dimethoate has been researched along with Myasthenia Gravis in 2 studies
Dimethoate: An organothiophosphorus cholinesterase inhibitor that is used as a systemic and contact insecticide.
dimethoate : A monocarboxylic acid amide that is N-methylacetamide in which one of the hydrogens of the methyl group attached to the carbonyl moiety is replaced by a (dimethoxyphosphorothioyl)sulfanediyl group.
Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Muscle weakness was associated with neuromuscular transmission dysfunction, but not well correlated with ChE inhibition." | 1.31 | [Stimulation single fiber electromyography in rats with myasthenia induced by organophosphorus insecticides and their mixtures poisoning]. ( He, F; Niu, Y; Xiao, C, 2002) |
| " The result showed that c-fos mRNA and protein were significantly increased in skeletal muscle of rat after dosing with dimethoate." | 1.30 | [Effect of dimethoate on the expression of c-fos gene in skeletal muscle]. ( He, F; Niu, Y; Yang, D, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiao, C | 1 |
| Niu, Y | 2 |
| He, F | 2 |
| Yang, D | 1 |
2 other studies available for dimethoate and Myasthenia Gravis
| Article | Year |
|---|---|
[Stimulation single fiber electromyography in rats with myasthenia induced by organophosphorus insecticides and their mixtures poisoning].
Topics: Animals; Cholinesterase Inhibitors; Dimethoate; Electromyography; Insecticides; Methomyl; Muscle Wea | 2002 |
[Effect of dimethoate on the expression of c-fos gene in skeletal muscle].
Topics: Animals; Dimethoate; Genes, Immediate-Early; Immediate-Early Proteins; Insecticides; Male; Muscle, S | 1999 |