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dimethyl sulfoxide and Cystic Fibrosis

dimethyl sulfoxide has been researched along with Cystic Fibrosis in 6 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
"Airway secretions of cystic fibrosis patients were found to contain high concentrations of taurine, which decreased with antibiotic therapy during acute respiratory exacerbations."3.69Taurine modulation of hypochlorous acid-induced lung epithelial cell injury in vitro. Role of anion transport. ( Cantin, AM, 1994)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Shaughnessy, CA1
Zeitlin, PL1
Bratcher, PE1
Dreano, E1
Burgel, PR1
Hatton, A1
Bouazza, N1
Chevalier, B1
Macey, J1
Leroy, S1
Durieu, I1
Weiss, L1
Grenet, D1
Stremler, N1
Ohlmann, C1
Reix, P1
Porzio, M1
Roux Claude, P1
Rémus, N1
Douvry, B1
Montcouquiol, S1
Cosson, L1
Mankikian, J1
Languepin, J1
Houdouin, V1
Le Clainche, L1
Guillaumot, A1
Pouradier, D1
Tissot, A1
Priou, P1
Mély, L1
Chedevergne, F1
Lebourgeois, M1
Lebihan, J1
Martin, C1
Zavala, F1
Da Silva, J1
Lemonnier, L1
Kelly-Aubert, M1
Golec, A1
Foucaud, P1
Marguet, C1
Edelman, A1
Hinzpeter, A1
de Carli, P1
Girodon, E1
Sermet-Gaudelus, I1
Pranke, I1
Schwarzer, C1
Fu, Z1
Fischer, H1
Machen, TE1
Cantin, AM1
Trout, L1
King, M1
Feng, W1
Inglis, SK1
Ballard, ST1
Morello, JP1
Petäjä-Repo, UE1
Bichet, DG1
Bouvier, M1

Reviews

1 review available for dimethyl sulfoxide and Cystic Fibrosis

ArticleYear
Pharmacological chaperones: a new twist on receptor folding.
    Trends in pharmacological sciences, 2000, Volume: 21, Issue:12

    Topics: Animals; Cryoprotective Agents; Cystic Fibrosis; Diabetes Insipidus, Nephrogenic; Dimethyl Sulfoxide

2000

Other Studies

5 other studies available for dimethyl sulfoxide and Cystic Fibrosis

ArticleYear
Net benefit of ivacaftor during prolonged tezacaftor/elexacaftor exposure in vitro.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2022, Volume: 21, Issue:4

    Topics: Aminophenols; Benzodioxoles; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; D

2022
Theratyping cystic fibrosis patients to guide elexacaftor/tezacaftor/ivacaftor out-of-label prescription.
    The European respiratory journal, 2023, Volume: 62, Issue:4

    Topics: Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dimethyl Sulfoxide; Humans; Mu

2023
Redox-independent activation of NF-kappaB by Pseudomonas aeruginosa pyocyanin in a cystic fibrosis airway epithelial cell line.
    The Journal of biological chemistry, 2008, Oct-03, Volume: 283, Issue:40

    Topics: Catalase; Cell Line; Cystic Fibrosis; Dimethyl Sulfoxide; Drug Synergism; Flagellin; Free Radical Sc

2008
Taurine modulation of hypochlorous acid-induced lung epithelial cell injury in vitro. Role of anion transport.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Aged; Animals; Anions; Bronchitis; Cats; Ce

1994
Inhibition of airway liquid secretion and its effect on the physical properties of airway mucus.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: Acetylcholine; Animals; Bicarbonates; Bronchi; Chemical Phenomena; Chemistry, Physical; Chlorides; C

1998