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dimercaprol and Symptom Cluster

dimercaprol has been researched along with Symptom Cluster in 8 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research Excerpts

ExcerptRelevanceReference
"Treatment with dimercaprol produced a clinical improvement on the fourth day with a fall in blood mercury from 3."1.26[Encephalopathy due to organomercuric compounds]. ( Gil, R; Lefèvre, JP, 1977)
"Fifty-eight patients with Wilson's disease are reviewed, of whom 25 symptomatic patients experienced liver disease first and 28, brain disease."1.26Clinical spectrum of Wilson's disease (hepatolenticular degeneration). ( Dobyns, WB; Goldstein, NP; Gordon, H, 1979)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ERDMANN-MULLER, GJ1
HORNBOSTEL, H2
SALZER, HM1
Lefèvre, JP1
Gil, R1
Dobyns, WB1
Goldstein, NP1
Gordon, H1
Niederberger, P1
Sutter, B1
Fraisse, P1
Tritschler, JL1
Meyer, R1
Kuntz, JL1
Asch, L1
Vernay, D1
Dubost, JJ1
Thevenet, JP1
Sauvezie, B1
Rampon, S1
Fejerman, N1
Gimenez, ER1
Vallejo, NE1
Medina, CS1

Other Studies

8 other studies available for dimercaprol and Symptom Cluster

ArticleYear
[BAL therapy and copper excretion in hepatolenticular syndrome].
    Klinische Wochenschrift, 1953, Dec-01, Volume: 31, Issue:45-46

    Topics: Biological Transport; Body Fluids; Copper; Dimercaprol; Hepatolenticular Degeneration; Syndrome; Uri

1953
BAL in the treatment of neurological syndromes.
    Diseases of the nervous system, 1954, Volume: 15, Issue:3

    Topics: Central Nervous System Diseases; Databases, Genetic; Dimercaprol; Syndrome

1954
[Recent findings on the hepatolenticular syndrome].
    Schweizerische medizinische Wochenschrift, 1954, Jan-02, Volume: 84, Issue:1

    Topics: Dimercaprol; Hepatolenticular Degeneration; Syndrome

1954
[Encephalopathy due to organomercuric compounds].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1977, Jan-16, Volume: 53, Issue:3

    Topics: Adult; Agricultural Workers' Diseases; Brain Diseases; Dimercaprol; Humans; Male; Mercury Poisoning;

1977
Clinical spectrum of Wilson's disease (hepatolenticular degeneration).
    Mayo Clinic proceedings, 1979, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Brain Diseases; Child; Copper; Cornea; Dimercaprol; Female; Hepatolenticular Dege

1979
[Morvan's fibrillary chorea following chrysotherapy].
    Revue du rhumatisme et des maladies osteo-articulaires, 1986, Volume: 53, Issue:11

    Topics: Arthritis, Rheumatoid; Chorea; Dimercaprol; Female; Humans; Leg; Metalloproteins; Middle Aged; Myocl

1986
"Chorée fibrillaire de Morvan" followed by Guillain-Barré syndrome in a patient receiving gold therapy.
    Arthritis and rheumatism, 1986, Volume: 29, Issue:11

    Topics: Arthritis, Rheumatoid; Chorea; Dimercaprol; Female; Gold; Humans; Leg; Middle Aged; Myoclonus; Organ

1986
Lennox's syndrome and lead intoxication.
    Pediatrics, 1973, Volume: 52, Issue:2

    Topics: Anticonvulsants; Child; Child, Preschool; Clinical Enzyme Tests; Dimercaprol; Edetic Acid; Electroen

1973