Page last updated: 2024-10-18

dimethyl sulfoxide and Innate Inflammatory Response

dimethyl sulfoxide has been researched along with Innate Inflammatory Response in 95 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Research Excerpts

ExcerptRelevanceReference
"The anti-inflammatory properties of topical ocular dimethyl sulfoxide (DMSO) were investigated using a standard experimental model of an acute inflammatory ocular inflammation."9.04Effects of dimethyl sulfoxide on ocular inflammation. ( Fraunfelder, FT; Hanna, C; Meyer, SM, 1977)
"The anti-inflammatory properties of topical ocular dimethyl sulfoxide (DMSO) were investigated using a standard experimental model of an acute inflammatory ocular inflammation."5.04Effects of dimethyl sulfoxide on ocular inflammation. ( Fraunfelder, FT; Hanna, C; Meyer, SM, 1977)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"We investigated whether capsaicin induces itching in skin with existing inflammation."3.77Capsaicin induces reflex scratching in inflamed skin. ( Ji, W; Liang, J; Xiao, G, 2011)
"In order to investigate the influence of antioxidative/anti-inflammatory combination therapy (AACT) with dimethyl sulfoxide (DMSO), chlorpromazine (CPZ) and vitamin E upon the activity of the inflammation, plasma lipid peroxide was measured as thiobarbituric acid reactive substance (TBARS) 12 hrs postoperatively in the modified cecal ligation sepsis model in the mouse."3.67Plasma lipid peroxides in murine sepsis--sex differences and effect of antioxidative/anti-inflammatory therapy. ( Marinkovic, D; Zuyderhoudt, FM, 1988)
" As a Generally Recognized As Safe (GRAS) approved substance, MSM is well-tolerated by most individuals at dosages of up to four grams daily, with few known and mild side effects."2.55Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. ( Benjamin, RL; Bloomer, RJ; Butawan, M, 2017)
"Endovascular occlusion of cerebral arteriovenous malformations (AVM) is often utilized as adjunctive therapy in combination with radiosurgery or microsurgery."2.50Embolization-induced angiogenesis in cerebral arteriovenous malformations. ( Buell, TJ; Ding, D; Liu, KC; Starke, RM; Webster Crowley, R, 2014)
"Dimethyl sulfoxide (DMSO) is a very simple compound that has stimulated much controversy in the scientific and popular literature."2.37Dimethyl sulfoxide (DMSO): a review. ( Brayton, CF, 1986)
"Chronic obstructive pulmonary disease (COPD) is a major, incurable respiratory condition that is primarily caused by cigarette smoking (CS)."1.91Cigarette smoke-induced pulmonary impairment is associated with social recognition memory impairments and alterations in microglial profiles within the suprachiasmatic nucleus of the hypothalamus. ( Akhtar, A; Alateeq, R; Bozinovski, S; Brassington, K; Chan, SMH; De Luca, SN; Dobric, A; Mou, K; Seow, HJ; Vlahos, R; Wang, H, 2023)
" Three days prior to and one day after a race, the daily dosage was doubled."1.72Optimized Curcumin, Pomegranate Extract, and Methylsulfonylmethane Reduce Acute, Systemic Inflammatory Response to a Half-marathon Race. ( Davis, AA; Gary, MA; McFarlin, BK; Michalik, S; Tanner, EA, 2022)
"Inflammation could play a role in cerebral vasospasm after subarachnoid hemorrhage (SAH)."1.33Role of c-Jun N-terminal kinase in cerebral vasospasm after experimental subarachnoid hemorrhage. ( Calvert, JW; Yamaguchi, M; Yatsushige, H; Zhang, JH; Zhou, C, 2005)
" In addition, repeated injection of mice with a physiologically relevant dosage of DMSO did not enhance the lethality of either E."1.27Effect of dimethyl sulfoxide on the in vitro and in vivo bactericidal activity of human and mouse neutrophils and mononuclear phagocytes. ( Campbell, PA; Czuprynski, CJ; Henson, PM, 1984)
"Endometrial fibrosis is a major cause of infertility in broodmares."1.27Histopathologic effects of dimethyl sulfoxide on equine endometrium. ( Frazer, GS; Rossol, TJ; Threlfall, WR; Weisbrode, SE, 1988)

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-199048 (50.53)18.7374
1990's6 (6.32)18.2507
2000's12 (12.63)29.6817
2010's12 (12.63)24.3611
2020's17 (17.89)2.80

Authors

AuthorsStudies
Miller, L1
Thompson, K1
Pavlenco, C1
Mettu, VS1
Haverkamp, H1
Skaufel, S1
Basit, A1
Prasad, B1
Larsen, J1
Miao, Y1
Niu, D1
Wang, Z1
Wang, J1
Wu, Z1
Bao, J1
Jin, X1
Li, R1
Ishfaq, M1
Li, J2
Maneechote, C1
Khuanjing, T1
Ongnok, B1
Arinno, A1
Prathumsap, N1
Chunchai, T1
Arunsak, B1
Nawara, W1
Chattipakorn, SC1
Chattipakorn, N1
Masuki, H1
Uematsu, T1
Kawabata, H1
Sato, A1
Watanabe, T1
Tsujino, T1
Nakamura, M1
Okubo, M1
Kawase, T1
Zhang, J2
Lu, Y1
Yu, P1
Li, Z1
Liu, Y2
Tang, X1
Yu, S1
Rostevanov, IS1
Betesh-Abay, B1
Nassar, A1
Rubin, E1
Uzzan, S1
Kaplanski, J1
Biton, L1
Azab, AN1
Qiu, H1
Huang, Y1
Shen, C1
Dai, L1
Su, Q1
Zhi, Y1
Fang, Q1
Shi, C1
Li, W1
De Luca, SN1
Chan, SMH1
Dobric, A1
Wang, H1
Seow, HJ1
Brassington, K1
Mou, K1
Alateeq, R1
Akhtar, A1
Bozinovski, S1
Vlahos, R1
Kara, A1
Ozkanlar, S1
Fan, T1
Yang, S1
Huang, Z1
Wang, W1
Guo, X1
Pan, S1
Zhang, B1
Xu, Y1
Fang, Y1
Mao, Z1
Hu, H1
Geng, Q1
Medeiros, RCN1
Moraes, JO1
Rodrigues, SDC1
Pereira, LM1
Aguiar, HQDS1
de Cordova, CAS1
Yim Júnior, A1
de Cordova, FM1
Wang, D1
Sennari, Y1
Shen, M1
Morita, K1
Kanazawa, T1
Yoshida, Y1
Jo, ES1
Sp, N1
Kang, DY1
Rugamba, A1
Kim, IH1
Bae, SW1
Liu, Q1
Jang, KJ1
Yang, YM1
Hoang, BX1
Hoang, HQ1
Han, B1
Zakeri, M1
Soltanizadeh, S1
Karimi-Haghighi, S1
Haghparast, A1
Tanner, EA1
Gary, MA1
Michalik, S1
Davis, AA1
McFarlin, BK1
Zhang, HP1
Ma, LQ1
Lv, Y1
Luo, HM1
Li, YM1
Liu, R1
Hu, S1
Ishibashi, M1
Varin, A1
Filomenko, R1
Lopez, T1
Athias, A1
Gambert, P1
Blache, D1
Thomas, C1
Gautier, T1
Lagrost, L1
Masson, D1
Buell, TJ1
Ding, D1
Starke, RM1
Webster Crowley, R1
Liu, KC1
Silveira, ML1
Smiderle, FR1
Moraes, CP1
Borato, DG1
Baggio, CH1
Ruthes, AC1
Wisbeck, E1
Sassaki, GL1
Cipriani, TR1
Furlan, SA1
Iacomini, M1
Singh, A2
Sand, JM1
Bauer, SJ1
Hafeez, BB1
Meske, L1
Verma, AK1
Sari, E1
Bakar, B1
Sarkarati, B1
Bozdogan, O1
Cavusoglu, T1
Goh, CF1
Craig, DQ1
Hadgraft, J1
Lane, ME1
Butawan, M1
Benjamin, RL1
Bloomer, RJ1
Colucci, M1
Maione, F1
Bonito, MC1
Piscopo, A1
Di Giannuario, A1
Pieretti, S1
Bernard, Y1
Melchior, C1
Tschirhart, E1
Bueb, JL1
Kim, YH1
Kim, DH1
Lim, H1
Baek, DY1
Shin, HK1
Kim, JK1
Kim, SL1
Kim, EM1
Cheong, SJ1
Lee, CM1
Kim, DW1
Jeong, HJ1
Lim, ST1
Sohn, MH1
Yim, CY1
Shi, J1
Lu, J1
Meng, G1
Zhu, H1
Hou, Y1
Yin, Y1
Zhao, S1
Ding, B1
Gierer, P1
Röther, J1
Mittlmeier, T1
Gradl, G1
Vollmar, B1
Kim, R1
Liu, W1
Chen, X1
Kreder, KJ1
Luo, Y1
Liang, J1
Xiao, G1
Ji, W1
Majtan, J1
Majtan, V1
Santos, NC1
Figueira-Coelho, J1
Martins-Silva, J1
Saldanha, C1
ROSENBAUM, EE3
JACOB, SW4
BISCHEL, M1
HERSCHLER, RJ2
Wentworth, P1
Nieva, J1
Takeuchi, C1
Galve, R1
Wentworth, AD1
Dilley, RB1
DeLaria, GA1
Saven, A1
Babior, BM1
Janda, KD1
Eschenmoser, A1
Lerner, RA1
Yatsushige, H1
Yamaguchi, M1
Zhou, C1
Calvert, JW1
Zhang, JH1
Pritchard, DI1
Todd, I1
Brown, A1
Bycroft, BW1
Chhabra, SR1
Williams, P1
Wood, P1
Zakaria, ZA2
Gopalan, HK2
Zainal, H1
Mohd Pojan, NH1
Morsid, NA1
Aris, A1
Sulaiman, MR2
Abdul Ghani, ZD1
Raden Mohd Nor, RN1
Abdullah, FC1
Björk, J1
del Maestro, RF1
Arfors, KE1
Biemond, P1
van Eijk, HG1
Swaak, AJ1
Koster, JF1
Parks, DA1
Bulkley, GB1
Granger, DN1
Kisilevsky, R1
Czuprynski, CJ1
Henson, PM1
Campbell, PA1
Alsup, EM1
DeBowes, RM1
Jimenez, RA1
Willkens, RF1
Francis, MD1
Horn, PA1
McCreary, LD1
Skosey, JL1
Herricks, RT1
Nordlund, JJ1
Ackles, AE1
Traynor, FF1
Schnyder, J1
Cooper, P1
MacKenzie, A1
Comas, D1
Mateu, J1
Schwiebert, LM1
Mooney, JL1
Van Horn, S1
Gupta, A1
Schleimer, RP1
Shi, MM1
Chong, IW1
Long, NC1
Love, JA1
Godleski, JJ1
Paulauskis, JD1
Trasciatti, S1
Podestà, A1
Bonaretti, S1
Mazzoncini, V1
Rosini, S1
Royals, MA1
Fujita, SM1
Yewey, GL1
Rodriguez, J1
Schultheiss, PC1
Dunn, RL1
Ohnishi, S1
Murata, M1
Kawanishi, S1
Hanna, C1
Fraunfelder, FT1
Meyer, SM1
Tsepov, LM1
Boĭko, NI1
Mejbaum-Katzenellenbogen, W1
Wróblewski, Z1
Kudrewicz-Hubicka, Z1
Lobodzińska, M1
Biernacka, I1
Skurska, Z1
Wood, DC1
Wood, J1
Senior, RM1
Skogen, WF1
Griffin, GL1
Wilner, GD1
Iwasa, F1
Galbraith, RA1
Sassa, S1
Frazer, GS1
Rossol, TJ1
Threlfall, WR1
Weisbrode, SE1
Marinkovic, D1
Zuyderhoudt, FM1
Goris, RJ1
Dongen, LM1
Winters, HA1
Brayton, CF1
Trice, JM1
Pinals, RS1
Teigland, MB1
Saurino, VR1
Mörsdorf, K2
Anspach, K1
Papadimitriou, JM1
Shilkin, KB1
Archer, JM1
Walters, MN1
Kamaev, MF1
Preziosi, P1
Scapagnini, U1
Görög, P2
Kovács, IB2
Creasey, NH1
Allenby, AC1
Schock, C1
Berliner, DL1
Ruhmann, AG1
Lerner, HJ1
Beckloff, G1
Arno, IC1
Wapner, PM1
Brownstein, IE1
Knowles, RP1
Steinberg, A1
Paul, MM1
Matsumoto, J1
von Ardenne, M1
Chaplain, RA1
Feit, J1
Buscher, H1
Oehlert, W1
Stone, OJ1
Willis, CJ1
Kumpmann, U1
Greaves, MW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Role of Vitamin c Supplementation in the Prevention of CRPS Following Distal Radius Fractures: a Randomized Control Study[NCT05842395]Phase 4220 participants (Anticipated)Interventional2023-06-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for dimethyl sulfoxide and Innate Inflammatory Response

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Embolization-induced angiogenesis in cerebral arteriovenous malformations.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:11

    Topics: Antigens, CD; Cell Hypoxia; Cerebrovascular Circulation; Combined Modality Therapy; Dimethyl Sulfoxi

2014
Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement.
    Nutrients, 2017, Mar-16, Volume: 9, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis; Biological Availability; Cartilage; Diet

2017
Multidisciplinary utilization of dimethyl sulfoxide: pharmacological, cellular, and molecular aspects.
    Biochemical pharmacology, 2003, Apr-01, Volume: 65, Issue:7

    Topics: Amyloidosis; Animals; Cell Differentiation; Cryopreservation; Dimethyl Sulfoxide; Humans; Inflammati

2003
Role of oxygen-derived free radicals in digestive tract diseases.
    Surgery, 1983, Volume: 94, Issue:3

    Topics: Allopurinol; Animals; Capillary Permeability; Cats; Digestive System Diseases; Dimethyl Sulfoxide; E

1983
Amyloidosis: a familiar problem in the light of current pathogenetic developments.
    Laboratory investigation; a journal of technical methods and pathology, 1983, Volume: 49, Issue:4

    Topics: Amino Acid Sequence; Amyloid; Amyloidosis; Animals; Blood Coagulation Disorders; Blood Physiological

1983
Dimethyl sulfoxide: a perspective of its use in rheumatic diseases.
    The Journal of laboratory and clinical medicine, 1982, Volume: 100, Issue:4

    Topics: Amyloidosis; Arthritis; Arthritis, Rheumatoid; Clinical Trials as Topic; Dimethyl Sulfoxide; Humans;

1982
Pharmacologic and biochemical considerations of dimethyl sulfoxide.
    Annals of the New York Academy of Sciences, 1975, Jan-27, Volume: 243

    Topics: Animals; Anti-Inflammatory Agents; Bacteria; Cats; Cholinesterase Inhibitors; Collagen; Dimethyl Sul

1975
Dimethyl sulfoxide (DMSO): a review.
    The Cornell veterinarian, 1986, Volume: 76, Issue:1

    Topics: Absorption; Administration, Topical; Analgesia; Animals; Blood Coagulation; Chemical and Drug Induce

1986
Dimethyl sulfoxide: a review of its use in the rheumatic disorders.
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:1

    Topics: Amyloidosis; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cell Division; Chemical Phenomena; Che

1985
[Antitrypsin activity of pentoxyl and dimethyl sulphoxide].
    Klinicheskaia meditsina, 1972, Volume: 50, Issue:7

    Topics: Adrenal Glands; Analgesics; Animals; Anti-Inflammatory Agents; Burns; Dimethyl Sulfoxide; Humans; In

1972

Trials

7 trials available for dimethyl sulfoxide and Innate Inflammatory Response

ArticleYear
The Effect of Daily Methylsulfonylmethane (MSM) Consumption on High-Density Lipoprotein Cholesterol in Healthy Overweight and Obese Adults: A Randomized Controlled Trial.
    Nutrients, 2021, Oct-15, Volume: 13, Issue:10

    Topics: Adult; Biomarkers; C-Reactive Protein; Cholesterol, HDL; Diet; Dimethyl Sulfoxide; Exercise; Female;

2021
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Dimethyl sulfoxide: a perspective of its use in rheumatic diseases.
    The Journal of laboratory and clinical medicine, 1982, Volume: 100, Issue:4

    Topics: Amyloidosis; Arthritis; Arthritis, Rheumatoid; Clinical Trials as Topic; Dimethyl Sulfoxide; Humans;

1982
Effects of dimethyl sulfoxide on ocular inflammation.
    Annals of ophthalmology, 1977, Volume: 9, Issue:1

    Topics: Acute Disease; Administration, Topical; Adult; Animals; Anti-Inflammatory Agents; Clinical Trials as

1977
[Experimental and clinical basis for the use of enzymatic and heparin electrophoresis in the overall therapy of localized forms of inflammation].
    Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury, 1979, Issue:3

    Topics: Animals; Chymotrypsin; Clinical Trials as Topic; Dimethyl Sulfoxide; Drug Evaluation; Drug Evaluatio

1979
Are toxic oxygen radicals involved in the pathogenesis of reflex sympathetic dystrophy?
    Free radical research communications, 1987, Volume: 3, Issue:1-5

    Topics: Adult; Aged; Aged, 80 and over; Dimethyl Sulfoxide; Female; Free Radicals; Humans; Inflammation; Mal

1987
Clinical trials of dimethyl sulfoxide in rheumatoid arthritis patients in Japan.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Dimethyl Sulfoxide; Edema; Female; Fever; Humans; I

1967

Other Studies

79 other studies available for dimethyl sulfoxide and Innate Inflammatory Response

ArticleYear
Methylsulfonylmethane ameliorates inflammation via NF-κB and ERK/JNK-MAPK signaling pathway in chicken trachea and HD11 cells during Mycoplasma gallisepticum infection.
    Poultry science, 2022, Volume: 101, Issue:4

    Topics: Animals; Chickens; Dimethyl Sulfoxide; Inflammation; JNK Mitogen-Activated Protein Kinases; Mycoplas

2022
Promoting mitochondrial fusion in doxorubicin-induced cardiotoxicity: a novel therapeutic target for cardioprotection.
    Clinical science (London, England : 1979), 2022, 06-17, Volume: 136, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Cardiotoxicity; Dimethyl Sulfoxide; Doxorubicin; In

2022
Responses of promyelocytic leukemia HL60 cells as an inflammatory cell lineage model to silica microparticles used to coat blood collection tubes.
    International journal of implant dentistry, 2022, 05-14, Volume: 8, Issue:1

    Topics: Animals; Cell Lineage; Dimethyl Sulfoxide; HL-60 Cells; Humans; Inflammation; Leukemia, Promyelocyti

2022
Therapeutic hypothermia alleviates myocardial ischaemia-reperfusion injury by inhibiting inflammation and fibrosis via the mediation of the SIRT3/NLRP3 signalling pathway.
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:19

    Topics: Animals; Apoptosis; Caspases; Collagen; Cytokines; Dimethyl Sulfoxide; Fibrosis; Hypothermia, Induce

2022
Montelukast induces beneficial behavioral outcomes and reduces inflammation in male and female rats.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Cyclopropanes; Depression; Dimet

2022
Sulfhydryl functionalized hyaluronic acid hydrogels attenuate cyclophosphamide-induced bladder injury.
    Biomedical materials (Bristol, England), 2022, 12-29, Volume: 18, Issue:1

    Topics: Animals; Cyclophosphamide; Cystitis; Dimethyl Sulfoxide; Hemorrhage; Hyaluronic Acid; Hydrogels; Inf

2022
Cigarette smoke-induced pulmonary impairment is associated with social recognition memory impairments and alterations in microglial profiles within the suprachiasmatic nucleus of the hypothalamus.
    Brain, behavior, and immunity, 2023, Volume: 109

    Topics: Adult; Animals; Cigarette Smoking; Dimethyl Sulfoxide; Humans; Hypothalamus; Inflammation; Lung; Mal

2023
Blockade of P2X7 receptor-mediated purinergic signaling with A438079 protects against LPS-induced liver injury in rats.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:10

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury, Chronic; Dimethyl Sulfoxide;

2023
Autophagy decreases alveolar epithelial cell injury by regulating the release of inflammatory mediators.
    Journal of cellular physiology, 2020, Volume: 235, Issue:11

    Topics: Alveolar Epithelial Cells; Animals; Autophagy; Cell Hypoxia; Dimethyl Sulfoxide; Disease Models, Ani

2020
Thiamine Deficiency Modulates p38
    Neurochemical research, 2020, Volume: 45, Issue:4

    Topics: Animals; Behavior, Animal; Body Weight; Brain; Cell Survival; Chromans; Dimethyl Sulfoxide; Eating;

2020
ERK is involved in the differentiation and function of dimethyl sulfoxide-induced HL-60 neutrophil-like cells, which mimic inflammatory neutrophils.
    International immunopharmacology, 2020, Volume: 84

    Topics: Animals; Cell Differentiation; Cytokines; Dimethyl Sulfoxide; Endocytosis; HL-60 Cells; Humans; Infl

2020
Sulfur Compounds Inhibit High Glucose-Induced Inflammation by Regulating NF-κB Signaling in Human Monocytes.
    Molecules (Basel, Switzerland), 2020, May-17, Volume: 25, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Dimethyl Sulfoxide; Gene Expression Regulatio

2020
Zinc Iodide in combination with Dimethyl Sulfoxide for treatment of SARS-CoV-2 and other viral infections.
    Medical hypotheses, 2020, Volume: 143

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Antiviral Agents; Betacoronavirus; Coronavirus Infe

2020
Modulatory role of hippocampal dopamine receptors in antinociceptive responses induced by chemical stimulation of the lateral hypothalamus in an animal model of persistent inflammatory pain.
    Brain research bulletin, 2020, Volume: 162

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; CA1 Region, Hippocampal; Dimethyl Sulfoxide; Disease

2020
Optimized Curcumin, Pomegranate Extract, and Methylsulfonylmethane Reduce Acute, Systemic Inflammatory Response to a Half-marathon Race.
    Alternative therapies in health and medicine, 2022, Volume: 28, Issue:6

    Topics: Biomarkers; Curcumin; Dietary Supplements; Dimethyl Sulfoxide; Female; Homosexuality, Male; Humans;

2022
[Protective effects of dimethyl sulfoxide on zymosan-insulted gut barrier impairment].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2017, Mar-08, Volume: 33, Issue:3

    Topics: Amine Oxidase (Copper-Containing); Animals; Cytokines; Dimethyl Sulfoxide; Inflammation; Intestinal

2017
Liver x receptor regulates arachidonic acid distribution and eicosanoid release in human macrophages: a key role for lysophosphatidylcholine acyltransferase 3.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:6

    Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Arachidonic Acid; Cells, Cultured; Dimethyl Sulfoxide

2013
Structural characterization and anti-inflammatory activity of a linear β-D-glucan isolated from Pleurotus sajor-caju.
    Carbohydrate polymers, 2014, Nov-26, Volume: 113

    Topics: Animals; Anti-Inflammatory Agents; beta-Glucans; Dimethyl Sulfoxide; Formaldehyde; Immunomodulation;

2014
Topically applied Hsp90 inhibitor 17AAG inhibits UVR-induced cutaneous squamous cell carcinomas.
    The Journal of investigative dermatology, 2015, Volume: 135, Issue:4

    Topics: Acetone; Animals; Benzoquinones; Dimethyl Sulfoxide; Epidermis; HSP90 Heat-Shock Proteins; Humans; I

2015
Effectiveness of Dimethylsulfoxide on the Survival and Volume Preservation of Autologous Fat Graft Tissue: A Preliminary Study.
    Aesthetic surgery journal, 2016, Volume: 36, Issue:2

    Topics: Adipose Tissue; Administration, Cutaneous; Angiogenesis Inducing Agents; Animals; Anti-Inflammatory

2016
The application of ATR-FTIR spectroscopy and multivariate data analysis to study drug crystallisation in the stratum corneum.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2017, Volume: 111

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Cluster Anal

2017
New insights of dimethyl sulphoxide effects (DMSO) on experimental in vivo models of nociception and inflammation.
    Pharmacological research, 2008, Volume: 57, Issue:6

    Topics: Administration, Oral; Animals; Anti-Infective Agents, Local; Dimethyl Sulfoxide; Edema; Formaldehyde

2008
Co-cultures of human coronary smooth muscle cells and dimethyl sulfoxide-differentiated HL60 cells upregulate ProMMP9 activity and promote mobility-modulation by reactive oxygen species.
    Inflammation, 2008, Volume: 31, Issue:5

    Topics: Antioxidants; Atherosclerosis; Cells, Cultured; Coculture Techniques; Dimethyl Sulfoxide; Gene Expre

2008
The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Cell Survival; Cytok

2009
The effect of PPAR-gamma agonist on (18)F-FDG uptake in tumor and macrophages and tumor cells.
    Nuclear medicine and biology, 2009, Volume: 36, Issue:4

    Topics: Animals; Biological Transport; Cell Line, Tumor; Dimethyl Sulfoxide; Fluorodeoxyglucose F18; Gene Ex

2009
Activation of peroxisome proliferator-activated receptor-gamma potentiates pro-inflammatory cytokine production, and adrenal and somatotropic changes of weaned pigs after Escherichia coli lipopolysaccharide challenge.
    Innate immunity, 2009, Volume: 15, Issue:3

    Topics: Animals; Benzhydryl Compounds; Cytokines; Dimethyl Sulfoxide; Dinoprostone; Epoxy Compounds; Escheri

2009
Ebselen reduces inflammation and microvascular perfusion failure after blunt skeletal muscle injury of the rat.
    The Journal of trauma, 2010, Volume: 68, Issue:4

    Topics: Analysis of Variance; Animals; Antioxidants; Azoles; Dimethyl Sulfoxide; Hindlimb; In Situ Nick-End

2010
Intravesical dimethyl sulfoxide inhibits acute and chronic bladder inflammation in transgenic experimental autoimmune cystitis models.
    Journal of biomedicine & biotechnology, 2011, Volume: 2011

    Topics: Acute Disease; Animals; Autoimmune Diseases; Chronic Disease; Cystitis; Dimethyl Sulfoxide; Disease

2011
Capsaicin induces reflex scratching in inflamed skin.
    Pharmacology, 2011, Volume: 88, Issue:1-2

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Capsaici

2011
Dimethyl sulfoxide attenuates TNF-α-induced production of MMP-9 in human keratinocytes.
    Journal of toxicology and environmental health. Part A, 2011, Volume: 74, Issue:20

    Topics: Cells, Cultured; Dimethyl Sulfoxide; Gene Expression Regulation, Enzymologic; Humans; Inflammation;

2011
DIMETHYL SULFOXIDE (DMSO) IN ACUTE MUSCULOSKELETAL INJURIES AND INFLAMMATIONS. I. DIMETHYL SULFOXIDE IN ACUTE SUBDELTOID BURSITIS.
    Northwest medicine, 1964, Volume: 63

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Bursitis; Dimethyl Sulfoxide; Humans; Inflammati

1964
DIMETHYL SULFOXIDE (DMSO): A NEW CONCEPT IN PHARMACOTHERAPY.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Infective Agents; Antipyretics; Dimethyl Sulfoxide; Diure

1964
DIMETHYL SULFOXIDE (DMSO) IN MUSCULOSKELETAL INJURIES AND INFLAMMATIONS. II. DIMETHYL SULFOXIDE IN RHEUMATOID ARTHRITIS, DEGENERATIVE ARTHRITIS AND GOUTY ARTHRITIS.
    Northwest medicine, 1964, Volume: 63

    Topics: Arthritis; Arthritis, Gouty; Arthritis, Rheumatoid; Dimethyl Sulfoxide; Gout; Humans; Inflammation;

1964
Evidence for ozone formation in human atherosclerotic arteries.
    Science (New York, N.Y.), 2003, Nov-07, Volume: 302, Issue:5647

    Topics: Arteriosclerosis; Carotid Arteries; Cholestanes; Cholesterol; Dimethyl Sulfoxide; Endarterectomy, Ca

2003
Role of c-Jun N-terminal kinase in cerebral vasospasm after experimental subarachnoid hemorrhage.
    Stroke, 2005, Volume: 36, Issue:7

    Topics: Angiography; Animals; Anthracenes; Blotting, Western; Cytokines; Dimethyl Sulfoxide; Dogs; Dose-Resp

2005
Alleviation of insulitis and moderation of diabetes in NOD mice following treatment with a synthetic Pseudomonas aeruginosa signal molecule, N-(3-oxododecanoyl)-L-homoserine lactone.
    Acta diabetologica, 2005, Volume: 42, Issue:3

    Topics: 4-Butyrolactone; Adjuvants, Immunologic; Animals; Diabetes Mellitus; Dimethyl Sulfoxide; Disease Mod

2005
Antinociceptive, anti-inflammatory and antipyretic effects of Solanum nigrum chloroform extract in animal models.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2006, Volume: 126, Issue:11

    Topics: Animals; Chloroform; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; E

2006
Antinociceptive and anti-inflammatory activities of Dicranopteris linearis leaves chloroform extract in experimental animals.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2006, Volume: 126, Issue:11

    Topics: Animals; Chloroform; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; E

2006
Evidence for participation of hydroxyl radical in increased microvascular permeability.
    Agents and actions. Supplements, 1980, Volume: 7

    Topics: Animals; Capillary Permeability; Catalase; Cricetinae; Dextrans; Dimethyl Sulfoxide; Free Radicals;

1980
Iron mobilization from ferritin by superoxide derived from stimulated polymorphonuclear leukocytes. Possible mechanism in inflammation diseases.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:6

    Topics: Animals; Catalase; Dimethyl Sulfoxide; Ferritins; Horses; Humans; Inflammation; Iron; Neutrophils; S

1984
Effect of dimethyl sulfoxide on the in vitro and in vivo bactericidal activity of human and mouse neutrophils and mononuclear phagocytes.
    Inflammation, 1984, Volume: 8, Issue:2

    Topics: Animals; Blood Bactericidal Activity; Dimethyl Sulfoxide; Escherichia coli; Humans; In Vitro Techniq

1984
Dimethyl sulfoxide.
    Journal of the American Veterinary Medical Association, 1984, Nov-01, Volume: 185, Issue:9

    Topics: Abnormalities, Drug-Induced; Analgesics; Animals; Anti-Infective Agents; Biological Transport; Centr

1984
Penetration and effect of topically applied dimethylsulfoxide or indomethacin on adjuvant arthritis in the rat.
    Arthritis and rheumatism, 1983, Volume: 26, Issue:7

    Topics: Administration, Topical; Animals; Arthritis; Arthritis, Experimental; Body Weight; Carbon Radioisoto

1983
DMSO: hope or hoax?
    Comprehensive therapy, 1980, Volume: 6, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Cystitis; Dimethyl Sulfoxide; Free Radicals; Humans; Inflammation

1980
DMSO, dimethylsulfoxide, an overview.
    Journal of the Medical Association of the State of Alabama, 1982, Volume: 51, Issue:7

    Topics: Animals; Dimethyl Sulfoxide; Guinea Pigs; Humans; Inflammation

1982
The proliferative and toxic effects of ultraviolet light and inflammation on epidermal pigment cells.
    The Journal of investigative dermatology, 1981, Volume: 77, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Cell Division; Dimethyl Sulfoxide; Epidermis; Indomethacin; Infla

1981
Modulation of secretory processes of phagocytes by IX 207-887.
    Springer seminars in immunopathology, 1993, Volume: 14, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cytokines; Dexamethasone; Dimethy

1993
Treatment of extravasation of both doxorubicin and vincristine administration in a Y-site infusion.
    The Annals of pharmacotherapy, 1996, Volume: 30, Issue:3

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protoc

1996
Identification of novel inducible genes in airway epithelium.
    American journal of respiratory cell and molecular biology, 1997, Volume: 17, Issue:1

    Topics: Base Sequence; Bronchi; Cell Line; Cloning, Molecular; Cytokines; Data Display; Dexamethasone; Dimet

1997
Functional characterization of recombinant rat macrophage inflammatory protein-1 alpha and mRNA expression in pulmonary inflammation.
    Inflammation, 1998, Volume: 22, Issue:1

    Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Cell Line; Chemokine CCL4; Chemotaxis, Leukoc

1998
In vitro effects of different formulations of bovine collagen on cultured human skin.
    Biomaterials, 1998, Volume: 19, Issue:10

    Topics: Achilles Tendon; Administration, Topical; Animals; Anti-Inflammatory Agents; Cattle; Cell Membrane;

1998
Biocompatibility of a biodegradable in situ forming implant system in rhesus monkeys.
    Journal of biomedical materials research, 1999, Jun-05, Volume: 45, Issue:3

    Topics: Animals; Behavior, Animal; Biocompatible Materials; Connective Tissue; Dimethyl Sulfoxide; Inflammat

1999
DNA damage induced by hypochlorite and hypobromite with reference to inflammation-associated carcinogenesis.
    Cancer letters, 2002, Apr-08, Volume: 178, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Bromates; Carcinogens; Cattle; Cell Line; Deoxyguanosine; Dime

2002
[Treatment of inflammatory infiltration with dimexide combined with antibiotics].
    Klinicheskaia khirurgiia, 1978, Issue:12

    Topics: Anti-Bacterial Agents; Appendectomy; Dimethyl Sulfoxide; Drug Therapy, Combination; Humans; Inflamma

1978
Rat interferons. IV. Sialoproteins in rat serum.
    Archivum immunologiae et therapiae experimentalis, 1977, Volume: 25, Issue:1

    Topics: Animals; Blood Proteins; Dimethyl Sulfoxide; Inflammation; Interferons; Newcastle disease virus; Oro

1977
Effects of fibrinogen derivatives upon the inflammatory response. Studies with human fibrinopeptide B.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:3

    Topics: Actins; Cell Aggregation; Cell Membrane; Cells, Cultured; Chemotaxis, Leukocyte; Complement C5; Comp

1986
Effects of dimethyl sulphoxide on the synthesis of plasma proteins in the human hepatoma HepG2. Induction of an acute-phase-like reaction.
    The Biochemical journal, 1988, Aug-01, Volume: 253, Issue:3

    Topics: Acute-Phase Reaction; Albumins; Animals; Blood Proteins; Cell Line; Dimethyl Sulfoxide; Humans; Infl

1988
Histopathologic effects of dimethyl sulfoxide on equine endometrium.
    American journal of veterinary research, 1988, Volume: 49, Issue:10

    Topics: Animals; Dimethyl Sulfoxide; Edema; Endometrium; Epithelium; Female; Fibrosis; Horses; Inflammation;

1988
Plasma lipid peroxides in murine sepsis--sex differences and effect of antioxidative/anti-inflammatory therapy.
    Free radical research communications, 1988, Volume: 4, Issue:4

    Topics: Animals; Bacterial Infections; Cecal Diseases; Chlorpromazine; Dimethyl Sulfoxide; Drug Therapy, Com

1988
Clinical evaluation of dimethyl sulfoxide in equine applications.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Animals; Bone Diseases; Dimethyl Sulfoxide; Edema; gamma-Globulins; Horses; Inflammation; Injections

1967
[Efficacy of different antiphlogistic agents with respect to carrageenan-inflammation, compared with other models of inflammation].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:1

    Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; D

1971
Inflammation induced by dimethylsulfoxide (DMSO). II. Ultrastructural investigation of the inflammatory phase.
    Experimental and molecular pathology, 1967, Volume: 6, Issue:3

    Topics: Albumins; Animals; Carbon; Dimethyl Sulfoxide; Globulins; Histamine H1 Antagonists; Inflammation; Le

1967
Action of dimethylsulfoxide on acute inflammatory reactions.
    Current therapeutic research, clinical and experimental, 1966, Volume: 8, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Dimethyl Sulfoxide; Edema; Inflammation; Rabbits; Rats

1966
Effect of dimethyl sulfoxide (DMSO) on various experimental inflammations.
    Current therapeutic research, clinical and experimental, 1968, Volume: 10, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Dimethyl Sulfoxide; Inflammation; Rats

1968
Ergotamine gangrene in various inflammatory conditions.
    Angiologica, 1971, Volume: 8, Issue:1

    Topics: Animals; Arthritis; Carrageenan; Collagen Diseases; Dextrans; Dimethyl Sulfoxide; Edema; Ergotamine;

1971
Mechanism of action of accelerants. The effect of cutaneously-applied penetration accelerants on the skin circulation of the rat.
    The British journal of dermatology, 1971, Volume: 85, Issue:4

    Topics: Amines; Animals; Capillary Permeability; Cold Temperature; Dimethyl Sulfoxide; Ear; Epinephrine; Fur

1971
The influence of dimethyl sulfoxide on fibroblastic proliferation.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Animals; Cattle; Cell Division; Culture Techniques; Dimethyl Sulfoxide; Drug Synergism; Fibroblasts;

1967
Effects of intravesical instillation of DMSO on the urinary bladder of the dog: preliminary report.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Absorption; Animals; Biopsy; Dimethyl Sulfoxide; Dogs; Edema; Inflammation; Male; Urinary Bladder; U

1967
Experiences with DMSO in relief of postpartum episiotomy pain.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Adult; Dimethyl Sulfoxide; Episiotomy; Female; Humans; Inflammation; Pain; Postoperative Care; Pregn

1967
Clinical experience with DMSO in small animal practice.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Animal Diseases; Animals; Animals, Domestic; Cats; Dimethyl Sulfoxide; Dog Diseases; Dogs; Edema; In

1967
The employment of dimethyl sulfoxide as an antiinflammatory agent and steroid-transporter in diversified clinical diseases.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Breast Neoplasms; Dimethyl Sulfoxide; Drug Synergism

1967
Interval therapy with dimethyl sulfoxide.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Adult; Aged; Arthritis; Bursitis; Diabetes Mellitus; Dimethyl Sulfoxide; Edema; Erythema Nodosum; Fe

1967
[In vivo experiments on the multistage cancer therapy with "triggering" attack by vitamin A plus dimethyl sulfoxide].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1969, Sep-15, Volume: 24, Issue:18

    Topics: Animals; Carcinoma, Ehrlich Tumor; Dimethyl Sulfoxide; Fever; Hydrogen-Ion Concentration; Inflammati

1969
[The distribution pattern and the length of stay of radioactively labeled carcinogenic hydrocarbons in the pigskin].
    Beitrage zur pathologischen Anatomie und zur allgemeinen Pathologie, 1967, Volume: 136, Issue:1

    Topics: Animals; Autoradiography; Benz(a)Anthracenes; Benzopyrenes; Cell Nucleus; Cytoplasm; Dimethyl Sulfox

1967
Chloroquine enhancement of inflammation.
    Texas reports on biology and medicine, 1968,Summer, Volume: 26, Issue:2

    Topics: Animals; Chloroquine; Dimethyl Sulfoxide; Inflammation; Phosphates; Pyridoxine; Rabbits; Skin

1968
[Experience report on the use of DMSO in general practice].
    Die Medizinische Welt, 1968, Feb-10, Volume: 6

    Topics: Adult; Dimethyl Sulfoxide; Female; Humans; Inflammation; Joint Diseases; Joints; Male; Middle Aged;

1968
The pharmacological basis for the rational use of topically applied corticosteroids.
    Pharmacology for physicians, 1969, Volume: 3, Issue:10

    Topics: Absorption; Administration, Topical; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Bradykinin;

1969
Dimethyl sulfoxide (DMSO): laboratory and clinical evaluation.
    Journal of the American Veterinary Medical Association, 1965, Dec-15, Volume: 147, Issue:12

    Topics: Adult; Aged; Analgesia; Animal Diseases; Animals; Bacteria; Burns; Collagen; Dimethyl Sulfoxide; Fem

1965
[A contribution to the pharmacology of dimethyl sulfoxide (DMSO)].
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 15, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Dextrans; Dimethyl Sulfoxide; Formaldehyde; Inflammation; Rats; T

1966