Page last updated: 2024-10-18

dimethyl sulfoxide and Cataract

dimethyl sulfoxide has been researched along with Cataract in 17 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" Whether long-term use of oral contraceptives would produce ocular complications was queried by Cogan."2.35Effects of drugs on the lens. ( Paterson, CA, 1971)
"Cataract is common in the dog."1.26Lens opacities in the dog as models for human eye disease. ( Barnett, KC, 1982)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199016 (94.12)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, M1
Shoeb, M1
Liu, P1
Xiao, T1
Hogan, D1
Wong, IG1
Campbell, GA1
Ansari, NH1
Barnett, KC1
Rubin, LF1
Rossa, V2
Kluxen, G2
Koch, HR1
Hockwin, O1
Gehring, PJ1
Kinoshita, JH1
Rengstorff, RH1
Petrali, JP1
Sim, VM1
Bernstein, HN1
Paterson, CA1
Van Heyningen, R1
Harding, JJ1
Stewart, BH1
Branson, AC1
Hewitt, CB1
Kiser, WS1
Straffon, RA1
Gordon, DM1
Hagemann, RF2
Evans, TC2
Riley, EF2
Heywood, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Treatment of Refractory Bladder Pain Syndrome With Dimethyl Sulfoxide (DMSO) Alone and DMSO as a Carrier Molecule for Botulinum Toxin A Instillation.[NCT03103594]Early Phase 12 participants (Actual)Interventional2015-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for dimethyl sulfoxide and Cataract

ArticleYear
Toxicity of dimethyl sulfoxide, alone and in combination.
    Annals of the New York Academy of Sciences, 1975, Jan-27, Volume: 243

    Topics: Animals; Cataract; Dimethyl Sulfoxide; Drug Combinations; Drug-Related Side Effects and Adverse Reac

1975
The cataractogenic activity of chemical agents.
    CRC critical reviews in toxicology, 1971, Volume: 1, Issue:1

    Topics: Adrenal Cortex Hormones; Alkylating Agents; Aniline Compounds; Carbohydrates; Cataract; Chemical Phe

1971
Mechanisms initiating cataract formation. Proctor Lecture.
    Investigative ophthalmology, 1974, Volume: 13, Issue:10

    Topics: Acetates; Adenosine Triphosphatases; Aged; Alcohol Oxidoreductases; Animals; Biological Transport; C

1974
Some iatrogenic ocular diseases from systemically administered drugs.
    International ophthalmology clinics, 1970,Fall, Volume: 10, Issue:3

    Topics: Animals; Cataract; Cats; Chemical Phenomena; Chemistry; Chloramphenicol; Chloroquine; Chlorpromazine

1970
Effects of drugs on the lens.
    International ophthalmology clinics, 1971, Volume: 11, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Animals; Antineoplastic Agents; Carbohydrates; Cataract; Contra

1971

Other Studies

12 other studies available for dimethyl sulfoxide and Cataract

ArticleYear
Topical metal chelation therapy ameliorates oxidation-induced toxicity in diabetic cataract.
    Journal of toxicology and environmental health. Part A, 2011, Volume: 74, Issue:6

    Topics: Administration, Topical; Aldehydes; Animals; Cataract; Cell Proliferation; Chelating Agents; Chelati

2011
Lens opacities in the dog as models for human eye disease.
    Transactions of the ophthalmological societies of the United Kingdom, 1982, Volume: 102 Pt 3

    Topics: Animals; Cataract; Dimethyl Sulfoxide; Disease Models, Animal; Dog Diseases; Dogs

1982
Toxic lenses--how they compare with senile cataracts.
    Developments in ophthalmology, 1989, Volume: 17

    Topics: Animals; Cataract; Dimethyl Sulfoxide; Male; Naphthalenes; Rabbits

1989
[Significance of experimental cataracts for the development of senile cataracts exemplified by naphthalene and dimethyl sulfoxide-induced lens opacities].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1988, Volume: 85, Issue:4

    Topics: Animals; Cataract; Dimethyl Sulfoxide; Disease Models, Animal; Lens, Crystalline; Naphthalenes; Rabb

1988
[Iatrogenic cataracts].
    Medizinische Klinik, 1974, Oct-18, Volume: 69, Issue:42

    Topics: Aged; Anesthetics, Local; Anthelmintics; Azathioprine; Cataract; Chloroquine; Chlorpromazine; Dimeth

1974
Cataracts induced in guinea pigs by acetone, cyclohexanone, and dimethyl sulfoxide.
    American journal of optometry and archives of American Academy of Optometry, 1972, Volume: 49, Issue:4

    Topics: Acetone; Animals; Cataract; Cyclohexanes; Dimethyl Sulfoxide; Female; Guinea Pigs; Ketones; Lens, Cr

1972
Some changes in the lens of the dimethylsulphoxide-fed rabbit.
    Experimental eye research, 1972, Volume: 14, Issue:2

    Topics: Amino Acids; Animals; Cataract; Chemical Precipitation; Crystallins; Dimethyl Sulfoxide; Disease Mod

1972
The treatment of patients with interstitial cystitis, with special reference to intravesical DMSO.
    Transactions of the American Association of Genito-Urinary Surgeons, 1971, Volume: 63

    Topics: Animals; Cataract; Cystitis; Dimethyl Sulfoxide; Dogs; Eye; Female; Humans; Male; Ophthalmoscopy; Ti

1971
Dimethyl sulfoxide in ophthalmology, with especial reference to possible toxic effects.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Adolescent; Adult; Aged; Cataract; Conjunctivitis; Dimethyl Sulfoxide; Eye Diseases; Female; Glaucom

1967
Modification of radiation effect on the eye by topical application of dimethyl sulfoxide.
    Radiation research, 1970, Volume: 44, Issue:2

    Topics: Animals; Cataract; Cornea; Dimethyl Sulfoxide; Female; Male; Mercaptoethylamines; Mice; Radiation Ef

1970
Drug-induced lenticular lesions in the dog.
    The British veterinary journal, 1971, Volume: 127, Issue:7

    Topics: Acute Disease; Animals; Cataract; Chronic Disease; Dimethyl Sulfoxide; Dogs; Lens, Crystalline; Micr

1971
Anomalous effects of dimethyl sulfoxide on the response of the mouse lens and cornea to x-irradiation: "protection" of lens and "sensitization" of cornea.
    Radiology, 1969, Volume: 92, Issue:1

    Topics: Animals; Cataract; Cornea; Dimethyl Sulfoxide; Female; Lens, Crystalline; Mice; Radiation Effects; R

1969