dimethyl sulfoxide has been researched along with Leukemia L5178 in 6 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Leukemia L5178: An experimental lymphocytic leukemia of mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mouse lymphoma L5178Y cells were treated with dimethyl sulphoxide (DMSO) as a standard solvent or reference agents known to induce oxidative damage (gamma irradiation and potassium bromate) or alkylation (methyl methanesulfonate, MMS; ethylnitrosurea, ENU)." | 1.33 | hOGG1 recognizes oxidative damage using the comet assay with greater specificity than FPG or ENDOIII. ( Martin, EA; O'Donovan, MR; Smith, CC, 2006) |
| "Chromosome abnormalities were present in cells from 12% (7/60) of the UC colonies, but there was no apparent relationship between colony diameter and the presence of chromosomal abnormalities." | 1.28 | Chromosome analysis of small and large L5178Y mouse lymphoma cell colonies: comparison of trifluorothymidine-resistant and unselected cell colonies from mutagen-treated and control cultures. ( Blazak, WF; Caspary, WJ; Los, FJ; Rudd, CJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, CC | 1 |
| O'Donovan, MR | 1 |
| Martin, EA | 1 |
| Miyazaki, N | 1 |
| Nakano, H | 1 |
| Ito, A | 2 |
| Shinohara, K | 2 |
| Doerr, CL | 1 |
| Harrington-Brock, K | 1 |
| Moore, MM | 1 |
| Blazak, WF | 1 |
| Los, FJ | 1 |
| Rudd, CJ | 1 |
| Caspary, WJ | 1 |
| Cobb, RR | 1 |
| Martin, J | 1 |
| Korytynski, E | 1 |
| Monteith, L | 1 |
| Hughes, TJ | 1 |
6 other studies available for dimethyl sulfoxide and Leukemia L5178
| Article | Year |
|---|---|
hOGG1 recognizes oxidative damage using the comet assay with greater specificity than FPG or ENDOIII.
Topics: Animals; Bromates; Comet Assay; Deoxyribonuclease (Pyrimidine Dimer); Dimethyl Sulfoxide; DNA Damage | 2006 |
Different contributions of the indirect effects of gamma-rays on the cytotoxicity in M10 and XRCC4 transfected M10 cells.
Topics: Animals; Cell Death; Cell Survival; Cesium Radioisotopes; Dimethyl Sulfoxide; DNA Repair; DNA-Bindin | 2007 |
Dual mode cytotoxicities of reactive oxygens on L5178Y radiosensitive mutant M10.
Topics: Animals; Cell Survival; Dimethyl Sulfoxide; Hydrogen Peroxide; Leukemia L5178; Mice; Mutation; Phena | 1992 |
Micronucleus, chromosome aberration, and small-colony TK mutant analysis to quantitate chromosomal damage in L5178Y mouse lymphoma cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoacridines; Amsacrine; Animals; Bleomycin; Chromosome Aberrati | 1989 |
Chromosome analysis of small and large L5178Y mouse lymphoma cell colonies: comparison of trifluorothymidine-resistant and unselected cell colonies from mutagen-treated and control cultures.
Topics: Animals; Chromosome Aberrations; Dimethyl Sulfoxide; Hycanthone; Leukemia L5178; Leukemia, Experimen | 1989 |
Preliminary molecular analysis of the TK locus in L5178Y large- and small-colony mouse lymphoma cell mutants.
Topics: Animals; Blotting, Southern; Chromosome Mapping; Dimethyl Sulfoxide; DNA, Neoplasm; Leukemia L5178; | 1989 |