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dimethyl sulfide and Cystinosis

dimethyl sulfide has been researched along with Cystinosis in 4 studies

dimethyl sulfide: structure
dimethyl sulfide : A methyl sulfide in which the sulfur atom is substituted by two methyl groups. It is produced naturally by some marine algae.
methyl sulfide : Any aliphatic sulfide in which at least one of the organyl groups attached to the sulfur is a methyl group.

Cystinosis: A metabolic disease characterized by the defective transport of CYSTINE across the lysosomal membrane due to mutation of a membrane protein cystinosin. This results in cystine accumulation and crystallization in the cells causing widespread tissue damage. In the KIDNEY, nephropathic cystinosis is a common cause of RENAL FANCONI SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"Halitosis due to dimethylsulfide (DMS) generation is a major side effect of cysteamine in the treatment of cystinosis."7.78Halitosis in cystinosis patients after administration of immediate-release cysteamine bitartrate compared to delayed-release cysteamine bitartrate. ( Besouw, M; Cornelissen, E; Levtchenko, E; Rioux, P; Tangerman, A, 2012)
"To identify breath sulphur compounds causing halitosis induced by cysteamine therapy in patients with cystinosis."7.74The origin of halitosis in cystinotic patients due to cysteamine treatment. ( Besouw, M; Blom, H; de Graaf-Hess, A; Levtchenko, E; Tangerman, A, 2007)
"Cystinosis is a genetic disorder caused by malfunction of cystinosin and is characterized by accumulation of cystine."5.46Evaluation of carbohydrate-cysteamine thiazolidines as pro-drugs for the treatment of cystinosis. ( Hartman, TM; Ivanova, EA; Levtchenko, EN; Pastore, A; Paul, P; Price, NPJ; Ramazani, Y; Van Den Heuvel, L; Van Schepdael, A, 2017)
"When cysteamine was given every 6 h, the leukocyte cystine concentration, measured 5-7 h after a dose, decreased with increasing cysteamine doses up to 17 mg/kg; at this dose the cystine value was 1."5.29Intravenous cysteamine therapy for nephropathic cystinosis. ( Bernardini, I; Gahl, WA; Hyman, PE; Ingelfinger, J; Mohan, P; Tangerman, A, 1995)
"Halitosis due to dimethylsulfide (DMS) generation is a major side effect of cysteamine in the treatment of cystinosis."3.78Halitosis in cystinosis patients after administration of immediate-release cysteamine bitartrate compared to delayed-release cysteamine bitartrate. ( Besouw, M; Cornelissen, E; Levtchenko, E; Rioux, P; Tangerman, A, 2012)
"To identify breath sulphur compounds causing halitosis induced by cysteamine therapy in patients with cystinosis."3.74The origin of halitosis in cystinotic patients due to cysteamine treatment. ( Besouw, M; Blom, H; de Graaf-Hess, A; Levtchenko, E; Tangerman, A, 2007)
"Cystinosis is a genetic disorder caused by malfunction of cystinosin and is characterized by accumulation of cystine."1.46Evaluation of carbohydrate-cysteamine thiazolidines as pro-drugs for the treatment of cystinosis. ( Hartman, TM; Ivanova, EA; Levtchenko, EN; Pastore, A; Paul, P; Price, NPJ; Ramazani, Y; Van Den Heuvel, L; Van Schepdael, A, 2017)
"When cysteamine was given every 6 h, the leukocyte cystine concentration, measured 5-7 h after a dose, decreased with increasing cysteamine doses up to 17 mg/kg; at this dose the cystine value was 1."1.29Intravenous cysteamine therapy for nephropathic cystinosis. ( Bernardini, I; Gahl, WA; Hyman, PE; Ingelfinger, J; Mohan, P; Tangerman, A, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ramazani, Y1
Levtchenko, EN1
Van Den Heuvel, L1
Van Schepdael, A1
Paul, P1
Ivanova, EA1
Pastore, A1
Hartman, TM1
Price, NPJ1
Besouw, M2
Tangerman, A3
Cornelissen, E1
Rioux, P1
Levtchenko, E2
Blom, H1
de Graaf-Hess, A1
Gahl, WA1
Ingelfinger, J1
Mohan, P1
Bernardini, I1
Hyman, PE1

Other Studies

4 other studies available for dimethyl sulfide and Cystinosis

ArticleYear
Evaluation of carbohydrate-cysteamine thiazolidines as pro-drugs for the treatment of cystinosis.
    Carbohydrate research, 2017, Feb-01, Volume: 439

    Topics: Arabinose; Biotransformation; Cysteamine; Cystine Depleting Agents; Cystinosis; Drug Design; Extrace

2017
Halitosis in cystinosis patients after administration of immediate-release cysteamine bitartrate compared to delayed-release cysteamine bitartrate.
    Molecular genetics and metabolism, 2012, Volume: 107, Issue:1-2

    Topics: Adolescent; Child; Cysteamine; Cystinosis; Exhalation; Halitosis; Humans; Male; Sulfides; Young Adul

2012
The origin of halitosis in cystinotic patients due to cysteamine treatment.
    Molecular genetics and metabolism, 2007, Volume: 91, Issue:3

    Topics: Adolescent; Adult; Breath Tests; Child; Cysteamine; Cystinosis; Female; Halitosis; Humans; Male; Sul

2007
Intravenous cysteamine therapy for nephropathic cystinosis.
    Pediatric research, 1995, Volume: 38, Issue:4

    Topics: Child, Preschool; Cysteamine; Cystine; Cystinosis; Gastrointestinal Diseases; Gastrointestinal Motil

1995