dimethadione has been researched along with Hepatic Encephalopathy in 1 studies
Dimethadione: An anticonvulsant that is the active metabolite of TRIMETHADIONE.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the adequacy of the trimethadione (TMO) tolerance test (the method of estimation from the serum dimethadione [DMO]/TMO ratio, DMO is only one metabolite of TMO, at 4 hours after oral administration of TMO) for estimating the severity of liver damage in 40 cirrhotic patients with and without hepatic encephalopathy." | 3.68 | Trimethadione tolerance test for one-point estimation of the severity of liver damage in cirrhotic patients. ( Abei, M; Adachi, S; Fukao, K; Ishikawa, A; Iwasaki, Y; Osada, A; Takase, Y; Tanaka, E; Tsuji, K; Yamamoto, Y, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanaka, E | 1 |
| Ishikawa, A | 1 |
| Fukao, K | 1 |
| Tsuji, K | 1 |
| Osada, A | 1 |
| Yamamoto, Y | 1 |
| Adachi, S | 1 |
| Takase, Y | 1 |
| Abei, M | 1 |
| Iwasaki, Y | 1 |
1 other study available for dimethadione and Hepatic Encephalopathy
| Article | Year |
|---|---|
Trimethadione tolerance test for one-point estimation of the severity of liver damage in cirrhotic patients.
Topics: Dimethadione; Female; Hepatic Encephalopathy; Humans; Indocyanine Green; Liver Cirrhosis; Liver Func | 1991 |