dimethyl sulfoxide has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 14 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dimethyl sulfoxide (DMSO) has been used for years as a cryoprotectant agent; it acts by penetrating the cell and binding water molecules and it has been described as harmless for the individual who receives it in limited amounts." | 2.45 | Dimethyl sulfoxide-induced toxicity in cord blood stem cell transplantation: report of three cases and review of the literature. ( Gómez-Almaguer, D; Hernández-Arizpe, A; López-Otero, A; Mancías-Guerra, C; Rodríguez-Romo, LN; Ruiz-Argüelles, GJ; Ruiz-Delgado, GJ; Tamez-Gómez, EL, 2009) |
| " We speculate that one of the triggers of the HUS-like episode could have been renal microangiopathy caused by the long-term administration of interferon-alpha before the stem cell transplantation." | 1.32 | [Hemolytic uremic syndrome-like episode following nonmyeloablative hematopoietic stem cell transplantation in a patient with chronic myeloid leukemia]. ( Hirokawa, M; Kawabata, Y; Kume, M; Miura, I; Sawada, K; Takahashi, N, 2003) |
| "Differentiation of HL60, several chronic myelogenous leukemias, a monocytic leukemia (THP-1), and a monoblastoid leukemia (U-937) could be induced by phorbol ester, 1,25-dihydroxy vitamin D3, dimethyl sulfoxide, or cyclic AMP analogues." | 1.28 | Differentiation-induced changes in protein-tyrosine phosphatase activity and commensurate expression of CD45 in human leukemia cell lines. ( Brautigan, DL; Buzzi, M; Fast, LD; Frackelton, AR; Lombardi, AJ; Lu, L; Posner, MR, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, YC | 1 |
| Huang, CP | 1 |
| Lin, CP | 1 |
| Yang, KC | 1 |
| Lei, YJ | 1 |
| Wang, HP | 1 |
| Kuo, YH | 1 |
| Chen, YJ | 1 |
| Ruiz-Delgado, GJ | 1 |
| Mancías-Guerra, C | 1 |
| Tamez-Gómez, EL | 1 |
| Rodríguez-Romo, LN | 1 |
| López-Otero, A | 1 |
| Hernández-Arizpe, A | 1 |
| Gómez-Almaguer, D | 1 |
| Ruiz-Argüelles, GJ | 1 |
| Takahashi, N | 1 |
| Miura, I | 1 |
| Kume, M | 1 |
| Kawabata, Y | 1 |
| Hirokawa, M | 1 |
| Sawada, K | 1 |
| Zutter, MM | 1 |
| Painter, AA | 1 |
| Staatz, WD | 1 |
| Tsung, YL | 1 |
| Herwig, S | 1 |
| Su, Q | 1 |
| Zhang, W | 1 |
| Ma, Y | 1 |
| Tempst, P | 1 |
| Sharma, HW | 1 |
| Sokoloski, JA | 1 |
| Perez, JR | 1 |
| Maltese, JY | 1 |
| Sartorelli, AC | 1 |
| Stein, CA | 1 |
| Nichols, G | 1 |
| Khaled, Z | 1 |
| Telang, NT | 1 |
| Narayanan, R | 1 |
| Giardina, SL | 1 |
| Coffman, JD | 1 |
| Young, HA | 1 |
| Potter, SJ | 1 |
| Frey, JL | 1 |
| Ortaldo, JR | 1 |
| Anderson, SK | 1 |
| Di Noto, R | 1 |
| Luciano, L | 1 |
| Lo Pardo, C | 1 |
| Ferrara, F | 1 |
| Frigeri, F | 1 |
| Mercuro, O | 1 |
| Lombardi, ML | 1 |
| Pane, F | 1 |
| Vacca, C | 1 |
| Manzo, C | 1 |
| Salvatore, F | 1 |
| Rotoli, B | 1 |
| Del Vecchio, L | 1 |
| Buzzi, M | 1 |
| Lu, L | 1 |
| Lombardi, AJ | 1 |
| Posner, MR | 1 |
| Brautigan, DL | 1 |
| Fast, LD | 1 |
| Frackelton, AR | 1 |
| Rehemtulla, A | 1 |
| Arndt, A | 1 |
| Hart, DA | 1 |
| Sasaki, R | 1 |
| Yoshida, H | 1 |
| Miura, Y | 1 |
| Takaku, F | 1 |
| Bütler, TM | 1 |
| Ziemiecki, A | 1 |
| Friis, RR | 1 |
| Vestal, DJ | 1 |
| Davis, BH | 1 |
| Enns, CA | 1 |
| Zinzar, S | 1 |
| Ohnuma, T | 1 |
| Holland, JF | 1 |
1 review available for dimethyl sulfoxide and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
| Article | Year |
|---|---|
Dimethyl sulfoxide-induced toxicity in cord blood stem cell transplantation: report of three cases and review of the literature.
Topics: Antigens, CD34; Child; Cord Blood Stem Cell Transplantation; Cryoprotective Agents; Dimethyl Sulfoxi | 2009 |
13 other studies available for dimethyl sulfoxide and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
| Article | Year |
|---|---|
Naturally Occurring Bicoumarin Compound Daphnoretin Inhibits Growth and Induces Megakaryocytic Differentiation in Human Chronic Myeloid Leukemia Cells.
Topics: Antiviral Agents; Cell Differentiation; Dimethyl Sulfoxide; Humans; Leukemia, Myelogenous, Chronic, | 2022 |
[Hemolytic uremic syndrome-like episode following nonmyeloablative hematopoietic stem cell transplantation in a patient with chronic myeloid leukemia].
Topics: Cryopreservation; Dimethyl Sulfoxide; Female; Hemolytic-Uremic Syndrome; Humans; Interferon-alpha; L | 2003 |
Regulation of alpha 2 integrin gene expression in cells with megakaryocytic features: a common theme of three necessary elements.
Topics: Antigens, CD; Burkitt Lymphoma; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Gene Expression Regu | 1995 |
Distinct temporal patterns of defensin mRNA regulation during drug-induced differentiation of human myeloid leukemia cells.
Topics: Acetamides; Biomarkers; Blood Proteins; Cell Differentiation; Cycloheximide; Cytokines; Dactinomycin | 1996 |
Differentiation of immortal cells inhibits telomerase activity.
Topics: Animals; Base Sequence; Butyrates; Butyric Acid; Calcitriol; Cell Differentiation; Cell Line; Cell N | 1995 |
Association of the expression of an SR-cyclophilin with myeloid cell differentiation.
Topics: Animals; Antibodies, Monoclonal; Blood Proteins; Cell Differentiation; Chlorocebus aethiops; Dimethy | 1996 |
JURL-MK1 (c-kit(high)/CD30-/CD40-) and JURL-MK2 (c-kit(low)/CD30+/CD40+) cell lines: 'two-sided' model for investigating leukemic megakaryocytopoiesis.
Topics: Antigens, Surface; CD40 Antigens; Cell Differentiation; Cells, Cultured; Chromosome Banding; Dimethy | 1997 |
Differentiation-induced changes in protein-tyrosine phosphatase activity and commensurate expression of CD45 in human leukemia cell lines.
Topics: Antigens, CD; Cell Differentiation; Dimethyl Sulfoxide; Electrophoresis; Histocompatibility Antigens | 1992 |
Induction of plasminogen activator inhibitor type 2 expression during differentiation of human K562 cells towards a macrophage phenotype.
Topics: Base Sequence; Cell Differentiation; Cholecalciferol; Dimethyl Sulfoxide; DNA Probes; Gene Expressio | 1990 |
Erythroid differentiation of K-562 cells induced by ethidium bromide.
Topics: Acridine Orange; Cell Differentiation; Cell Line; Cytarabine; Dimethyl Sulfoxide; DNA Polymerase II; | 1991 |
Megakaryocytic differentiation of K562 cells is associated with changes in the cytoskeletal organization and the pattern of chromatographically distinct forms of phosphotyrosyl-specific protein phosphatases.
Topics: Cell Differentiation; Cell Division; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Human | 1990 |
A rapid redistribution of the transferrin receptor to the cell surface of HL-60 cells and K562 cells upon treatment with dimethyl sulfoxide due to slowing of endocytosis.
Topics: Cell Line; Cell Membrane; Dimethyl Sulfoxide; Endocytosis; Humans; Kinetics; Leukemia, Myelogenous, | 1990 |
Effects of simultaneous and sequential exposure to granulocytic and monocytic inducers on the choice of differentiation pathway in HL-60 promyelocytic leukemia cells.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Drug Synergism; Granulocytes; Humans; Leukemia, | 1989 |