduction of spontaneous and experimental pulmonary metastases by ricin A-chain immunotoxin 45-2D9-RTA with potentiation by systemic monensin in mice.
Topics: Ammonium Chloride; Animals; Antigens, Neoplasm; Chloroquine; Dimethyl Sulfoxide; Drug Synergism; Fem | 1988 |
Effect of two inducers of cellular differentiation on the glutathione status of human HL-60 promyelocytic leukaemia and A549 lung carcinoma cells.
Topics: Animals; Carcinoma; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Formamides; Glutathione; Hu | 1987 |
Adhesiveness and morphology of Lewis lung carcinoma variants influence their sensitivity to natural killer cytolysis and their metastatic capacity.
Topics: Animals; Cell Adhesion; Clone Cells; Cytochalasin B; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; | 1987 |
Enhanced immune recognition of H-2 antigen-deficient murine lung carcinoma cells following treatment with dimethyl sulfoxide.
Topics: Animals; Antigens, Neoplasm; Carcinoma; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; H-2 Antigens; | 1985 |
Comparison of two routes of chemical administration on the lung adenoma response in strain A/J mice.
Topics: Adenoma; Administration, Oral; Animals; Caprylates; Carcinogens; Dimethyl Sulfoxide; Female; Injecti | 1986 |
[Induction of lungtumors and tumors of the urinary bladder in rats by di-n-butyl nitrosamine in dimethyl sulfoxide].
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Dimethyl Sulfoxide; Drug Interactions; Injections | 1974 |
Utilization of newborn mice in the bioassay of chemical carcinogens.
Topics: Adenoma; Aflatoxins; Aniline Compounds; Animals; Animals, Newborn; Benzene Derivatives; Biological A | 1969 |