dimethyl sulfoxide has been researched along with Glaucoma in 4 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present work, a cost-effective, stable and sustained release ophthalmic solution formulation of brinzolamide (BRZ) was developed for the treatment of glaucoma." | 3.96 | Brinzolamide Dimethyl Sulfoxide In Situ Gelling Ophthalmic Solution: Formulation Optimisation and In Vitro and In Vivo Evaluation. ( Bhalerao, H; Chandran, S; Koteshwara, KB, 2020) |
| " Therefore, we tested metal chelation by means of ethylenediaminetetraacetic acid (EDTA) combined with the permeability enhancer methylsulfonylmethane (MSM) applied topically on the eye to determine if this noninvasive treatment is neuroprotective in rat optic nerve and retinal ganglion cells exposed to oxidative stress induced by elevated IOP." | 1.40 | Metal chelator combined with permeability enhancer ameliorates oxidative stress-associated neurodegeneration in rat eyes with elevated intraocular pressure. ( Ansari, NH; Campbell, GA; Hogan, D; Liu, P; Shoeb, M; Syed, MF; Tang, L; Wang, CZ; Zhang, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Swain, R | 1 |
| Moharana, A | 1 |
| Habibullah, S | 1 |
| Nandi, S | 1 |
| Bose, A | 1 |
| Mohapatra, S | 1 |
| Mallick, S | 1 |
| Bhalerao, H | 1 |
| Koteshwara, KB | 1 |
| Chandran, S | 1 |
| Liu, P | 1 |
| Zhang, M | 1 |
| Shoeb, M | 1 |
| Hogan, D | 1 |
| Tang, L | 1 |
| Syed, MF | 1 |
| Wang, CZ | 1 |
| Campbell, GA | 1 |
| Ansari, NH | 1 |
| Gordon, DM | 1 |
4 other studies available for dimethyl sulfoxide and Glaucoma
| Article | Year |
|---|---|
Ocular delivery of felodipine for the management of intraocular pressure and inflammation: Effect of film plasticizer and in vitro in vivo evaluation.
Topics: Animals; Dimethyl Sulfoxide; Felodipine; Glaucoma; Intraocular Pressure; Plasticizers; Rabbits; Trab | 2023 |
Brinzolamide Dimethyl Sulfoxide In Situ Gelling Ophthalmic Solution: Formulation Optimisation and In Vitro and In Vivo Evaluation.
Topics: Animals; Castor Oil; Dimethyl Sulfoxide; Drug Compounding; Drug Liberation; Excipients; Gels; Glauco | 2020 |
Metal chelator combined with permeability enhancer ameliorates oxidative stress-associated neurodegeneration in rat eyes with elevated intraocular pressure.
Topics: Animals; Chelating Agents; Dimethyl Sulfoxide; Edetic Acid; Glaucoma; Humans; Intracranial Hypertens | 2014 |
Dimethyl sulfoxide in ophthalmology, with especial reference to possible toxic effects.
Topics: Adolescent; Adult; Aged; Cataract; Conjunctivitis; Dimethyl Sulfoxide; Eye Diseases; Female; Glaucom | 1967 |