dimethadione has been researched along with Brain Neoplasms in 5 studies
Dimethadione: An anticonvulsant that is the active metabolite of TRIMETHADIONE.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We measured the extracellular (interstitial) pH (pHe) of RG-2 rat gliomas using H+-sensitive microelectrodes and estimated the volume of tumor extracellular space based on the tissue-plasma ratio of [14C]sucrose." | 3.67 | In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. II: Characterization of the extracellular fluid compartment using pH-sensitive microelectrodes and [14C]sucrose. ( Arnold, JB; Kraig, RP; Rottenberg, DA, 1986) |
| "Thus, the RG-2 glioma is not more "acidic" than adjacent brain tissue and its "alkaline" pHt probably reflects a large extracellular water content and plasma-like extracellular pH." | 1.27 | In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. ( Arnold, JB; Junck, L; Rottenberg, DA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rottenberg, DA | 4 |
| Ginos, JZ | 2 |
| Kearfott, KJ | 2 |
| Junck, L | 3 |
| Bigner, DD | 1 |
| Lomneth, R | 1 |
| Medrano, S | 1 |
| Gruenstein, EI | 1 |
| Arnold, JB | 2 |
| Kraig, RP | 1 |
| Dhawan, V | 1 |
| Jarden, JO | 1 |
5 other studies available for dimethadione and Brain Neoplasms
| Article | Year |
|---|---|
In vivo measurement of regional brain tissue pH using positron emission tomography.
Topics: Brain; Brain Chemistry; Brain Neoplasms; Dimethadione; Humans; Hydrogen-Ion Concentration; Tomograph | 1984 |
The role of transmembrane pH gradients in the lactic acid induced swelling of astrocytes.
Topics: Alanine; Astrocytes; Brain Neoplasms; Cell Membrane; Dimethadione; Glioma; Humans; Hydrogen-Ion Conc | 1990 |
In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. II: Characterization of the extracellular fluid compartment using pH-sensitive microelectrodes and [14C]sucrose.
Topics: Animals; Autoradiography; Brain; Brain Neoplasms; Dimethadione; Extracellular Space; Glioma; Hydroge | 1986 |
In vivo measurement of brain tumor pH using [11C]DMO and positron emission tomography.
Topics: Adult; Brain Neoplasms; Carbon Radioisotopes; Dimethadione; Female; Humans; Hydrogen-Ion Concentrati | 1985 |
In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography.
Topics: Animals; Autoradiography; Brain Chemistry; Brain Neoplasms; Carbon Radioisotopes; Dimethadione; Extr | 1985 |