dimethyl-maleate has been researched along with Neoplasms* in 1 studies
1 other study(ies) available for dimethyl-maleate and Neoplasms
Article | Year |
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A novel pH-responsive polysaccharidic ionic complex for proapoptotic D-(KLAKLAK)2 peptide delivery.
We report charge-switching ionic nanocomplexes comprised of glycol chitosan grafted with 2,3-dimethylmaleic acid (DMA) (denoted as 'GCS-g-DMA' hereafter) and a proapoptotic peptide. This system allowed for improved peptide delivery to tumor sites via a mechanism of selective peptide release when the pH was dropped from 7.4 to 6.8. Topics: Animals; Antineoplastic Agents; Chitosan; Drug Carriers; Female; Humans; Hydrogen-Ion Concentration; Maleates; Melanoma, Experimental; Mice; Neoplasms; Peptides | 2011 |