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dimethadione and Glial Cell Tumors

dimethadione has been researched along with Glial Cell Tumors in 3 studies

Dimethadione: An anticonvulsant that is the active metabolite of TRIMETHADIONE.

Research Excerpts

ExcerptRelevanceReference
"We measured the extracellular (interstitial) pH (pHe) of RG-2 rat gliomas using H+-sensitive microelectrodes and estimated the volume of tumor extracellular space based on the tissue-plasma ratio of [14C]sucrose."3.67In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. II: Characterization of the extracellular fluid compartment using pH-sensitive microelectrodes and [14C]sucrose. ( Arnold, JB; Kraig, RP; Rottenberg, DA, 1986)
"Thus, the RG-2 glioma is not more "acidic" than adjacent brain tissue and its "alkaline" pHt probably reflects a large extracellular water content and plasma-like extracellular pH."1.27In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. ( Arnold, JB; Junck, L; Rottenberg, DA, 1985)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lomneth, R1
Medrano, S1
Gruenstein, EI1
Arnold, JB2
Kraig, RP1
Rottenberg, DA2
Junck, L1

Other Studies

3 other studies available for dimethadione and Glial Cell Tumors

ArticleYear
The role of transmembrane pH gradients in the lactic acid induced swelling of astrocytes.
    Brain research, 1990, Jul-16, Volume: 523, Issue:1

    Topics: Alanine; Astrocytes; Brain Neoplasms; Cell Membrane; Dimethadione; Glioma; Humans; Hydrogen-Ion Conc

1990
In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. II: Characterization of the extracellular fluid compartment using pH-sensitive microelectrodes and [14C]sucrose.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:4

    Topics: Animals; Autoradiography; Brain; Brain Neoplasms; Dimethadione; Extracellular Space; Glioma; Hydroge

1986
In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1985, Volume: 5, Issue:3

    Topics: Animals; Autoradiography; Brain Chemistry; Brain Neoplasms; Carbon Radioisotopes; Dimethadione; Extr

1985