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dimercaprol and Shock, Septic

dimercaprol has been researched along with Shock, Septic in 1 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.

Research Excerpts

ExcerptRelevanceReference
"Three patients receiving gold salt treatment for rheumatoid arthritis developed severe aplastic anemia."1.27Gold-induced aplastic anemia. ( Immesoete, C; Joos, R; Proot, F; Williame, LM, 1987)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Williame, LM1
Joos, R1
Proot, F1
Immesoete, C1

Other Studies

1 other study available for dimercaprol and Shock, Septic

ArticleYear
Gold-induced aplastic anemia.
    Clinical rheumatology, 1987, Volume: 6, Issue:4

    Topics: Adult; Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Dimercaprol; Female; Humans; Metalloproteins;

1987