dimethadione has been researched along with Glioma in 3 studies
Dimethadione: An anticonvulsant that is the active metabolite of TRIMETHADIONE.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We measured the extracellular (interstitial) pH (pHe) of RG-2 rat gliomas using H+-sensitive microelectrodes and estimated the volume of tumor extracellular space based on the tissue-plasma ratio of [14C]sucrose." | 3.67 | In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. II: Characterization of the extracellular fluid compartment using pH-sensitive microelectrodes and [14C]sucrose. ( Arnold, JB; Kraig, RP; Rottenberg, DA, 1986) |
| "Thus, the RG-2 glioma is not more "acidic" than adjacent brain tissue and its "alkaline" pHt probably reflects a large extracellular water content and plasma-like extracellular pH." | 1.27 | In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. ( Arnold, JB; Junck, L; Rottenberg, DA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lomneth, R | 1 |
| Medrano, S | 1 |
| Gruenstein, EI | 1 |
| Arnold, JB | 2 |
| Kraig, RP | 1 |
| Rottenberg, DA | 2 |
| Junck, L | 1 |
3 other studies available for dimethadione and Glioma
| Article | Year |
|---|---|
The role of transmembrane pH gradients in the lactic acid induced swelling of astrocytes.
Topics: Alanine; Astrocytes; Brain Neoplasms; Cell Membrane; Dimethadione; Glioma; Humans; Hydrogen-Ion Conc | 1990 |
In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. II: Characterization of the extracellular fluid compartment using pH-sensitive microelectrodes and [14C]sucrose.
Topics: Animals; Autoradiography; Brain; Brain Neoplasms; Dimethadione; Extracellular Space; Glioma; Hydroge | 1986 |
In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography.
Topics: Animals; Autoradiography; Brain Chemistry; Brain Neoplasms; Carbon Radioisotopes; Dimethadione; Extr | 1985 |