dimethyl sulfoxide has been researched along with Germinoblastoma in 28 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of Na[trans-RuCl4(DMSO)Im] (NAMI), Na[trans-RuCl4(TMSO) Ind] (TIND) and Na[trans-RuCl4(TMSO)Iq] TEQU) were tested in vitro on TLX5 lymphoma cells in comparison to cisplatin by means of the sulforhodamine-B test SRB) for protein content determination, by acridine orange and propidium iodide staining and by means of the bromodeoxyuridine test, for cell cycle modifications." | 7.70 | Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry. ( Bergamo, A; Capozzi, I; Clerici, K; Cocchietto, M; Salerno, G; Sava, G, 1998) |
| "The effects of dimethyl sulfoxide (DMSO) on H-2 expression and susceptibility to NK- and cytotoxic T-lymphocyte (CTL)-mediated lysis in the murine T-cell lymphoma YAC-1 and its beta-2-microglobulin (beta 2m)-deficient variant were studied." | 7.67 | Effects of dimethyl sulfoxide treatment on H-2 expression and susceptibility to NK- or cytotoxic T-lymphocyte-mediated lysis of the YAC-1 lymphoma and its beta 2-microglobulin-deficient variant. ( Höglund, P; Kärre, K; Klein, G; Ljunggren, HG; Ohlén, C; Petersson, MG; Yamasaki, T, 1988) |
| " Forty marrows, which derived from patients suffering with leukemia and lymphoma, were fractionated with Ficoll on a COBE machine and in vitro purged with Mafosfamide at a dose of 50 micrograms/ml/1 x 10e7 MN cells." | 5.07 | Density gradient separation of hematopoietic stem cells in autologous bone marrow transplantation. ( Accorsi, P; Angelini, A; Angrilli, F; Berardi, A; D'Antonio, D; Di Bartolomeo, G; Di Bartolomeo, P; Dragani, A; Iacone, A; Quaglietta, AM, 1991) |
| "The effects of Na[trans-RuCl4(DMSO)Im] (NAMI), Na[trans-RuCl4(TMSO) Ind] (TIND) and Na[trans-RuCl4(TMSO)Iq] TEQU) were tested in vitro on TLX5 lymphoma cells in comparison to cisplatin by means of the sulforhodamine-B test SRB) for protein content determination, by acridine orange and propidium iodide staining and by means of the bromodeoxyuridine test, for cell cycle modifications." | 3.70 | Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry. ( Bergamo, A; Capozzi, I; Clerici, K; Cocchietto, M; Salerno, G; Sava, G, 1998) |
| " Fluorescence microscopy and polyacrylamide gel analysis showed that the fluorescein-labeled PS-TFO accumulated in nuclei of CEM leukemia cells and remained intact for at least 72 h." | 3.70 | Antigene and antiproliferative effects of a c-myc-targeting phosphorothioate triple helix-forming oligonucleotide in human leukemia cells. ( Carbone, GM; Catapano, CV; McGuffie, EM; Pacheco, D, 2000) |
| "The effects of dimethyl sulfoxide (DMSO) on H-2 expression and susceptibility to NK- and cytotoxic T-lymphocyte (CTL)-mediated lysis in the murine T-cell lymphoma YAC-1 and its beta-2-microglobulin (beta 2m)-deficient variant were studied." | 3.67 | Effects of dimethyl sulfoxide treatment on H-2 expression and susceptibility to NK- or cytotoxic T-lymphocyte-mediated lysis of the YAC-1 lymphoma and its beta 2-microglobulin-deficient variant. ( Höglund, P; Kärre, K; Klein, G; Ljunggren, HG; Ohlén, C; Petersson, MG; Yamasaki, T, 1988) |
| "In the present investigation we have determined the effects of the differentiation-inducing chemicals dimethyl sulfoxide (DMSO) and sodium butyrate on the growth and tumorigenicity of a highly malignant/metastatic cell line (RAW117-H10) and its less tumorigenic parental lymphoma cell line (RAW117-P)." | 3.67 | Effects of differentiation inducing chemicals on in vivo malignancy and NK susceptibility of metastatic lymphoma cells. ( Brunson, KW; Joshi, SS; Mathews, NB; Sharp, JG; Sinangil, F; Volsky, DJ, 1988) |
| "In somatic cell hybrids formed by the fusion of mouse erythroleukemic cells with cultured mouse lymphoma cells, retention of the X chromosome donated by the lymphoma parent is correlated with inhibition of hemoglobin accumulation in response to dimethyl sulfoxide." | 3.66 | X-linked control of globin mRNA and hemoglobin production in erythroleukemia-lymphoma cell hybrids. ( Benoff, S; Bruce, SA; Skoultchi, AI, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (67.86) | 18.7374 |
| 1990's | 4 (14.29) | 18.2507 |
| 2000's | 3 (10.71) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reich-Slotky, R | 1 |
| Makhani, SS | 1 |
| Vasovic, LV | 1 |
| Pearse, RN | 1 |
| Rossi, A | 1 |
| Philips, A | 1 |
| Cushing, MM | 1 |
| Singh, AD | 1 |
| van Besien, K | 1 |
| Koiri, RK | 1 |
| Trigun, SK | 1 |
| Niller, HH | 1 |
| Salamon, D | 1 |
| Ilg, K | 1 |
| Koroknai, A | 1 |
| Banati, F | 1 |
| Bauml, G | 1 |
| Rucker, O | 1 |
| Schwarzmann, F | 1 |
| Wolf, H | 1 |
| Minarovits, J | 1 |
| Akkök, CA | 1 |
| Liseth, K | 1 |
| Nesthus, I | 1 |
| Løkeland, T | 1 |
| Tefre, K | 1 |
| Bruserud, O | 1 |
| Abrahamsen, JF | 1 |
| Adolf, GR | 1 |
| Haas, OA | 1 |
| Fischer, P | 1 |
| Swetly, P | 1 |
| Santoli, D | 1 |
| Francis, MK | 1 |
| Matera, L | 1 |
| Ferrero, D | 1 |
| Beaujean, F | 1 |
| Hartmann, O | 1 |
| Le Forestier, C | 1 |
| Bayet, S | 1 |
| Duédari, N | 1 |
| Parmentier, C | 1 |
| Anderson, NL | 1 |
| Hofmann, JP | 1 |
| Gemmell, A | 1 |
| Taylor, J | 1 |
| Chow, DA | 1 |
| Benoff, S | 1 |
| Bruce, SA | 1 |
| Skoultchi, AI | 1 |
| Klein, F | 1 |
| Ricketts, RT | 1 |
| Galmés, A | 1 |
| Besalduch, J | 1 |
| Bargay, J | 1 |
| Matamoros, N | 1 |
| Morey, M | 1 |
| Novo, A | 1 |
| Sampol, A | 1 |
| Capozzi, I | 1 |
| Clerici, K | 1 |
| Cocchietto, M | 1 |
| Salerno, G | 1 |
| Bergamo, A | 1 |
| Sava, G | 1 |
| McGuffie, EM | 1 |
| Pacheco, D | 1 |
| Carbone, GM | 1 |
| Catapano, CV | 1 |
| Weimann, BJ | 1 |
| Hu, HY | 1 |
| Gardner, J | 1 |
| Aisen, P | 1 |
| Ortaldo, JR | 1 |
| Oldham, RK | 1 |
| Holden, HT | 1 |
| Herberman, RB | 1 |
| Iacone, A | 1 |
| Quaglietta, AM | 1 |
| D'Antonio, D | 1 |
| Accorsi, P | 1 |
| Dragani, A | 1 |
| Angrilli, F | 1 |
| Berardi, A | 1 |
| Angelini, A | 1 |
| Di Bartolomeo, P | 1 |
| Di Bartolomeo, G | 1 |
| Bhide, SV | 1 |
| Ammigan, N | 1 |
| Nair, UJ | 1 |
| Lalitha, VS | 1 |
| Rosoff, PM | 1 |
| Cantley, LC | 1 |
| Yamasaki, T | 1 |
| Klein, G | 1 |
| Ljunggren, HG | 1 |
| Höglund, P | 1 |
| Ohlén, C | 1 |
| Petersson, MG | 1 |
| Kärre, K | 1 |
| Joshi, SS | 1 |
| Sinangil, F | 1 |
| Sharp, JG | 1 |
| Mathews, NB | 1 |
| Volsky, DJ | 1 |
| Brunson, KW | 1 |
| Moennig, V | 2 |
| Frank, H | 1 |
| Hunsmann, G | 2 |
| Ohms, P | 1 |
| Schwarz, H | 2 |
| Schäfer, W | 2 |
| Seibert, FB | 1 |
| Farrelly, FK | 1 |
| Shepherd, CC | 1 |
| Hollander, A | 1 |
| Strandström, H | 1 |
| Veijalainen, P | 1 |
| Schrek, R | 2 |
| Rappaport, H | 1 |
| Rubnitz, ME | 1 |
| Kwaan, HC | 1 |
| Elrod, LM | 1 |
| Batra, KV | 1 |
2 reviews available for dimethyl sulfoxide and Germinoblastoma
| Article | Year |
|---|---|
Ion fluxes and differentiation in transformed cell lines.
Topics: Amiloride; Animals; Calcimycin; Calcium; Carrier Proteins; Cell Differentiation; Cell Line; Cell Tra | 1985 |
[News concerning dermatology in America. II].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Antifungal Agents; Carcinoma, Basal Cell; Chi | 1969 |
2 trials available for dimethyl sulfoxide and Germinoblastoma
| Article | Year |
|---|---|
A simplified method for cryopreservation of hematopoietic stem cells with -80 degrees C mechanical freezer with dimethyl sulfoxide as the sole cryoprotectant.
Topics: Adult; Blood Preservation; Breast Neoplasms; Cryopreservation; Dimethyl Sulfoxide; Female; Freezing; | 1995 |
Density gradient separation of hematopoietic stem cells in autologous bone marrow transplantation.
Topics: Bone Marrow Transplantation; Cell Separation; Centrifugation, Density Gradient; Cryoprotective Agent | 1991 |
24 other studies available for dimethyl sulfoxide and Germinoblastoma
| Article | Year |
|---|---|
Comparison of time to engraftment between autologous patients receiving washed versus non-washed cryopreserved peripheral blood stem cell products.
Topics: Aged; Blood Platelets; Cell Survival; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; F | 2018 |
Dimethyl sulfoxide activates tumor necrosis factorα-p53 mediated apoptosis and down regulates D-fructose-6-phosphate-2-kinase and lactate dehydrogenase-5 in Dalton's lymphoma in vivo.
Topics: Animals; Apoptosis; Cells, Cultured; Dimethyl Sulfoxide; Down-Regulation; Isoenzymes; L-Lactate Dehy | 2011 |
The in vivo binding site for oncoprotein c-Myc in the promoter for Epstein-Barr virus (EBV) encoding RNA (EBER) 1 suggests a specific role for EBV in lymphomagenesis.
Topics: Binding Sites; Cell Line, Transformed; Chromatin; Dimethyl Sulfoxide; Genes, myc; Herpesvirus 4, Hum | 2003 |
Autologous peripheral blood progenitor cells cryopreserved with 5 and 10 percent dimethyl sulfoxide alone give comparable hematopoietic reconstitution after transplantation.
Topics: Adolescent; Adult; Antigens, CD34; Blood Preservation; Blood Transfusion; Cryopreservation; Cryoprot | 2008 |
Spontaneous production of alpha- and beta-interferon in human lymphoblastoid and lymphoma cell lines.
Topics: Bromodeoxyuridine; Cell Line; Dexamethasone; Dimethyl Sulfoxide; Hematopoiesis; Humans; Interferons; | 1982 |
Induction of proliferation and NK activity in human lymphocytes by mature myelomonocytic cells: evidence for an HLA-DR-independent MLR stimulatory ability of terminally differentiated nonlymphoid leukemic cell lines and of normal peripheral blood granuloc
Topics: Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Granulocytes; Histiocytoma, Beni | 1983 |
Successful infusion of 40 cryopreserved autologous bone-marrows. In vitro studies of the freezing procedure.
Topics: Adolescent; Adult; Antineoplastic Agents; Bone Marrow; Bone Marrow Transplantation; Child; Child, Pr | 1984 |
Global approaches to quantitative analysis of gene-expression patterns observed by use of two-dimensional gel electrophoresis.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Electrophoresis; Electrophoresis, Polyacrylamid | 1984 |
Variant generation and selection: an in vitro model of tumor progression.
Topics: Animals; Antibodies, Neoplasm; Cell Line; Clone Cells; Culture Media; Cytotoxicity, Immunologic; Dim | 1984 |
X-linked control of globin mRNA and hemoglobin production in erythroleukemia-lymphoma cell hybrids.
Topics: Aminolevulinic Acid; Animals; Dimethyl Sulfoxide; Female; Genetic Linkage; Globins; Hemin; Hemoglobi | 1980 |
Uniform production and bulk storage of P388 murine lymphoma cells for antitumor assay.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Cytological Techniques; Dar | 1980 |
Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle; Cell Survival; Cisplatin; Dimethyl Su | 1998 |
Antigene and antiproliferative effects of a c-myc-targeting phosphorothioate triple helix-forming oligonucleotide in human leukemia cells.
Topics: Antigens; Apoptosis; Blotting, Western; Cell Division; Cell Nucleus; Contrast Media; Dimethyl Sulfox | 2000 |
Induction of immunoglobulin synthesis in Abelson murine leukemia virus-transformed mouse lymphoma cells in culture.
Topics: B-Lymphocytes; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; | 1977 |
Inducibility of transferrin receptors on friend erythroleukemic cells.
Topics: Cell Line; Dimethyl Sulfoxide; Erythrocytes; Erythropoiesis; Fibroblasts; Friend murine leukemia vir | 1977 |
Immune response to Gross virus-induced lymphoma: cryopreservation of functional activity of rat lymphocytes and tumor cells.
Topics: AKR murine leukemia virus; Animals; Cytotoxicity Tests, Immunologic; Dimethyl Sulfoxide; Freezing; L | 1976 |
Carcinogenicity studies of tobacco extract in vitamin A-deficient Sprague-Dawley rats.
Topics: Adenoma; Animals; Body Weight; Carcinogenicity Tests; Dimethyl Sulfoxide; Liver; Lung; Lung Neoplasm | 1991 |
Effects of dimethyl sulfoxide treatment on H-2 expression and susceptibility to NK- or cytotoxic T-lymphocyte-mediated lysis of the YAC-1 lymphoma and its beta 2-microglobulin-deficient variant.
Topics: Animals; beta 2-Microglobulin; Cell Survival; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; H-2 Ant | 1988 |
Effects of differentiation inducing chemicals on in vivo malignancy and NK susceptibility of metastatic lymphoma cells.
Topics: Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cell Line; Cytotoxicity, Immu | 1988 |
C-type particles produced by a permanent cell line from a leukemic pig. II. Physical, chemical, and serological characterization of the particles.
Topics: Animals; Antigens, Viral; Bromodeoxyuridine; Cell Line; Centrifugation, Density Gradient; Chemical P | 1974 |
DMSO and other combatants against bacteria isolated from leukemia and cancer patients.
Topics: Antitubercular Agents; Bacteria; Bacteriological Techniques; Blood Cells; Culture Media; Dimethyl Su | 1967 |
C-type particles produced by a permanent cell line from a leukemic pig. I. Origin and properties of the host cells and some evidence for the occurrence of C-type-like particles.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Dimethyl Sul | 1974 |
Cytology and reactions of viable cells from malignant lymphoma.
Topics: Adult; Aged; Asparaginase; Cell Differentiation; Cell Transformation, Neoplastic; Dimethyl Sulfoxide | 1969 |
Cytocidal effect of dimethyl sulfoxide on normal and leukemic lymphocytes.
Topics: Animals; Antineoplastic Agents; Cell Division; Dimethyl Sulfoxide; Hot Temperature; Humans; In Vitro | 1967 |