dimethyl sulfoxide has been researched along with Cancer of Prostate in 24 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, these therapeutic approaches are considered palliative at this stage, and their significant side effects can cause further decline in patients' quality of life and increase non-cancer-related morbidity/mortality." | 5.37 | Dimethyl sulfoxide-sodium bicarbonate infusion for palliative care and pain relief in patients with metastatic prostate cancer. ( Bui, NT; Ha, TV; Hoang, BX; Hoang, C; Le, BT; Pham, CQ; Pham, TD; Shaw, DG; Tran, DM; Tran, HD; Tran, HQ, 2011) |
| "The use of 40% DMSO with lidocaine instilled into the rectal vault for 10 minutes avoids any need for injection and is capable of decreasing the discomfort or pain experienced during probe insertion and prostate biopsy comparable to the perianal and periprostatic protocols." | 5.11 | Comparison of different local anesthesia techniques during TRUS-guided biopsies: a prospective pilot study. ( Ben-Dor, D; Cytron, S; Dorfman, D; Kesari, D; Kravchick, S; Peled, R, 2005) |
| "A major challenge in the management of prostate cancer (PC) is to limit tumor growth and metastases." | 1.48 | Methylsulfonylmethane (organic sulfur) induces apoptosis and decreases invasiveness of prostate cancer cells. ( Domińska, K; Habrowska-Górczyńska, DE; Kowalska, K; Piastowska-Ciesielska, AW; Urbanek, KA, 2018) |
| "However, these therapeutic approaches are considered palliative at this stage, and their significant side effects can cause further decline in patients' quality of life and increase non-cancer-related morbidity/mortality." | 1.37 | Dimethyl sulfoxide-sodium bicarbonate infusion for palliative care and pain relief in patients with metastatic prostate cancer. ( Bui, NT; Ha, TV; Hoang, BX; Hoang, C; Le, BT; Pham, CQ; Pham, TD; Shaw, DG; Tran, DM; Tran, HD; Tran, HQ, 2011) |
| "Human leukaemic HL-60 and prostate cancer LNCaP and JCA-1 cells were treated with Onc in the absence and presence of several inducers of differentiation and frequency of apoptosis was assessed using three different cytometric methods and confirmed by analysis of cell morphology." | 1.31 | Induction of differentiation of leukaemic (HL-60) or prostate cancer (LNCaP, JCA-1) cells potentiates apoptosis triggered by onconase. ( Darzynkiewicz, Z; Halicka, HD; Mikulski, SM; Mittelman, A; Murakami, T; Papageorgio, CN; Shogen, K, 2000) |
| "We hypothesize that estrogens initiate prostate cancer mainly by formation of 4-catechol estrogens (CE), followed by their oxidation to catechol estrogen-3,4-quinones (CE-3,4-Q), which can react with DNA." | 1.31 | Catechol estrogen metabolites and conjugates in different regions of the prostate of Noble rats treated with 4-hydroxyestradiol: implications for estrogen-induced initiation of prostate cancer. ( Badawi, AF; Bosland, MC; Cavalieri, EL; Devanesan, P; Rogan, EG, 2002) |
| " These data suggest that differentiation agents may provide additional antineoplastic benefits when administered in combination with selected chemotherapeutic agents in the management of prostatic cancer." | 1.28 | Conventional chemotherapeutic agents combined with DMSO or DFMO in treatment of rat prostate carcinoma. ( Carvalho, L; Foulkes, K; Mickey, DD, 1989) |
| "Taxol had a marked cytotoxic effect on prostatic cancer cells down to a 10 nM concentration of taxol when observed by light microscopy." | 1.27 | Morphological studies on the effect of taxol on cultured human prostatic cancer cells. ( Härkönen, P; Laine, KM; Röyttä, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (29.17) | 18.7374 |
| 1990's | 6 (25.00) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kowalska, K | 1 |
| Habrowska-Górczyńska, DE | 1 |
| Domińska, K | 1 |
| Urbanek, KA | 1 |
| Piastowska-Ciesielska, AW | 1 |
| Jiang, C | 1 |
| Qin, Z | 1 |
| Bischof, J | 1 |
| da Silva, AR | 1 |
| Inada, NM | 1 |
| Rettori, D | 1 |
| Baratti, MO | 1 |
| Vercesi, AE | 1 |
| Jorge, RA | 1 |
| Hoang, BX | 1 |
| Le, BT | 1 |
| Tran, HD | 1 |
| Hoang, C | 1 |
| Tran, HQ | 1 |
| Tran, DM | 1 |
| Pham, CQ | 1 |
| Pham, TD | 1 |
| Ha, TV | 1 |
| Bui, NT | 1 |
| Shaw, DG | 1 |
| Zhang, F | 1 |
| Koh, GY | 1 |
| Hollingsworth, J | 1 |
| Russo, PS | 1 |
| Stout, RW | 1 |
| Liu, Z | 1 |
| Schwarzer, R | 1 |
| Tondera, D | 1 |
| Arnold, W | 1 |
| Giese, K | 1 |
| Klippel, A | 1 |
| Kaufmann, J | 1 |
| Kravchick, S | 1 |
| Peled, R | 1 |
| Ben-Dor, D | 1 |
| Dorfman, D | 1 |
| Kesari, D | 1 |
| Cytron, S | 1 |
| Scorey, N | 1 |
| Fraser, SP | 1 |
| Patel, P | 1 |
| Pridgeon, C | 1 |
| Dallman, MJ | 1 |
| Djamgoz, MB | 1 |
| Manna, A | 1 |
| Talevi, N | 1 |
| Manna, M | 1 |
| Porcellini, A | 1 |
| Lucarelli, G | 1 |
| Zhu, W | 1 |
| Murtha, PE | 1 |
| Young, CY | 1 |
| Planchon, SM | 1 |
| Wuerzberger, S | 1 |
| Frydman, B | 1 |
| Witiak, DT | 1 |
| Hutson, P | 1 |
| Church, DR | 1 |
| Wilding, G | 1 |
| Boothman, DA | 1 |
| Arcadi, JA | 1 |
| Narayan, KS | 1 |
| Techy, G | 1 |
| Ng, CP | 1 |
| Saroufeem, RM | 1 |
| Jones, LW | 1 |
| Zolfaghari, A | 1 |
| Djakiew, D | 1 |
| Jana, NR | 1 |
| Sarkar, S | 1 |
| Ishizuka, M | 1 |
| Yonemoto, J | 1 |
| Tohyama, C | 1 |
| Sone, H | 1 |
| Halicka, HD | 1 |
| Murakami, T | 1 |
| Papageorgio, CN | 1 |
| Mittelman, A | 1 |
| Mikulski, SM | 1 |
| Shogen, K | 1 |
| Darzynkiewicz, Z | 1 |
| Jung, M | 1 |
| Muche, JM | 1 |
| Lukowsky, A | 1 |
| Jung, K | 1 |
| Loening, SA | 1 |
| Cavalieri, EL | 1 |
| Devanesan, P | 1 |
| Bosland, MC | 1 |
| Badawi, AF | 1 |
| Rogan, EG | 1 |
| Kaneski, CR | 1 |
| Constantopoulos, G | 1 |
| Brady, RO | 1 |
| Carvalho, L | 2 |
| Foulkes, K | 2 |
| Mickey, DD | 4 |
| Röyttä, M | 1 |
| Laine, KM | 1 |
| Härkönen, P | 1 |
| Hall, M | 2 |
| Silverman, L | 2 |
| Wenger, AS | 2 |
| Mickey, GH | 1 |
| Fried, FA | 1 |
| Chen, TT | 1 |
| Heidelberger, C | 1 |
1 trial available for dimethyl sulfoxide and Cancer of Prostate
| Article | Year |
|---|---|
Comparison of different local anesthesia techniques during TRUS-guided biopsies: a prospective pilot study.
Topics: Adenocarcinoma; Adjuvants, Anesthesia; Administration, Rectal; Aged; Anesthesia, Local; Anesthetics, | 2005 |
23 other studies available for dimethyl sulfoxide and Cancer of Prostate
| Article | Year |
|---|---|
Methylsulfonylmethane (organic sulfur) induces apoptosis and decreases invasiveness of prostate cancer cells.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movem | 2018 |
Membrane-targeting approaches for enhanced cancer cell destruction with irreversible electroporation.
Topics: Cell Line, Tumor; Cell Membrane; Cryoprotective Agents; Dimethyl Sulfoxide; Electrochemotherapy; Hum | 2014 |
In vitro photodynamic activity of chloro(5,10,15,20-tetraphenylporphyrinato)indium(III) loaded-poly(lactide-co-glycolide) nanoparticles in LNCaP prostate tumour cells.
Topics: Animals; Cell Death; Cell Line, Tumor; Cell Survival; Dimethyl Sulfoxide; Dose-Response Relationship | 2009 |
Dimethyl sulfoxide-sodium bicarbonate infusion for palliative care and pain relief in patients with metastatic prostate cancer.
Topics: Adenocarcinoma; Aged; Dimethyl Sulfoxide; Drug Combinations; Humans; Male; Middle Aged; Neoplasm Met | 2011 |
Reformulation of etoposide with solubility-enhancing rubusoside.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Dimethyl S | 2012 |
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.
Topics: Apoptosis; Cell Hypoxia; Cell Line, Tumor; Chromones; Cobalt; Dimethyl Sulfoxide; Gene Expression; H | 2005 |
Notch signalling and voltage-gated Na+ channel activity in human prostate cancer cells: independent modulation of in vitro motility.
Topics: Amyloid Precursor Protein Secretases; Basic Helix-Loop-Helix Transcription Factors; Calcium-Binding | 2006 |
[The use of autologous bone marrow transplants in malignant hemopathies and solid tumors].
Topics: Bone Marrow Transplantation; Carcinoma; Colony-Forming Units Assay; Dimethyl Sulfoxide; Freezing; Hu | 1981 |
Calpain inhibitor-induced apoptosis in human prostate adenocarcinoma cells.
Topics: Adenocarcinoma; Apoptosis; Calpain; Cell Line; Cysteine Proteinase Inhibitors; Diazomethane; Dimethy | 1995 |
Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response.
Topics: Apoptosis; Breast Neoplasms; Camptothecin; Cell Division; Dimethyl Sulfoxide; Drug Screening Assays, | 1995 |
Studies of rhodamine-123: effect on rat prostate cancer and human prostate cancer cells in vitro.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Survival; Dimethyl Sul | 1995 |
Inhibition of chemomigration of a human prostatic carcinoma cell (TSU-pr1) line by inhibition of epidermal growth factor receptor function.
Topics: Alkaloids; Antibodies, Monoclonal; Carbazoles; Carcinogens; Carcinoma; Cell Movement; Dimethyl Sulfo | 1996 |
Cross-talk between 2,3,7,8-tetrachlorodibenzo-p-dioxin and testosterone signal transduction pathways in LNCaP prostate cancer cells.
Topics: Aryl Hydrocarbon Receptor Nuclear Translocator; Cell Division; Cytochrome P-450 CYP1A1; Dimethyl Sul | 1999 |
Induction of differentiation of leukaemic (HL-60) or prostate cancer (LNCaP, JCA-1) cells potentiates apoptosis triggered by onconase.
Topics: Antineoplastic Agents; Apoptosis; Butyrates; Cell Differentiation; Dimethyl Sulfoxide; DNA; Drug Syn | 2000 |
Dimethyl sulfoxide as additive in ready-to-use reaction mixtures for real-time polymerase chain reaction analysis with SYBR Green I dye.
Topics: Benzothiazoles; Diamines; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Fluorescent Dyes; Hu | 2001 |
Catechol estrogen metabolites and conjugates in different regions of the prostate of Noble rats treated with 4-hydroxyestradiol: implications for estrogen-induced initiation of prostate cancer.
Topics: Animals; Caprylates; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dimethyl Su | 2002 |
Effect of dimethylsulfoxide on the proliferation and glycosaminoglycan synthesis of rat prostate adenocarcinoma cells (PAIII) in vitro: isolation and characterization of DMSO-resistant cells.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Dimethyl Sulfoxide; Drug Resistance; | 1991 |
Effect of DMSO and DFMO on rat prostate tumor growth.
Topics: Adenocarcinoma; Animals; Dimethyl Sulfoxide; Disease Models, Animal; Eflornithine; Male; Neoplasm Tr | 1989 |
Conventional chemotherapeutic agents combined with DMSO or DFMO in treatment of rat prostate carcinoma.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophos | 1989 |
Morphological studies on the effect of taxol on cultured human prostatic cancer cells.
Topics: Adenocarcinoma; Alkaloids; Dimethyl Sulfoxide; Humans; Male; Microscopy, Electron; Paclitaxel; Prost | 1987 |
Oncodevelopmental enzymes of the Dunning rat prostatic adenocarcinoma.
Topics: Adenocarcinoma; Adenylate Kinase; Animals; Castration; Cell Differentiation; Cell Line; Creatine Kin | 1985 |
Dimethylsulfoxide-induced changes in a rat prostate adenocarcinoma.
Topics: Adenocarcinoma; Animals; Cell Differentiation; Cell Line; Cells, Cultured; Creatine Kinase; Dimethyl | 1985 |
In vitro malignant transformation of cells derid from mouse prostate in the presence of 3-methylcholanthrene.
Topics: Animals; Cattle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chromosomes; Cricetinae; | 1969 |