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dimethyl sulfoxide and Carcinoma, Small Cell

dimethyl sulfoxide has been researched along with Carcinoma, Small Cell in 5 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)

Research Excerpts

ExcerptRelevanceReference
"A low concentration of differentiation inducers such as dimethylsulphoxide (DMSO), sodium butyrate, hexamethylene bisacetamide and sodium phenylacetate greatly enhanced the antiproliferative effect in vitro and in vivo of interferon alpha (IFN-alpha) to several human lung adenocarcinoma cells."3.69Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents. ( Goto, I; Honma, Y; Yamamoto-Yamaguchi, Y, 1996)
" The SCLC cell lines, NCI-H69, NCI-H146 and NCI-H209, showed a dose-response (tested between 0."1.31Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571. ( Griffin, JD; Healy, ME; Johnson, BE; Lin, J; Maulik, G; Salgia, R; Sattler, M; Stiles, CD; Verma, S; Wang, WL, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goto, I1
Yamamoto-Yamaguchi, Y1
Honma, Y1
Nakae, T1
Horai, T1
Imamura, F1
Akedo, H1
Higashino, K1
Wang, WL1
Healy, ME1
Sattler, M1
Verma, S1
Lin, J1
Maulik, G1
Stiles, CD1
Griffin, JD1
Johnson, BE1
Salgia, R1
Giaccone, G1
Broers, J1
Jensen, S1
Fridman, RI1
Linnoila, R1
Gazdar, AF1
Munker, M1
Munker, R1
Saxton, RE1
Koeffler, HP1

Other Studies

5 other studies available for dimethyl sulfoxide and Carcinoma, Small Cell

ArticleYear
Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents.
    British journal of cancer, 1996, Volume: 74, Issue:4

    Topics: Acetamides; Adenocarcinoma; Alkaline Phosphatase; Animals; Antineoplastic Agents; Biomarkers; Butyra

1996
Expression of cathepsin B in small cell lung carcinoma cells in relation to in vitro invasiveness.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1998, Volume: 19, Issue:2

    Topics: Carcinoma, Small Cell; Cathepsin B; Cell Aggregation; Cell Division; Cell Line; Cells, Cultured; Dim

1998
Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571.
    Oncogene, 2000, Jul-20, Volume: 19, Issue:31

    Topics: Animals; Antineoplastic Agents; Benzamides; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; C

2000
Increased expression of differentiation markers can accompany laminin-induced attachment of small cell lung cancer cells.
    British journal of cancer, 1992, Volume: 66, Issue:3

    Topics: Acetamides; Actins; Bucladesine; Carcinoma, Small Cell; Cell Adhesion; Cell Differentiation; Cell Di

1992
Effect of recombinant monokines, lymphokines, and other agents on clonal proliferation of human lung cancer cell lines.
    Cancer research, 1987, Aug-01, Volume: 47, Issue:15

    Topics: Calcitriol; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Di

1987