Page last updated: 2024-10-18

dimethyl sulfoxide and Angiospasm, Intracranial

dimethyl sulfoxide has been researched along with Angiospasm, Intracranial in 8 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Research Excerpts

ExcerptRelevanceReference
" In this study, 160 male Sprague-Dawley (SD) rats were randomly assigned into four groups: Sham, subarachnoid hemorrhage (SAH), SAH treated with dimethyl sulfoxide (DMSO) and SAH treated with GSI1."3.76Gamma-secretase inhibitor (GSI1) attenuates morphological cerebral vasospasm in 24h after experimental subarachnoid hemorrhage in rats. ( Chen, C; Hu, Q; Yan, J; Yang, X; Zhou, C, 2010)
"Our data show that SB203580 reversed cerebral vasospasm by inhibiting the phosphorylation of p38 MAPK in the basilar artery and by suppressing the increase in TNF-α in the basilar artery and CSF after SAH."2.78Intracisternal administration of SB203580, a p38 mitogen-activated protein kinase inhibitor, attenuates cerebral vasospasm via inhibition of tumor-necrosis factor-α. ( Chen, KF; Lin, YX; Pan, YX; Shi, JX; Wu, W; Zhang, X; Zhang, XS; Zhou, XM, 2013)
"Inflammation could play a role in cerebral vasospasm after subarachnoid hemorrhage (SAH)."1.33Role of c-Jun N-terminal kinase in cerebral vasospasm after experimental subarachnoid hemorrhage. ( Calvert, JW; Yamaguchi, M; Yatsushige, H; Zhang, JH; Zhou, C, 2005)
"Ras contributes to cerebral vasospasm, and inhibitors of Ras FTase may have potential in the management of cerebral vasospasm."1.32Ras protein contributes to cerebral vasospasm in a canine double-hemorrhage model. ( Nanda, A; Yamaguchi, M; Zhang, JH; Zhou, C, 2004)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gonsales, D1
Gracas, FD1
Santos, R1
Aguilar-Salinas, P1
Hanel, RA1
Pan, YX1
Chen, KF1
Lin, YX1
Wu, W1
Zhou, XM1
Zhang, XS1
Zhang, X1
Shi, JX1
Yang, X1
Chen, C1
Hu, Q1
Yan, J1
Zhou, C3
Kuo, CP1
Lu, CH1
Wen, LL1
Cherng, CH1
Wong, CS1
Borel, CO1
Ju, DT1
Chen, CM1
Wu, CT1
Yamaguchi, M2
Nanda, A1
Zhang, JH3
Yatsushige, H1
Calvert, JW1
Savolainen, H1
Aoki, K1
Zubkov, AY1
Tibbs, RE1

Trials

1 trial available for dimethyl sulfoxide and Angiospasm, Intracranial

ArticleYear
Intracisternal administration of SB203580, a p38 mitogen-activated protein kinase inhibitor, attenuates cerebral vasospasm via inhibition of tumor-necrosis factor-α.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2013, Volume: 20, Issue:5

    Topics: Animals; Basilar Artery; Dimethyl Sulfoxide; Disease Models, Animal; Imidazoles; p38 Mitogen-Activat

2013

Other Studies

7 other studies available for dimethyl sulfoxide and Angiospasm, Intracranial

ArticleYear
Reversible Cerebral Vasoconstriction Syndrome as an Unusual Complication of a Dural Arteriovenous Fistula treated with Onyx Embolization.
    World neurosurgery, 2018, Volume: 115

    Topics: Adolescent; Central Nervous System Vascular Malformations; Dimethyl Sulfoxide; Embolization, Therape

2018
Gamma-secretase inhibitor (GSI1) attenuates morphological cerebral vasospasm in 24h after experimental subarachnoid hemorrhage in rats.
    Neuroscience letters, 2010, Jan-29, Volume: 469, Issue:3

    Topics: Amyloid Precursor Protein Secretases; Animals; Brain; Dimethyl Sulfoxide; Enzyme Inhibitors; Male; N

2010
Neuroprotective effect of curcumin in an experimental rat model of subarachnoid hemorrhage.
    Anesthesiology, 2011, Volume: 115, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Basilar Artery; Blotting, Western; Brain; Catalase

2011
Ras protein contributes to cerebral vasospasm in a canine double-hemorrhage model.
    Stroke, 2004, Volume: 35, Issue:7

    Topics: Alkyl and Aryl Transferases; Animals; Dimethyl Sulfoxide; Dogs; Enzyme Inhibitors; Farnesyltranstran

2004
Role of c-Jun N-terminal kinase in cerebral vasospasm after experimental subarachnoid hemorrhage.
    Stroke, 2005, Volume: 36, Issue:7

    Topics: Angiography; Animals; Anthracenes; Blotting, Western; Cytokines; Dimethyl Sulfoxide; Dogs; Dose-Resp

2005
Encephalopathy, stroke, and myocardial infarction with DMSO use in stem cell transplantation.
    Neurology, 2007, Jul-31, Volume: 69, Issue:5

    Topics: Dimethyl Sulfoxide; Heme; Humans; Hypoxia-Ischemia, Brain; Mitochondria; Myocardial Infarction; Stem

2007
Role of MAPK in chronic cerebral vasospasm.
    Life sciences, 2002, Mar-08, Volume: 70, Issue:16

    Topics: Animals; Blood Pressure; Chronic Disease; Dimethyl Sulfoxide; Dogs; Female; Flavonoids; Male; Mitoge

2002