dimethyl sulfoxide has been researched along with Abnormalities, Drug-Induced in 38 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dose-response of the teratogenic effect of caffeine (CA) and the potential role of facial hematomas in the pathogenesis of caffeine-induced cleft palate were investigated using CD1 mice treated with 150, 200, or 250 mg CA/kg i." | 3.69 | Interaction of dimethylsulfoxide and arachidonic acid with the teratogenic effects of caffeine in mice. ( Brimer, GE; Fraipier, BL; Frappier, BL; Reddy, CS; Reddy, RV, 1994) |
| "Petroleum creosote, dissolved in dimethyl sulfoxide, was administered by gavage to pregnant ICR mice on days 5-9 of gestation at a single dose (400 mg/kg body weight per day)." | 3.68 | Developmental effects of petroleum creosote on mice following oral exposure. ( Irvin, TR; Iyer, PR; Martin, JE, 1993) |
| " on day 11 of pregnancy in either 5% (w/v) NaHCO3 or 20% (v/v) dimethyl sulfoxide (DMSO) in NaHCO3." | 3.68 | Role of maternal plasma corticosterone elevation in the teratogenicity of secalonic acid D in mice. ( Eldeib, MM; Reddy, CS, 1990) |
| "Dimethyl sulfoxide (DMSO), a widely used carrier solvent, can be toxic to test organisms and has species-specific sensitivity." | 1.46 | Comparative Developmental Toxicity and Stress Protein Responses of Dimethyl Sulfoxide to Rare Minnow and Zebrafish Embryos/Larvae. ( Luo, S; Wang, J; Wu, B; Xiong, X, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (73.68) | 18.7374 |
| 1990's | 7 (18.42) | 18.2507 |
| 2000's | 2 (5.26) | 29.6817 |
| 2010's | 1 (2.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiong, X | 1 |
| Luo, S | 1 |
| Wu, B | 1 |
| Wang, J | 1 |
| CAUJOLLE, F | 1 |
| CAUJOLLE, D | 1 |
| CROS, S | 2 |
| CALVET, M | 1 |
| TOLLON, Y | 2 |
| Hallare, A | 1 |
| Nagel, K | 1 |
| Köhler, HR | 1 |
| Triebskorn, R | 1 |
| Pérez-Pastén, R | 1 |
| Martínez-Galero, E | 1 |
| Garduño-Siciliano, L | 1 |
| Lara, IC | 1 |
| Cevallos, GC | 1 |
| Budennaia, MP | 1 |
| Alsup, EM | 1 |
| DeBowes, RM | 1 |
| Schultz, TW | 1 |
| Dumont, JN | 1 |
| Buchanan, MV | 1 |
| Reddy, RV | 1 |
| Reddy, CS | 2 |
| Frappier, BL | 1 |
| Brimer, GE | 1 |
| Fraipier, BL | 1 |
| Iyer, PR | 1 |
| Irvin, TR | 1 |
| Martin, JE | 1 |
| Lanot, R | 2 |
| Cordonnier, JL | 1 |
| Meiniel, R | 1 |
| Dix, KM | 1 |
| van der Pauw, CL | 1 |
| McCarthy, WV | 1 |
| Strange, JR | 2 |
| Allred, PM | 1 |
| Kerr, WE | 2 |
| Mirapeix, RM | 1 |
| Domenech-Mateu, JM | 1 |
| Dresser, TH | 1 |
| Rivera, ER | 1 |
| Hoffmann, FJ | 1 |
| Finch, RA | 1 |
| Okishima, T | 1 |
| Takamura, K | 1 |
| Matsuoka, Y | 1 |
| Ohdo, S | 1 |
| Hayakawa, K | 1 |
| Brennan, SM | 1 |
| Eldeib, MM | 1 |
| Larsen, HL | 1 |
| Janners, MY | 1 |
| Bossert, NL | 1 |
| Iannaccone, PM | 1 |
| Ferm, VH | 2 |
| Montuori, E | 1 |
| Adler, R | 1 |
| Landauer, W | 1 |
| Salam, N | 1 |
| Mawhinney, BS | 1 |
| Schenken, LL | 1 |
| David, NA | 1 |
| Gilani, SH | 1 |
| Beger, I | 1 |
| Hauthal, HG | 1 |
| Caujolle, FM | 1 |
| Caujolle, DH | 1 |
| Cros, SB | 1 |
| Calvet, MM | 1 |
| Courtney, KD | 1 |
| Gaylor, DW | 1 |
| Hogan, MD | 1 |
| Falk, HL | 1 |
| Bates, RR | 1 |
| Mitchell, I | 1 |
| Voisin, MC | 1 |
| Oreglia, J | 1 |
| Schumacher, H | 1 |
| Blake, DA | 1 |
| Gurian, JM | 1 |
| Gillette, JR | 1 |
| Leidl, W | 1 |
| Biergert, W | 1 |
| Robens, JF | 1 |
| Stenchever, MA | 1 |
| Frankel, RB | 1 |
| Marin-Padilla, M | 1 |
3 reviews available for dimethyl sulfoxide and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Use of dimethyl sulfoxide in medicine and biology (a review of the literature)].
Topics: Abnormalities, Drug-Induced; Animals; Anti-Infective Agents, Local; Chemical Phenomena; Chemistry; C | 1983 |
The pharmacology of dimethyl sulfoxide.
Topics: Abnormalities, Drug-Induced; Absorption; Analgesics; Animals; Anti-Inflammatory Agents; Anura; Biolo | 1972 |
[Dimethylsulfoxide in medicine and pharmacology].
Topics: Abnormalities, Drug-Induced; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Dimethyl Sulfoxi | 1968 |
35 other studies available for dimethyl sulfoxide and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Comparative Developmental Toxicity and Stress Protein Responses of Dimethyl Sulfoxide to Rare Minnow and Zebrafish Embryos/Larvae.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cyprinidae; Dimethyl Sulfoxide; Dose-Response Rel | 2017 |
[TERATOGENIC POWER OF DIMETHYLSULFOXIDE AND DIETHYLSULFOXIDE].
Topics: Abnormalities, Drug-Induced; Anophthalmos; Chick Embryo; Dimethyl Sulfoxide; Ectromelia; Mice; Rabbi | 1965 |
Comparative embryotoxicity and proteotoxicity of three carrier solvents to zebrafish (Danio rerio) embryos.
Topics: Abnormalities, Drug-Induced; Acetone; Animals; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; | 2006 |
Effects of dimethylsulphoxide on mice arsenite-induced dysmorphogenesis in embryo culture and cytotoxicity in embryo cells.
Topics: Abnormalities, Drug-Induced; Animals; Arsenites; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; | 2006 |
Dimethyl sulfoxide.
Topics: Abnormalities, Drug-Induced; Analgesics; Animals; Anti-Infective Agents; Biological Transport; Centr | 1984 |
Toxic and teratogenic effects of chemical class fractions of a coal-gasification electrostatic precipitator tar.
Topics: Abnormalities, Drug-Induced; Animals; Coal; Dimethyl Sulfoxide; Female; Gases; Pregnancy; Tars; Xeno | 1983 |
Interaction of dimethylsulfoxide and arachidonic acid with the teratogenic effects of caffeine in mice.
Topics: Abnormalities, Drug-Induced; Animals; Arachidonic Acid; Caffeine; Cleft Palate; Corticosterone; Dime | 1994 |
Developmental effects of petroleum creosote on mice following oral exposure.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Body Weight; Creosote; Dimethyl Sulfoxid | 1993 |
[Early teratogen effect of neutral desoxyribonuclase on young chick embryo].
Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Cell Differentiation; Chick Embryo; Deoxyribonucl | 1975 |
[Parathion axial teratogenesis after giving several compounds with known anti-teratogenic or antitoxic properties in vertebrate adults or embryos after exposure to organic phosphates. Study in the quail embryo (Coturnix coturnix japonica)].
Topics: Abnormalities, Drug-Induced; Animals; Atropine; Coturnix; Dimethyl Sulfoxide; Neck; Oximes; Parathio | 1976 |
Toxicity studies with dieldrin: teratological studies in mice dosed orally with HEOD.
Topics: Abnormalities, Drug-Induced; Animals; Dieldrin; Dimethyl Sulfoxide; Female; Fetus; Mice; Osteogenesi | 1977 |
Teratogenic and toxicological effects of 2,4,5--trichlorophenoxyacetic acid in developing chick embryos.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Acetone; Animals; Chick Embryo; Dime | 1976 |
Teratogenic and toxicological examination of 2,4,5-trichlorphenoxyacetic acid in developing chick embryos.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Chick Embryo; Dimethyl Sulf | 1976 |
[Anomalies produced by cytochalasin B after 10.5 days of gestation: in vitro study].
Topics: Abnormalities, Drug-Induced; Animals; Culture Techniques; Cytochalasin B; Dimethyl Sulfoxide; Embryo | 1992 |
Teratogenic assessment of four solvents using the Frog Embryo Teratogenesis Assay--Xenopus (FETAX).
Topics: Abnormalities, Drug-Induced; Animals; Dimethyl Sulfoxide; Dioxolanes; Embryonic and Fetal Developmen | 1992 |
Cardiovascular anomalies in chick embryos produced by bis-diamine in dimethylsulfoxide.
Topics: Abnormalities, Drug-Induced; Animals; Cell Death; Chick Embryo; Chickens; Chimera; Diamines; Dimethy | 1992 |
Morphogenetic and molecular correlates of teratogenesis in the amphibian embryo.
Topics: Abnormalities, Drug-Induced; Actins; Animals; Dimethyl Sulfoxide; DNA; RNA Probes; RNA, Messenger; R | 1991 |
Role of maternal plasma corticosterone elevation in the teratogenicity of secalonic acid D in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Corticosterone; Dimethyl Sulfoxide; Dose-Respons | 1990 |
Teratogenic effects of retinoic acid and dimethylsulfoxide on embryonic chick wing and somite.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Chick Embryo; Dimethyl Sulfoxide; Dose-Respons | 1987 |
Midgestational abnormalities associated with in vitro preimplantation N-methyl-N-nitrosourea exposure with subsequent transfer to surrogate mothers.
Topics: Abnormalities, Drug-Induced; Animals; Blastocyst; Dimethyl Sulfoxide; Embryo Transfer; Embryonic Dev | 1985 |
Teratogenic effect of dimethyl sulphoxide.
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Dimethyl Sulfoxide; Female; Injections, Intraperit | 1966 |
[Action of dimethylsulphoxide on the chick embryo].
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Dimethyl Sulfoxide | 1967 |
Aspects of dimethyl sulfoxide as solvent for teratogens.
Topics: Abnormalities, Drug-Induced; Acetates; Amines; Animals; Butyrates; Chick Embryo; Dimethyl Sulfoxide; | 1972 |
Modification of radiation response and teratogenic action by dimethyl sulphoxide in chick embryos.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Chick Embryo; Dimethyl Sulfoxide; Gestational Age | 1972 |
Cardiovascular malformations in the chick embryo induced by thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; Aortic Arch Syndromes; Aortic Valve Stenosis; Cardiovascular A | 1973 |
[Early teratogenic action of dimethyl sulfoxide in the chick embryo].
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Dimethyl Sulfoxide; Female; Gestational Age; Pre | 1973 |
Limits of toxic and teratogenic tolerance of dimethyl sulfoxide.
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Dimethyl Sulfoxide; Dogs; Drug Tolerance; Female; | 1967 |
Teratogenic evaluation of 2,4,5-T.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Dimethyl Sulfoxide; Female; Fetal Death; Fetus; | 1970 |
[Damage of limb buds of chicken embryos by dimethyl sulfoxide].
Topics: Abnormalities, Drug-Induced; Animals; Capillaries; Chick Embryo; Dimethyl Sulfoxide; Extremities; He | 1970 |
A comparison of the teratogenic activity of thalidomide in rabbits and rats.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Dimethyl Sulfoxide; Embryo Implantation; Femal | 1968 |
Tissue tolerance and drug transport studies of DMSO applied to the gonads of bulls and boars.
Topics: Abnormalities, Drug-Induced; Animals; Biological Transport; Cattle; Dimethyl Sulfoxide; Epididymis; | 1968 |
Teratologic studies of carbaryl, diazinon, norea, disulfiram, and thiram in small laboratory animals.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Infective Agents, Local; Bone and Bones; Carbamates; Cric | 1969 |
Some effects of diazepam in human cells in vitro.
Topics: Abnormalities, Drug-Induced; Chromosomes; Culture Techniques; Dimethyl Sulfoxide; Embryo, Mammalian; | 1969 |
Mesodermal alterations induced by dimethyl sulfoxide.
Topics: Abnormalities, Drug-Induced; Anencephaly; Animals; Cricetinae; Dimethyl Sulfoxide; Embryo, Mammalian | 1966 |
Congenital malformations induced by dimethyl sulphoxide in the golden hamster.
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Dimethyl Sulfoxide; Embryo, Mammalian; Female; Ner | 1966 |