dimethyl sulfoxide has been researched along with Injuries, Spinal Cord in 22 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Naloxone has no effect on the clinical outcome but causes reasonable improvement electrophysiologically." | 5.27 | Effects of methyl prednisolone, dimethyl sulphoxide and naloxone in experimental spinal cord injuries in rats. ( Dalbasti, T; Ovül, I; Zileli, M, 1988) |
| " As matrix metalloproteinase-9 is likewise acutely elevated in dogs with naturally occurring spinal cord injuries, we evaluated efficacy of GM6001 solubilized in dimethyl sulfoxide in this second species." | 5.19 | Efficacy of a metalloproteinase inhibitor in spinal cord injured dogs. ( Cohen, ND; Fajt, VR; Fandel, TM; Heller, M; Kerwin, SC; Levine, GJ; Levine, JM; Modestino, A; Noble-Haeusslein, LJ; Trivedi, AA; Werb, Z, 2014) |
| "To ascertain the clinical significance of dimethyl sulfoxide-induced pigmenturia, we evaluated renal function and indicators of systemic hemolysis in stable quadriplegic patients receiving the drug intravenously (IV) for spinal cord injury." | 3.66 | Effects of dimethyl sulfoxide on renal function in man. ( Bennett, WM; Muther, RS, 1980) |
| "Dimethyl sulfoxide (DMSO) is a well-known hydroxyl radical scavenger, which is readily absorbed through biological membranes." | 1.30 | Failure of topical DMSO to improve blood flow or evoked potentials in rat spinal cord injury. ( Park, YK; Tator, CH, 1998) |
| "Dipyridamole and DMSO were administered daily for a period of 1 week." | 1.28 | Evaluation of drug effects on spinal cord injury--an experimental study in monkeys. ( Abraham, J; Chandy, M; Cherian, L; Kuruvilla, A, 1992) |
| "Naloxone has no effect on the clinical outcome but causes reasonable improvement electrophysiologically." | 1.27 | Effects of methyl prednisolone, dimethyl sulphoxide and naloxone in experimental spinal cord injuries in rats. ( Dalbasti, T; Ovül, I; Zileli, M, 1988) |
| "Acute spinal cord trauma was induced by the Allen method at T12 in 48 dogs." | 1.26 | Combined pharmacologic and surgical treatments for acute spinal cord trauma. ( Lumb, WV; Rucker, NC; Scott, RJ, 1981) |
| "Dimethyl sulfoxide has been tested in various experimental injuries of the central nervous system in relation to other therapies." | 1.25 | Dimethyl sulfoxide in central nervous system trauma. ( de la Torre, JC; Goode, DJ; Johnson, CM; Kajihara, K; Kawanaga, HM; Mullan, S, 1975) |
| "Permanent paralysis was induced in dogs by a 500 gram centimeter force injury on the spinal cord, and drug treatments were given 1 hour after injury and were continued for 3 days." | 1.25 | Pharmacologic treatment and evaluation of permanent experimental spinal cord trauma. ( De La Torre, JC; Goode, DJ; Johnson, CM; Mullan, S, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (63.64) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Abbaszadeh, F | 1 |
| Jorjani, M | 1 |
| Joghataei, MT | 1 |
| Mehrabi, S | 1 |
| Mi, X | 1 |
| Ni, C | 1 |
| Zhao, J | 1 |
| Amin, N | 1 |
| Jiao, D | 1 |
| Fang, M | 1 |
| Ye, X | 1 |
| Levine, JM | 1 |
| Cohen, ND | 1 |
| Heller, M | 1 |
| Fajt, VR | 1 |
| Levine, GJ | 1 |
| Kerwin, SC | 1 |
| Trivedi, AA | 1 |
| Fandel, TM | 1 |
| Werb, Z | 1 |
| Modestino, A | 1 |
| Noble-Haeusslein, LJ | 1 |
| Yamauchi, K | 1 |
| Osuka, K | 1 |
| Takayasu, M | 1 |
| Usuda, N | 1 |
| Nakazawa, A | 1 |
| Nakahara, N | 1 |
| Yoshida, M | 1 |
| Aoshima, C | 1 |
| Hara, M | 1 |
| Yoshida, J | 1 |
| Goldsmith, HS | 1 |
| Goodnough, J | 1 |
| Allen, N | 1 |
| Nesham, ME | 1 |
| Clendenon, NR | 1 |
| Rucker, NC | 2 |
| Lumb, WV | 2 |
| Scott, RJ | 2 |
| Hill, PK | 1 |
| de la Torre, JC | 4 |
| Thompson, SM | 1 |
| Rosenfield-Wessels, S | 1 |
| Beckett, ML | 1 |
| Gelderd, JB | 2 |
| Fife, WP | 2 |
| Bowers, DE | 2 |
| Deschner, SH | 1 |
| Welch, DW | 2 |
| Cottrell, JE | 1 |
| Muther, RS | 1 |
| Bennett, WM | 1 |
| Park, YK | 1 |
| Tator, CH | 1 |
| Thomas, AJ | 1 |
| Nockels, RP | 1 |
| Pan, HQ | 1 |
| Shaffrey, CI | 1 |
| Chopp, M | 1 |
| Parker, AJ | 1 |
| Smith, CW | 1 |
| Kawanaga, HM | 1 |
| Johnson, CM | 2 |
| Goode, DJ | 2 |
| Kajihara, K | 2 |
| Mullan, S | 3 |
| Cherian, L | 1 |
| Kuruvilla, A | 1 |
| Abraham, J | 1 |
| Chandy, M | 1 |
| Zileli, M | 1 |
| Ovül, I | 1 |
| Dalbasti, T | 1 |
| Heymann, LD | 1 |
| Kawanaga, H | 1 |
1 review available for dimethyl sulfoxide and Injuries, Spinal Cord
| Article | Year |
|---|---|
Anesthesia for neurosurgery.
Topics: Anesthesia, General; Blood Pressure; Brain; Central Nervous System; Cerebrovascular Circulation; Dim | 1982 |
1 trial available for dimethyl sulfoxide and Injuries, Spinal Cord
| Article | Year |
|---|---|
Efficacy of a metalloproteinase inhibitor in spinal cord injured dogs.
Topics: Animals; Dimethyl Sulfoxide; Dipeptides; Dog Diseases; Dogs; Double-Blind Method; Drug Therapy, Comb | 2014 |
20 other studies available for dimethyl sulfoxide and Injuries, Spinal Cord
| Article | Year |
|---|---|
Astaxanthin Modulates Autophagy, Apoptosis, and Neuronal Oxidative Stress in a Rat Model of Compression Spinal Cord Injury.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; bcl-2-Associated X Protein; Beclin-1; Dimethyl Sulfoxid | 2022 |
P2Y12 receptor mediates apoptosis and demyelination to affect functional recovery in mice with spinal cord injury.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Calbindins; Demyelinating Diseases; Dimethyl Sulfoxi | 2023 |
Activation of JAK/STAT signalling in neurons following spinal cord injury in mice.
Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Enzyme Inhibitors; Female; Janus Kinase 1; Mice | 2006 |
Can the standard treatment of acute spinal cord injury be improved? Perhaps the time has come.
Topics: Acute Disease; Animals; Cats; Cicatrix; Dimethyl Sulfoxide; Dura Mater; Edema; Humans; Neuroprotecti | 2007 |
The effect of dimethyl sulfoxide on gray matter injury in experimental spinal cord trauma.
Topics: Animals; Brain Edema; Culture Techniques; Dimethyl Sulfoxide; Dogs; Electron Transport Complex IV; F | 1980 |
Combined pharmacologic and surgical treatments for acute spinal cord trauma.
Topics: Animals; Dexamethasone; Dimethyl Sulfoxide; Dogs; Female; Male; Perfusion; Prognosis; Reserpine; Spi | 1983 |
Ultrastructural studies of rat fasciculi gracilis unmyelinated fibers after contusion and DMSO treatment.
Topics: Animals; Dimethyl Sulfoxide; Female; Nerve Fibers; Rats; Rats, Inbred Strains; Spinal Cord; Spinal C | 1983 |
Spinal cord transection in rats: the therapeutic effects of dimethyl sulfoxide and hyperbaric oxygen.
Topics: Animals; Dimethyl Sulfoxide; Hyperbaric Oxygenation; Rats; Spinal Cord Injuries; Trypsin | 1983 |
Effects of dimethyl sulfoxide on renal function in man.
Topics: Adolescent; Adult; Brain Edema; Dimethyl Sulfoxide; Female; Hemoglobinuria; Hemolysis; Humans; Kidne | 1980 |
Therapeutic effects of hyperbaric oxygen and dimethyl sulfoxide following spinal cord transections in rats.
Topics: Animals; Dimethyl Sulfoxide; Hyperbaric Oxygenation; Male; Rats; Spinal Cord; Spinal Cord Injuries | 1980 |
Combined pharmacologic and surgical treatments for acute spinal cord trauma.
Topics: Acute Disease; Animals; Dexamethasone; Dimethyl Sulfoxide; Dog Diseases; Dogs; Female; Glucose; Male | 1981 |
Failure of topical DMSO to improve blood flow or evoked potentials in rat spinal cord injury.
Topics: Administration, Topical; Animals; Blood Pressure; Carbon Dioxide; Dimethyl Sulfoxide; Evoked Potenti | 1998 |
Progesterone is neuroprotective after acute experimental spinal cord trauma in rats.
Topics: Acute Disease; Analgesics, Non-Narcotic; Animals; Dimethyl Sulfoxide; Disease Models, Animal; Drug T | 1999 |
Lack of functional recovery from spinal cord trauma following dimethylsulphoxide and epsilon amino caproic acid therapy in dogs.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Dimethyl Sulfoxide; Dog Diseases; Dogs; Spinal Cord Inju | 1979 |
Dimethyl sulfoxide in central nervous system trauma.
Topics: Animals; Brain; Brain Injuries; Cerebral Arteries; Craniocerebral Trauma; Dimethyl Sulfoxide; Female | 1975 |
Pharmacologic treatment and evaluation of permanent experimental spinal cord trauma.
Topics: Animals; Dexamethasone; Dimethyl Sulfoxide; Dogs; Electric Stimulation; Evoked Potentials; Female; I | 1975 |
Evaluation of drug effects on spinal cord injury--an experimental study in monkeys.
Topics: Animals; Dimethyl Sulfoxide; Dipyridamole; Drug Evaluation, Preclinical; Female; Macaca radiata; Mal | 1992 |
Effects of methyl prednisolone, dimethyl sulphoxide and naloxone in experimental spinal cord injuries in rats.
Topics: Action Potentials; Animals; Dimethyl Sulfoxide; Naloxone; Prednisolone; Rats; Spinal Cord Injuries; | 1988 |
Dimethyl sulfoxide.
Topics: Animals; Dimethyl Sulfoxide; Dog Diseases; Dogs; Spinal Cord Injuries | 1986 |
Dimethyl sulfoxide in the treatment of experimental acute spinal cord injury.
Topics: Animals; Dexamethasone; Dimethyl Sulfoxide; Disease Models, Animal; Dogs; Drug Synergism; Evaluation | 1973 |