dimethyl-maleate and Neoplasms

dimethyl-maleate has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for dimethyl-maleate and Neoplasms

ArticleYear
A novel pH-responsive polysaccharidic ionic complex for proapoptotic D-(KLAKLAK)2 peptide delivery.
    Chemical communications (Cambridge, England), 2011, Apr-07, Volume: 47, Issue:13

    We report charge-switching ionic nanocomplexes comprised of glycol chitosan grafted with 2,3-dimethylmaleic acid (DMA) (denoted as 'GCS-g-DMA' hereafter) and a proapoptotic peptide. This system allowed for improved peptide delivery to tumor sites via a mechanism of selective peptide release when the pH was dropped from 7.4 to 6.8.

    Topics: Animals; Antineoplastic Agents; Chitosan; Drug Carriers; Female; Humans; Hydrogen-Ion Concentration; Maleates; Melanoma, Experimental; Mice; Neoplasms; Peptides

2011