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dimethyl sulfoxide and Liver Dysfunction

dimethyl sulfoxide has been researched along with Liver Dysfunction in 16 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Research Excerpts

ExcerptRelevanceReference
"We studied the preventive effects of dimethyl sulfoxide (DMSO) on experimental hepatic fibrosis induced by dimethylnitrosamine (DMN) in rats."7.71Dimethyl sulfoxide inhibits dimethylnitrosamine-induced hepatic fibrosis in rats. ( Enjoji, M; Kato, M; Kotoh, K; Nakamuta, M; Nakashima, Y; Nawata, H; Ohta, S; Sugimoto, R; Tada, S; Tsuruta, S, 2001)
"We studied the preventive effects of dimethyl sulfoxide (DMSO) on experimental hepatic fibrosis induced by dimethylnitrosamine (DMN) in rats."3.71Dimethyl sulfoxide inhibits dimethylnitrosamine-induced hepatic fibrosis in rats. ( Enjoji, M; Kato, M; Kotoh, K; Nakamuta, M; Nakashima, Y; Nawata, H; Ohta, S; Sugimoto, R; Tada, S; Tsuruta, S, 2001)
"Dimethyl sulfoxide (DMSO) is a very simple compound that has stimulated much controversy in the scientific and popular literature."2.37Dimethyl sulfoxide (DMSO): a review. ( Brayton, CF, 1986)
"Dimethyl sulfoxide (DMSO) has previously been shown to attenuate chloroform (CHCl3) and bromobenzene (BB) induced hepatotoxicity in the rat when a dose of 2."1.30Hepatoprotection by dimethyl sulfoxide. II. Characterization of optimal dose and the latest time of administration for effective protection against chloroform and bromobenzene induced injury. ( Gandolfi, AJ; Lind, RC, 1999)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's2 (12.50)18.2507
2000's6 (37.50)29.6817
2010's1 (6.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Acosta-Cota, SJ1
Castillo-Romero, DJ1
Montes-Ávila, J1
Delgado-Vargas, F1
Báez-Flores, ME1
Noguera-Corona, E1
Osuna-Martínez, U1
Zhao, L1
Yu, Y1
Deng, C1
Masson, MJ1
Carpenter, LD1
Graf, ML1
Pohl, LR1
Jaeschke, H2
Kucuk, C1
Ok, E1
Yilmaz, Z1
Sozuer, E1
Muhtaroglu, S1
Arar, M1
Túnez, I1
Muñoz, MC1
Villavicencio, MA1
Medina, FJ1
de Prado, EP1
Espejo, I1
Barcos, M1
Salcedo, M1
Feijóo, M1
Montilla, P1
Cover, C1
Bajt, ML1
Parks, DA1
Bulkley, GB1
Granger, DN1
El-Hage, AN1
Herman, EH1
Ferrans, VJ1
Loeven, KO1
Lind, RC1
Gandolfi, AJ1
Nakamuta, M1
Ohta, S1
Tada, S1
Tsuruta, S1
Sugimoto, R1
Kotoh, K1
Kato, M1
Nakashima, Y1
Enjoji, M1
Nawata, H1
Willson, RA1
Hart, FE1
Brayton, CF1
Weinstein, V1
Oberhauser, E1
Asenjo, A1
Highman, B1
Altland, PD1

Reviews

2 reviews available for dimethyl sulfoxide and Liver Dysfunction

ArticleYear
Role of oxygen-derived free radicals in digestive tract diseases.
    Surgery, 1983, Volume: 94, Issue:3

    Topics: Allopurinol; Animals; Capillary Permeability; Cats; Digestive System Diseases; Dimethyl Sulfoxide; E

1983
Dimethyl sulfoxide (DMSO): a review.
    The Cornell veterinarian, 1986, Volume: 76, Issue:1

    Topics: Absorption; Administration, Topical; Analgesia; Animals; Blood Coagulation; Chemical and Drug Induce

1986

Other Studies

14 other studies available for dimethyl sulfoxide and Liver Dysfunction

ArticleYear
Effect of 4-hydroxychalcone as preventive and curative treatment in Wistar rats with liver injury.
    Canadian journal of physiology and pharmacology, 2022, Oct-01, Volume: 100, Issue:10

    Topics: Animals; Carbon Tetrachloride; Chalcones; Chemical and Drug Induced Liver Injury; Dimethyl Sulfoxide

2022
[Expression of sonic hedgehog signaling pathw ay and its inhibition by cyclopamine in rat liver with chronic fluorosis].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2014, Volume: 43, Issue:12

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Dimethyl Sulfoxide; Disease Models, Anim

2014
Pathogenic role of natural killer T and natural killer cells in acetaminophen-induced liver injury in mice is dependent on the presence of dimethyl sulfoxide.
    Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; Cell Culture Techniques; Chemical and D

2008
Innate immunity and acetaminophen-induced liver injury: why so many controversies?
    Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; Chemical and Drug Induced Liver Injury;

2008
The effects of dimethylsulfoxide in experimental obstructive jaundice.
    Acta chirurgica Belgica, 2003, Volume: 103, Issue:4

    Topics: Animals; Dimethyl Sulfoxide; Free Radical Scavengers; Jaundice, Obstructive; Lipid Peroxidation; Liv

2003
Hepato- and neurotoxicity induced by thioacetamide: protective effects of melatonin and dimethylsulfoxide.
    Pharmacological research, 2005, Volume: 52, Issue:3

    Topics: Alanine Transaminase; Ammonia; Animals; Blood Urea Nitrogen; Brain; Catalase; Chemical and Drug Indu

2005
Role of caspases in acetaminophen-induced liver injury.
    Life sciences, 2006, Mar-06, Volume: 78, Issue:15

    Topics: Acetaminophen; Amino Acid Chloromethyl Ketones; Analgesics, Non-Narcotic; Animals; Caspase Inhibitor

2006
Examination of the protective effect of ICRF-187 and dimethyl sulfoxide against acetaminophen-induced hepatotoxicity in Syrian golden hamsters.
    Toxicology, 1983, Volume: 28, Issue:4

    Topics: Acetaminophen; Alanine Transaminase; Animals; Blood Proteins; Chemical and Drug Induced Liver Injury

1983
Hepatic amyloidosis in two Chinese Shar Pei dogs.
    Journal of the American Veterinary Medical Association, 1994, Apr-15, Volume: 204, Issue:8

    Topics: Amyloidosis; Animals; Breeding; Colchicine; Dimethyl Sulfoxide; Dog Diseases; Dogs; Female; Fever; L

1994
Hepatoprotection by dimethyl sulfoxide. II. Characterization of optimal dose and the latest time of administration for effective protection against chloroform and bromobenzene induced injury.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1999, Volume: 51, Issue:6

    Topics: Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Chloroform; Dimethyl Sulfoxide; Dose

1999
Dimethyl sulfoxide inhibits dimethylnitrosamine-induced hepatic fibrosis in rats.
    International journal of molecular medicine, 2001, Volume: 8, Issue:5

    Topics: Animals; Body Weight; Cell Line; Cells, Cultured; Chemical and Drug Induced Liver Injury; Collagen T

2001
In vitro spectral alteration of hepatic cytochrome P-450 by experimental drug injury.
    Research communications in chemical pathology and pharmacology, 1977, Volume: 17, Issue:4

    Topics: Acetaminophen; Animals; Buffers; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Cytoc

1977
Effect of dimethyl sulfoxide on experimental cytosiderosis.
    Acta neurologica latinoamericana, 1969, Volume: 15, Issue:1

    Topics: Animals; Basal Ganglia; Brain; Brain Diseases; Cerebral Cortex; Dimethyl Sulfoxide; Haplorhini; Iron

1969
Effect of demethyl sulfoxide on serum enzymes and tissues of rats given epinephrine and cortisone.
    Life sciences, 1969, Jul-01, Volume: 8, Issue:13

    Topics: Adrenal Glands; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cortisone; Dimethyl Sulf

1969