Page last updated: 2024-10-18

dimethyl sulfoxide and Colonic Neoplasms

dimethyl sulfoxide has been researched along with Colonic Neoplasms in 36 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"A mouse colon cancer model was constructed by intraperitoneal injection of 10 mg/kg of Azoxymethane (AOM) and 2 % dextran sodium sulfate (DSS) in drinking water."1.91AC1Q3QWB inhibits colorectal cancer progression by modulating the immune response and balancing the structure of the intestinal microbiota. ( Chen, Y; Kang, C; Li, J; Liu, Z; Zhang, Q; Zhu, W, 2023)
"Dimethyl sulfoxide (DMSO) is a small molecule with polar, aprotic and amphiphilic properties."1.48Low dose dimethyl sulfoxide driven gross molecular changes have the potential to interfere with various cellular processes. ( Banerjee, S; Esenturk, O; Gurbanov, R; Sheraj, I; Solel, E; Tunçer, S, 2018)
"In this study, MSM was tested on colon cancer cells."1.43Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells. ( Aktan, F; Buyukbingol, Z; Hekmatshoar, Y; Karabay, AZ; Koc, A; Ozkan, T; Sunguroglu, A, 2016)
"Taxol did not inhibit pressure-induced colon cancer cell adhesion, but significantly lowered basal adhesion."1.33The role of the cytoskeleton in differentially regulating pressure-mediated effects on malignant colonocyte focal adhesion signaling and cell adhesion. ( Basson, MD; Thamilselvan, V, 2005)
"5-aminolevulinic acid (5-ALA) is a precursor in synthesis of endogenous porphyrins used to sensitize tumor tissues in photodynamic therapy (PDT)."1.32Enhancement of photodynamic therapy by use of aminolevulinic acid/glycolic acid drug mixture. ( Bronowicz, A; Oremek, G; Osiecka, BJ; Saleh, Y; Siewinski, M; Symonowicz, K; Ziolkowski, P, 2004)
"Our data show that (1) human colon cancer cells downregulate caspase 7 and, to a smaller extent, caspase 9 in vivo and (2) in vitro staurosporine-induced apoptosis of colonic cancer cells involves caspases 7 and 9."1.31Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma. ( Birg, F; Devilard, E; Jarry, A; Palmerini, F; Xerri, L, 2001)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19906 (16.67)18.7374
1990's12 (33.33)18.2507
2000's8 (22.22)29.6817
2010's7 (19.44)24.3611
2020's3 (8.33)2.80

Authors

AuthorsStudies
Zhu, W1
Li, J1
Chen, Y1
Liu, Z2
Zhang, Q1
Kang, C1
Storman, D1
Swierz, MJ1
Riemsma, RP2
Wolff, R2
Mitus, JW1
Pedziwiatr, M1
Kleijnen, J2
Bala, MM2
Tunçer, S1
Gurbanov, R1
Sheraj, I1
Solel, E1
Esenturk, O1
Banerjee, S1
Turan, I1
Demir, S1
Aliyazicioglu, R1
Kilinc, K1
Ozer Yaman, S1
Akbulut Cakiroglu, K1
Kanbolat, S1
Ayazoglu Demir, E1
Mentese, A1
Aliyazicioglu, Y1
Deger, O1
Karabay, AZ1
Koc, A1
Ozkan, T1
Hekmatshoar, Y1
Sunguroglu, A1
Aktan, F1
Buyukbingol, Z1
Xu, J1
Li, K1
Smith, RA1
Waterton, JC1
Zhao, P1
Ding, Z1
Does, MD1
Manning, HC1
Gore, JC1
Furumatsu, K1
Nishiumi, S1
Kawano, Y1
Ooi, M1
Yoshie, T1
Shiomi, Y1
Kutsumi, H1
Ashida, H1
Fujii-Kuriyama, Y1
Azuma, T1
Yoshida, M1
Zhang, F1
Koh, GY1
Hollingsworth, J1
Russo, PS1
Stout, RW1
Thamilselvan, V2
Li, W1
Sumpio, BE1
Basson, MD2
Da Violante, G1
Zerrouk, N1
Richard, I1
Provot, G1
Chaumeil, JC1
Arnaud, P1
Ziolkowski, P1
Osiecka, BJ1
Oremek, G1
Siewinski, M1
Symonowicz, K1
Saleh, Y1
Bronowicz, A1
Shakoori, A1
Mai, W1
Miyashita, K1
Yasumoto, K1
Takahashi, Y1
Ooi, A1
Kawakami, K1
Minamoto, T1
Cohn, I1
Kim, YS1
Tsao, D1
Siddiqui, B1
Whitehead, JS1
Arnstein, P1
Bennett, J1
Hicks, J1
Malik, Z1
Kostenich, G1
Roitman, L1
Ehrenberg, B1
Orenstein, A1
Lee, YJ1
Erdos, G1
Hou, ZZ1
Kim, SH1
Kim, JH1
Cho, JM1
Corry, PM1
Salim, AS2
Sharma, HW1
Sokoloski, JA1
Perez, JR1
Maltese, JY1
Sartorelli, AC1
Stein, CA1
Nichols, G1
Khaled, Z1
Telang, NT1
Narayanan, R1
Paulsen, JE1
Steffensen, IL1
Namork, E1
Hein, DW1
Alexander, J1
Lee, LF1
Schuerer-Maly, CC1
Lofquist, AK1
van Haaften-Day, C1
Ting, JP1
White, CM1
Martin, BK1
Haskill, JS1
Eckert, K1
Fuhrmann-Selter, T1
Maurer, HR1
Büttner, P1
Hanski, C1
Klussmann, E1
Wang, J1
Böhm, C1
Ogorek, D1
Hanski, ML1
Krüger-Krasagakes, S1
Eberle, J1
Schmitt-Gräff, A1
Riecken, EO1
Sheppard, BC1
Rutten, MJ1
Meichsner, CL1
Bacon, KD1
Leonetti, PO1
Land, J1
Crass, RC1
Trunkey, DD1
Deveney, KE1
Deveney, CW1
Tsuiji, H1
Nakatsugawa, S1
Ishigaki, T1
Irimura, T1
Parikh, AA1
Moon, MR1
Pritts, TA1
Fischer, JE1
Szabó, C1
Hasselgren, PO1
Salzman, AL1
Palmerini, F1
Devilard, E1
Jarry, A1
Birg, F1
Xerri, L1
Vashisht Gopal, YN1
Konuru, N1
Kondapi, AK1
Murphy, LD1
Valverius, EM1
Tsokos, M1
Mickley, LA1
Rosen, N1
Bates, SE1
Darling, D1
Tavassoli, M1
Linskens, MH1
Farzaneh, F1
O'Dwyer, PJ1
McCabe, DP1
Sickle-Santanello, BJ1
Woltering, EA1
Clausen, K1
Martin, EW1
Dibner, MD1
Ireland, KA1
Koerner, LA1
Dexter, DL1
Willoughby, HW1
Maughan, GB1
Tremblay, PC1
Wood, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Formulation of 5-aminolevulinic Acid With Dimethylsulfoxide in Photodynamic Therapy for Treatment of Actinic Keratosis[NCT01459393]Phase 3137 participants (Actual)Interventional2010-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for dimethyl sulfoxide and Colonic Neoplasms

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Electrocoagulation for liver metastases.
    The Cochrane database of systematic reviews, 2021, 01-28, Volume: 1

    Topics: Adult; Aged; Allopurinol; Cause of Death; Colonic Neoplasms; Dimethyl Sulfoxide; Electrocoagulation;

2021
Electro-coagulation for liver metastases.
    The Cochrane database of systematic reviews, 2013, May-31, Issue:5

    Topics: Allopurinol; Colonic Neoplasms; Dimethyl Sulfoxide; Electrocoagulation; Humans; Liver Neoplasms; Ran

2013

Trials

2 trials available for dimethyl sulfoxide and Colonic Neoplasms

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Scavengers of oxygen-derived free radicals prolong survival in advanced colonic cancer. A new approach.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1993, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Allopurinol; Analysis of Variance; Colonic Neoplasms; Dimethyl Sulfoxid

1993

Other Studies

32 other studies available for dimethyl sulfoxide and Colonic Neoplasms

ArticleYear
AC1Q3QWB inhibits colorectal cancer progression by modulating the immune response and balancing the structure of the intestinal microbiota.
    International immunopharmacology, 2023, Volume: 116

    Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Dim

2023
Low dose dimethyl sulfoxide driven gross molecular changes have the potential to interfere with various cellular processes.
    Scientific reports, 2018, 10-04, Volume: 8, Issue:1

    Topics: Algorithms; Colonic Neoplasms; Computer Simulation; Dimethyl Sulfoxide; DNA, Z-Form; Epithelial Cell

2018
Dimethyl Sulfoxide Extract of
    Nutrition and cancer, 2019, Volume: 71, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasm

2019
Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells.
    International journal of molecular sciences, 2016, Jul-15, Volume: 17, Issue:7

    Topics: Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Cell Survival; Colonic Neoplasms; Dimethyl S

2016
A comparative assessment of preclinical chemotherapeutic response of tumors using quantitative non-Gaussian diffusion MRI.
    Magnetic resonance imaging, 2017, Volume: 37

    Topics: Animals; Bayes Theorem; Colonic Neoplasms; Diffusion Magnetic Resonance Imaging; Dimethyl Sulfoxide;

2017
A role of the aryl hydrocarbon receptor in attenuation of colitis.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:9

    Topics: Animals; beta-Naphthoflavone; Cell Line, Tumor; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfa

2011
Reformulation of etoposide with solubility-enhancing rubusoside.
    International journal of pharmaceutics, 2012, Sep-15, Volume: 434, Issue:1-2

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Dimethyl S

2012
Sphingosine-1-phosphate stimulates human Caco-2 intestinal epithelial proliferation via p38 activation and activates ERK by an independent mechanism.
    In vitro cellular & developmental biology. Animal, 2002, Volume: 38, Issue:4

    Topics: Caco-2 Cells; Cell Division; Colonic Neoplasms; Dimethyl Sulfoxide; Dose-Response Relationship, Drug

2002
Evaluation of the cytotoxicity effect of dimethyl sulfoxide (DMSO) on Caco2/TC7 colon tumor cell cultures.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:12

    Topics: Biological Transport; Caco-2 Cells; Cell Death; Colonic Neoplasms; Dimethyl Sulfoxide; Drug Evaluati

2002
Enhancement of photodynamic therapy by use of aminolevulinic acid/glycolic acid drug mixture.
    Journal of experimental therapeutics & oncology, 2004, Volume: 4, Issue:2

    Topics: Adenocarcinoma; Administration, Cutaneous; Aged; Aminolevulinic Acid; Animals; Antineoplastic Combin

2004
The role of the cytoskeleton in differentially regulating pressure-mediated effects on malignant colonocyte focal adhesion signaling and cell adhesion.
    Carcinogenesis, 2005, Volume: 26, Issue:10

    Topics: Cell Adhesion; Cell Line, Tumor; Cells, Cultured; Colchicine; Colon; Colonic Neoplasms; Cytochalasin

2005
Inhibition of GSK-3 beta activity attenuates proliferation of human colon cancer cells in rodents.
    Cancer science, 2007, Volume: 98, Issue:9

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dimethyl Sulfoxide; Enzyme Inhibit

2007
Implantation in cancer of the colon.
    Surgery, gynecology & obstetrics, 1967, Volume: 124, Issue:3

    Topics: Animals; Antisepsis; Carcinoma, Brown-Pearce; Colonic Neoplasms; Dextrans; Dimethyl Sulfoxide; In Vi

1967
Effects of sodium butyrate and dimethylsulfoxide on biochemical properties of human colon cancer cells.
    Cancer, 1980, Mar-15, Volume: 45, Issue:5 Suppl

    Topics: Adenocarcinoma; Aminopeptidases; Butyrates; Cell Differentiation; Cell Division; Cell Line; Colonic

1980
Topical application of 5-aminolevulinic acid, DMSO and EDTA: protoporphyrin IX accumulation in skin and tumours of mice.
    Journal of photochemistry and photobiology. B, Biology, 1995, Volume: 28, Issue:3

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Colonic Neoplasms; Dimethyl Sulfoxide; Edetic

1995
Mechanism of quercetin-induced suppression and delay of heat shock gene expression and thermotolerance development in HT-29 cells.
    Molecular and cellular biochemistry, 1994, Aug-31, Volume: 137, Issue:2

    Topics: Base Sequence; Cell Line; Colonic Neoplasms; Dimethyl Sulfoxide; DNA-Binding Proteins; Dose-Response

1994
Differentiation of immortal cells inhibits telomerase activity.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Dec-19, Volume: 92, Issue:26

    Topics: Animals; Base Sequence; Butyrates; Butyric Acid; Calcitriol; Cell Differentiation; Cell Line; Cell N

1995
Effect of acetylator genotype on 3,2'-dimethyl-4-aminobiphenyl induced aberrant crypt foci in the colon of hamsters.
    Carcinogenesis, 1996, Volume: 17, Issue:3

    Topics: Acetylation; Acetyltransferases; Aminobiphenyl Compounds; Animals; Carcinogens; Chlorides; Colon; Co

1996
Taxol-dependent transcriptional activation of IL-8 expression in a subset of human ovarian cancer.
    Cancer research, 1996, Mar-15, Volume: 56, Issue:6

    Topics: Administration, Topical; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Cell Division;

1996
A colorimetric immunoassay for the detection of E-cadherin and carcinoembryonic antigen (CEA) expression on human colon carcinoma cell lines in vitro.
    Cancer letters, 1996, Jul-19, Volume: 105, Issue:1

    Topics: Cadherins; Carcinoembryonic Antigen; Carcinoma; Colonic Neoplasms; Dimethyl Sulfoxide; Humans; Immun

1996
Fucosyltransferase III and sialyl-Le(x) expression correlate in cultured colon carcinoma cells but not in colon carcinoma tissue.
    Glycoconjugate journal, 1996, Volume: 13, Issue:5

    Topics: Antibodies, Monoclonal; Blotting, Northern; Butyrates; Butyric Acid; Colonic Neoplasms; Dimethyl Sul

1996
Effects of paclitaxel on the growth of normal, polyposis, and cancerous human colonic epithelial cells.
    Cancer, 1999, Apr-01, Volume: 85, Issue:7

    Topics: Adenomatous Polyposis Coli; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Sub

1999
Malignant and other properties of human colon carcinoma cells after suppression of sulfomucin production in vitro.
    Clinical & experimental metastasis, 1999, Volume: 17, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Base Sequence; Blotting, Western; Cell Adhesion; Cell Division; Col

1999
IL-1beta induction of NF-kappaB activation in human intestinal epithelial cells is independent of oxyradical signaling.
    Shock (Augusta, Ga.), 2000, Volume: 13, Issue:1

    Topics: Adenocarcinoma; Antioxidants; Cell Nucleus; Cell Survival; Colonic Neoplasms; Dimethyl Sulfoxide; DN

2000
Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma.
    Human pathology, 2001, Volume: 32, Issue:5

    Topics: Apoptosis; Biomarkers, Tumor; Blotting, Western; Caspase 7; Caspase 8; Caspase 9; Caspase Inhibitors

2001
Topoisomerase II antagonism and anticancer activity of coordinated derivatives of [RuCl(2)(C(6)H(6))(dmso)].
    Archives of biochemistry and biophysics, 2002, May-01, Volume: 401, Issue:1

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Colonic Neoplasms; Dimethyl Sulfoxi

2002
Removing oxygen-derived free radicals delays hepatic metastases and prolongs survival in colonic cancer. A study in the rat.
    Oncology, 1992, Volume: 49, Issue:1

    Topics: 1,2-Dimethylhydrazine; Allopurinol; Animals; Carcinogens; Colonic Neoplasms; Dimethyl Sulfoxide; Dim

1992
Modulation of EGF receptor expression by differentiating agents in human colon carcinoma cell lines.
    Cancer communications, 1990, Volume: 2, Issue:10

    Topics: Alkaline Phosphatase; Blotting, Northern; Butyrates; Butyric Acid; Cell Differentiation; Cell Divisi

1990
DMSO induced modulation of c-myc steady-state RNA levels in a variety of different cell lines.
    Oncogene, 1989, Volume: 4, Issue:2

    Topics: Cell Differentiation; Colonic Neoplasms; Dimethyl Sulfoxide; Gene Amplification; Humans; Leukemia, P

1989
Use of polar solvents in chemoprevention of 1,2-dimethylhydrazine-induced colon cancer.
    Cancer, 1988, Sep-01, Volume: 62, Issue:5

    Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethyl Sulfoxide; Dimethylhydrazin

1988
Polar solvent-induced changes in membrane lipid lateral diffusion in human colon cancer cells.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: Butyrates; Butyric Acid; Cell Line; Colonic Neoplasms; Diffusion; Dimethyl Sulfoxide; Dimethylformam

1985
Determination of individual human tumour sensitivity to antitumour agents by tissue-slice incubation.
    Canadian journal of surgery. Journal canadien de chirurgie, 1971, Volume: 14, Issue:6

    Topics: Adenine; Adenocarcinoma; Antineoplastic Agents; Carbon Isotopes; Carcinoma; Colonic Neoplasms; Cultu

1971