dimethyl sulfoxide has been researched along with Alloxan Diabetes in 26 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of superoxide dismutase, catalase, metal-chelating agents and hydroxyl radical scavengers on the toxicity of alloxan to isolated ob/ob mouse pancreatic islets in vitro has been compared with the reported ability of such substances to protect against alloxan diabetes in vivo." | 3.70 | Effect of superoxide dismutase, catalase, chelating agents, and free radical scavengers on the toxicity of alloxan to isolated pancreatic islets in vitro. ( Jörns, A; Lenzen, S; Munday, R; Tiedge, M, 1999) |
| "Dimethyl sulfoxide (DMSO), a hydroxyl radical scavenger, is known as an immunosuppressive agent and can reduce autoantibody levels in experimental autoimmune diseases." | 3.67 | Dimethyl sulfoxide modulation of diabetes onset in NOD mice. ( Chirra, AR; DeGruccio, A; Girman, DJ; Klandorf, H, 1989) |
| "ICRF-187, (+)-1,2-bis(3,5-dioxopiperazine-1-yl)propane, has been shown to protect against alloxan diabetes (el-Hage et al." | 3.67 | Mechanism of the protective activity of ICRF-187 against alloxan-induced diabetes in mice. ( Crouch, RK; el-Hage, A; Ferrans, VJ; Herman, EH; Yang, GC, 1986) |
| " Whether long-term use of oral contraceptives would produce ocular complications was queried by Cogan." | 2.35 | Effects of drugs on the lens. ( Paterson, CA, 1971) |
| "The molecular pathogenesis of diabetic nephropathy (DN), the leading cause of end-stage renal disease worldwide, is complex and not fully understood." | 1.35 | Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo. ( Brazil, DP; Carew, RM; Godson, C; Heljic, M; Kattla, JJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (34.62) | 18.7374 |
| 1990's | 8 (30.77) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, W | 1 |
| Qiu, W | 1 |
| Ao, X | 1 |
| Li, W | 1 |
| He, X | 1 |
| Ao, L | 1 |
| Hu, X | 1 |
| Li, Z | 1 |
| Zhu, M | 1 |
| Luo, D | 1 |
| Xing, W | 1 |
| Xu, X | 1 |
| Li, Y | 2 |
| Duan, B | 1 |
| Yu, S | 1 |
| Wang, Y | 1 |
| Bozcaarmutlu, A | 1 |
| Sapmaz, C | 1 |
| Bozdoğan, Ö | 1 |
| Kükner, A | 1 |
| Kılınç, L | 1 |
| Kaya, ST | 1 |
| Özarslan, OT | 1 |
| Ekşioğlu, D | 1 |
| He, M | 1 |
| Long, P | 1 |
| Yan, W | 1 |
| Chen, T | 1 |
| Guo, L | 1 |
| Zhang, Z | 1 |
| Wang, S | 1 |
| Kojayan, G | 1 |
| Whaley, D | 1 |
| Alexander, M | 1 |
| Rodriguez, S | 1 |
| Lee, S | 1 |
| Lakey, JR | 2 |
| Schneider, S | 1 |
| Klein, HH | 1 |
| Salmaso, S | 1 |
| Elvassore, N | 1 |
| Bertucco, A | 1 |
| Caliceti, P | 1 |
| Kattla, JJ | 1 |
| Carew, RM | 1 |
| Heljic, M | 1 |
| Godson, C | 1 |
| Brazil, DP | 1 |
| Nakagawara, G | 1 |
| Kojima, Y | 1 |
| Mizukami, T | 1 |
| Ono, S | 1 |
| Miyazaki, I | 1 |
| Foreman, J | 1 |
| Moriya, H | 1 |
| Taylor, MJ | 1 |
| Rich, SJ | 1 |
| Swift, S | 1 |
| Thirdborough, SM | 1 |
| Rumford, G | 1 |
| James, RF | 1 |
| London, NJ | 1 |
| Korbutt, GS | 2 |
| Ezekowitz, J | 2 |
| Rajotte, MM | 1 |
| Rayat, G | 1 |
| Rajotte, RV | 3 |
| Warnock, GL | 1 |
| Rayat, GR | 1 |
| Jörns, A | 1 |
| Tiedge, M | 1 |
| Lenzen, S | 1 |
| Munday, R | 1 |
| Chen, HC | 1 |
| Guh, JY | 1 |
| Shin, SJ | 1 |
| Tsai, JH | 1 |
| Lai, YH | 1 |
| Heikkila, RE | 1 |
| Birgin, SKh | 1 |
| Afanas'ev, AN | 1 |
| El'kin, GI | 1 |
| Rustemova, GR | 1 |
| Malamud, MIa | 1 |
| Osipova, VV | 1 |
| Jeffery, EH | 1 |
| Arndt, K | 1 |
| Haschek, WM | 1 |
| Vasir, BS | 1 |
| Gray, DW | 1 |
| Morris, PJ | 1 |
| Klandorf, H | 1 |
| Chirra, AR | 1 |
| DeGruccio, A | 1 |
| Girman, DJ | 1 |
| el-Hage, A | 1 |
| Herman, EH | 1 |
| Yang, GC | 1 |
| Crouch, RK | 1 |
| Ferrans, VJ | 1 |
| Jutte, NH | 1 |
| Heyse, P | 1 |
| Jansen, HG | 1 |
| Bruining, GJ | 1 |
| Zeilmaker, GH | 1 |
| Walsh, TN | 1 |
| Alderson, D | 1 |
| Farndon, JR | 1 |
| Paterson, CA | 1 |
1 review available for dimethyl sulfoxide and Alloxan Diabetes
| Article | Year |
|---|---|
Effects of drugs on the lens.
Topics: Adolescent; Adrenal Cortex Hormones; Animals; Antineoplastic Agents; Carbohydrates; Cataract; Contra | 1971 |
25 other studies available for dimethyl sulfoxide and Alloxan Diabetes
| Article | Year |
|---|---|
Low-concentration DMSO accelerates skin wound healing by Akt/mTOR-mediated cell proliferation and migration in diabetic mice.
Topics: Animals; Cell Movement; Cell Proliferation; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Fib | 2020 |
The isoflavonoid calycosin inhibits inflammation and enhances beta cell function in gestational diabetes mellitus by suppressing RNF38 expression.
Topics: Animals; Carrier Proteins; Diabetes Mellitus, Experimental; Diabetes, Gestational; Dimethyl Sulfoxid | 2020 |
The effect of co-administration of berberine, resveratrol, and glibenclamide on xenobiotic metabolizing enzyme activities in diabetic rat liver.
Topics: Animals; Antioxidants; Berberine; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Diabetes Mellitu | 2022 |
ALDH2 attenuates early-stage STZ-induced aged diabetic rats retinas damage via Sirt1/Nrf2 pathway.
Topics: Aldehyde Dehydrogenase, Mitochondrial; Animals; Benzamides; Benzodioxoles; Diabetes Mellitus, Experi | 2018 |
Improved cryopreservation yield of pancreatic islets using combination of lower dose permeable cryoprotective agents.
Topics: Animals; Cryopreservation; Cryoprotective Agents; Diabetes Mellitus, Experimental; Dimethyl Sulfoxid | 2019 |
Preserved insulin secretion capacity and graft function of cryostored encapsulated rat islets.
Topics: Alginates; Animals; Bioartificial Organs; Cryopreservation; Cryoprotective Agents; Diabetes Mellitus | 2011 |
Production of solid lipid submicron particles for protein delivery using a novel supercritical gas-assisted melting atomization process.
Topics: Animals; Blood Glucose; Carbon Dioxide; Chemistry, Pharmaceutical; Chromatography, Supercritical Flu | 2009 |
Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo.
Topics: Animals; Cell Transdifferentiation; Chromones; Diabetes Mellitus, Experimental; Diabetes Mellitus, T | 2008 |
Transplantation of cryopreserved pancreatic islets into the portal vein.
Topics: Animals; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Freezing; Glucagon; Glucose; Insulin; | 1981 |
Effect of cooling rate and its interaction with pre-freeze and post-thaw tissue culture on the in vitro and in vivo function of cryopreserved pancreatic islets.
Topics: Animals; Cell Membrane; Cell Survival; Cells, Cultured; Cryopreservation; Diabetes Mellitus, Experim | 1993 |
Cryopreservation of rat islets of Langerhans: a comparison of two techniques.
Topics: Animals; Cryopreservation; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Evaluation Studies a | 1993 |
Successful cryopreservation of rat islets using ethylene glycol.
Topics: Animals; Cell Culture Techniques; Cell Survival; Cells, Cultured; Cryopreservation; Cryoprotective A | 1997 |
Optimization of removal of cryoprotectant from frozen-thawed islets.
Topics: Animals; Cell Separation; Collagenases; Cryopreservation; Cryoprotective Agents; Diabetes Mellitus, | 1997 |
Cryopreservation of rat pancreatic islets: effect of ethylene glycol on islet function and cellular composition.
Topics: Animals; Blood Glucose; Cell Separation; Cryopreservation; Diabetes Mellitus, Experimental; Dimethyl | 1997 |
Effect of superoxide dismutase, catalase, chelating agents, and free radical scavengers on the toxicity of alloxan to isolated pancreatic islets in vitro.
Topics: 1-Butanol; Alloxan; Animals; Antioxidants; Catalase; Chelating Agents; Deferoxamine; Diabetes Mellit | 1999 |
Reactive oxygen species enhances endothelin-1 production of diabetic rat glomeruli in vitro and in vivo.
Topics: Animals; Catalase; Deferoxamine; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Endothelin-1; | 2000 |
UCLA Conference. Pancreas transplantation for diabetes mellitus.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Female; Fetus; Gestatio | 1978 |
The prevention of alloxan-induced diabetes in mice by dimethyl sulfoxide.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Male; Mice | 1977 |
[Treatment of suppurative-necrotic complications of diabetes mellitus].
Topics: Adult; Aged; Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; F | 1991 |
The role of cytochrome P450IIE1 in bioactivation of acetaminophen in diabetic and acetone-treated mice.
Topics: Acetaminophen; Acetone; Animals; Biotransformation; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme | 1991 |
Normalization of hyperglycemia in diabetic rats by intraportal transplantation of cryopreserved islets from four donors.
Topics: Animals; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Ethidium; Female; Fluoresceins; Freezi | 1989 |
Dimethyl sulfoxide modulation of diabetes onset in NOD mice.
Topics: Animals; Autoimmune Diseases; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Female; Immunosup | 1989 |
Mechanism of the protective activity of ICRF-187 against alloxan-induced diabetes in mice.
Topics: Alloxan; Animals; Blood Glucose; Chelating Agents; Cimetidine; Diabetes Mellitus, Experimental; Dime | 1986 |
Vitrification of mouse islets of Langerhans: comparison with a more conventional freezing method.
Topics: Animals; Blood Glucose; Cryoprotective Agents; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; | 1987 |
Dispersed pancreatic graft cryopreservation in the dog: in vivo assessment of preservation protocols.
Topics: Animals; Cryoprotective Agents; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Dogs; Evaluatio | 1987 |