dimethyl sulfoxide has been researched along with Brain Swelling in 26 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of a prospective study on the effects of dimethyl sulfoxide (DMSO) in patients with severe closed head injuries causing brain edema and increase in intracranial pressure (ICP) are presented." | 7.68 | Dimethyl sulfoxide in the management of patient with brain swelling and increased intracranial pressure after severe closed head injury. ( Akar, M; Baykut, L; Kulah, A, 1990) |
| "Albino rabbits with experimental brain edema produced by a combined cryogenic left hemisphere lesion and metabolic 6-aminonicotinamide lesion were administered a 3-hour intravenous infusion of dimethyl sulfoxide (DMSO)." | 7.66 | Acute dimethyl sulfoxide therapy in brain edema. Part 3: effect of a 3-hour infusion. ( Camp, PE; Del Bigio, M; James, HE; Marshall, LF; Tung, H; Werner, R, 1982) |
| "Albino rabbits with experimental brain edema produced by a combined cryogenic and metabolic 6-aminonicotinamide lesion were administered intravenous dimethyl sulfoxide in varying concentrations and doses in the following manner: Subgroup A (concentration response) received a 1." | 7.66 | Acute dimethyl sulfoxide therapy in experimental brain edema: part 2. Effect of dose and concentration on intracranial pressure, blood pressure, and central venous pressure. ( Camp, PE; James, HE; Tsuruda, J; Werner, R, 1982) |
| "Albino rabbits with experimental brain edema produced by a cryogenic lesion or by a cryogenic lesion combined with a metabolic blocker, 6-aminonicotinamide, were given 1 g of a 10% solution of dimethyl sulfoxide (DMSO) per kg by intravenous bolus." | 7.66 | Acute dimethyl sulfoxide therapy in experimental brain edema: Part I. Effects on intracranial pressure, blood pressure, central venous pressure, and brain water and electrolyte content. ( Camp, PE; James, HE; Werner, R, 1981) |
| "The safety and tolerability of a free radical scavenger with Na+ channel blocking activity (dimethyl sulfoxide (DMSO)) combined with a glycolytic intermediate and high energy substrate (fructose 1,6-disphosphate (FDP)) were assessed in a mostly elderly patient group presenting with acute and subacute ischemic stroke." | 5.10 | Ischemic stroke in elderly patients treated with a free radical scavenger-glycolytic intermediate solution: a preliminary pilot trial. ( de la Torre, JC; Demir, S; Karaça, M; Kiliç, E; Yazici, B, 2002) |
| "The results of a prospective study on the effects of dimethyl sulfoxide (DMSO) in patients with severe closed head injuries causing brain edema and increase in intracranial pressure (ICP) are presented." | 3.68 | Dimethyl sulfoxide in the management of patient with brain swelling and increased intracranial pressure after severe closed head injury. ( Akar, M; Baykut, L; Kulah, A, 1990) |
| "To ascertain the clinical significance of dimethyl sulfoxide-induced pigmenturia, we evaluated renal function and indicators of systemic hemolysis in stable quadriplegic patients receiving the drug intravenously (IV) for spinal cord injury." | 3.66 | Effects of dimethyl sulfoxide on renal function in man. ( Bennett, WM; Muther, RS, 1980) |
| "Albino rabbits with experimental brain edema produced by a combined cryogenic left hemisphere lesion and metabolic 6-aminonicotinamide lesion were administered a 3-hour intravenous infusion of dimethyl sulfoxide (DMSO)." | 3.66 | Acute dimethyl sulfoxide therapy in brain edema. Part 3: effect of a 3-hour infusion. ( Camp, PE; Del Bigio, M; James, HE; Marshall, LF; Tung, H; Werner, R, 1982) |
| "Albino rabbits with experimental brain edema produced by a combined cryogenic and metabolic 6-aminonicotinamide lesion were administered intravenous dimethyl sulfoxide in varying concentrations and doses in the following manner: Subgroup A (concentration response) received a 1." | 3.66 | Acute dimethyl sulfoxide therapy in experimental brain edema: part 2. Effect of dose and concentration on intracranial pressure, blood pressure, and central venous pressure. ( Camp, PE; James, HE; Tsuruda, J; Werner, R, 1982) |
| "Albino rabbits with experimental brain edema produced by a cryogenic lesion or by a cryogenic lesion combined with a metabolic blocker, 6-aminonicotinamide, were given 1 g of a 10% solution of dimethyl sulfoxide (DMSO) per kg by intravenous bolus." | 3.66 | Acute dimethyl sulfoxide therapy in experimental brain edema: Part I. Effects on intracranial pressure, blood pressure, central venous pressure, and brain water and electrolyte content. ( Camp, PE; James, HE; Werner, R, 1981) |
| "Onyx embolization of cerebral arteriovenous malformations (AVM) has become increasingly common." | 1.37 | Seizures after Onyx embolization for the treatment of cerebral arteriovenous malformation. ( Bederson, JB; de Los Reyes, K; Doshi, A; Egorova, N; Frontera, JA; Panov, F; Patel, A, 2011) |
| "The toxic effects of onyx, its solvent dimethyl sulphoxide (DMSO), and n-butyl 2-cyanoacrylate (NBCA) were evaluated after infusion into the subaracnoid space of a rabbit model." | 1.36 | Evaluation of the toxicity of onyx compared with n-butyl 2-cyanoacrylate in the subarachnoid space of a rabbit model: an experimental research. ( Atilla, P; Bakar, B; Hazer, BD; Kilic, K; Muftuoglu, SF; Oruckaptan, HH; Saatci, I, 2010) |
| "Taurine release was most affected, exhibiting a greater than 9-fold increase during the hyposmotic stimulus." | 1.30 | Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases. ( Estevez, AY; O'Regan, MH; Phillis, JW; Song, D, 1999) |
| "With indomethacin there was an initial decrease immediately following the drug, and at 60 minutes there was a rise in the insulted left hemisphere, more than the right one." | 1.27 | An experimental study on the effects of DMSO and indomethacin on cerebral circulation and intracranial pressure. ( Drummond, JC; James, HE; Moore, S; Tung, H, 1986) |
| "Thus, ischemic cerebral edema appears to contribute heavily to morbidity and mortality in stroke." | 1.26 | Cerebral edema in stroke: a common, often fatal complication. ( Easton, JD; Sherman, DG, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (42.31) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Mirabet, V | 1 |
| García, D | 1 |
| Roca, A | 1 |
| Quiroz, AR | 1 |
| Antón, J | 1 |
| Rodríguez-Cadarso, M | 1 |
| Ocete, D | 1 |
| Aranda, L | 1 |
| Melero, A | 1 |
| Guillot, AJ | 1 |
| Yagüe, N | 1 |
| Guillén, I | 1 |
| Botella, C | 1 |
| Trivelato, FP | 1 |
| Manzato, LB | 1 |
| Rezende, MT | 1 |
| Ulhôa, AC | 1 |
| Soltani, Z | 1 |
| Khaksari, M | 1 |
| Jafari, E | 1 |
| Iranpour, M | 1 |
| Shahrokhi, N | 1 |
| Rossitti, S | 1 |
| Bakar, B | 1 |
| Oruckaptan, HH | 1 |
| Hazer, BD | 1 |
| Saatci, I | 1 |
| Atilla, P | 1 |
| Kilic, K | 1 |
| Muftuoglu, SF | 1 |
| de Los Reyes, K | 1 |
| Patel, A | 1 |
| Doshi, A | 1 |
| Egorova, N | 1 |
| Panov, F | 1 |
| Bederson, JB | 1 |
| Frontera, JA | 1 |
| Ginsberg, MD | 1 |
| Becker, DA | 1 |
| Busto, R | 1 |
| Belayev, A | 1 |
| Zhang, Y | 1 |
| Khoutorova, L | 1 |
| Ley, JJ | 1 |
| Zhao, W | 1 |
| Belayev, L | 1 |
| Kleindienst, A | 1 |
| Dunbar, JG | 1 |
| Glisson, R | 1 |
| Okuno, K | 1 |
| Marmarou, A | 1 |
| Goodnough, J | 1 |
| Allen, N | 1 |
| Nesham, ME | 1 |
| Clendenon, NR | 1 |
| James, HE | 7 |
| Cornell, W | 1 |
| del Bigio, M | 2 |
| Werner, R | 6 |
| Tsuruda, J | 2 |
| Camp, PE | 5 |
| Rasmussen, G | 1 |
| Sherman, DG | 1 |
| Easton, JD | 1 |
| Chan, PH | 1 |
| Yurko, M | 1 |
| Fishman, RA | 1 |
| Muther, RS | 1 |
| Bennett, WM | 1 |
| Marshall, LF | 2 |
| Tung, H | 2 |
| Harbaugh, RD | 1 |
| McConnel, JR | 1 |
| Ong, CS | 1 |
| McAllister, JL | 1 |
| Gross, TG | 1 |
| Banks, P | 1 |
| Roussel, AJ | 1 |
| Mealey, RH | 1 |
| Estevez, AY | 1 |
| O'Regan, MH | 1 |
| Song, D | 1 |
| Phillis, JW | 1 |
| Kumon, Y | 1 |
| Kim, SC | 1 |
| Tompkins, P | 1 |
| Stevens, A | 1 |
| Sakaki, S | 1 |
| Loftus, CM | 1 |
| Karaça, M | 1 |
| Kiliç, E | 1 |
| Yazici, B | 1 |
| Demir, S | 1 |
| de la Torre, JC | 1 |
| Ikeda, Y | 1 |
| Long, DM | 1 |
| Kulah, A | 1 |
| Akar, M | 1 |
| Baykut, L | 1 |
| Drummond, JC | 1 |
| Moore, S | 1 |
1 trial available for dimethyl sulfoxide and Brain Swelling
| Article | Year |
|---|---|
Ischemic stroke in elderly patients treated with a free radical scavenger-glycolytic intermediate solution: a preliminary pilot trial.
Topics: Adult; Aged; Aging; Brain; Brain Edema; Cerebrovascular Circulation; Dimethyl Sulfoxide; Drug Combin | 2002 |
25 other studies available for dimethyl sulfoxide and Brain Swelling
| Article | Year |
|---|---|
Cranioplasty with Autologous Bone Flaps Cryopreserved with Dimethylsulphoxide: Does Tissue Processing Matter.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Autografts; Bone Resorption; Brain Edema; Brain Injuries, | 2021 |
Transitory brain stem edema following successfully transvenous embolization of a posterior fossa arteriovenous malformation.
Topics: Brain Edema; Dimethyl Sulfoxide; Embolization, Therapeutic; Humans; Intracranial Arteriovenous Malfo | 2014 |
Is genistein neuroprotective in traumatic brain injury?
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Capillary Permeability; Dimethyl S | 2015 |
Transarterial embolization of intracranial dural arteriovenous fistulas with direct cortical venous drainage using ethylene vinyl alcohol copolymer (Onyx).
Topics: Aged; Brain Edema; Central Nervous System Vascular Malformations; Cerebral Angiography; Cerebral Art | 2009 |
Evaluation of the toxicity of onyx compared with n-butyl 2-cyanoacrylate in the subarachnoid space of a rabbit model: an experimental research.
Topics: Animals; Brain; Brain Edema; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enbucrilate; Lipi | 2010 |
Seizures after Onyx embolization for the treatment of cerebral arteriovenous malformation.
Topics: Adult; Brain Edema; Dimethyl Sulfoxide; Embolization, Therapeutic; Epilepsy; Female; Humans; Intracr | 2011 |
Stilbazulenyl nitrone, a novel antioxidant, is highly neuroprotective in focal ischemia.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Brain Edema; Dimethyl Sulfoxide; Disease Models, Ani | 2003 |
Effect of dimethyl sulfoxide on blood-brain barrier integrity following middle cerebral artery occlusion in the rat.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Inf | 2006 |
The effect of dimethyl sulfoxide on gray matter injury in experimental spinal cord trauma.
Topics: Animals; Brain Edema; Culture Techniques; Dimethyl Sulfoxide; Dogs; Electron Transport Complex IV; F | 1980 |
Dimethyl sulfoxide in brain edema and intracranial pressure.
Topics: Animals; Blood Pressure; Brain Edema; Dimethyl Sulfoxide; Intracranial Pressure; Pentobarbital; Rabb | 1983 |
Acute dimethyl sulphoxide therapy in experimental brain oedema, effect of dose and concentration on brain water and electrolyte content.
Topics: Animals; Body Water; Brain; Brain Edema; Dimethyl Sulfoxide; Potassium; Rabbits; Sodium | 1983 |
Cerebral edema in stroke: a common, often fatal complication.
Topics: Adrenal Cortex Hormones; Antioxidants; Barbiturates; Brain Edema; Cerebral Infarction; Cerebrovascul | 1980 |
Phospholipid degradation and cellular edema induced by free radicals in brain cortical slices.
Topics: Animals; Brain Edema; Cerebral Cortex; Dimethyl Sulfoxide; Free Radicals; Lactates; Lactic Acid; Lip | 1982 |
Effects of dimethyl sulfoxide on renal function in man.
Topics: Adolescent; Adult; Brain Edema; Dimethyl Sulfoxide; Female; Hemoglobinuria; Hemolysis; Humans; Kidne | 1980 |
Acute dimethyl sulfoxide therapy in brain edema. Part 3: effect of a 3-hour infusion.
Topics: Animals; Blood Pressure; Body Water; Brain Chemistry; Brain Edema; Dimethyl Sulfoxide; Female; Intra | 1982 |
Acute dimethyl sulfoxide therapy in experimental brain edema: part 2. Effect of dose and concentration on intracranial pressure, blood pressure, and central venous pressure.
Topics: 6-Aminonicotinamide; Animals; Blood Pressure; Brain Edema; Central Venous Pressure; Dimethyl Sulfoxi | 1982 |
Comparison of the effects of DMSO and pentobarbitone on experimental brain oedema.
Topics: Animals; Blood Pressure; Brain Chemistry; Brain Edema; Central Venous Pressure; Dimethyl Sulfoxide; | 1982 |
Acute dimethyl sulfoxide therapy in experimental brain edema: Part I. Effects on intracranial pressure, blood pressure, central venous pressure, and brain water and electrolyte content.
Topics: Animals; Blood Pressure; Body Water; Brain Chemistry; Brain Edema; Central Venous Pressure; Dimethyl | 1981 |
Propylene glycol toxicity following continuous etomidate infusion for the control of refractory cerebral edema.
Topics: Acidosis, Lactic; Brain; Brain Edema; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug The | 1996 |
High-sodium crystalloid solution for treatment of hypernatremia in a Vietnamese pot-bellied pig.
Topics: Animals; Anti-Inflammatory Agents; Brain Edema; Dehydration; Dexamethasone; Dimethyl Sulfoxide; Drug | 1996 |
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebra | 1999 |
Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia.
Topics: Analysis of Variance; Animals; Brain Edema; Cerebrovascular Circulation; Dimethyl Sulfoxide; Follow- | 2000 |
Comparative effects of direct and indirect hydroxyl radical scavengers on traumatic brain oedema.
Topics: Animals; Body Water; Brain; Brain Edema; Brain Injuries; Cats; Deferoxamine; Dimethyl Sulfoxide; Fre | 1990 |
Dimethyl sulfoxide in the management of patient with brain swelling and increased intracranial pressure after severe closed head injury.
Topics: Adolescent; Adult; Brain Concussion; Brain Edema; Child; Dimethyl Sulfoxide; Female; Glasgow Coma Sc | 1990 |
An experimental study on the effects of DMSO and indomethacin on cerebral circulation and intracranial pressure.
Topics: Animals; Brain Edema; Cerebrovascular Circulation; Dimethyl Sulfoxide; Indomethacin; Intracranial Pr | 1986 |