Compounds > dimethyl sulfoxide
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dimethyl sulfoxide and Herpes Simplex Virus Infection

dimethyl sulfoxide has been researched along with Herpes Simplex Virus Infection in 34 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Research Excerpts

ExcerptRelevanceReference
"In search of new potent treatment of herpes simplex keratitis (HSK), inhibitory effect of oridonin (Ori) on herpes simplex virus type 1 (HSV-1) was validated by experiments."8.12Antiviral Activity of Oridonin Against Herpes Simplex Virus Type 1. ( Feng, J; Jiang, K; Qi, X; Ran, L; Xie, L, 2022)
"In search of new potent treatment of herpes simplex keratitis (HSK), inhibitory effect of oridonin (Ori) on herpes simplex virus type 1 (HSV-1) was validated by experiments."4.12Antiviral Activity of Oridonin Against Herpes Simplex Virus Type 1. ( Feng, J; Jiang, K; Qi, X; Ran, L; Xie, L, 2022)
"Twenty-two patients with Herpes Simplex were treated with Betadine (povidone iodine) Antiseptic paint and seven with 5% idoxuridine in dimethyl sulphoxide, also one patient with bilateral lesions was treated with the two solutions, one on each side."3.65The use of betadine antiseptic paint in the treatment of Herpes simplex and Herpes Zoster. ( Woodbridge, P, 1977)
" We also studied the relationship between the clinical efficacy of different dosing frequencies and the amount of IDU in the stratum corneum."1.27Measurement of the stratum corneum drug reservoir to predict the therapeutic efficacy of topical iododeoxyuridine for herpes simplex virus infection. ( McKeough, MB; Sheth, NV; Spruance, SL, 1987)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199031 (91.18)18.7374
1990's1 (2.94)18.2507
2000's1 (2.94)29.6817
2010's0 (0.00)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Jiang, K1
Feng, J1
Qi, X1
Ran, L1
Xie, L1
GOLDMAN, L1
KITZMILLER, KW1
Wassilew, SW2
Nasemann, T3
de Clercq, E2
Waller, FT1
Tanabe, CT1
Paxton, HD1
Spruance, SL4
McKeough, MB3
Cardinal, JR2
Reichhart, W1
Aguilar, JS1
Roy, D1
Ghazal, P1
Wagner, EK1
Robinson, TW1
Hough, V1
Conte, JE2
Dawber, RP1
Peutherer, JF1
Smith, IW1
Robertson, DH1
Verbov, J2
Nishioka, Y1
Nudel, U1
Ramirez, F1
Silverstein, S1
Woodbridge, P1
Williams, NA1
Hill, TJ2
Whitby, AJ1
Blyth, WA1
Freeman, DJ1
Sacks, SL1
Sheth, NV1
Gauri, KK1
Rohde, B1
Juel-Jensen, BE2
Inglot, AD1
Woytoń, A1
Weitgasser, H1
Turnbull, BC1
MacGregor, I1
Stringer, HC1
MacCallum, FO1
Braun-Falco, O1
Goldschmidt, H1

Trials

2 trials available for dimethyl sulfoxide and Herpes Simplex Virus Infection

ArticleYear
Topical treatment of cutaneous herpes simplex in humans with the non-steroid antiinflammatory drugs: mefenamic acid and indomethacin in dimethylsulfoxide.
    Archivum immunologiae et therapiae experimentalis, 1971, Volume: 19, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Animals; Cells, Cultured; Chick Embryo; Clinical Trials

1971
Herpes simplex virus skin infection in man treated with idoxuridine in dimethyl sulphoxide. Results of double-blind controlled trial.
    British medical journal, 1966, Oct-01, Volume: 2, Issue:5517

    Topics: Clinical Trials as Topic; Dimethyl Sulfoxide; Facial Dermatoses; Herpes Simplex; Humans; Idoxuridine

1966

Other Studies

32 other studies available for dimethyl sulfoxide and Herpes Simplex Virus Infection

ArticleYear
Antiviral Activity of Oridonin Against Herpes Simplex Virus Type 1.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Dimethyl Sulfoxide; Herpes Simplex; Herpesvirus 1,

2022
TOPICAL 5-IODO-2'-DEOXYURIDINE IN DIMETHYLSULFOXIDE (DMSO), A NEW TREATMENT FOR SEVERE HERPES SIMPLEX.
    The Ohio State medical journal, 1965, Volume: 61

    Topics: Deoxyuridine; Dimethyl Sulfoxide; Drug Therapy; Herpes Simplex; Humans; Idoxuridine; Toxicology

1965
[Clinical aspects and importance of human herpex simplex infections. Results of herpes antigen therapy].
    MMW, Munchener medizinische Wochenschrift, 1980, Jan-04, Volume: 122, Issue:1

    Topics: Antigens, Viral; Deoxyuridine; Dimethyl Sulfoxide; Herpes Simplex; Humans; Immunotherapy; Recurrence

1980
Topical treatment of cutaneous herpes simplex virus infection in hairless mice with (E)-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:2

    Topics: Administration, Topical; Animals; Antiviral Agents; Bromodeoxyuridine; Dimethyl Sulfoxide; Herpes Si

1984
Treatment of elevated intracranial pressure with dimethyl sulfoxide.
    Annals of the New York Academy of Sciences, 1983, Volume: 411

    Topics: Adolescent; Adult; Brain Concussion; Cerebral Hemorrhage; Child, Preschool; Dimethyl Sulfoxide; Diur

1983
Dimethyl sulfoxide as a vehicle for topical antiviral chemotherapy.
    Annals of the New York Academy of Sciences, 1983, Volume: 411

    Topics: Acyclovir; Animals; Dimethyl Sulfoxide; Guinea Pigs; Herpes Simplex; Polyethylene Glycols; Skin Abso

1983
Penetration of guinea pig skin by acyclovir in different vehicles and correlation with the efficacy of topical therapy of experimental cutaneous herpes simplex virus infection.
    Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:1

    Topics: Acyclovir; Administration, Topical; Animals; Dimethyl Sulfoxide; Guinea Pigs; Herpes Simplex; Pharma

1984
[Results of a field study using idoxuridine in dimethylsulfoxide in the treatment of herpes zoster and herpes simplex].
    Zeitschrift fur Hautkrankheiten, 1980, Jun-15, Volume: 55, Issue:12

    Topics: Dimethyl Sulfoxide; Drug Combinations; Female; Herpes Simplex; Herpes Zoster; Humans; Idoxuridine; M

1980
Dimethyl sulfoxide blocks herpes simplex virus-1 productive infection in vitro acting at different stages with positive cooperativity. Application of micro-array analysis.
    BMC infectious diseases, 2002, May-24, Volume: 2

    Topics: Animals; Cells, Cultured; Chlorocebus aethiops; Dimethyl Sulfoxide; DNA Replication; Herpes Simplex;

2002
The effect of idoxuridine on herpes simplex virus infection in mouse skin.
    Transactions of the St. John's Hospital Dermatological Society, 1975, Volume: 61, Issue:1-2

    Topics: Animals; Cytarabine; Daunorubicin; Dimethyl Sulfoxide; Herpes Simplex; Idoxuridine; Male; Mice; Simp

1975
[Therapy of veneric diseases].
    Der Internist, 1977, Volume: 18, Issue:5

    Topics: Chlamydia Infections; Dimethyl Sulfoxide; Drug Combinations; Female; Gonorrhea; Herpes Simplex; Huma

1977
Development and therapeutic uses of topical 5% idoxuridine (IDU).
    Scottish medical journal, 1977, Volume: 22, Issue:4

    Topics: Administration, Topical; Chronic Disease; Dimethyl Sulfoxide; Herpes Simplex; Herpes Zoster; History

1977
Necrotising balanitis due to a generalised primary infection with herpes simplex virus type 2.
    The British journal of venereal diseases, 1979, Volume: 55, Issue:1

    Topics: Adult; Balanitis; Dimethyl Sulfoxide; Drug Combinations; Herpes Simplex; Humans; Idoxuridine; Male;

1979
Local idoxuridine treatment of herpes simplex and zoster.
    The Journal of antimicrobial chemotherapy, 1979, Volume: 5, Issue:2

    Topics: Administration, Topical; Dimethyl Sulfoxide; Eczema; Erythema Multiforme; Herpes Simplex; Herpes Zos

1979
[Combined chemotherapy of herpes simplex infections of the skin].
    Zeitschrift fur Hautkrankheiten, 1979, Aug-15, Volume: 54, Issue:16

    Topics: Adult; Deoxyuridine; Dimethyl Sulfoxide; Drug Therapy, Combination; Female; Gels; Genital Diseases,

1979
Differential stability of alpha- and beta-globin mRNAs after infection with herpes simplex virus.
    FEBS letters, 1978, Aug-15, Volume: 92, Issue:2

    Topics: Cells, Cultured; Dimethyl Sulfoxide; Globins; Hemin; Herpes Simplex; Kinetics; Macromolecular Substa

1978
The use of betadine antiseptic paint in the treatment of Herpes simplex and Herpes Zoster.
    The Journal of international medical research, 1977, Volume: 5, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dimethyl Sulfoxide; Female; Herpes Simplex; Herpes

1977
Therapy for venereal diseases.
    Rational drug therapy, 1976, Volume: 10, Issue:9

    Topics: Anti-Bacterial Agents; Chlamydia Infections; Dimethyl Sulfoxide; Female; Gonorrhea; Herpes Simplex;

1976
Effects on murine epidermal Langerhans cells of drugs known to cause recrudescent herpes simplex virus infection in a mouse model.
    The Journal of investigative dermatology, 1991, Volume: 97, Issue:5

    Topics: Adenosine Triphosphatases; Animals; Dimethyl Sulfoxide; Disease Models, Animal; Female; Herpes Simpl

1991
The effect of DNA hypomethylating agents on the reactivation of herpes simplex virus from latently infected mouse ganglia in vitro. Brief report.
    Archives of virology, 1987, Volume: 97, Issue:1-2

    Topics: Animals; Azacitidine; Dimethyl Sulfoxide; DNA, Viral; Ganglia, Sympathetic; Herpes Simplex; In Vitro

1987
Preclinical assessment of topical treatments of herpes simplex virus infection: 5% (E)-5-(2-bromovinyl)-2'-deoxyuridine cream.
    Antiviral research, 1985, Volume: 5, Issue:3

    Topics: Absorption; Acyclovir; Administration, Topical; Animals; Antiviral Agents; Bromodeoxyuridine; Dimeth

1985
Measurement of the stratum corneum drug reservoir to predict the therapeutic efficacy of topical iododeoxyuridine for herpes simplex virus infection.
    The Journal of investigative dermatology, 1987, Volume: 89, Issue:6

    Topics: Administration, Topical; Animals; Dimethyl Sulfoxide; Female; Guinea Pigs; Herpes Simplex; Idoxuridi

1987
[Therapy of herpes simplex and herpes zoster].
    Archiv fur dermatologische Forschung, 1972, Volume: 244

    Topics: Adrenal Cortex Hormones; Dimethyl Sulfoxide; gamma-Globulins; Herpes Simplex; Herpes Zoster; Herpes

1972
[Virostatic effect and clinical use of 1-allyl-3,5-diethyl-6-chlorouracil].
    Klinische Wochenschrift, 1969, Apr-01, Volume: 47, Issue:7

    Topics: Adult; Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Child; Dimethyl Sulfoxide; Ethanol;

1969
Herpes simplex and zoster.
    British medical journal, 1973, Feb-17, Volume: 1, Issue:5850

    Topics: Age Factors; Central Nervous System Diseases; Conjunctivitis; Cytarabine; Dimethyl Sulfoxide; Eczema

1973
Herpes simplex and zoster.
    British medical journal, 1973, Mar-31, Volume: 1, Issue:5856

    Topics: Adrenocorticotropic Hormone; Aged; Dimethyl Sulfoxide; Herpes Simplex; Herpes Zoster; Humans; Pain

1973
[New possibilities of herpes simplex therapy in the dermatological practice].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1973, Volume: 24, Issue:7

    Topics: Adult; Anti-Infective Agents, Local; Antigens, Viral; Dimethyl Sulfoxide; Female; Fever; Herpes Labi

1973
Herpes simplex and zoster.
    British medical journal, 1973, Mar-24, Volume: 1, Issue:5855

    Topics: Cicatrix; Dimethyl Sulfoxide; Herpes Simplex; Herpes Zoster; Humans; Idoxuridine; Skin Diseases

1973
Treatment of herpes simplex.
    The British journal of dermatology, 1971, Volume: 85, Issue:6

    Topics: Dimethyl Sulfoxide; Female; Herpes Simplex; Humans; Idoxuridine; Male

1971
The enhancing effect of dimethylsulfoxide vehicle upon the anti-viral actions of 5-iododeoxyuridine.
    The New Zealand medical journal, 1969, Volume: 70, Issue:450

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dimethyl Sulfoxide; Female; Herpes Simplex; Herpes

1969
[Virustatic substances in local treatment of herpetic dermatoses].
    Therapie der Gegenwart, 1970, Volume: 109, Issue:2

    Topics: Adult; Antiviral Agents; Child; Deoxyuridine; Dermatologic Agents; Dimethyl Sulfoxide; Female; Herpe

1970
How I treat herpes simplex.
    Postgraduate medicine, 1968, Volume: 44, Issue:6

    Topics: Anti-Bacterial Agents; Dimethyl Sulfoxide; Herpes Simplex; Humans; Idoxuridine

1968