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dimethyl sulfoxide and Encephalopathy, Toxic

dimethyl sulfoxide has been researched along with Encephalopathy, Toxic in 11 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Research Excerpts

ExcerptRelevanceReference
"Dimethyl sulfoxide (DMSO) is a cryoprotective agent used in storage of frozen stem cells in stem cell transplantation."1.46Neurotoxicity Associated With Dimethyl Sulfoxide Used in Allogeneic Stem Cell Transplantation. ( Ataseven, E; Güleryüz, H; Ören, H; Tüfekçi, Ö; Yilmaz, Ş, 2017)
"This experimental study suggested that DMSO has no toxic effect on the neural and arterial tissues of rats when it is slowly infused into the carotid artery."1.38Evaluation of the neurotoxicity of DMSO infused into the carotid artery of rat. ( Alhan, A; Bakar, B; Keskil, IS; Kilinc, K; Kose, EA; Sonal, S, 2012)
" In vitro toxicity studies in neurons and cancer cells and in vivo toxicity studies in rats were used to determine both the cancer chemotherapeutic and toxic effects of the identified compound."1.35Cisplatin and dimethyl sulfoxide react to form an adducted compound with reduced cytotoxicity and neurotoxicity. ( Benson, LM; Fauq, A; Fischer, SJ; Naylor, S; Windebank, AJ, 2008)
" A dose-response was examined with each of these solvents."1.32The effects of organic solvents on poly(ADP-ribose) polymerase-1 activity: implications for neurotoxicity. ( Banasik, M; Persad, AS; Stedeford, T; Strosznajder, RP; Tanaka, S; Ueda, K, 2004)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (63.64)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Zhang, J1
Li, Y1
Li, H1
Liu, A1
Cao, J1
Li, X1
Xia, N1
Zhang, Z1
Bai, J1
Zhang, H1
Huizenga, MN1
Forcelli, PA1
Ataseven, E1
Tüfekçi, Ö1
Yilmaz, Ş1
Güleryüz, H1
Ören, H1
Marcacci, G1
Corazzelli, G1
Becchimanzi, C1
Arcamone, M1
Capobianco, G1
Russo, F1
Frigeri, F1
Pinto, A1
Abdelkefi, A1
Lakhal, A1
Moojat, N1
Hamed, LB1
Fekih, J1
Ladeb, S1
Torjman, L1
Othman, TB1
Bakar, B1
Kose, EA1
Sonal, S1
Alhan, A1
Kilinc, K1
Keskil, IS1
Windrum, P1
Morris, TC1
Banasik, M1
Stedeford, T1
Strosznajder, RP1
Persad, AS1
Tanaka, S1
Ueda, K1
Bauwens, D1
Hantson, P1
Laterre, PF1
Michaux, L1
Latinne, D1
De Tourtchaninoff, M1
Cosnard, G1
Hernalsteen, D1
Júnior, AM1
Arrais, CA1
Saboya, R1
Velasques, RD1
Junqueira, PL1
Dulley, FL1
Fischer, SJ1
Benson, LM1
Fauq, A1
Naylor, S1
Windebank, AJ1

Other Studies

11 other studies available for dimethyl sulfoxide and Encephalopathy, Toxic

ArticleYear
Aspirin ameliorates the neurotoxicity of benzo[a]pyrene in mice and HT22 cells: Possible role of miRNA-mRNA network.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 178

    Topics: Animals; Aspirin; Benzo(a)pyrene; Dimethyl Sulfoxide; Mice; MicroRNAs; Neurotoxicity Syndromes; RNA,

2023
Neuroprotective Action of the CB1/2 Receptor Agonist, WIN 55,212-2, against DMSO but Not Phenobarbital-Induced Neurotoxicity in Immature Rats.
    Neurotoxicity research, 2019, Volume: 35, Issue:1

    Topics: Animals; Anticonvulsants; Benzoxazines; Brain; Cannabinoid Receptor Agonists; Cell Death; Dimethyl S

2019
Neurotoxicity Associated With Dimethyl Sulfoxide Used in Allogeneic Stem Cell Transplantation.
    Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:5

    Topics: Adolescent; Allografts; Cryopreservation; Cryoprotective Agents; Diagnosis, Differential; Dimethyl S

2017
DMSO-associated encephalopathy during autologous peripheral stem cell infusion: a predisposing role of preconditioning exposure to CNS-penetrating agents?
    Bone marrow transplantation, 2009, Volume: 44, Issue:2

    Topics: Adult; Central Nervous System; Cryopreservation; Dimethyl Sulfoxide; Female; Humans; Lymphoma, Non-H

2009
Severe neurotoxicity associated with dimethyl sulphoxide following PBSCT.
    Bone marrow transplantation, 2009, Volume: 44, Issue:5

    Topics: Cryoprotective Agents; Dimethyl Sulfoxide; Female; Hematopoietic Stem Cell Transplantation; Hematopo

2009
Evaluation of the neurotoxicity of DMSO infused into the carotid artery of rat.
    Injury, 2012, Volume: 43, Issue:3

    Topics: Animals; Brain; Carotid Arteries; Dimethyl Sulfoxide; Infusions, Intra-Arterial; Microscopy, Polariz

2012
Severe neurotoxicity because of dimethyl sulphoxide following peripheral blood stem cell transplantation.
    Bone marrow transplantation, 2003, Volume: 31, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cryopreservation; Cryopro

2003
The effects of organic solvents on poly(ADP-ribose) polymerase-1 activity: implications for neurotoxicity.
    Acta neurobiologiae experimentalis, 2004, Volume: 64, Issue:4

    Topics: Animals; Carbon Isotopes; Cattle; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Ethanol; Inh

2004
Recurrent seizure and sustained encephalopathy associated with dimethylsulfoxide-preserved stem cell infusion.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:11

    Topics: Cryopreservation; Dimethyl Sulfoxide; Fatal Outcome; Humans; Lymphoma, Large B-Cell, Diffuse; Male;

2005
Neurotoxicity associated with dimethylsulfoxide-preserved hematopoietic progenitor cell infusion.
    Bone marrow transplantation, 2008, Volume: 41, Issue:1

    Topics: Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Female; Hematopoietic Stem Cell Transpl

2008
Cisplatin and dimethyl sulfoxide react to form an adducted compound with reduced cytotoxicity and neurotoxicity.
    Neurotoxicology, 2008, Volume: 29, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Cisplatin; Dimethyl Sulfoxide; DNA;

2008