dimethyl sulfoxide has been researched along with Glomus Jugulare Tumor in 4 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Glomus Jugulare Tumor: A paraganglioma involving the glomus jugulare, a microscopic collection of chemoreceptor tissue in the adventitia of the bulb of the jugular vein. It may cause paralysis of the vocal cords, attacks of dizziness, blackouts, and nystagmus. It is not resectable but radiation therapy is effective. It regresses slowly, but permanent control is regularly achieved. (From Dorland, 27th ed; Stedman, 25th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1603-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The resection of glomus jugulare tumors can be challenging because of their inherent vascularity." | 1.40 | Incidence of cranial nerve palsy after preoperative embolization of glomus jugulare tumors using Onyx. ( Angeli, SI; Aziz-Sultan, MA; Elhammady, MS; Gaynor, BG; Jethanamest, D, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gaynor, BG | 2 |
| Elhammady, MS | 2 |
| Jethanamest, D | 1 |
| Angeli, SI | 1 |
| Aziz-Sultan, MA | 1 |
| Lanzino, G | 1 |
| Burrows, AM | 1 |
| Cloft, HJ | 1 |
| Spelle, L | 1 |
| Ruijters, D | 1 |
| Babic, D | 1 |
| Homan, R | 1 |
| Mielekamp, P | 1 |
| Guillermic, J | 1 |
| Moret, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Randomized Trial Comparing Navigation With Xperguide vs. Conventional Methods During Percutaneous Image Guided Procedures[NCT01287013] | 87 participants (Actual) | Interventional | 2011-01-31 | Terminated (stopped due to Investigator left NIH) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Comparing the accuracy of the path the biopsy needle took to get to the site (NCT01287013)
Timeframe: 1 hour
| Intervention | mm (Mean) |
|---|---|
| Cone Beam CT | 8.8 |
| Convetional CT | 28.3 |
To compare the number of times the needle must be repositioned during the guidance of the needle to the biopsy. (NCT01287013)
Timeframe: 1 hour
| Intervention | number of repositioning maneuvers (Mean) |
|---|---|
| Cone Beam CT | 0.3 |
| Conventional CT | 1.9 |
To compare the accuracy of the biopsy needle between the software guidance and conventional CT. The accuracy of the needle position was calculated in millimeters by using the difference between the x,y,z coordinates of the tip of the actual needle before specimen collection. Actual and planned needle paths were compared using coordinates and measured in millimeters. (NCT01287013)
Timeframe: 1 hour
| Intervention | mm (Mean) |
|---|---|
| Cone Beam CT | 4.9 |
| Conventional CT | 12.2 |
Comparing radiation doses to determine if there is a change in the dose between the two interventions (NCT01287013)
Timeframe: 1 hour
| Intervention | mGy (Mean) |
|---|---|
| Cone Beam CT | 53.3 |
| Conventional CT | 75.4 |
Definitive pathologic diagnosis was defined as an adequate specimen as judged by the pathologist and a diagnosis confirmed by surgery or clinical follow-up. (NCT01287013)
Timeframe: 1 hour
| Intervention | percent of accuracy (Number) |
|---|---|
| Cone Beam CT | 93.9 |
| Conventional CT | 90.9 |
4 other studies available for dimethyl sulfoxide and Glomus Jugulare Tumor
| Article | Year |
|---|---|
Incidence of cranial nerve palsy after preoperative embolization of glomus jugulare tumors using Onyx.
Topics: Adult; Aged; Brain Neoplasms; Cerebral Angiography; Cerebral Revascularization; Cranial Nerve Diseas | 2014 |
Onyx embolization.
Topics: Cranial Nerve Diseases; Dimethyl Sulfoxide; Embolization, Therapeutic; Female; Glomus Jugulare Tumor | 2014 |
Response.
Topics: Cranial Nerve Diseases; Dimethyl Sulfoxide; Embolization, Therapeutic; Female; Glomus Jugulare Tumor | 2014 |
First clinical experience in applying XperGuide in embolization of jugular paragangliomas by direct intratumoral puncture.
Topics: Contrast Media; Dimethyl Sulfoxide; Female; Fluoroscopy; Glomus Jugulare Tumor; Humans; Imaging, Thr | 2009 |