Page last updated: 2024-10-18

dimethyl sulfoxide and Brain Neoplasms

dimethyl sulfoxide has been researched along with Brain Neoplasms in 23 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
"The role of N-myc, c-src, and major histocompatibility complex (MHC, H-2 in the mouse) class I antigen gene expressions in dimethyl sulfoxide (DMSO)-induced differentiation and intracerebral tumorigenicity was examined using a mouse MNB85 neuroblastoma cell line."3.68Role of histocompatibility antigen gene and protooncogene expressions in intracerebral tumorigenicity of mouse neuroblastoma. ( Kärre, K; Kikuchi, H; Klein, G; Ljunggren, HG; Moritake, K; Paine, JT; Yamasaki, T, 1993)
"Juvenile angiofibromas are hypervascular tumors that may benefit from preoperative devascularization to reduce intraoperative blood loss."2.77Preliminary experience with the percutaneous embolization of juvenile angiofibromas using only ethylene-vinyl alcohol copolymer (Onyx) for preoperative devascularization prior to surgical resection. ( Chaudhary, N; Gemmete, JJ; Marentette, LJ; McKean, EL; Pandey, AS; Patel, S; Sullivan, SE, 2012)
"The resection of glomus jugulare tumors can be challenging because of their inherent vascularity."1.40Incidence of cranial nerve palsy after preoperative embolization of glomus jugulare tumors using Onyx. ( Angeli, SI; Aziz-Sultan, MA; Elhammady, MS; Gaynor, BG; Jethanamest, D, 2014)
"Intracranial hemangiopericytomas are uncommon but highly vascular dural-based tumors which commonly derive arterial blood supply from both intracranial and extracranial circulations."1.39Onyx embolization of an intracranial hemangiopericytoma by direct transcranial puncture. ( Ding, D; Kreitel, D; Liu, KC, 2013)
"A total of nine pseudoaneurysms treated by Onyx embolization were identified."1.39Onyx embolization for the endovascular treatment of infectious and traumatic aneurysms involving the cranial and cerebral vasculature. ( Jadhav, AP; Nogueira, RG; Pryor, JC, 2013)
"Pretreatment with pyrrolidine dithiocarbamate (PDTC), an inhibitor of the redox sensitive transcription factor NF-kappa B, abrogated the increased expression of p53 protein in response to H(2)O(2), and enhanced cell survival."1.31p53 dependent apoptosis in glioma cell lines in response to hydrogen peroxide induced oxidative stress. ( Babbar, P; Chattopadhyay, P; Datta, K; Sinha, S; Srivastava, T, 2002)
" The highest bioavailability was obtained with busulphan in DMSO administered i."1.30Busulphan is active against neuroblastoma and medulloblastoma xenografts in athymic mice at clinically achievable plasma drug concentrations. ( Boland, I; Gouyette, A; Hartmann, O; Kalifa, C; Morizet, J; Terrier-Lacombe, MJ; Valteau-Couanet, D; Vassal, G, 1999)
"Glioblastoma multiforme is composed of multiple cellular compartments with different morphologic, kinetic, metabolic, vascular, and genetic properties."1.26Aggressive multimodality therapy based on a multicompartmental model of glioblastoma. ( Broadwell, RD; Ducker, TB; Kaplan, RS; Salcman, M; Samaras, GM, 1982)
"Ten patients with brain tumors and indwelling ventricular reservoirs were pretreated with 5% to 10% dimethyl sulfoxide (DMSO) (intravenous, oral, or both) and were then treated with 1."1.26Cyclophosphamide plasma and cerebrospinal fluid kinetics with and without dimethyl sulfoxide. ( Aisner, J; Bachur, NR; Colvin, M; Egorin, MJ; Kaplan, RS; Salcman, M; Wiernik, PH, 1982)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19906 (26.09)18.7374
1990's3 (13.04)18.2507
2000's5 (21.74)29.6817
2010's7 (30.43)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Przybylowski, CJ1
Zhao, X1
Baranoski, JF1
Borba Moreira, L1
Gandhi, S1
Chapple, KM1
Almefty, KK1
Sanai, N1
Ducruet, AF1
Albuquerque, FC3
Little, AS1
Nakaji, P2
Day, EK1
Zhong, Q1
Purow, B1
Lazzara, MJ1
Ricci, M1
Ragonese, F1
Gironi, B1
Paolantoni, M1
Morresi, A1
Latterini, L1
Fioretti, B1
Sassi, P1
Gaynor, BG1
Elhammady, MS1
Jethanamest, D1
Angeli, SI1
Aziz-Sultan, MA1
Ding, D1
Kreitel, D1
Liu, KC1
Park, S1
Hwang, SM1
Lim, OK1
Hwang, C1
Lee, DH1
Gore, P1
Theodore, N1
Brasiliense, L1
Kim, LJ1
Garrett, M1
Gonzalez, LF1
McDougall, CG2
Dashti, SR1
Fiorella, D1
Spetzler, RF1
Beres, E1
Gemmete, JJ1
Patel, S1
Pandey, AS1
Sullivan, SE1
McKean, EL1
Marentette, LJ1
Chaudhary, N1
Delgado-Goñi, T1
Martín-Sitjar, J1
Simões, RV1
Acosta, M1
Lope-Piedrafita, S1
Arús, C1
Jadhav, AP1
Pryor, JC1
Nogueira, RG1
Jeong, YI1
Kim, SH1
Jung, TY1
Kim, IY1
Kang, SS1
Jin, YH1
Ryu, HH1
Sun, HS1
Jin, S1
Kim, KK1
Ahn, KY1
Jung, S1
Salcman, M3
Kaplan, RS3
Ducker, TB2
Abdo, H1
Montgomery, E1
Samaras, GM1
Broadwell, RD1
Neuwelt, EA1
Chudinovskaia, NV1
Poliakova, GP1
Kondakova, LI1
Egorin, MJ1
Aisner, J1
Colvin, M1
Wiernik, PH1
Bachur, NR1
Thomé, S1
Craze, J1
Mitchell, C1
Yamasaki, T1
Klein, G1
Ljunggren, HG1
Kärre, K1
Moritake, K1
Paine, JT1
Kikuchi, H1
Boland, I1
Vassal, G1
Morizet, J1
Terrier-Lacombe, MJ1
Valteau-Couanet, D1
Kalifa, C1
Hartmann, O1
Gouyette, A1
Biçaku, E1
Acevedo-Duncan, M1
Datta, K1
Babbar, P1
Srivastava, T1
Sinha, S1
Chattopadhyay, P1
Greig, NH1
Sweeney, DJ1
Rapoport, SI1

Trials

1 trial available for dimethyl sulfoxide and Brain Neoplasms

ArticleYear
Preliminary experience with the percutaneous embolization of juvenile angiofibromas using only ethylene-vinyl alcohol copolymer (Onyx) for preoperative devascularization prior to surgical resection.
    AJNR. American journal of neuroradiology, 2012, Volume: 33, Issue:9

    Topics: Adolescent; Angiofibroma; Brain Neoplasms; Child; Child, Preschool; Dimethyl Sulfoxide; Embolization

2012

Other Studies

22 other studies available for dimethyl sulfoxide and Brain Neoplasms

ArticleYear
Preoperative embolization versus no embolization for WHO grade I intracranial meningioma: a retrospective matched cohort study.
    Journal of neurosurgery, 2020, 03-27, Volume: 134, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Cohort Studies; Dimethyl Sulfoxide; Embolization, Therapeutic; Female;

2020
Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to SHP2 Inhibition.
    Cancer research, 2021, 04-15, Volume: 81, Issue:8

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Data Science; Dimethyl Sulfoxide; DNA Repair; Drug Resis

2021
Glioblastoma single-cell microRaman analysis under stress treatments.
    Scientific reports, 2018, 05-22, Volume: 8, Issue:1

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dimethyl Sulfoxide; Glioblastoma; Glucose; Humans; Hyd

2018
Incidence of cranial nerve palsy after preoperative embolization of glomus jugulare tumors using Onyx.
    Journal of neurosurgery, 2014, Volume: 120, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Cerebral Angiography; Cerebral Revascularization; Cranial Nerve Diseas

2014
Onyx embolization of an intracranial hemangiopericytoma by direct transcranial puncture.
    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2013, Volume: 19, Issue:4

    Topics: Brain Neoplasms; Cerebral Angiography; Dimethyl Sulfoxide; Embolization, Therapeutic; Female; Hemang

2013
Compliant neurovascular balloon catheters may not be compatible with liquid embolic materials: intraprocedural rupture of the protecting balloon during tumor embolization using n-butyl cyanoacrylate and lipiodol mixture.
    Journal of neurointerventional surgery, 2015, Volume: 7, Issue:10

    Topics: Antineoplastic Agents; Balloon Occlusion; Brain Neoplasms; Catheters; Chemoembolization, Therapeutic

2015
The utility of onyx for preoperative embolization of cranial and spinal tumors.
    Neurosurgery, 2008, Volume: 62, Issue:6

    Topics: Adult; Brain Neoplasms; Child; Cohort Studies; Dimethyl Sulfoxide; Embolization, Therapeutic; Female

2008
Preoperative Onyx embolization of a giant cavernous malformation involving the dural sinuses.
    Journal of neurosurgery. Pediatrics, 2009, Volume: 3, Issue:4

    Topics: Brain Neoplasms; Child; Cranial Sinuses; Dimethyl Sulfoxide; Embolization, Therapeutic; Hemangioma,

2009
Dimethyl sulfoxide (DMSO) as a potential contrast agent for brain tumors.
    NMR in biomedicine, 2013, Volume: 26, Issue:2

    Topics: Animals; Brain Neoplasms; Contrast Media; Dimethyl Sulfoxide; Feasibility Studies; Female; Glioblast

2013
Onyx embolization for the endovascular treatment of infectious and traumatic aneurysms involving the cranial and cerebral vasculature.
    Journal of neurointerventional surgery, 2013, Volume: 5, Issue:6

    Topics: Adult; Aged; Aneurysm, False; Aneurysm, Infected; Anterior Cerebral Artery; Brain Injuries; Brain Ne

2013
Polyion complex micelles composed of all-trans retinoic acid and poly (ethylene glycol)-grafted-chitosan.
    Journal of pharmaceutical sciences, 2006, Volume: 95, Issue:11

    Topics: Adsorption; Antineoplastic Agents; Brain Neoplasms; Carbohydrate Sequence; Cell Line, Tumor; Cell Su

2006
Effect of age and reoperation on survival in the combined modality treatment of malignant astrocytoma.
    Neurosurgery, 1982, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Brain Neoplasms; Carmustine; Dimethyl Sulfoxide; Doxorubicin;

1982
Aggressive multimodality therapy based on a multicompartmental model of glioblastoma.
    Surgery, 1982, Volume: 92, Issue:2

    Topics: Brain Neoplasms; Carmustine; Dimethyl Sulfoxide; Drug Therapy, Combination; Glioblastoma; Hot Temper

1982
Therapeutic potential for blood-brain barrier modification in malignant brain tumor.
    Progress in experimental tumor research, 1984, Volume: 28

    Topics: Adrenal Cortex Hormones; Animals; Blood-Brain Barrier; Brain Neoplasms; Dimethyl Sulfoxide; Dogs; Do

1984
[Cytological study of the fusion of mouse glioblastoma cells with rat neurinoma cell after the administration of polyethylene glycol combined with dimethyl sulfoxide].
    Vestnik Akademii meditsinskikh nauk SSSR, 1984, Issue:1

    Topics: Animals; Autoradiography; Brain Neoplasms; Cells, Cultured; Cranial Nerve Neoplasms; Dimethyl Sulfox

1984
Cyclophosphamide plasma and cerebrospinal fluid kinetics with and without dimethyl sulfoxide.
    Clinical pharmacology and therapeutics, 1982, Volume: 32, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Cyclophosphamide; Dimethyl Sulfoxide; Drug Interactions; Drug Therapy,

1982
Dimethylsulphoxide-induced serum hyperosmolality after cryopreserved stem-cell graft.
    Lancet (London, England), 1994, Nov-19, Volume: 344, Issue:8934

    Topics: Adolescent; Brain Neoplasms; Cryopreservation; Dimethyl Sulfoxide; Germinoma; Hematopoietic Stem Cel

1994
Role of histocompatibility antigen gene and protooncogene expressions in intracerebral tumorigenicity of mouse neuroblastoma.
    Journal of neurosurgery, 1993, Volume: 78, Issue:4

    Topics: Animals; Brain Neoplasms; Dimethyl Sulfoxide; Gene Expression Regulation, Neoplastic; Genes, MHC Cla

1993
Busulphan is active against neuroblastoma and medulloblastoma xenografts in athymic mice at clinically achievable plasma drug concentrations.
    British journal of cancer, 1999, Volume: 79, Issue:5-6

    Topics: Administration, Oral; Animals; Biological Availability; Brain Neoplasms; Busulfan; Carboxymethylcell

1999
Ultrastructural study of protein kinase C-betaII localization during the cell cycle of human glioma cells.
    Tissue & cell, 2001, Volume: 33, Issue:1

    Topics: Blotting, Western; Brain Neoplasms; Cell Cycle; Dimethyl Sulfoxide; Glioma; Humans; Immunohistochemi

2001
p53 dependent apoptosis in glioma cell lines in response to hydrogen peroxide induced oxidative stress.
    The international journal of biochemistry & cell biology, 2002, Volume: 34, Issue:2

    Topics: Antioxidants; Apoptosis; Brain Neoplasms; Cell Survival; Dimethyl Sulfoxide; Flow Cytometry; Glioma;

2002
Inability of dimethyl sulfoxide to increase brain uptake of water-soluble compounds: implications to chemotherapy for brain tumors.
    Cancer treatment reports, 1985, Volume: 69, Issue:3

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Cerebrovascular Circulation; Dimethyl Sulfoxid

1985