Page last updated: 2024-10-18

dimethyl sulfoxide and Herpes Zoster

dimethyl sulfoxide has been researched along with Herpes Zoster in 28 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Herpes Zoster: An acute infectious, usually self-limited, disease believed to represent activation of latent varicella-zoster virus (HERPESVIRUS 3, HUMAN) in those who have been rendered partially immune after a previous attack of CHICKENPOX. It involves the SENSORY GANGLIA and their areas of innervation and is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. (From Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Both topical 40% idoxuridine in dimethylsulfoxide (IDU) and oral acyclovir (ACV) are useful in herpes zoster (HZ)."9.07[A topical solution of 40% idoxuridine in dimethyl sulfoxide compared to oral acyclovir in the treatment of herpes zoster. A double-blind multicenter clinical trial]. ( Aliaga, A; Armijo, M; Camacho, F; Castro, A; Cruces, M; Díaz, JL; Fernández, JM; Iglesias, L; Ledo, A; Mascaró, JM, 1992)
"A double-blind, random selection comparison was made of the therapeutic effects in acute herpes zoster of (A) 40% idoxuridine (IDU) dissolved in dimethyl sulphoxide (DMSO), or one of the following ointments: (B) a basis of polyethylene glycol, (C) a basis with 60% DMSO, (D) a basis with 5% IDU and 60% DMSO, and (E) a basis with 40% IDU and 60% DMSO."9.04Treatment of herpes zoster with idoxuridine ointment, including a multivariate analysis of symptoms and signs. ( Esmann, V; Ingemann-Jensen, J; Ipsen, J; Poulsen, JH; Wildenhoff, KE, 1979)
"An uncontrolled, double-blind, random-selection study of fifty consecutive patients with attacks of herpes zoster treated with one of two concentrations (5 per cent or 40 per cent) of idoxuridine (IDU) in dimethyl sulphoxide (DMSO) has shown that, over all, the patients fared better than would have been expected had they been treated only symptomatically."9.04Idoxuridine in the treatment of herpes zoster. ( Simpson, JR, 1975)
"In a randomized double-blind controlled trial of the value of intermittent topical idoxuridine in treating herpes zoster in 118 patients idoxuridine 5% in 100% dimethyl sulphoxide (DMSO), applied four-hourly for four days, significantly shortened the vesicular phase, healing time, and duration of pain; idoxuridine 25% applied two-hourly produced no greater benefit."9.04Idoxuridine in herpes zoster: further evaluation of intermittent topical therapy. ( Dawber, R, 1974)
"Both topical 40% idoxuridine in dimethylsulfoxide (IDU) and oral acyclovir (ACV) are useful in herpes zoster (HZ)."5.07[A topical solution of 40% idoxuridine in dimethyl sulfoxide compared to oral acyclovir in the treatment of herpes zoster. A double-blind multicenter clinical trial]. ( Aliaga, A; Armijo, M; Camacho, F; Castro, A; Cruces, M; Díaz, JL; Fernández, JM; Iglesias, L; Ledo, A; Mascaró, JM, 1992)
"A double-blind, random selection comparison was made of the therapeutic effects in acute herpes zoster of (A) 40% idoxuridine (IDU) dissolved in dimethyl sulphoxide (DMSO), or one of the following ointments: (B) a basis of polyethylene glycol, (C) a basis with 60% DMSO, (D) a basis with 5% IDU and 60% DMSO, and (E) a basis with 40% IDU and 60% DMSO."5.04Treatment of herpes zoster with idoxuridine ointment, including a multivariate analysis of symptoms and signs. ( Esmann, V; Ingemann-Jensen, J; Ipsen, J; Poulsen, JH; Wildenhoff, KE, 1979)
"An uncontrolled, double-blind, random-selection study of fifty consecutive patients with attacks of herpes zoster treated with one of two concentrations (5 per cent or 40 per cent) of idoxuridine (IDU) in dimethyl sulphoxide (DMSO) has shown that, over all, the patients fared better than would have been expected had they been treated only symptomatically."5.04Idoxuridine in the treatment of herpes zoster. ( Simpson, JR, 1975)
"In a randomized double-blind controlled trial of the value of intermittent topical idoxuridine in treating herpes zoster in 118 patients idoxuridine 5% in 100% dimethyl sulphoxide (DMSO), applied four-hourly for four days, significantly shortened the vesicular phase, healing time, and duration of pain; idoxuridine 25% applied two-hourly produced no greater benefit."5.04Idoxuridine in herpes zoster: further evaluation of intermittent topical therapy. ( Dawber, R, 1974)
"Twenty-two patients with Herpes Simplex were treated with Betadine (povidone iodine) Antiseptic paint and seven with 5% idoxuridine in dimethyl sulphoxide, also one patient with bilateral lesions was treated with the two solutions, one on each side."3.65The use of betadine antiseptic paint in the treatment of Herpes simplex and Herpes Zoster. ( Woodbridge, P, 1977)
"Dimethyl sulfoxide (DMSO) is a molecule with a long history in pharmaceutics and is now well established as a penetration enhancer in topical pharmaceutical formulations."2.47Dimethyl sulfoxide: an effective penetration enhancer for topical administration of NSAIDs. ( Marren, K, 2011)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199026 (92.86)18.7374
1990's1 (3.57)18.2507
2000's0 (0.00)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Marren, K1
Burton, WJ1
Gould, PW1
Hursthouse, MW1
Sears, PJ1
Larnder, DA1
Stringer, HC2
Turnbull, BC2
Thiers, BH1
Zaĭtsev, RZ1
Orekhov, EG1
Shtabtsov, VI1
Reichhart, W1
Haas, LF1
Dawber, RP1
Wildenhoff, KE1
Ipsen, J1
Esmann, V1
Ingemann-Jensen, J1
Poulsen, JH1
Verbov, J1
Juel-Jensen, B1
Grushkov, VM1
Todoriv, VD1
Woodbridge, P1
Nasemann, Th1
Sehtman, L1
Simpson, JR2
Aliaga, A1
Armijo, M1
Camacho, F1
Castro, A1
Cruces, M1
Díaz, JL1
Fernández, JM1
Iglesias, L1
Ledo, A1
Mascaró, JM1
Loeser, JD1
Nasemann, T1
Walther, H1
Juel-Jensen, BE2
Dawber, R1
MacCallum, FO1
Mackenzie, AM1
Pike, MC1
MacGregor, I1
Weitgasser, H1

Reviews

3 reviews available for dimethyl sulfoxide and Herpes Zoster

ArticleYear
Dimethyl sulfoxide: an effective penetration enhancer for topical administration of NSAIDs.
    The Physician and sportsmedicine, 2011, Volume: 39, Issue:3

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Dimethyl Sulfoxide; Drug Delivery

2011
Herpes zoster and postherpetic neuralgia.
    Pain, 1986, Volume: 25, Issue:2

    Topics: Acyclovir; Adenosine Monophosphate; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anesthetics, L

1986
[On the therapy of skin and veneral diseases. Review of the literature 1965-66].
    Deutsches medizinisches Journal, 1968, Mar-20, Volume: 19, Issue:6

    Topics: Adult; Allantoin; Chloramphenicol; Cortisone; Dimethyl Sulfoxide; Erectile Dysfunction; Frostbite; H

1968

Trials

6 trials available for dimethyl sulfoxide and Herpes Zoster

ArticleYear
A multicentre trial of Zostrum (5 percent idoxuridine in dimethyl sulphoxide) in herpes zoster.
    The New Zealand medical journal, 1981, Nov-25, Volume: 94, Issue:696

    Topics: Administration, Topical; Analgesics; Clinical Trials as Topic; Dimethyl Sulfoxide; Drug Eruptions; H

1981
Treatment of herpes zoster with idoxuridine ointment, including a multivariate analysis of symptoms and signs.
    Scandinavian journal of infectious diseases, 1979, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Analysis of Variance; Child; Clinical Trials as Topic; Dimethy

1979
Idoxuridine in the treatment of herpes zoster.
    The Practitioner, 1975, Volume: 215, Issue:1286

    Topics: Administration, Topical; Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Dimethyl Sulfoxid

1975
[A topical solution of 40% idoxuridine in dimethyl sulfoxide compared to oral acyclovir in the treatment of herpes zoster. A double-blind multicenter clinical trial].
    Medicina clinica, 1992, Feb-22, Volume: 98, Issue:7

    Topics: Acyclovir; Administration, Oral; Administration, Topical; Adult; Dimethyl Sulfoxide; Double-Blind Me

1992
Idoxuridine in herpes zoster: further evaluation of intermittent topical therapy.
    British medical journal, 1974, Jun-08, Volume: 2, Issue:5918

    Topics: Administration, Topical; Blood Cell Count; Clinical Trials as Topic; Dimethyl Sulfoxide; Erythema; H

1974
Treatment of zoster with idoxuridine in dimethyl sulphoxide. Results of two double-blind controlled trials.
    British medical journal, 1970, Dec-26, Volume: 4, Issue:5738

    Topics: Adult; Aged; Blood Cell Count; Child; Clinical Trials as Topic; Dimethyl Sulfoxide; Dosage Forms; Fe

1970

Other Studies

19 other studies available for dimethyl sulfoxide and Herpes Zoster

ArticleYear
Unusual treatments for herpesvirus infections. II. Herpes zoster.
    Journal of the American Academy of Dermatology, 1983, Volume: 8, Issue:3

    Topics: Acyclovir; Antiviral Agents; Dimethyl Sulfoxide; Double-Blind Method; Griseofulvin; Herpes Zoster; H

1983
[Clinical and treatment characteristics of herpes zoster].
    Voenno-meditsinskii zhurnal, 1982, Issue:6

    Topics: Aged; Dimethyl Sulfoxide; Drug Therapy, Combination; Herpes Zoster; Humans; Methods; Middle Aged

1982
[Results of a field study using idoxuridine in dimethylsulfoxide in the treatment of herpes zoster and herpes simplex].
    Zeitschrift fur Hautkrankheiten, 1980, Jun-15, Volume: 55, Issue:12

    Topics: Dimethyl Sulfoxide; Drug Combinations; Female; Herpes Simplex; Herpes Zoster; Humans; Idoxuridine; M

1980
Post-herpetic neuralgia, treatment and prevention.
    Transactions of the Ophthalmological Society of New Zealand, 1977, Volume: 29

    Topics: Dimethyl Sulfoxide; Electric Stimulation; Herpes Zoster; Humans; Idoxuridine; Neuralgia

1977
Development and therapeutic uses of topical 5% idoxuridine (IDU).
    Scottish medical journal, 1977, Volume: 22, Issue:4

    Topics: Administration, Topical; Chronic Disease; Dimethyl Sulfoxide; Herpes Simplex; Herpes Zoster; History

1977
Local idoxuridine treatment of herpes simplex and zoster.
    The Journal of antimicrobial chemotherapy, 1979, Volume: 5, Issue:2

    Topics: Administration, Topical; Dimethyl Sulfoxide; Eczema; Erythema Multiforme; Herpes Simplex; Herpes Zos

1979
Shingles: a belt of roses from Hell.
    British medical journal, 1979, Mar-24, Volume: 1, Issue:6166

    Topics: Dimethyl Sulfoxide; Drug Combinations; Herpes Zoster; Humans; Idoxuridine

1979
[Treatment of herpes zoster with dimethyl sulfoxide].
    Vrachebnoe delo, 1978, Issue:1

    Topics: Administration, Topical; Dimethyl Sulfoxide; Female; Herpes Zoster; Humans; Male; Middle Aged

1978
The use of betadine antiseptic paint in the treatment of Herpes simplex and Herpes Zoster.
    The Journal of international medical research, 1977, Volume: 5, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dimethyl Sulfoxide; Female; Herpes Simplex; Herpes

1977
[Combination of IDU and DMSO in zoster?].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1976, Volume: 27, Issue:9

    Topics: Dimethyl Sulfoxide; Drug Therapy, Combination; Herpes Zoster; Humans; Idoxuridine

1976
Dimethyl sulfoxide therapy in various dermatological disorders.
    Annals of the New York Academy of Sciences, 1975, Jan-27, Volume: 243

    Topics: Dimethyl Sulfoxide; Female; Herpes Zoster; Humans; Impetigo; Male; Nails, Ingrown; Pityriasis; Skin

1975
Drugs for herpes zoster.
    Drug and therapeutics bulletin, 1975, Feb-14, Volume: 13, Issue:4

    Topics: Adrenal Cortex Hormones; Amantadine; Cytarabine; Dimethyl Sulfoxide; Herpes Zoster; Humans; Idoxurid

1975
[Therapy of herpes simplex and herpes zoster].
    Archiv fur dermatologische Forschung, 1972, Volume: 244

    Topics: Adrenal Cortex Hormones; Dimethyl Sulfoxide; gamma-Globulins; Herpes Simplex; Herpes Zoster; Herpes

1972
Herpes simplex and zoster.
    British medical journal, 1973, Feb-17, Volume: 1, Issue:5850

    Topics: Age Factors; Central Nervous System Diseases; Conjunctivitis; Cytarabine; Dimethyl Sulfoxide; Eczema

1973
Herpes simplex and zoster.
    British medical journal, 1973, Mar-31, Volume: 1, Issue:5856

    Topics: Adrenocorticotropic Hormone; Aged; Dimethyl Sulfoxide; Herpes Simplex; Herpes Zoster; Humans; Pain

1973
Letter: Idoxuridine in herpes zoster.
    British medical journal, 1974, Aug-24, Volume: 3, Issue:5929

    Topics: Administration, Topical; Aged; Child; Dimethyl Sulfoxide; Drug Hypersensitivity; Herpes Zoster; Huma

1974
Herpes simplex and zoster.
    British medical journal, 1973, Mar-24, Volume: 1, Issue:5855

    Topics: Cicatrix; Dimethyl Sulfoxide; Herpes Simplex; Herpes Zoster; Humans; Idoxuridine; Skin Diseases

1973
The enhancing effect of dimethylsulfoxide vehicle upon the anti-viral actions of 5-iododeoxyuridine.
    The New Zealand medical journal, 1969, Volume: 70, Issue:450

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dimethyl Sulfoxide; Female; Herpes Simplex; Herpes

1969
[Dermatological experience with dimethyl sulfoxide (DMSO)].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1967, Sep-15, Volume: 42, Issue:18

    Topics: Dimethyl Sulfoxide; Dupuytren Contracture; Female; Fibroma; Granuloma; Herpes Zoster; Humans; Keloid

1967