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dimethyl sulfoxide and Aging

dimethyl sulfoxide has been researched along with Aging in 21 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"The safety and tolerability of a free radical scavenger with Na+ channel blocking activity (dimethyl sulfoxide (DMSO)) combined with a glycolytic intermediate and high energy substrate (fructose 1,6-disphosphate (FDP)) were assessed in a mostly elderly patient group presenting with acute and subacute ischemic stroke."5.10Ischemic stroke in elderly patients treated with a free radical scavenger-glycolytic intermediate solution: a preliminary pilot trial. ( de la Torre, JC; Demir, S; Karaça, M; Kiliç, E; Yazici, B, 2002)
"Dimethyl sulfoxide (DMSO) is a solvent that is routinely used as a cryopreservative in allogous bone marrow and organ transplantation."1.35Dimethyl sulfoxide (DMSO) produces widespread apoptosis in the developing central nervous system. ( Farber, NB; Hanslick, JL; Lau, K; Mennerick, S; Noguchi, KK; Olney, JW; Zorumski, CF, 2009)
"Dimethyl sulfoxide injection has limited stress-induced stimulation of LPO."1.31Lipid peroxidation in the heart of adult and old rats during immobilization stress. ( Davydov, VV; Shvets, VN, 2001)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's5 (23.81)18.2507
2000's6 (28.57)29.6817
2010's4 (19.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Higler, MH1
Brommer, H1
L'Ami, JJ1
de Grauw, JC1
Nielen, M1
van Weeren, PR1
Laverty, S1
Barneveld, A1
Back, W1
Der-Ghazarian, T1
Widarma, CB1
Gutierrez, A1
Amodeo, LR1
Valentine, JM1
Humphrey, DE1
Gonzalez, AE1
Crawford, CA1
McDougall, SA1
Lupp, A1
Glöckner, R1
Etzrodt, J1
Müller, D1
Hanslick, JL1
Lau, K1
Noguchi, KK1
Olney, JW1
Zorumski, CF1
Mennerick, S1
Farber, NB1
Dkhar, P1
Sharma, R1
Assadian Narenji, S1
Naghdi, N1
Oryan, S1
Azadmanesh, K1
BILLINGHAM, RE1
Zakharchenko, IV1
Ovsiannikov, VG1
Davydov, VV2
Westrum, LE1
Jones, DH1
Gray, EG1
Barron, J1
Penn, AL1
Batastini, GG1
Albert, RE1
Martini, R1
Murray, M1
Schilter, B1
Turesky, RJ1
Juillerat, M1
Honegger, P1
Guigoz, Y1
de la Torre, JC2
Nelson, N1
Sutherland, RJ1
Pappas, BA1
Kirk, CJ1
Miller, RA1
Herath, CB1
Watanabe, G1
Katsuda , S1
Yoshida, M1
Suzuki, AK1
Taya, K1
Shvets, VN1
Karaça, M1
Kiliç, E1
Yazici, B1
Demir, S1
Hirsch, GP1
Holland, JM1
Popp, RA1
Viani, A1
Pacifici, GM1
Ganote, CE1
Nayler, WG1
Massie, HR1
Williams, TR1
Iodice, AA1

Reviews

1 review available for dimethyl sulfoxide and Aging

ArticleYear
Contracture and the calcium paradox.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:8

    Topics: 2,4-Dinitrophenol; Aging; Animals; Caffeine; Calcium; Dimethyl Sulfoxide; Dinitrophenols; Freeze Fra

1985

Trials

2 trials available for dimethyl sulfoxide and Aging

ArticleYear
The effects of three-month oral supplementation with a nutraceutical and exercise on the locomotor pattern of aged horses.
    Equine veterinary journal, 2014, Volume: 46, Issue:5

    Topics: Administration, Oral; Aging; Animal Feed; Animals; Anti-Inflammatory Agents; Chondroitin Sulfates; D

2014
Ischemic stroke in elderly patients treated with a free radical scavenger-glycolytic intermediate solution: a preliminary pilot trial.
    Neurological research, 2002, Volume: 24, Issue:1

    Topics: Adult; Aged; Aging; Brain; Brain Edema; Cerebrovascular Circulation; Dimethyl Sulfoxide; Drug Combin

2002

Other Studies

18 other studies available for dimethyl sulfoxide and Aging

ArticleYear
Behavioral effects of dopamine receptor inactivation in the caudate-putamen of preweanling rats: role of the D2 receptor.
    Psychopharmacology, 2014, Volume: 231, Issue:4

    Topics: Aging; Alkylating Agents; Animals; Apomorphine; Benzazepines; Caudate Nucleus; Dimethyl Sulfoxide; D

2014
Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility.
    Analytical and bioanalytical chemistry, 2008, Volume: 392, Issue:6

    Topics: Aging; Animals; Anti-Inflammatory Agents; beta-Naphthoflavone; Coumarins; Cytochrome P-450 CYP1A1; C

2008
Dimethyl sulfoxide (DMSO) produces widespread apoptosis in the developing central nervous system.
    Neurobiology of disease, 2009, Volume: 34, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Apoptosis; Brain; Caspase 3; Cells, Cultured; Dimethyl Sulfoxide;

2009
Effect of dimethylsulphoxide and curcumin on protein carbonyls and reactive oxygen species of cerebral hemispheres of mice as a function of age.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2010, Volume: 28, Issue:5

    Topics: Aging; Animals; Cerebral Cortex; Curcumin; Dimethyl Sulfoxide; Drug Synergism; Female; Free Radical

2010
Effect of 3α-anderostanediol and indomethacin on acquisition, consolidation and retrieval stage of spatial memory in adult male rats.
    Iranian biomedical journal, 2012, Volume: 16, Issue:3

    Topics: Aging; Androstanes; Animals; CA1 Region, Hippocampal; Dimethyl Sulfoxide; Indomethacin; Male; Maze L

2012
SOME PROBLEMS IN ORGAN TRANSPLANTATION.
    Surgery, gynecology & obstetrics, 1965, Volume: 121

    Topics: Aging; Antigens; Cold Temperature; Dimethyl Sulfoxide; Glycerol; Humans; Leukocytes; Tissue Banks; T

1965
[Role of free-radical processes in age-dependent change of energy provision in the liver of rats in stress].
    Advances in gerontology = Uspekhi gerontologii, 2003, Volume: 12

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aging; Animals; Dimethyl Sul

2003
Microtubules, dendritic spines and spine appratuses.
    Cell and tissue research, 1980, Volume: 208, Issue:2

    Topics: Aging; Animals; Cerebral Cortex; Dendrites; Dimethyl Sulfoxide; Histological Techniques; Microscopy,

1980
Age-dependent changes in prevalence, size and proliferation of arterial lesions in cockerels. I. Spontaneous lesions.
    Artery, 1980, Volume: 7, Issue:6

    Topics: Aging; Animals; Aortic Diseases; Arteriosclerosis; Cell Division; Chickens; Dimethyl Sulfoxide; Dise

1980
Retinal dehydrogenation and retinoic acid 4-hydroxylation in rat hepatic microsomes: developmental studies and effect of foreign compounds on the activities.
    Biochemical pharmacology, 1994, Mar-02, Volume: 47, Issue:5

    Topics: Aging; Aldehyde Oxidoreductases; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzym

1994
Phase I and phase II xenobiotic reactions and metabolism of the food-borne carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in aggregating liver cell cultures.
    Biochemical pharmacology, 1993, Mar-09, Volume: 45, Issue:5

    Topics: 7-Alkoxycoumarin O-Dealkylase; Aging; Animals; Cells, Cultured; Dimethyl Sulfoxide; Drug Synergism;

1993
Reversal of ischemic-induced chronic memory dysfunction in aging rats with a free radical scavenger-glycolytic intermediate combination.
    Brain research, 1998, Jan-01, Volume: 779, Issue:1-2

    Topics: Aging; Animals; Arterial Occlusive Diseases; Chronic Disease; Dimethyl Sulfoxide; Drug Therapy, Comb

1998
Age-sensitive and -insensitive pathways leading to JNK activation in mouse CD4(+) T-cells.
    Cellular immunology, 1999, Nov-01, Volume: 197, Issue:2

    Topics: Aging; Animals; CD4-Positive T-Lymphocytes; Cells, Cultured; Ceramides; Colforsin; Cyclosporine; Dim

1999
Exposure of neonatal female rats to p-tert-octylphenol disrupts afternoon surges of luteinizing hormone, follicle-stimulating hormone and prolactin secretion, and interferes with sexual receptive behavior in adulthood.
    Biology of reproduction, 2001, Volume: 64, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Circadian Rhythm; Dimethyl Sulfoxide; Drug Implants; Estradiol; Fe

2001
Lipid peroxidation in the heart of adult and old rats during immobilization stress.
    Experimental gerontology, 2001, Volume: 36, Issue:7

    Topics: Aging; Animals; Dimethyl Sulfoxide; Free Radical Scavengers; Lipid Peroxidation; Male; Myocardium; R

2001
Amino acid analog incorporation into protein in dimethyl sulfoxide and mutagen-treated aging mice.
    Birth defects original article series, 1978, Volume: 14, Issue:1

    Topics: Aging; Aminoisobutyric Acids; Animals; Dimethyl Sulfoxide; Female; Genetic Code; Hemoglobins; Leucin

1978
Quantitative contribution of endogenous compounds and hypoalbuminemia in reducing the binding of furosemide in the plasma of newborn infants.
    Developmental pharmacology and therapeutics, 1992, Volume: 18, Issue:1-2

    Topics: Aging; Apazone; Dialysis; Dimethyl Sulfoxide; Furosemide; Humans; Infant, Newborn; Protein Binding;

1992
Influence of anti-inflammatory agents on the survival of Drosophila.
    Journal of gerontology, 1985, Volume: 40, Issue:3

    Topics: Aging; Animals; Anti-Inflammatory Agents; Chlorpromazine; Copper; Dimethyl Sulfoxide; Drosophila mel

1985