dimethyl itaconate has been researched along with Innate Inflammatory Response in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 8 (72.73) | 2.80 |
| Authors | Studies |
|---|---|
| Abd El-Aty, AM; Hacimuftuoglu, A; Jeong, JH; Jung, TW; Lee, HJ; Park, SY; Ramadan, A; Shin, YK; Song, JH | 1 |
| Cui, Z; Huang, B; Li, L; Wang, H; Yang, Y | 1 |
| Fan, Y; Gu, L; Li, C; Lin, H; Lin, J; Lu, C; Niu, Y; Peng, X; Wang, Q; Zhao, G; Zhu, G | 1 |
| Brown, DA; Kuo, PC; Paraiso, HC; Scofield, BA; Wang, PY; Weng, WT; Yen, JH; Yu, IC | 1 |
| Jia, H; Jiao, Y; Li, C; Liang, X; Nie, Z; Zhang, S; Zhang, Y | 1 |
| Duan, Y; Gao, C; Lu, L; Mao, Z; Nakkala, JR; Yao, Y; Zhai, Z; Zhang, D | 1 |
| Kang, YY; Lan, JQ; Peng, Y; Tang, JS; Wu, L; Zhang, Y; Zhou, YJ | 1 |
| Chen, X; Huang, L; Lin, X; Yang, S; Zhang, H; Zhang, X; Zhang, Y; Zhuge, Q | 1 |
| Akira, S; Amarasinghe, GK; Apte, RS; Artyomov, MN; Auclair, K; Bambouskova, M; Biller, SA; Bregman, H; de Guzman Strong, C; Duncan, D; Gorvel, L; Hai, T; Huang, LH; Johnson, B; Johnson, K; Jovanovic, M; Keskin, A; Kim, H; Klechevsky, E; Korenfeld, D; Lampropoulou, V; Loginicheva, E; Mathyer, ME; Randolph, GJ; Roddy, TP; Santeford, A; Satoh, T; Sehgal, R; Sergushichev, A; Soares, MP; Stewart, KM | 1 |
| Cao, Y; Fu, Y; Guo, J; He, Z; Hu, X; Jiang, P; Li, Y; Yuan, X; Zhang, N; Zhao, C | 1 |
| Burant, CF; ElAzzouny, M; Evans, CR; Gallagher, KA; Martin, BR; Olson, LL; Tanga, MJ; Tom, CT | 1 |
1 trial(s) available for dimethyl itaconate and Innate Inflammatory Response
| Article | Year |
|---|---|
Protective effects of dietary dimethyl itaconate supplementation on oxidative stress, inflammation, and apoptosis in broilers under chronic heat stress.
Topics: Animal Feed; Animals; Antioxidants; Apoptosis; Chickens; Diet; Dietary Supplements; Heat-Shock Response; Inflammation; Male; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger | 2023 |
10 other study(ies) available for dimethyl itaconate and Innate Inflammatory Response
| Article | Year |
|---|---|
Dimethyl itaconate attenuates palmitate-induced insulin resistance in skeletal muscle cells through the AMPK/FGF21/PPARδ-mediated suppression of inflammation.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Cell Line; Dose-Response Relationship, Drug; Fibroblast Growth Factors; Inflammation; Insulin Resistance; Mice; Muscle Fibers, Skeletal; Palmitates; PPAR delta; Succinates | 2021 |
Dimethyl itaconate protects against fungal keratitis by activating the Nrf2/HO-1 signaling pathway.
Topics: Animals; Aspergillosis; Aspergillus fumigatus; Chemokine CXCL1; Cornea; Epithelial Cells; Epithelium, Corneal; Heme Oxygenase-1; Humans; Inflammation; Interleukin-6; Interleukin-8; Keratitis; Mice; NF-E2-Related Factor 2; Signal Transduction; Succinates | 2020 |
Dimethyl itaconate, an itaconate derivative, exhibits immunomodulatory effects on neuroinflammation in experimental autoimmune encephalomyelitis.
Topics: Animals; Anti-Inflammatory Agents; Blood-Brain Barrier; Encephalomyelitis, Autoimmune, Experimental; Inflammation; Mice; Mice, Inbred C57BL; Microglia; Spinal Cord; Succinates | 2020 |
Dimethyl Itaconate Alleviates the Inflammatory Responses of Macrophages in Sepsis.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Blotting, Western; Cytokines; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; Sepsis; Succinates | 2021 |
Dimethyl Itaconate-Loaded Nanofibers Rewrite Macrophage Polarization, Reduce Inflammation, and Enhance Repair of Myocardic Infarction.
Topics: Animals; Infarction; Inflammation; Macrophages; Mice; Nanofibers; Succinates | 2021 |
A comparison study between dimethyl itaconate and dimethyl fumarate in electrophilicity, Nrf2 activation, and anti-inflammation
Topics: Anti-Inflammatory Agents; Dimethyl Fumarate; Humans; Inflammation; Molecular Structure; NF-E2-Related Factor 2; Succinates | 2022 |
Dimethyl itaconate inhibits LPS‑induced microglia inflammation and inflammasome‑mediated pyroptosis via inducing autophagy and regulating the Nrf‑2/HO‑1 signaling pathway.
Topics: Animals; Autophagy; Cell Line; Cell Survival; Heme Oxygenase-1; Inflammasomes; Inflammation; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Microglia; NF-E2-Related Factor 2; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphate-Binding Proteins; Primary Cell Culture; Protective Agents; Pyroptosis; Reactive Oxygen Species; Signal Transduction; Succinates | 2021 |
Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.
Topics: Activating Transcription Factor 3; Animals; Cells, Cultured; Cytokines; Female; Gene Expression Regulation; Glutathione; Humans; I-kappa B Proteins; Inflammation; Interleukin-6; Keratinocytes; Macrophages; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Psoriasis; Stress, Physiological; Succinates; Toll-Like Receptors | 2018 |
Dimethyl itaconate protects against lippolysacchride-induced mastitis in mice by activating MAPKs and Nrf2 and inhibiting NF-κB signaling pathways.
Topics: Animals; Cytokines; Disease Models, Animal; Down-Regulation; Female; Heme Oxygenase-1; Humans; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Mammary Glands, Human; MAP Kinase Signaling System; Mastitis; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase Kinases; NF-E2-Related Factor 2; NF-kappa B; Phosphorylation; Protective Agents; Signal Transduction; Succinates; Toll-Like Receptor 4; Transcription Factor RelA; Up-Regulation | 2019 |
Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly.
Topics: Animals; Cells, Cultured; Inflammation; Lipopolysaccharides; Macrophages; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; RAW 264.7 Cells; Succinates; Succinic Acid | 2017 |