Page last updated: 2024-10-18

dimethyl sulfoxide and Canine Diseases

dimethyl sulfoxide has been researched along with Canine Diseases in 28 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Research Excerpts

ExcerptRelevanceReference
"To assess the initial therapy of chronic superficial keratitis (CSK) in dogs with the use of dexamethasone and cyclosporine/ dimethyl sulfoxide combination eye drops."9.41Clinical study on the application of dexamethasone and cyclosporine/dimethyl sulfoxide combination eye drops in the initial therapy of chronic superficial keratitis in dogs. ( Balicka, A; Balicki, I; Szadkowski, M; Zwolska, J, 2021)
"The objective of this study was to assess the treatment of chronic superficial keratitis (CSK) in dogs with the use of tacrolimus and DMSO."9.16Clinical study on the application of tacrolimus and DMSO in the treatment of chronic superficial keratitis in dogs. ( Balicki, I, 2012)
"To determine whether thalidomide inhibits the growth of primary and pulmonary metastatic canine osteosarcoma in mice after xenotransplantation."7.72Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice. ( Baldwin, JM; Detrisac, CJ; Farese, JP; Fox, LE; Roberts, SL; Van Gilder, JM, 2004)
"To assess the initial therapy of chronic superficial keratitis (CSK) in dogs with the use of dexamethasone and cyclosporine/ dimethyl sulfoxide combination eye drops."5.41Clinical study on the application of dexamethasone and cyclosporine/dimethyl sulfoxide combination eye drops in the initial therapy of chronic superficial keratitis in dogs. ( Balicka, A; Balicki, I; Szadkowski, M; Zwolska, J, 2021)
" As matrix metalloproteinase-9 is likewise acutely elevated in dogs with naturally occurring spinal cord injuries, we evaluated efficacy of GM6001 solubilized in dimethyl sulfoxide in this second species."5.19Efficacy of a metalloproteinase inhibitor in spinal cord injured dogs. ( Cohen, ND; Fajt, VR; Fandel, TM; Heller, M; Kerwin, SC; Levine, GJ; Levine, JM; Modestino, A; Noble-Haeusslein, LJ; Trivedi, AA; Werb, Z, 2014)
"The objective of this study was to assess the treatment of chronic superficial keratitis (CSK) in dogs with the use of tacrolimus and DMSO."5.16Clinical study on the application of tacrolimus and DMSO in the treatment of chronic superficial keratitis in dogs. ( Balicki, I, 2012)
"To determine whether thalidomide inhibits the growth of primary and pulmonary metastatic canine osteosarcoma in mice after xenotransplantation."3.72Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice. ( Baldwin, JM; Detrisac, CJ; Farese, JP; Fox, LE; Roberts, SL; Van Gilder, JM, 2004)
"In dogs, gastric dilatation-volvulus (GDV) is characterized by cardiogenic shock, with resulting hypoperfusion."1.28Treatment of reperfusion injury in dogs with experimentally induced gastric dilatation-volvulus. ( Arkin, TE; Badylak, SF; Hiles, MC; Lantz, GC, 1992)
"Uveitis was induced in dogs by intracameral injection of canine lens protein."1.28Effects of lipoxygenase inhibitors in a model of lens-induced uveitis in dogs. ( Baker, JS; Chiou, GC; Dziezyc, J; Millichamp, NJ; Rohde, BH, 1989)
"Cataract is common in the dog."1.26Lens opacities in the dog as models for human eye disease. ( Barnett, KC, 1982)
"Acute spinal cord trauma was induced by the Allen method at T12 in 48 dogs."1.26Combined pharmacologic and surgical treatments for acute spinal cord trauma. ( Lumb, WV; Rucker, NC; Scott, RJ, 1981)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199017 (60.71)18.7374
1990's3 (10.71)18.2507
2000's1 (3.57)29.6817
2010's6 (21.43)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Balicki, I2
Szadkowski, M1
Balicka, A1
Zwolska, J1
Beknazarova, M1
Millsteed, S1
Robertson, G1
Whiley, H1
Ross, K1
Levine, JM1
Cohen, ND1
Heller, M1
Fajt, VR1
Levine, GJ1
Kerwin, SC1
Trivedi, AA1
Fandel, TM1
Werb, Z1
Modestino, A1
Noble-Haeusslein, LJ1
Kau, S1
Miller, I1
Tichy, A1
Gabriel, C1
Khan, SA1
McLean, MK1
Gwaltney-Brant, S1
Brim, TA1
Center, V1
Wynn, SG1
Springs, S1
Gray, LF1
Brown, LP1
Farese, JP1
Fox, LE1
Detrisac, CJ1
Van Gilder, JM1
Roberts, SL1
Baldwin, JM1
Barnett, KC1
Gruys, E1
Sijens, RJ1
Biewenga, WJ1
Harris, AM1
Clark, KA1
Rucker, NC1
Lumb, WV1
Scott, RJ1
Loeven, KO1
Doliger, S1
Delverdier, M1
Moré, J1
Longeart, L1
Régnier, A1
Magnol, JP1
Neu, H1
Meutstege, FJ1
Parker, AJ1
Smith, CW1
Koller, LD1
Averkin, E1
Kilian, J1
O Brien, T1
Sickles, J1
Lantz, GC1
Badylak, SF1
Hiles, MC1
Arkin, TE1
Dziezyc, J1
Millichamp, NJ1
Rohde, BH1
Baker, JS1
Chiou, GC1
Heymann, LD1
Spyridakis, L1
Brown, S1
Barsanti, J1
Hardie, EM1
Carlton, B1
Lee, J1
Prole, JH1
Knowles, RP1

Reviews

2 reviews available for dimethyl sulfoxide and Canine Diseases

ArticleYear
Dubious effect of dimethylsulphoxide (DMSO) therapy on amyloid deposits and amyloidosis.
    Veterinary research communications, 1981, Volume: 5, Issue:1

    Topics: Amyloid; Amyloidosis; Animals; Caseins; Cricetinae; Dimethyl Sulfoxide; Disease Models, Animal; Dog

1981
[The use of analgesic and antiphlogistic agents in small animals (author's transl)].
    Tijdschrift voor diergeneeskunde, 1975, May-01, Volume: 100, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Biotransform

1975

Trials

3 trials available for dimethyl sulfoxide and Canine Diseases

ArticleYear
Clinical study on the application of dexamethasone and cyclosporine/dimethyl sulfoxide combination eye drops in the initial therapy of chronic superficial keratitis in dogs.
    Polish journal of veterinary sciences, 2021, Volume: 24, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Chronic Disease; Cyclosporine; Dexamethasone; Dimethyl Sulfoxide;

2021
Efficacy of a metalloproteinase inhibitor in spinal cord injured dogs.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Animals; Dimethyl Sulfoxide; Dipeptides; Dog Diseases; Dogs; Double-Blind Method; Drug Therapy, Comb

2014
Clinical study on the application of tacrolimus and DMSO in the treatment of chronic superficial keratitis in dogs.
    Polish journal of veterinary sciences, 2012, Volume: 15, Issue:4

    Topics: Animals; Chronic Disease; Dimethyl Sulfoxide; Dog Diseases; Dogs; Female; Free Radical Scavengers; I

2012

Other Studies

23 other studies available for dimethyl sulfoxide and Canine Diseases

ArticleYear
Validation of DESS as a DNA Preservation Method for the Detection of Strongyloides spp. in Canine Feces.
    International journal of environmental research and public health, 2017, 06-09, Volume: 14, Issue:6

    Topics: Animals; Dimethyl Sulfoxide; DNA, Helminth; Dog Diseases; Dogs; Edetic Acid; Feces; Humans; Real-Tim

2017
S100A4 (metastasin) positive mesenchymal canine mammary tumour spheroids reduce Tenascin C synthesis under DMSO exposure in vitro.
    Veterinary and comparative oncology, 2017, Volume: 15, Issue:4

    Topics: Animals; Blotting, Western; Dimethyl Sulfoxide; Dog Diseases; Dogs; Female; Mammary Neoplasms, Anima

2017
Accidental overdosage of joint supplements in dogs.
    Journal of the American Veterinary Medical Association, 2010, Mar-01, Volume: 236, Issue:5

    Topics: Animals; Chemical and Drug Induced Liver Injury; Creatine; Dietary Supplements; Dimethyl Sulfoxide;

2010
More on accidental overdosage of joint supplements.
    Journal of the American Veterinary Medical Association, 2010, May-15, Volume: 236, Issue:10

    Topics: Animals; Dietary Supplements; Dimethyl Sulfoxide; Dog Diseases; Dogs; Drug Industry; Drug Overdose;

2010
Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice.
    American journal of veterinary research, 2004, Volume: 65, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Dimethyl Sulfoxide; Dog Diseases; Dogs; Dose-Response Relationship

2004
Lens opacities in the dog as models for human eye disease.
    Transactions of the ophthalmological societies of the United Kingdom, 1982, Volume: 102 Pt 3

    Topics: Animals; Cataract; Dimethyl Sulfoxide; Disease Models, Animal; Dog Diseases; Dogs

1982
DMSO therapy for posterior paralysis.
    Journal of the American Veterinary Medical Association, 1982, Apr-01, Volume: 180, Issue:7

    Topics: Animals; Dexamethasone; Dimethyl Sulfoxide; Dog Diseases; Dogs; Female; Hindlimb; Paralysis; Vitamin

1982
Management of poisonous snakebites in dogs and cats.
    Modern veterinary practice, 1981, Volume: 62, Issue:6

    Topics: Animals; Antivenins; Cat Diseases; Cats; Dimethyl Sulfoxide; Dog Diseases; Dogs; Snake Bites; Snakes

1981
Combined pharmacologic and surgical treatments for acute spinal cord trauma.
    American journal of veterinary research, 1981, Volume: 42, Issue:7

    Topics: Acute Disease; Animals; Dexamethasone; Dimethyl Sulfoxide; Dog Diseases; Dogs; Female; Glucose; Male

1981
Hepatic amyloidosis in two Chinese Shar Pei dogs.
    Journal of the American Veterinary Medical Association, 1994, Apr-15, Volume: 204, Issue:8

    Topics: Amyloidosis; Animals; Breeding; Colchicine; Dimethyl Sulfoxide; Dog Diseases; Dogs; Female; Fever; L

1994
Histochemical study of cutaneous mucins in hypothyroid dogs.
    Veterinary pathology, 1995, Volume: 32, Issue:6

    Topics: Animals; Biopsy; Coloring Agents; Connective Tissue; Dimethyl Sulfoxide; Dog Diseases; Dogs; Female;

1995
[SOFAN, a DMSO-containing dermatologic agent in small-animal practice].
    Berliner und Munchener tierarztliche Wochenschrift, 1975, Sep-15, Volume: 88, Issue:18

    Topics: Animals; Cat Diseases; Cats; Dermatologic Agents; Dexamethasone; Dimethyl Sulfoxide; Dog Diseases; D

1975
Lack of functional recovery from spinal cord trauma following dimethylsulphoxide and epsilon amino caproic acid therapy in dogs.
    Research in veterinary science, 1979, Volume: 27, Issue:2

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Dimethyl Sulfoxide; Dog Diseases; Dogs; Spinal Cord Inju

1979
DMSO for dogs.
    Modern veterinary practice, 1978, Volume: 59, Issue:6

    Topics: Animals; Cysts; Dimethyl Sulfoxide; Dog Diseases; Dogs; Granuloma; Otitis Externa; Skin Diseases; Sn

1978
Clinical application of DMSO by veterinarians in Oregon & Washington.
    Veterinary medicine, small animal clinician : VM, SAC, 1976, Volume: 71, Issue:5

    Topics: Animal Diseases; Animals; Cat Diseases; Cats; Cattle; Cattle Diseases; Dimethyl Sulfoxide; Dog Disea

1976
Experimental design of clinical trials testing the efficacy of 90% DMSO solution in injuries to the musculoskeletal system in the dog.
    Veterinary medicine, small animal clinician : VM, SAC, 1975, Volume: 70, Issue:2

    Topics: Animals; Arthritis; Dimethyl Sulfoxide; Dog Diseases; Dogs; Sprains and Strains

1975
Treatment of reperfusion injury in dogs with experimentally induced gastric dilatation-volvulus.
    American journal of veterinary research, 1992, Volume: 53, Issue:9

    Topics: Animals; Deferoxamine; Dimethyl Sulfoxide; Disease Models, Animal; Dog Diseases; Dogs; Gastric Dilat

1992
Effects of lipoxygenase inhibitors in a model of lens-induced uveitis in dogs.
    American journal of veterinary research, 1989, Volume: 50, Issue:11

    Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Dog Diseases; Dogs; Intraocular Pressure; Lipox

1989
Dimethyl sulfoxide.
    Journal of the American Veterinary Medical Association, 1986, Jun-15, Volume: 188, Issue:12

    Topics: Animals; Dimethyl Sulfoxide; Dog Diseases; Dogs; Spinal Cord Injuries

1986
Amyloidosis in a dog: treatment with dimethylsulfoxide.
    Journal of the American Veterinary Medical Association, 1986, Sep-15, Volume: 189, Issue:6

    Topics: Amyloidosis; Animals; Dimethyl Sulfoxide; Dog Diseases; Dogs; Kidney Glomerulus; Male

1986
Dimethyl sulfoxide (DMSO) in experimental treatment of snakebite in dogs.
    Veterinary medicine, small animal clinician : VM, SAC, 1972, Volume: 67, Issue:4

    Topics: Animals; Dimethyl Sulfoxide; Dog Diseases; Dogs; Snake Bites

1972
Superficial flexor tendon injuries in the greyhound.
    The Veterinary record, 1971, Oct-16, Volume: 89, Issue:16

    Topics: Adrenal Cortex Hormones; Animals; Cautery; Dimethyl Sulfoxide; Dog Diseases; Dogs; Methods; Rupture;

1971
Clinical experience with DMSO in small animal practice.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Animal Diseases; Animals; Animals, Domestic; Cats; Dimethyl Sulfoxide; Dog Diseases; Dogs; Edema; In

1967