dimethyl sulfoxide has been researched along with Brain Injuries in 18 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
Excerpt | Relevance | Reference |
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"Sprague-Dawley (SD) pups were randomly divided into the nonhyperoxia (NN) group, the nonhyperoxia with dimethyl sulfoxide (ND) group, the nonhyperoxia with Res (NR) group, the hyperoxia (HN) group, the hyperoxia with dimethyl sulfoxide (HD) group, and the hyperoxia with Res (HR) group within 12 h after birth." | 8.31 | Protective effect of resveratrol on mitochondrial biogenesis during hyperoxia-induced brain injury in neonatal pups. ( Dong, W; Lei, X; Shen, Y; Yang, M; Zhang, R; Zhao, S, 2023) |
"Sprague-Dawley (SD) pups were randomly divided into the nonhyperoxia (NN) group, the nonhyperoxia with dimethyl sulfoxide (ND) group, the nonhyperoxia with Res (NR) group, the hyperoxia (HN) group, the hyperoxia with dimethyl sulfoxide (HD) group, and the hyperoxia with Res (HR) group within 12 h after birth." | 4.31 | Protective effect of resveratrol on mitochondrial biogenesis during hyperoxia-induced brain injury in neonatal pups. ( Dong, W; Lei, X; Shen, Y; Yang, M; Zhang, R; Zhao, S, 2023) |
"A total of nine pseudoaneurysms treated by Onyx embolization were identified." | 1.39 | Onyx embolization for the endovascular treatment of infectious and traumatic aneurysms involving the cranial and cerebral vasculature. ( Jadhav, AP; Nogueira, RG; Pryor, JC, 2013) |
"Dimethyl sulfoxide (DMSO) has shown promise as a drug for the treatment of intracranial hypertension." | 1.27 | Dimethyl sulfoxide for the treatment of intracranial hypertension: a preliminary trial. ( Bowers, SA; Camp, PE; Marshall, LF, 1984) |
"Dimethyl sulfoxide has been tested in various experimental injuries of the central nervous system in relation to other therapies." | 1.25 | Dimethyl sulfoxide in central nervous system trauma. ( de la Torre, JC; Goode, DJ; Johnson, CM; Kajihara, K; Kawanaga, HM; Mullan, S, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (44.44) | 18.7374 |
1990's | 1 (5.56) | 18.2507 |
2000's | 3 (16.67) | 29.6817 |
2010's | 3 (16.67) | 24.3611 |
2020's | 3 (16.67) | 2.80 |
Authors | Studies |
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Amirshahrokhi, K | 1 |
Niapour, A | 1 |
Fang, Q | 1 |
Zheng, S | 1 |
Chen, Q | 1 |
Chen, L | 1 |
Yang, Y | 1 |
Wang, Y | 1 |
Zhang, H | 1 |
Chen, J | 1 |
Yang, M | 1 |
Shen, Y | 1 |
Zhao, S | 1 |
Zhang, R | 1 |
Dong, W | 1 |
Lei, X | 1 |
Budinich, CS | 1 |
Tucker, LB | 1 |
Lowe, D | 1 |
Rosenberger, JG | 1 |
McCabe, JT | 1 |
Soltani, Z | 1 |
Khaksari, M | 1 |
Jafari, E | 1 |
Iranpour, M | 1 |
Shahrokhi, N | 1 |
Di Giorgio, AM | 1 |
Hou, Y | 1 |
Zhao, X | 1 |
Zhang, B | 1 |
Lyeth, BG | 1 |
Russell, MJ | 1 |
Reig, AS | 1 |
Simon, S | 1 |
Mericle, RA | 1 |
Jadhav, AP | 1 |
Pryor, JC | 1 |
Nogueira, RG | 1 |
Chen-Plotkin, AS | 1 |
Vossel, KA | 1 |
Samuels, MA | 1 |
Chen, MH | 1 |
Marshall, LF | 1 |
Camp, PE | 1 |
Bowers, SA | 1 |
Brown, FD | 3 |
Johns, L | 1 |
Mullan, S | 4 |
Johns, LM | 2 |
Mullan, JF | 1 |
de la Torre, JC | 2 |
Kawanaga, HM | 2 |
Johnson, CM | 1 |
Goode, DJ | 1 |
Kajihara, K | 1 |
Scherbel, AR | 1 |
Ikeda, Y | 1 |
Long, DM | 1 |
Albin, MS | 1 |
Bunegin, L | 1 |
Rowed, DW | 1 |
18 other studies available for dimethyl sulfoxide and Brain Injuries
Article | Year |
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Methylsulfonylmethane protects against ethanol-induced brain injury in mice through the inhibition of oxidative stress, proinflammatory mediators and apoptotic cell death.
Topics: Animals; Antioxidants; Apoptosis; Brain Injuries; Dimethyl Sulfoxide; Ethanol; Humans; Mice; Mice, I | 2022 |
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
Topics: Animals; Brain Injuries; Caspase 3; Dimethyl Sulfoxide; Epilepsy; Hippocampus; Kindling, Neurologic; | 2023 |
Protective effect of resveratrol on mitochondrial biogenesis during hyperoxia-induced brain injury in neonatal pups.
Topics: Brain Injuries; Dimethyl Sulfoxide; Humans; Hyperoxia; NF-E2-Related Factor 2; Organelle Biogenesis; | 2023 |
Short and long-term motor and behavioral effects of diazoxide and dimethyl sulfoxide administration in the mouse after traumatic brain injury.
Topics: Animals; Behavior, Animal; Brain Injuries; Diazoxide; Dimethyl Sulfoxide; Male; Maze Learning; Mice; | 2013 |
Is genistein neuroprotective in traumatic brain injury?
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Capillary Permeability; Dimethyl S | 2015 |
Dimethyl sulfoxide provides neuroprotection in a traumatic brain injury model.
Topics: alpha-Tocopherol; Analysis of Variance; Animals; Brain; Brain Injuries; Dimethyl Sulfoxide; Disease | 2008 |
Embolization of a giant pediatric, posttraumatic, skull base internal carotid artery aneurysm with a liquid embolic agent.
Topics: Anticoagulants; Brain Injuries; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Angiogra | 2009 |
Onyx embolization for the endovascular treatment of infectious and traumatic aneurysms involving the cranial and cerebral vasculature.
Topics: Adult; Aged; Aneurysm, False; Aneurysm, Infected; Anterior Cerebral Artery; Brain Injuries; Brain Ne | 2013 |
Encephalopathy, stroke, and myocardial infarction with DMSO use in stem cell transplantation.
Topics: Brain Injuries; Dimethyl Sulfoxide; Female; Humans; Male; Middle Aged; Myocardial Infarction; Stem C | 2007 |
Dimethyl sulfoxide for the treatment of intracranial hypertension: a preliminary trial.
Topics: Adult; Brain Injuries; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Female; Hematoma, Epidu | 1984 |
Dimethyl sulfoxide therapy following penetrating brain injury.
Topics: Animals; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Dimethyl Sulfoxide; Intracrani | 1983 |
Dimethyl sulfoxide in experimental brain injury, with comparison to mannitol.
Topics: Animals; Brain Injuries; Cerebrovascular Circulation; Dimethyl Sulfoxide; Disease Models, Animal; In | 1980 |
DMSO treatment in an experimental cerebral missile injury.
Topics: Animals; Brain Injuries; Brain Ischemia; Dimethyl Sulfoxide; Haplorhini; Hypotension; Macaca mulatta | 1979 |
Dimethyl sulfoxide in central nervous system trauma.
Topics: Animals; Brain; Brain Injuries; Cerebral Arteries; Craniocerebral Trauma; Dimethyl Sulfoxide; Female | 1975 |
Summary of the dimethyl sulfoxide conference.
Topics: Animals; Antineoplastic Agents; Brain Injuries; Dimethyl Sulfoxide; Humans; Neoplasms, Experimental; | 1975 |
Comparative effects of direct and indirect hydroxyl radical scavengers on traumatic brain oedema.
Topics: Animals; Body Water; Brain; Brain Edema; Brain Injuries; Cats; Deferoxamine; Dimethyl Sulfoxide; Fre | 1990 |
An experimental study of craniocerebral trauma during ethanol intoxication.
Topics: Alcoholic Intoxication; Animals; Blood Pressure; Brain Injuries; Dimethyl Sulfoxide; Dogs; Ischemic | 1986 |
Dimethyl sulfoxide in the treatment of experimental brain compression.
Topics: Animals; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Dimethyl Sulfoxide; Disease Mo | 1973 |