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dimethyl sulfoxide and Epilepsy, Temporal Lobe

dimethyl sulfoxide has been researched along with Epilepsy, Temporal Lobe in 2 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).

Research Excerpts

ExcerptRelevanceReference
" Literature indicated that the highly efficient solvent dimethyl sulfoxide (DMSO) may have a confounding influence in epilepsy research, reporting both pro- and antiepileptic effects."8.31Dimethyl sulfoxide's impact on epileptiform activity in a mouse model of chronic temporal lobe epilepsy. ( Lieb, A; Mutti, A; Schwarzer, C; Widmann, M, 2023)
" Literature indicated that the highly efficient solvent dimethyl sulfoxide (DMSO) may have a confounding influence in epilepsy research, reporting both pro- and antiepileptic effects."4.31Dimethyl sulfoxide's impact on epileptiform activity in a mouse model of chronic temporal lobe epilepsy. ( Lieb, A; Mutti, A; Schwarzer, C; Widmann, M, 2023)
"Dimethyl sulfoxide (DMSO) is an amphipathic molecule widely used to solubilize water-insoluble compounds."1.39Antiepileptic effect of dimethyl sulfoxide in a rat model of temporal lobe epilepsy. ( Cannizzaro, C; Carletti, F; Ferraro, G; Rizzo, V; Sardo, P, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Widmann, M1
Lieb, A1
Mutti, A1
Schwarzer, C1
Carletti, F1
Ferraro, G1
Rizzo, V1
Cannizzaro, C1
Sardo, P1

Other Studies

2 other studies available for dimethyl sulfoxide and Epilepsy, Temporal Lobe

ArticleYear
Dimethyl sulfoxide's impact on epileptiform activity in a mouse model of chronic temporal lobe epilepsy.
    Epilepsy research, 2023, Volume: 197

    Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Female; Hipp

2023
Antiepileptic effect of dimethyl sulfoxide in a rat model of temporal lobe epilepsy.
    Neuroscience letters, 2013, Jun-24, Volume: 546

    Topics: Action Potentials; Animals; Anticonvulsants; Cerebellar Nuclei; Dimethyl Sulfoxide; Disease Models,

2013