dimethyl sulfoxide has been researched along with Cleft Palate in 7 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Cleft Palate: Congenital fissure of the soft and/or hard palate, due to faulty fusion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Secalonic acid-D (SAD) is a teratogenic mycotoxin inducing cleft palate (CP) in the offspring of the exposed mice by reducing palatal shelf size secondary to reduced proliferation of the palatal mesenchymal (PM) cells." | 7.72 | Relevance of the palatal protein kinase A pathway to the pathogenesis of cleft palate by secalonic acid D in mice. ( Balasubramanian, G; Dhulipala, VC; Hanumegowda, UM; Reddy, CS, 2004) |
| "Secalonic acid-D (SAD) is a teratogenic mycotoxin inducing cleft palate (CP) in the offspring of the exposed mice by reducing palatal shelf size secondary to reduced proliferation of the palatal mesenchymal (PM) cells." | 3.72 | Relevance of the palatal protein kinase A pathway to the pathogenesis of cleft palate by secalonic acid D in mice. ( Balasubramanian, G; Dhulipala, VC; Hanumegowda, UM; Reddy, CS, 2004) |
| "Dose-response of the teratogenic effect of caffeine (CA) and the potential role of facial hematomas in the pathogenesis of caffeine-induced cleft palate were investigated using CD1 mice treated with 150, 200, or 250 mg CA/kg i." | 3.69 | Interaction of dimethylsulfoxide and arachidonic acid with the teratogenic effects of caffeine in mice. ( Brimer, GE; Fraipier, BL; Frappier, BL; Reddy, CS; Reddy, RV, 1994) |
| " on day 11 of pregnancy in either 5% (w/v) NaHCO3 or 20% (v/v) dimethyl sulfoxide (DMSO) in NaHCO3." | 3.68 | Role of maternal plasma corticosterone elevation in the teratogenicity of secalonic acid D in mice. ( Eldeib, MM; Reddy, CS, 1990) |
| "The H-2 region of mouse chromosome 17 is known to include one or more genes that affect susceptibility to cortisone-induced cleft palate." | 3.67 | Recombinants in the H-2S/H-2D interval of mouse chromosome 17 define the map position of a gene for cleft palate susceptibility. ( Gasser, DL; Goldman, AS; Trammell, MA; Yadvish, KN, 1988) |
| " The vehicle used in RA dosing was also shown to be a major factor in the incidence of RA-induced cleft palate." | 1.28 | Etiology of retinoic acid-induced cleft palate varies with the embryonic stage. ( Abbott, BD; Birnbaum, LS; Harris, MW, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhulipala, VC | 1 |
| Hanumegowda, UM | 1 |
| Balasubramanian, G | 1 |
| Reddy, CS | 4 |
| Reddy, RV | 1 |
| Frappier, BL | 1 |
| Brimer, GE | 1 |
| Fraipier, BL | 1 |
| Eldeib, MM | 2 |
| Abbott, BD | 1 |
| Harris, MW | 1 |
| Birnbaum, LS | 1 |
| Gasser, DL | 1 |
| Yadvish, KN | 1 |
| Trammell, MA | 1 |
| Goldman, AS | 1 |
| Courtney, KD | 1 |
| Gaylor, DW | 1 |
| Hogan, MD | 1 |
| Falk, HL | 1 |
| Bates, RR | 1 |
| Mitchell, I | 1 |
7 other studies available for dimethyl sulfoxide and Cleft Palate
| Article | Year |
|---|---|
Relevance of the palatal protein kinase A pathway to the pathogenesis of cleft palate by secalonic acid D in mice.
Topics: Animals; Blotting, Western; Catalysis; Cell Division; Cell Nucleus; Cleft Palate; Cyclic AMP Respons | 2004 |
Interaction of dimethylsulfoxide and arachidonic acid with the teratogenic effects of caffeine in mice.
Topics: Abnormalities, Drug-Induced; Animals; Arachidonic Acid; Caffeine; Cleft Palate; Corticosterone; Dime | 1994 |
Role of maternal plasma corticosterone elevation in the teratogenicity of secalonic acid D in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Corticosterone; Dimethyl Sulfoxide; Dose-Respons | 1990 |
Etiology of retinoic acid-induced cleft palate varies with the embryonic stage.
Topics: Animals; Cleft Palate; Corn Oil; Dimethyl Sulfoxide; Epidermal Growth Factor; Gestational Age; Mice; | 1989 |
Mechanism of dimethylsulfoxide protection against the teratogenicity of secalonic acid D in mice.
Topics: Animals; Body Weight; Cleft Palate; Dimethyl Sulfoxide; Female; Fetal Resorption; Fetus; Mice; Mycot | 1988 |
Recombinants in the H-2S/H-2D interval of mouse chromosome 17 define the map position of a gene for cleft palate susceptibility.
Topics: Alleles; Animals; Chromosome Mapping; Chromosomes; Cleft Palate; Cortisone; Crossing Over, Genetic; | 1988 |
Teratogenic evaluation of 2,4,5-T.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Dimethyl Sulfoxide; Female; Fetal Death; Fetus; | 1970 |