dimethyl sulfoxide has been researched along with Kidney Papillary Necrosis in 2 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Kidney Papillary Necrosis: A complication of kidney diseases characterized by cell death involving KIDNEY PAPILLA in the KIDNEY MEDULLA. Damages to this area may hinder the kidney to concentrate urine resulting in POLYURIA. Sloughed off necrotic tissue may block KIDNEY PELVIS or URETER. Necrosis of multiple renal papillae can lead to KIDNEY FAILURE.
Excerpt | Relevance | Reference |
---|---|---|
"When diphenylamine in DMSO was administered orally to male Syrian hamsters (400, 600 or 800 mg/kg body weight/day for up to 9 days), the incidence of renal papillary necrosis was almost zero." | 1.28 | Decreased incidence of diphenylamine-induced renal papillary necrosis in Syrian hamsters given dimethylsulphoxide. ( Carlton, WW; Lenz, SD, 1991) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Wolf, DC | 1 |
Carlton, WW | 2 |
Turek, JJ | 1 |
Lenz, SD | 1 |
2 other studies available for dimethyl sulfoxide and Kidney Papillary Necrosis
Article | Year |
---|---|
Experimental renal papillary necrosis in the Mongolian gerbil (Meriones unguiculatus).
Topics: Animals; Dimethyl Sulfoxide; Diuresis; Ethylamines; Female; Gerbillinae; Kidney Medulla; Kidney Papi | 1992 |
Decreased incidence of diphenylamine-induced renal papillary necrosis in Syrian hamsters given dimethylsulphoxide.
Topics: Administration, Oral; Animals; Cricetinae; Dimethyl Sulfoxide; Diphenylamine; Dose-Response Relation | 1991 |