dimethyl sulfoxide has been researched along with Autosomal Dominant Striatonigral Degeneration in 1 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Machado-Joseph disease/spinocerebellar ataxia-3 (MJD/SCA-3) is an inherited neurodegenerative disorder caused by expansion of the polyglutamine stretch in the MJD gene-encoded protein ataxin-3." | 1.31 | Chemical chaperones reduce aggregate formation and cell death caused by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch. ( Kanazawa, I; Shibasaki, F; Shoji, S; Yoshida, H; Yoshizawa, T, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshida, H | 1 |
| Yoshizawa, T | 1 |
| Shibasaki, F | 1 |
| Shoji, S | 1 |
| Kanazawa, I | 1 |
1 other study available for dimethyl sulfoxide and Autosomal Dominant Striatonigral Degeneration
| Article | Year |
|---|---|
Chemical chaperones reduce aggregate formation and cell death caused by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ataxin-3; Cell Line; Cricetinae; Dimethyl Sulfoxid | 2002 |