Page last updated: 2024-10-18

dimethyl sulfoxide and Brain Injuries

dimethyl sulfoxide has been researched along with Brain Injuries in 18 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.

Research Excerpts

ExcerptRelevanceReference
"Sprague-Dawley (SD) pups were randomly divided into the nonhyperoxia (NN) group, the nonhyperoxia with dimethyl sulfoxide (ND) group, the nonhyperoxia with Res (NR) group, the hyperoxia (HN) group, the hyperoxia with dimethyl sulfoxide (HD) group, and the hyperoxia with Res (HR) group within 12 h after birth."8.31Protective effect of resveratrol on mitochondrial biogenesis during hyperoxia-induced brain injury in neonatal pups. ( Dong, W; Lei, X; Shen, Y; Yang, M; Zhang, R; Zhao, S, 2023)
"Sprague-Dawley (SD) pups were randomly divided into the nonhyperoxia (NN) group, the nonhyperoxia with dimethyl sulfoxide (ND) group, the nonhyperoxia with Res (NR) group, the hyperoxia (HN) group, the hyperoxia with dimethyl sulfoxide (HD) group, and the hyperoxia with Res (HR) group within 12 h after birth."4.31Protective effect of resveratrol on mitochondrial biogenesis during hyperoxia-induced brain injury in neonatal pups. ( Dong, W; Lei, X; Shen, Y; Yang, M; Zhang, R; Zhao, S, 2023)
"A total of nine pseudoaneurysms treated by Onyx embolization were identified."1.39Onyx embolization for the endovascular treatment of infectious and traumatic aneurysms involving the cranial and cerebral vasculature. ( Jadhav, AP; Nogueira, RG; Pryor, JC, 2013)
"Dimethyl sulfoxide (DMSO) has shown promise as a drug for the treatment of intracranial hypertension."1.27Dimethyl sulfoxide for the treatment of intracranial hypertension: a preliminary trial. ( Bowers, SA; Camp, PE; Marshall, LF, 1984)
"Dimethyl sulfoxide has been tested in various experimental injuries of the central nervous system in relation to other therapies."1.25Dimethyl sulfoxide in central nervous system trauma. ( de la Torre, JC; Goode, DJ; Johnson, CM; Kajihara, K; Kawanaga, HM; Mullan, S, 1975)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19908 (44.44)18.7374
1990's1 (5.56)18.2507
2000's3 (16.67)29.6817
2010's3 (16.67)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Amirshahrokhi, K1
Niapour, A1
Fang, Q1
Zheng, S1
Chen, Q1
Chen, L1
Yang, Y1
Wang, Y1
Zhang, H1
Chen, J1
Yang, M1
Shen, Y1
Zhao, S1
Zhang, R1
Dong, W1
Lei, X1
Budinich, CS1
Tucker, LB1
Lowe, D1
Rosenberger, JG1
McCabe, JT1
Soltani, Z1
Khaksari, M1
Jafari, E1
Iranpour, M1
Shahrokhi, N1
Di Giorgio, AM1
Hou, Y1
Zhao, X1
Zhang, B1
Lyeth, BG1
Russell, MJ1
Reig, AS1
Simon, S1
Mericle, RA1
Jadhav, AP1
Pryor, JC1
Nogueira, RG1
Chen-Plotkin, AS1
Vossel, KA1
Samuels, MA1
Chen, MH1
Marshall, LF1
Camp, PE1
Bowers, SA1
Brown, FD3
Johns, L1
Mullan, S4
Johns, LM2
Mullan, JF1
de la Torre, JC2
Kawanaga, HM2
Johnson, CM1
Goode, DJ1
Kajihara, K1
Scherbel, AR1
Ikeda, Y1
Long, DM1
Albin, MS1
Bunegin, L1
Rowed, DW1

Other Studies

18 other studies available for dimethyl sulfoxide and Brain Injuries

ArticleYear
Methylsulfonylmethane protects against ethanol-induced brain injury in mice through the inhibition of oxidative stress, proinflammatory mediators and apoptotic cell death.
    International immunopharmacology, 2022, Volume: 106

    Topics: Animals; Antioxidants; Apoptosis; Brain Injuries; Dimethyl Sulfoxide; Ethanol; Humans; Mice; Mice, I

2022
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
    Metabolic brain disease, 2023, Volume: 38, Issue:2

    Topics: Animals; Brain Injuries; Caspase 3; Dimethyl Sulfoxide; Epilepsy; Hippocampus; Kindling, Neurologic;

2023
Protective effect of resveratrol on mitochondrial biogenesis during hyperoxia-induced brain injury in neonatal pups.
    BMC neuroscience, 2023, 04-25, Volume: 24, Issue:1

    Topics: Brain Injuries; Dimethyl Sulfoxide; Humans; Hyperoxia; NF-E2-Related Factor 2; Organelle Biogenesis;

2023
Short and long-term motor and behavioral effects of diazoxide and dimethyl sulfoxide administration in the mouse after traumatic brain injury.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 108

    Topics: Animals; Behavior, Animal; Brain Injuries; Diazoxide; Dimethyl Sulfoxide; Male; Maze Learning; Mice;

2013
Is genistein neuroprotective in traumatic brain injury?
    Physiology & behavior, 2015, Dec-01, Volume: 152, Issue:Pt A

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Capillary Permeability; Dimethyl S

2015
Dimethyl sulfoxide provides neuroprotection in a traumatic brain injury model.
    Restorative neurology and neuroscience, 2008, Volume: 26, Issue:6

    Topics: alpha-Tocopherol; Analysis of Variance; Animals; Brain; Brain Injuries; Dimethyl Sulfoxide; Disease

2008
Embolization of a giant pediatric, posttraumatic, skull base internal carotid artery aneurysm with a liquid embolic agent.
    Journal of neurosurgery. Pediatrics, 2009, Volume: 4, Issue:5

    Topics: Anticoagulants; Brain Injuries; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Angiogra

2009
Onyx embolization for the endovascular treatment of infectious and traumatic aneurysms involving the cranial and cerebral vasculature.
    Journal of neurointerventional surgery, 2013, Volume: 5, Issue:6

    Topics: Adult; Aged; Aneurysm, False; Aneurysm, Infected; Anterior Cerebral Artery; Brain Injuries; Brain Ne

2013
Encephalopathy, stroke, and myocardial infarction with DMSO use in stem cell transplantation.
    Neurology, 2007, Mar-13, Volume: 68, Issue:11

    Topics: Brain Injuries; Dimethyl Sulfoxide; Female; Humans; Male; Middle Aged; Myocardial Infarction; Stem C

2007
Dimethyl sulfoxide for the treatment of intracranial hypertension: a preliminary trial.
    Neurosurgery, 1984, Volume: 14, Issue:6

    Topics: Adult; Brain Injuries; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Female; Hematoma, Epidu

1984
Dimethyl sulfoxide therapy following penetrating brain injury.
    Annals of the New York Academy of Sciences, 1983, Volume: 411

    Topics: Animals; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Dimethyl Sulfoxide; Intracrani

1983
Dimethyl sulfoxide in experimental brain injury, with comparison to mannitol.
    Journal of neurosurgery, 1980, Volume: 53, Issue:1

    Topics: Animals; Brain Injuries; Cerebrovascular Circulation; Dimethyl Sulfoxide; Disease Models, Animal; In

1980
DMSO treatment in an experimental cerebral missile injury.
    Surgical forum, 1979, Volume: 30

    Topics: Animals; Brain Injuries; Brain Ischemia; Dimethyl Sulfoxide; Haplorhini; Hypotension; Macaca mulatta

1979
Dimethyl sulfoxide in central nervous system trauma.
    Annals of the New York Academy of Sciences, 1975, Jan-27, Volume: 243

    Topics: Animals; Brain; Brain Injuries; Cerebral Arteries; Craniocerebral Trauma; Dimethyl Sulfoxide; Female

1975
Summary of the dimethyl sulfoxide conference.
    Annals of the New York Academy of Sciences, 1975, Jan-27, Volume: 243

    Topics: Animals; Antineoplastic Agents; Brain Injuries; Dimethyl Sulfoxide; Humans; Neoplasms, Experimental;

1975
Comparative effects of direct and indirect hydroxyl radical scavengers on traumatic brain oedema.
    Acta neurochirurgica. Supplementum, 1990, Volume: 51

    Topics: Animals; Body Water; Brain; Brain Edema; Brain Injuries; Cats; Deferoxamine; Dimethyl Sulfoxide; Fre

1990
An experimental study of craniocerebral trauma during ethanol intoxication.
    Critical care medicine, 1986, Volume: 14, Issue:10

    Topics: Alcoholic Intoxication; Animals; Blood Pressure; Brain Injuries; Dimethyl Sulfoxide; Dogs; Ischemic

1986
Dimethyl sulfoxide in the treatment of experimental brain compression.
    Journal of neurosurgery, 1973, Volume: 38, Issue:3

    Topics: Animals; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Dimethyl Sulfoxide; Disease Mo

1973