Page last updated: 2024-10-18

dimethyl sulfoxide and Germinoblastoma

dimethyl sulfoxide has been researched along with Germinoblastoma in 28 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Research Excerpts

ExcerptRelevanceReference
"The effects of Na[trans-RuCl4(DMSO)Im] (NAMI), Na[trans-RuCl4(TMSO) Ind] (TIND) and Na[trans-RuCl4(TMSO)Iq] TEQU) were tested in vitro on TLX5 lymphoma cells in comparison to cisplatin by means of the sulforhodamine-B test SRB) for protein content determination, by acridine orange and propidium iodide staining and by means of the bromodeoxyuridine test, for cell cycle modifications."7.70Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry. ( Bergamo, A; Capozzi, I; Clerici, K; Cocchietto, M; Salerno, G; Sava, G, 1998)
"The effects of dimethyl sulfoxide (DMSO) on H-2 expression and susceptibility to NK- and cytotoxic T-lymphocyte (CTL)-mediated lysis in the murine T-cell lymphoma YAC-1 and its beta-2-microglobulin (beta 2m)-deficient variant were studied."7.67Effects of dimethyl sulfoxide treatment on H-2 expression and susceptibility to NK- or cytotoxic T-lymphocyte-mediated lysis of the YAC-1 lymphoma and its beta 2-microglobulin-deficient variant. ( Höglund, P; Kärre, K; Klein, G; Ljunggren, HG; Ohlén, C; Petersson, MG; Yamasaki, T, 1988)
" Forty marrows, which derived from patients suffering with leukemia and lymphoma, were fractionated with Ficoll on a COBE machine and in vitro purged with Mafosfamide at a dose of 50 micrograms/ml/1 x 10e7 MN cells."5.07Density gradient separation of hematopoietic stem cells in autologous bone marrow transplantation. ( Accorsi, P; Angelini, A; Angrilli, F; Berardi, A; D'Antonio, D; Di Bartolomeo, G; Di Bartolomeo, P; Dragani, A; Iacone, A; Quaglietta, AM, 1991)
"The effects of Na[trans-RuCl4(DMSO)Im] (NAMI), Na[trans-RuCl4(TMSO) Ind] (TIND) and Na[trans-RuCl4(TMSO)Iq] TEQU) were tested in vitro on TLX5 lymphoma cells in comparison to cisplatin by means of the sulforhodamine-B test SRB) for protein content determination, by acridine orange and propidium iodide staining and by means of the bromodeoxyuridine test, for cell cycle modifications."3.70Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry. ( Bergamo, A; Capozzi, I; Clerici, K; Cocchietto, M; Salerno, G; Sava, G, 1998)
" Fluorescence microscopy and polyacrylamide gel analysis showed that the fluorescein-labeled PS-TFO accumulated in nuclei of CEM leukemia cells and remained intact for at least 72 h."3.70Antigene and antiproliferative effects of a c-myc-targeting phosphorothioate triple helix-forming oligonucleotide in human leukemia cells. ( Carbone, GM; Catapano, CV; McGuffie, EM; Pacheco, D, 2000)
"The effects of dimethyl sulfoxide (DMSO) on H-2 expression and susceptibility to NK- and cytotoxic T-lymphocyte (CTL)-mediated lysis in the murine T-cell lymphoma YAC-1 and its beta-2-microglobulin (beta 2m)-deficient variant were studied."3.67Effects of dimethyl sulfoxide treatment on H-2 expression and susceptibility to NK- or cytotoxic T-lymphocyte-mediated lysis of the YAC-1 lymphoma and its beta 2-microglobulin-deficient variant. ( Höglund, P; Kärre, K; Klein, G; Ljunggren, HG; Ohlén, C; Petersson, MG; Yamasaki, T, 1988)
"In the present investigation we have determined the effects of the differentiation-inducing chemicals dimethyl sulfoxide (DMSO) and sodium butyrate on the growth and tumorigenicity of a highly malignant/metastatic cell line (RAW117-H10) and its less tumorigenic parental lymphoma cell line (RAW117-P)."3.67Effects of differentiation inducing chemicals on in vivo malignancy and NK susceptibility of metastatic lymphoma cells. ( Brunson, KW; Joshi, SS; Mathews, NB; Sharp, JG; Sinangil, F; Volsky, DJ, 1988)
"In somatic cell hybrids formed by the fusion of mouse erythroleukemic cells with cultured mouse lymphoma cells, retention of the X chromosome donated by the lymphoma parent is correlated with inhibition of hemoglobin accumulation in response to dimethyl sulfoxide."3.66X-linked control of globin mRNA and hemoglobin production in erythroleukemia-lymphoma cell hybrids. ( Benoff, S; Bruce, SA; Skoultchi, AI, 1980)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199019 (67.86)18.7374
1990's4 (14.29)18.2507
2000's3 (10.71)29.6817
2010's2 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reich-Slotky, R1
Makhani, SS1
Vasovic, LV1
Pearse, RN1
Rossi, A1
Philips, A1
Cushing, MM1
Singh, AD1
van Besien, K1
Koiri, RK1
Trigun, SK1
Niller, HH1
Salamon, D1
Ilg, K1
Koroknai, A1
Banati, F1
Bauml, G1
Rucker, O1
Schwarzmann, F1
Wolf, H1
Minarovits, J1
Akkök, CA1
Liseth, K1
Nesthus, I1
Løkeland, T1
Tefre, K1
Bruserud, O1
Abrahamsen, JF1
Adolf, GR1
Haas, OA1
Fischer, P1
Swetly, P1
Santoli, D1
Francis, MK1
Matera, L1
Ferrero, D1
Beaujean, F1
Hartmann, O1
Le Forestier, C1
Bayet, S1
Duédari, N1
Parmentier, C1
Anderson, NL1
Hofmann, JP1
Gemmell, A1
Taylor, J1
Chow, DA1
Benoff, S1
Bruce, SA1
Skoultchi, AI1
Klein, F1
Ricketts, RT1
Galmés, A1
Besalduch, J1
Bargay, J1
Matamoros, N1
Morey, M1
Novo, A1
Sampol, A1
Capozzi, I1
Clerici, K1
Cocchietto, M1
Salerno, G1
Bergamo, A1
Sava, G1
McGuffie, EM1
Pacheco, D1
Carbone, GM1
Catapano, CV1
Weimann, BJ1
Hu, HY1
Gardner, J1
Aisen, P1
Ortaldo, JR1
Oldham, RK1
Holden, HT1
Herberman, RB1
Iacone, A1
Quaglietta, AM1
D'Antonio, D1
Accorsi, P1
Dragani, A1
Angrilli, F1
Berardi, A1
Angelini, A1
Di Bartolomeo, P1
Di Bartolomeo, G1
Bhide, SV1
Ammigan, N1
Nair, UJ1
Lalitha, VS1
Rosoff, PM1
Cantley, LC1
Yamasaki, T1
Klein, G1
Ljunggren, HG1
Höglund, P1
Ohlén, C1
Petersson, MG1
Kärre, K1
Joshi, SS1
Sinangil, F1
Sharp, JG1
Mathews, NB1
Volsky, DJ1
Brunson, KW1
Moennig, V2
Frank, H1
Hunsmann, G2
Ohms, P1
Schwarz, H2
Schäfer, W2
Seibert, FB1
Farrelly, FK1
Shepherd, CC1
Hollander, A1
Strandström, H1
Veijalainen, P1
Schrek, R2
Rappaport, H1
Rubnitz, ME1
Kwaan, HC1
Elrod, LM1
Batra, KV1

Reviews

2 reviews available for dimethyl sulfoxide and Germinoblastoma

ArticleYear
Ion fluxes and differentiation in transformed cell lines.
    Society of General Physiologists series, 1985, Volume: 39

    Topics: Amiloride; Animals; Calcimycin; Calcium; Carrier Proteins; Cell Differentiation; Cell Line; Cell Tra

1985
[News concerning dermatology in America. II].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1969, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Antifungal Agents; Carcinoma, Basal Cell; Chi

1969

Trials

2 trials available for dimethyl sulfoxide and Germinoblastoma

ArticleYear
A simplified method for cryopreservation of hematopoietic stem cells with -80 degrees C mechanical freezer with dimethyl sulfoxide as the sole cryoprotectant.
    Leukemia & lymphoma, 1995, Volume: 17, Issue:1-2

    Topics: Adult; Blood Preservation; Breast Neoplasms; Cryopreservation; Dimethyl Sulfoxide; Female; Freezing;

1995
Density gradient separation of hematopoietic stem cells in autologous bone marrow transplantation.
    Haematologica, 1991, Volume: 76 Suppl 1

    Topics: Bone Marrow Transplantation; Cell Separation; Centrifugation, Density Gradient; Cryoprotective Agent

1991

Other Studies

24 other studies available for dimethyl sulfoxide and Germinoblastoma

ArticleYear
Comparison of time to engraftment between autologous patients receiving washed versus non-washed cryopreserved peripheral blood stem cell products.
    Leukemia & lymphoma, 2018, Volume: 59, Issue:12

    Topics: Aged; Blood Platelets; Cell Survival; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; F

2018
Dimethyl sulfoxide activates tumor necrosis factorα-p53 mediated apoptosis and down regulates D-fructose-6-phosphate-2-kinase and lactate dehydrogenase-5 in Dalton's lymphoma in vivo.
    Leukemia research, 2011, Volume: 35, Issue:7

    Topics: Animals; Apoptosis; Cells, Cultured; Dimethyl Sulfoxide; Down-Regulation; Isoenzymes; L-Lactate Dehy

2011
The in vivo binding site for oncoprotein c-Myc in the promoter for Epstein-Barr virus (EBV) encoding RNA (EBER) 1 suggests a specific role for EBV in lymphomagenesis.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:1

    Topics: Binding Sites; Cell Line, Transformed; Chromatin; Dimethyl Sulfoxide; Genes, myc; Herpesvirus 4, Hum

2003
Autologous peripheral blood progenitor cells cryopreserved with 5 and 10 percent dimethyl sulfoxide alone give comparable hematopoietic reconstitution after transplantation.
    Transfusion, 2008, Volume: 48, Issue:5

    Topics: Adolescent; Adult; Antigens, CD34; Blood Preservation; Blood Transfusion; Cryopreservation; Cryoprot

2008
Spontaneous production of alpha- and beta-interferon in human lymphoblastoid and lymphoma cell lines.
    Archives of virology, 1982, Volume: 72, Issue:3

    Topics: Bromodeoxyuridine; Cell Line; Dexamethasone; Dimethyl Sulfoxide; Hematopoiesis; Humans; Interferons;

1982
Induction of proliferation and NK activity in human lymphocytes by mature myelomonocytic cells: evidence for an HLA-DR-independent MLR stimulatory ability of terminally differentiated nonlymphoid leukemic cell lines and of normal peripheral blood granuloc
    Journal of immunology (Baltimore, Md. : 1950), 1983, Volume: 131, Issue:2

    Topics: Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Granulocytes; Histiocytoma, Beni

1983
Successful infusion of 40 cryopreserved autologous bone-marrows. In vitro studies of the freezing procedure.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1984, Volume: 38, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Agents; Bone Marrow; Bone Marrow Transplantation; Child; Child, Pr

1984
Global approaches to quantitative analysis of gene-expression patterns observed by use of two-dimensional gel electrophoresis.
    Clinical chemistry, 1984, Volume: 30, Issue:12 Pt 1

    Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Electrophoresis; Electrophoresis, Polyacrylamid

1984
Variant generation and selection: an in vitro model of tumor progression.
    International journal of cancer, 1984, Apr-15, Volume: 33, Issue:4

    Topics: Animals; Antibodies, Neoplasm; Cell Line; Clone Cells; Culture Media; Cytotoxicity, Immunologic; Dim

1984
X-linked control of globin mRNA and hemoglobin production in erythroleukemia-lymphoma cell hybrids.
    Somatic cell genetics, 1980, Volume: 6, Issue:1

    Topics: Aminolevulinic Acid; Animals; Dimethyl Sulfoxide; Female; Genetic Linkage; Globins; Hemin; Hemoglobi

1980
Uniform production and bulk storage of P388 murine lymphoma cells for antitumor assay.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1980, Volume: 163, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Cytological Techniques; Dar

1980
Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry.
    Chemico-biological interactions, 1998, May-01, Volume: 113, Issue:1

    Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle; Cell Survival; Cisplatin; Dimethyl Su

1998
Antigene and antiproliferative effects of a c-myc-targeting phosphorothioate triple helix-forming oligonucleotide in human leukemia cells.
    Cancer research, 2000, Jul-15, Volume: 60, Issue:14

    Topics: Antigens; Apoptosis; Blotting, Western; Cell Division; Cell Nucleus; Contrast Media; Dimethyl Sulfox

2000
Induction of immunoglobulin synthesis in Abelson murine leukemia virus-transformed mouse lymphoma cells in culture.
    Cold Spring Harbor symposia on quantitative biology, 1977, Volume: 41 Pt 1

    Topics: B-Lymphocytes; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide;

1977
Inducibility of transferrin receptors on friend erythroleukemic cells.
    Science (New York, N.Y.), 1977, Aug-05, Volume: 197, Issue:4303

    Topics: Cell Line; Dimethyl Sulfoxide; Erythrocytes; Erythropoiesis; Fibroblasts; Friend murine leukemia vir

1977
Immune response to Gross virus-induced lymphoma: cryopreservation of functional activity of rat lymphocytes and tumor cells.
    Cellular immunology, 1976, Volume: 25, Issue:1

    Topics: AKR murine leukemia virus; Animals; Cytotoxicity Tests, Immunologic; Dimethyl Sulfoxide; Freezing; L

1976
Carcinogenicity studies of tobacco extract in vitamin A-deficient Sprague-Dawley rats.
    Cancer research, 1991, Jun-01, Volume: 51, Issue:11

    Topics: Adenoma; Animals; Body Weight; Carcinogenicity Tests; Dimethyl Sulfoxide; Liver; Lung; Lung Neoplasm

1991
Effects of dimethyl sulfoxide treatment on H-2 expression and susceptibility to NK- or cytotoxic T-lymphocyte-mediated lysis of the YAC-1 lymphoma and its beta 2-microglobulin-deficient variant.
    Journal of the National Cancer Institute, 1988, Apr-20, Volume: 80, Issue:4

    Topics: Animals; beta 2-Microglobulin; Cell Survival; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; H-2 Ant

1988
Effects of differentiation inducing chemicals on in vivo malignancy and NK susceptibility of metastatic lymphoma cells.
    Cancer detection and prevention, 1988, Volume: 11, Issue:3-6

    Topics: Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cell Line; Cytotoxicity, Immu

1988
C-type particles produced by a permanent cell line from a leukemic pig. II. Physical, chemical, and serological characterization of the particles.
    Virology, 1974, Volume: 57, Issue:1

    Topics: Animals; Antigens, Viral; Bromodeoxyuridine; Cell Line; Centrifugation, Density Gradient; Chemical P

1974
DMSO and other combatants against bacteria isolated from leukemia and cancer patients.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Antitubercular Agents; Bacteria; Bacteriological Techniques; Blood Cells; Culture Media; Dimethyl Su

1967
C-type particles produced by a permanent cell line from a leukemic pig. I. Origin and properties of the host cells and some evidence for the occurrence of C-type-like particles.
    Virology, 1974, Volume: 57, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Dimethyl Sul

1974
Cytology and reactions of viable cells from malignant lymphoma.
    Cancer, 1969, Volume: 23, Issue:5

    Topics: Adult; Aged; Asparaginase; Cell Differentiation; Cell Transformation, Neoplastic; Dimethyl Sulfoxide

1969
Cytocidal effect of dimethyl sulfoxide on normal and leukemic lymphocytes.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Division; Dimethyl Sulfoxide; Hot Temperature; Humans; In Vitro

1967