dimethyl sulfoxide has been researched along with Dementias, Transmissible in 4 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prion diseases are a group of infectious and fatal neurodegenerative disorders caused by the conformational conversion of a cellular prion protein (PrP) into its abnormal isoform PrP(Sc)." | 1.42 | Inhibitory effects of NAMI-A-like ruthenium complexes on prion neuropeptide fibril formation. ( Du, W; He, L; Wang, X; Zhao, C; Zhu, D, 2015) |
| "Dimethyl sulfoxide (DMSO) has been shown to reduce the accumulation of PrP(Sc) in scrapie-infected (ScN2a) cells, and to inhibit its aggregation in vitro." | 1.32 | Dimethyl sulfoxide delays PrP sc accumulation and disease symptoms in prion-infected hamsters. ( Avraham, I; Engelstein, R; Gabizon, R; Kahana, E; Shaked, GM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Zhu, D | 1 |
| Zhao, C | 1 |
| He, L | 1 |
| Du, W | 1 |
| Shaked, GM | 2 |
| Engelstein, R | 1 |
| Avraham, I | 2 |
| Kahana, E | 1 |
| Gabizon, R | 2 |
| Tcherkasskaya, O | 1 |
| Davidson, EA | 1 |
| Schmerr, MJ | 1 |
| Orser, CS | 1 |
| Meiner, Z | 1 |
| Taraboulos, A | 1 |
4 other studies available for dimethyl sulfoxide and Dementias, Transmissible
| Article | Year |
|---|---|
Inhibitory effects of NAMI-A-like ruthenium complexes on prion neuropeptide fibril formation.
Topics: Coordination Complexes; Copper; Dimethyl Sulfoxide; Humans; Organometallic Compounds; Oxidation-Redu | 2015 |
Dimethyl sulfoxide delays PrP sc accumulation and disease symptoms in prion-infected hamsters.
Topics: Animals; Brain; Cricetinae; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Injections, Intrap | 2003 |
Conformational biosensor for diagnosis of prion diseases.
Topics: Amyloid; Animals; Biosensing Techniques; Biotechnology; Brain; Circular Dichroism; Cricetinae; Deer; | 2005 |
Reconstitution of prion infectivity from solubilized protease-resistant PrP and nonprotein components of prion rods.
Topics: Analysis of Variance; Animals; Brain; Centrifugation, Density Gradient; Cricetinae; Dimethyl Sulfoxi | 2001 |