Page last updated: 2024-10-18

dimethyl sulfoxide and Hyperplasia

dimethyl sulfoxide has been researched along with Hyperplasia in 13 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"This study demonstrates that local short-term treatment with TKI produces a 49% reduction in intimal hyperplasia and suggests that phosphorylation of tyrosine residues is involved in the signaling pathways leading to the development of intimal hyperplasia in vein grafts."7.70Local inhibition of tyrosine kinase activity markedly attenuates the development of intimal hyperplasia in experimental vein grafts. ( Barber, L; Davies, MG; Hagen, PO; Huynh, TT; Svendsen, E, 1998)
"Intimal hyperplasia was measured as the ratio of the absolute area of intimal hyperplasia to the normalized area enclosed by the internal elastic lamina (IH/IEL) and was expressed as a percent."5.29Suppression of intimal hyperplasia in a rabbit model of arterial balloon injury by enalaprilat but not dimethyl sulfoxide. ( Colburn, MD; Gelabert, HA; Hajjar, GE; Law, MM; Moore, WS; Quiñones-Baldrich, WJ, 1994)
"This study demonstrates that local short-term treatment with TKI produces a 49% reduction in intimal hyperplasia and suggests that phosphorylation of tyrosine residues is involved in the signaling pathways leading to the development of intimal hyperplasia in vein grafts."3.70Local inhibition of tyrosine kinase activity markedly attenuates the development of intimal hyperplasia in experimental vein grafts. ( Barber, L; Davies, MG; Hagen, PO; Huynh, TT; Svendsen, E, 1998)
"Epirubicin fluorescence was observed in the entire bladder wall of normal or hyperplastic regions in rats that were given DMSO prior to epirubicin."1.30Transmurally absorbed intravesical chemotherapy with dimethylsulfoxide in an animal model. ( Göğüş, O; Ozdiler, E; Sözen, S; Yaman, O, 1999)
"Intimal hyperplasia was measured as the ratio of the absolute area of intimal hyperplasia to the normalized area enclosed by the internal elastic lamina (IH/IEL) and was expressed as a percent."1.29Suppression of intimal hyperplasia in a rabbit model of arterial balloon injury by enalaprilat but not dimethyl sulfoxide. ( Colburn, MD; Gelabert, HA; Hajjar, GE; Law, MM; Moore, WS; Quiñones-Baldrich, WJ, 1994)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's6 (46.15)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Li, YP1
Qiang, TT1
Wang, KY1
Wang, XL1
Setälä, K1
Law, MM1
Colburn, MD1
Hajjar, GE1
Gelabert, HA1
Quiñones-Baldrich, WJ1
Moore, WS1
Huynh, TT1
Davies, MG1
Barber, L1
Svendsen, E1
Hagen, PO1
Yaman, O1
Ozdiler, E1
Sözen, S1
Göğüş, O1
Darmer, KI1
DiGiovanni, J1
Stevenson, DE1
Gill, RD1
Ewing, MW1
Ismail, AA1
Burr, WA1
Taylor, NF1
Walker, PL1
Ito, M1
Ikeda, K1
Yokoyama, H1
Motoyoshi, K1
Sato, Y1
Hashimoto, K1
Rutten, AA1
Beems, RB1
Wilmer, JW1
Weirich, EG1
Longauer, J1
Kempff, PG1
Pitout, MH1
van der Watt, JJ1
Schrek, R1
Rappaport, H1
Rubnitz, ME1
Kwaan, HC1
Metsälä, P1

Other Studies

13 other studies available for dimethyl sulfoxide and Hyperplasia

ArticleYear
Shexiang Baoxin Pill Regulates Intimal Hyperplasia, Migration, and Apoptosis after Platelet-Derived Growth Factor-BB-Stimulation of Vascular Smooth Muscle Cells via miR-451.
    Chinese journal of integrative medicine, 2022, Volume: 28, Issue:9

    Topics: Apoptosis; Becaplermin; Cell Movement; Cell Proliferation; Cells, Cultured; Dimethyl Sulfoxide; Drug

2022
A new suggestion of the design of rational anticancer therapy: experimental studies in mice.
    Medical hypotheses, 1982, Volume: 8, Issue:3

    Topics: Animals; Cell Differentiation; Colchicine; Cytoplasm; Dimethyl Sulfoxide; Dose-Response Relationship

1982
Suppression of intimal hyperplasia in a rabbit model of arterial balloon injury by enalaprilat but not dimethyl sulfoxide.
    Annals of vascular surgery, 1994, Volume: 8, Issue:2

    Topics: Angioplasty, Balloon; Animals; Carotid Artery Injuries; Carotid Artery, Common; Dimethyl Sulfoxide;

1994
Local inhibition of tyrosine kinase activity markedly attenuates the development of intimal hyperplasia in experimental vein grafts.
    The Journal of surgical research, 1998, Jul-01, Volume: 77, Issue:2

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Bradykinin; Dimethyl Sulfoxide; DNA; Enz

1998
Transmurally absorbed intravesical chemotherapy with dimethylsulfoxide in an animal model.
    International journal of urology : official journal of the Japanese Urological Association, 1999, Volume: 6, Issue:2

    Topics: Administration, Intravesical; Animals; Antibiotics, Antineoplastic; Carcinogens; Dimethyl Sulfoxide;

1999
Evaluation of sustained hyperplasia and other short-term tests as predictors of tumorigenic potential in oil products.
    Progress in clinical and biological research, 1992, Volume: 374

    Topics: Animals; Carcinogens; Cell Nucleus; CHO Cells; Cricetinae; Dimethyl Sulfoxide; DNA; DNA Replication;

1992
Elevated plasma adrenocorticotropin (ACTH) with adrenal hyperplasia: a new factor in ACTH regulation?
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 73, Issue:4

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Cortodoxone; Cushing Syndrome; Dimethyl Sulfoxid

1991
Stereographic and stereometric study of sebaceous gland hyperplasia in rabbit pinnas induced by topically applied substances.
    The Journal of investigative dermatology, 1991, Volume: 97, Issue:1

    Topics: Administration, Topical; Alkanes; Animals; Dimethyl Sulfoxide; Ear, External; Hyperplasia; Male; Rab

1991
Effects of all-trans retinol and cigarette smoke condensate on hamster tracheal epithelium in organ culture. II. A histomorphological study.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1988, Volume: 55, Issue:3

    Topics: Animals; Cell Differentiation; Cricetinae; Dimethyl Sulfoxide; Drug Interactions; Epithelium; Hyperp

1988
Inhibition of sebaceous glands by topical application of oestrogen and anti-androgen on the auricular skin of rabbits. Histometric studies of the activity of the sebaceous glands.
    Archiv fur dermatologische Forschung, 1974, Volume: 250, Issue:2

    Topics: Acne Vulgaris; Administration, Topical; Androgen Antagonists; Animals; Castration; Dimethyl Sulfoxid

1974
The long-term influence of sterigmatocystin on mouse and rat liver nuclear deoxyribonucleases.
    Biochemical pharmacology, 1973, Oct-01, Volume: 22, Issue:19

    Topics: Animals; Carcinogens; Cell Nucleus; Deoxyribonucleases; Dimethyl Sulfoxide; Furans; Hyperplasia; In

1973
Cytology and reactions of viable cells from malignant lymphoma.
    Cancer, 1969, Volume: 23, Issue:5

    Topics: Adult; Aged; Asparaginase; Cell Differentiation; Cell Transformation, Neoplastic; Dimethyl Sulfoxide

1969
Effect of dimethyl sulfoxide (DMSO) on cytoplasmic barrier of malignant epidermal cells. An investigation in skin-tumor-resistant mice.
    Acta radiologica. Supplementum, 1971, Volume: 307

    Topics: Animals; Benz(a)Anthracenes; Colchicine; Dimethyl Sulfoxide; Female; Hyperplasia; Mice; Skin; Surfac

1971