dimethyl sulfoxide has been researched along with Classic Globoid Cell Leukodystrophy in 2 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Krabbe's disease (globoid cell leukodystrophy) is a progressive cerebral degenerative disease of infancy characterized by severe myelin loss and the presence of globoid bodies in the white matter." | 1.30 | Tissue culture model of Krabbe's disease: psychosine cytotoxicity in rat oligodendrocyte culture. ( Cho, KH; Kim, MW; Kim, SU, 1997) |
| "Psychosine cytotoxicity was tested as to its effects on rat C6 glioma cells." | 1.28 | Psychosine cytotoxicity toward rat C6 glioma cells and the protective effects of phorbol ester and dimethylsulfoxide: implications for therapy in Krabbe disease. ( Eto, Y; Kim, SU; Sugama, S; Yamamoto, H, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cho, KH | 1 |
| Kim, MW | 1 |
| Kim, SU | 2 |
| Sugama, S | 1 |
| Eto, Y | 1 |
| Yamamoto, H | 1 |
2 other studies available for dimethyl sulfoxide and Classic Globoid Cell Leukodystrophy
| Article | Year |
|---|---|
Tissue culture model of Krabbe's disease: psychosine cytotoxicity in rat oligodendrocyte culture.
Topics: Albumins; Animals; Brain; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; Hypoglycemic Agents; I | 1997 |
Psychosine cytotoxicity toward rat C6 glioma cells and the protective effects of phorbol ester and dimethylsulfoxide: implications for therapy in Krabbe disease.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Cell Count; Dimethyl Sulfoxide; Glial Fibrillar | 1991 |