dimethyl sulfoxide has been researched along with Invasiveness, Neoplasm in 24 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We found that polar compounds and butyric acid, which are known to alter the expressions of normally silent genes, enhanced the lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells." | 4.77 | Modification of the metastatic potential of tumor cells by drugs. ( Takenaga, K, 1986) |
| "Using a panel of pharmacological inhibitors (BAY 43-9006, PD98059, U0126, wortmannin, LY294002) we inhibited the MAPK and AKT signalling pathways at different levels and evaluated the effects on growth, survival and invasion of melanoma cells in monolayer and organotypic skin culture." | 3.74 | Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment. ( Busch, S; Garbe, C; Herlyn, M; Kulms, D; Lasithiotakis, K; Maczey, E; Meier, F; Schittek, B, 2007) |
| "Overall, our study revealed a novel metastasis-promoting function of SOCS5 in HCC, acting via the PI3K/Akt/mTOR-mediated autophagy pathway." | 1.51 | SOCS5 inhibition induces autophagy to impair metastasis in hepatocellular carcinoma cells via the PI3K/Akt/mTOR pathway. ( Chua, MS; Han, B; Li, H; Liu, S; Luo, D; Sun, C; Wang, S; Zhang, M; Zhang, S, 2019) |
| "A major challenge in the management of prostate cancer (PC) is to limit tumor growth and metastases." | 1.48 | Methylsulfonylmethane (organic sulfur) induces apoptosis and decreases invasiveness of prostate cancer cells. ( Domińska, K; Habrowska-Górczyńska, DE; Kowalska, K; Piastowska-Ciesielska, AW; Urbanek, KA, 2018) |
| "CAY10591 treatment dose- and time-dependently increased SIRT1 level and activity." | 1.46 | CAY10591, a SIRT1 activator, suppresses cell growth, invasion, and migration in gingival epithelial carcinoma cells. ( Mikami, Y; Murofushi, T; Suzuki, N; Tsuda, H; Yamaguchi, Y, 2017) |
| "Melanoma is a highly metastatic and lethal form of skin cancer." | 1.40 | BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling. ( Cook, M; Girotti, MR; Gore, M; Hayes, A; Larkin, J; Lorigan, P; Marais, R; Niculescu-Duvaz, D; Pedersen, M; Sanchez-Laorden, B; Saturno, G; Springer, C; Turajlic, S; Viros, A; Zambon, A, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.33) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 12 (50.00) | 29.6817 |
| 2010's | 6 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, M | 1 |
| Liu, S | 1 |
| Chua, MS | 1 |
| Li, H | 1 |
| Luo, D | 1 |
| Wang, S | 1 |
| Zhang, S | 1 |
| Han, B | 1 |
| Sun, C | 1 |
| Murofushi, T | 1 |
| Tsuda, H | 1 |
| Mikami, Y | 1 |
| Yamaguchi, Y | 1 |
| Suzuki, N | 1 |
| Kowalska, K | 1 |
| Habrowska-Górczyńska, DE | 1 |
| Domińska, K | 1 |
| Urbanek, KA | 1 |
| Piastowska-Ciesielska, AW | 1 |
| Sanchez-Laorden, B | 1 |
| Viros, A | 1 |
| Girotti, MR | 1 |
| Pedersen, M | 1 |
| Saturno, G | 1 |
| Zambon, A | 1 |
| Niculescu-Duvaz, D | 1 |
| Turajlic, S | 1 |
| Hayes, A | 1 |
| Gore, M | 1 |
| Larkin, J | 1 |
| Lorigan, P | 1 |
| Cook, M | 1 |
| Springer, C | 1 |
| Marais, R | 1 |
| Valls-Mateus, M | 1 |
| Román, LS | 1 |
| Macho, J | 1 |
| Nadal, A | 1 |
| Bernal-Sprekelsen, M | 1 |
| Vilaseca, I | 1 |
| Horiguchi, A | 1 |
| Asano, T | 2 |
| Ito, K | 1 |
| Sumitomo, M | 1 |
| Hayakawa, M | 1 |
| Wang, W | 1 |
| Zhang, N | 1 |
| Wang, J | 1 |
| Bu, XM | 1 |
| Zhao, CH | 1 |
| Bergamo, A | 6 |
| Gava, B | 3 |
| Alessio, E | 4 |
| Mestroni, G | 2 |
| Serli, B | 2 |
| Cocchietto, M | 5 |
| Zorzet, S | 5 |
| Sava, G | 7 |
| Turrin, C | 1 |
| Vita, F | 1 |
| Soranzo, M | 1 |
| Zabucchi, G | 1 |
| DiGiovine, S | 1 |
| Pezzoni, G | 1 |
| Sartor, L | 1 |
| Garbisa, S | 1 |
| Stocco, G | 1 |
| Casarsa, C | 1 |
| Schwarzer, R | 1 |
| Tondera, D | 1 |
| Arnold, W | 1 |
| Giese, K | 1 |
| Klippel, A | 1 |
| Kaufmann, J | 1 |
| Spessotto, P | 1 |
| Jeong, YI | 1 |
| Kim, SH | 1 |
| Jung, TY | 1 |
| Kim, IY | 1 |
| Kang, SS | 1 |
| Jin, YH | 1 |
| Ryu, HH | 1 |
| Sun, HS | 1 |
| Jin, S | 1 |
| Kim, KK | 1 |
| Ahn, KY | 1 |
| Jung, S | 1 |
| Meier, F | 1 |
| Busch, S | 1 |
| Lasithiotakis, K | 1 |
| Kulms, D | 1 |
| Garbe, C | 1 |
| Maczey, E | 1 |
| Herlyn, M | 1 |
| Schittek, B | 1 |
| Griffith, D | 1 |
| Cecco, S | 1 |
| Zangrando, E | 1 |
| Marmion, CJ | 1 |
| Maehara, M | 1 |
| Yagita, M | 1 |
| Isobe, Y | 1 |
| Hoshino, T | 1 |
| Nakagawara, G | 1 |
| Popowicz, P | 1 |
| Engel, G | 1 |
| Marshall, H | 1 |
| Linder, S | 1 |
| Nakae, T | 1 |
| Horai, T | 1 |
| Imamura, F | 1 |
| Akedo, H | 1 |
| Higashino, K | 1 |
| Vajkoczy, P | 1 |
| Menger, MD | 1 |
| Goldbrunner, R | 1 |
| Ge, S | 1 |
| Fong, TA | 1 |
| Vollmar, B | 1 |
| Schilling, L | 1 |
| Ullrich, A | 1 |
| Hirth, KP | 1 |
| Tonn, JC | 1 |
| Schmiedek, P | 1 |
| Rempel, SA | 1 |
| Sorc, A | 1 |
| Iengo, E | 1 |
| Bentel, JM | 1 |
| Rhodes, GC | 1 |
| Markus, I | 1 |
| Smith, GJ | 1 |
| Takenaga, K | 1 |
| Ossowski, L | 1 |
2 reviews available for dimethyl sulfoxide and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Ruthenium anticancer drugs.
Topics: Antineoplastic Agents; Cell Cycle; Dimethyl Sulfoxide; Humans; Mitogen-Activated Protein Kinases; Ne | 2004 |
Modification of the metastatic potential of tumor cells by drugs.
Topics: Animals; Azacitidine; Butyrates; Butyric Acid; Carcinoma; Cell Division; Cell Line; Cells, Cultured; | 1986 |
22 other studies available for dimethyl sulfoxide and Invasiveness, Neoplasm
| Article | Year |
|---|---|
SOCS5 inhibition induces autophagy to impair metastasis in hepatocellular carcinoma cells via the PI3K/Akt/mTOR pathway.
Topics: Animals; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Dimethyl Sulfoxide; | 2019 |
CAY10591, a SIRT1 activator, suppresses cell growth, invasion, and migration in gingival epithelial carcinoma cells.
Topics: Cell Division; Cell Line, Tumor; Cyclopentanes; Dimethyl Sulfoxide; Gingival Neoplasms; Humans; Neop | 2017 |
Methylsulfonylmethane (organic sulfur) induces apoptosis and decreases invasiveness of prostate cancer cells.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movem | 2018 |
BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling.
Topics: Animals; Blotting, Western; Cell Shape; Dimethyl Sulfoxide; Drug Resistance, Neoplasm; Enzyme-Linked | 2014 |
Transoral ultrasonic surgery of pharyngolaryngeal giant hemangioma after ethylene-vinyl alcohol copolymer (Onyx) embolization.
Topics: Aged; Combined Modality Therapy; Dimethyl Sulfoxide; Embolization, Therapeutic; Follow-Up Studies; H | 2017 |
Pharmacological inhibitor of fatty acid synthase suppresses growth and invasiveness of renal cancer cells.
Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Carcinoma, Renal Cell; Cell Count; Cell | 2008 |
Inhibition of proliferation, viability, migration and invasion of gastric cancer cells by Aurora-A deletion.
Topics: Aurora Kinases; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dimethyl Sulfoxi | 2011 |
Ruthenium-based NAMI-A type complexes with in vivo selective metastasis reduction and in vitro invasion inhibition unrelated to cell cytotoxicity.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Dimethyl Sulfoxide; G2 Phase; Humans; Lung Ne | 2002 |
Dual Action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cell Adhesion; Cell Division; | 2003 |
Reduction of in vivo lung metastases by dinuclear ruthenium complexes is coupled to inhibition of in vitro tumour invasion.
Topics: Animals; Cell Line, Tumor; Collagen; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Comb | 2004 |
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.
Topics: Apoptosis; Cell Hypoxia; Cell Line, Tumor; Chromones; Cobalt; Dimethyl Sulfoxide; Gene Expression; H | 2005 |
Inhibition of B16 melanoma metastases with the ruthenium complex imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate and down-regulation of tumor cell invasion.
Topics: Animals; Antineoplastic Agents; Cell Adhesion Molecules; Cell Cycle; Cell Line, Tumor; Dimethyl Sulf | 2006 |
Polyion complex micelles composed of all-trans retinoic acid and poly (ethylene glycol)-grafted-chitosan.
Topics: Adsorption; Antineoplastic Agents; Brain Neoplasms; Carbohydrate Sequence; Cell Line, Tumor; Cell Su | 2006 |
Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment.
Topics: Androstadienes; Apoptosis; Benzenesulfonates; Blotting, Western; Cell Line, Tumor; Cell Proliferatio | 2007 |
Ruthenium(III) dimethyl sulfoxide pyridinehydroxamic acid complexes as potential antimetastatic agents: synthesis, characterisation and in vitro pharmacological evaluation.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Dimethyl Sulfox | 2008 |
Dimethyl sulfoxide (DMSO) increases expression of sialyl Lewis x antigen and enhances adhesion of human gastric carcinoma (NUGC4) cells to activated endothelial cells.
Topics: Antibodies, Monoclonal; Antigens, Tumor-Associated, Carbohydrate; Carcinoma; Cell Adhesion; Cell Adh | 1993 |
Repression of stromelysin metalloprotease expression in rat fibrosarcoma cells by dimethylsulfoxide.
Topics: Animals; Blotting, Northern; Cell Adhesion; Cell Division; Cell Line, Transformed; Cell Movement; Di | 1993 |
Expression of cathepsin B in small cell lung carcinoma cells in relation to in vitro invasiveness.
Topics: Carcinoma, Small Cell; Cathepsin B; Cell Aggregation; Cell Division; Cell Line; Cells, Cultured; Dim | 1998 |
Targeting angiogenesis inhibits tumor infiltration and expression of the pro-invasive protein SPARC.
Topics: Angiogenesis Inhibitors; Animals; Biomarkers, Tumor; Cell Division; Cell Movement; Dimethyl Sulfoxid | 2000 |
Lack of In vitro cytotoxicity, associated to increased G(2)-M cell fraction and inhibition of matrigel invasion, may predict In vivo-selective antimetastasis activity of ruthenium complexes.
Topics: Animals; Antineoplastic Agents; Collagen; Dimethyl Sulfoxide; Drug Combinations; G2 Phase; Humans; L | 2000 |
Enhanced invasiveness and metastatic potential of epithelial cell lines cultured in the presence of dimethyl sulphoxide.
Topics: Animals; Cell Line; Clone Cells; Dimethyl Sulfoxide; Epithelium; Immune Tolerance; Mice; Mice, Inbre | 1990 |
Plasminogen activator dependent pathways in the dissemination of human tumor cells in the chick embryo.
Topics: Allantois; Animals; Catalysis; Chick Embryo; Chorion; Dimethyl Sulfoxide; Humans; Immunoglobulin G; | 1988 |